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JPS565484A - Cephalosporin derivative and its salt - Google Patents

Cephalosporin derivative and its salt

Info

Publication number
JPS565484A
JPS565484A JP8170179A JP8170179A JPS565484A JP S565484 A JPS565484 A JP S565484A JP 8170179 A JP8170179 A JP 8170179A JP 8170179 A JP8170179 A JP 8170179A JP S565484 A JPS565484 A JP S565484A
Authority
JP
Japan
Prior art keywords
formula
carboxylic acid
formyl
derivative
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8170179A
Other languages
Japanese (ja)
Inventor
Junji Nakano
Toshio Furumiya
Yoshiyuki Takase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dainippon Pharmaceutical Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd filed Critical Dainippon Pharmaceutical Co Ltd
Priority to JP8170179A priority Critical patent/JPS565484A/en
Publication of JPS565484A publication Critical patent/JPS565484A/en
Pending legal-status Critical Current

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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The titled compound of formula I (R is formyl group, etc.; R' is acetoxy group, etc.).
EXAMPLE: 7-[ D-α-[ 1, 4-Dihydro-6-fluoro-7-( 4-formyl-1-piperazinyl )-4-oxo-1, 8- naphthyridine-3-carboxamido ]-α-p-hydroxyphenylacetamido ]-3-( 1-carboxymethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid sodium salt.
USE: An antimicrobial or its intermediate, having a great antimicrobial activity against Gram-positive and Gram-negative bacteria, particularly Pseudomonas aeruginosa, with low toxicity and improved solubility.
PROCESS: A carboxylic acid of formula II or its reactive derivative at the carboxyl group is reacted with a cephalosporin of formula III or its derivative to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP8170179A 1979-06-27 1979-06-27 Cephalosporin derivative and its salt Pending JPS565484A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8170179A JPS565484A (en) 1979-06-27 1979-06-27 Cephalosporin derivative and its salt

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8170179A JPS565484A (en) 1979-06-27 1979-06-27 Cephalosporin derivative and its salt

Publications (1)

Publication Number Publication Date
JPS565484A true JPS565484A (en) 1981-01-20

Family

ID=13753676

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8170179A Pending JPS565484A (en) 1979-06-27 1979-06-27 Cephalosporin derivative and its salt

Country Status (1)

Country Link
JP (1) JPS565484A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5841120U (en) * 1981-09-11 1983-03-18 株式会社クボタ rice transplanter
WO1990004595A1 (en) * 1988-10-24 1990-05-03 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial fluoroquinolonyl cephems

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5841120U (en) * 1981-09-11 1983-03-18 株式会社クボタ rice transplanter
JPH0122410Y2 (en) * 1981-09-11 1989-07-04
WO1990004595A1 (en) * 1988-10-24 1990-05-03 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial fluoroquinolonyl cephems

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