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JPS5659751A - Preparation of 1-aryl-4-carboxytriethylammonium-5-(3'-methoxy-4'-oxyphenyl)-2-pyrrolidinone - Google Patents

Preparation of 1-aryl-4-carboxytriethylammonium-5-(3'-methoxy-4'-oxyphenyl)-2-pyrrolidinone

Info

Publication number
JPS5659751A
JPS5659751A JP13568779A JP13568779A JPS5659751A JP S5659751 A JPS5659751 A JP S5659751A JP 13568779 A JP13568779 A JP 13568779A JP 13568779 A JP13568779 A JP 13568779A JP S5659751 A JPS5659751 A JP S5659751A
Authority
JP
Japan
Prior art keywords
triethylamine
compound shown
formula
give
succinic anhydride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13568779A
Other languages
Japanese (ja)
Other versions
JPS6033384B2 (en
Inventor
Kazuo Sugiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KINKIDAIGAKU
Original Assignee
KINKIDAIGAKU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KINKIDAIGAKU filed Critical KINKIDAIGAKU
Priority to JP13568779A priority Critical patent/JPS6033384B2/en
Publication of JPS5659751A publication Critical patent/JPS5659751A/en
Publication of JPS6033384B2 publication Critical patent/JPS6033384B2/en
Expired legal-status Critical Current

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  • Pyrrole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PURPOSE: To obtain the titled substance having improved antibacterial action, stable pharmaceutical effect and prolonged effectiveness, by subjecting triethylamine to addition reaction with the reaction product of 4-oxy-3-methoxybenzylidene-4'- substituted aniline and succinic anhydride.
CONSTITUTION: A compound shown by the formula I (X is H, CH3, or Cl) is reacted with succinic anhydride in dried xylene under reflux at elevated temperature for 40hr to give a compound shown by the formula II. This compound is dissolved in dried THF, and triethylamine is added dropwise little by little for 4hr to the prepared solution under cooling with ice with stirring. After adding dropwise, the solution is allowed to stand for 24hr, and the solvent and the remaining triethylamine are distilled away under reduced pressure at low temperature, to give a compound shown by the formula III.
COPYRIGHT: (C)1981,JPO&Japio
JP13568779A 1979-10-20 1979-10-20 Method for producing 1-aryl-4-carboxytriethylammonium-5-(3'-methoxy-4'-oxyphenyl)-2-pyrrolidinone Expired JPS6033384B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13568779A JPS6033384B2 (en) 1979-10-20 1979-10-20 Method for producing 1-aryl-4-carboxytriethylammonium-5-(3'-methoxy-4'-oxyphenyl)-2-pyrrolidinone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13568779A JPS6033384B2 (en) 1979-10-20 1979-10-20 Method for producing 1-aryl-4-carboxytriethylammonium-5-(3'-methoxy-4'-oxyphenyl)-2-pyrrolidinone

Publications (2)

Publication Number Publication Date
JPS5659751A true JPS5659751A (en) 1981-05-23
JPS6033384B2 JPS6033384B2 (en) 1985-08-02

Family

ID=15157559

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13568779A Expired JPS6033384B2 (en) 1979-10-20 1979-10-20 Method for producing 1-aryl-4-carboxytriethylammonium-5-(3'-methoxy-4'-oxyphenyl)-2-pyrrolidinone

Country Status (1)

Country Link
JP (1) JPS6033384B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639529A (en) * 1982-02-19 1987-01-27 The Purdue Frederick Company Analgesic and anti-inflammatory compounds
JPS63264458A (en) * 1986-12-03 1988-11-01 Tanabe Seiyaku Co Ltd Lactam derivative

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01169291U (en) * 1988-05-20 1989-11-29

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639529A (en) * 1982-02-19 1987-01-27 The Purdue Frederick Company Analgesic and anti-inflammatory compounds
JPS63264458A (en) * 1986-12-03 1988-11-01 Tanabe Seiyaku Co Ltd Lactam derivative

Also Published As

Publication number Publication date
JPS6033384B2 (en) 1985-08-02

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