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JPS5625180A - Manufacture of novel 66azaa3hh1*44benzodiazepine - Google Patents

Manufacture of novel 66azaa3hh1*44benzodiazepine

Info

Publication number
JPS5625180A
JPS5625180A JP5022180A JP5022180A JPS5625180A JP S5625180 A JPS5625180 A JP S5625180A JP 5022180 A JP5022180 A JP 5022180A JP 5022180 A JP5022180 A JP 5022180A JP S5625180 A JPS5625180 A JP S5625180A
Authority
JP
Japan
Prior art keywords
66azaa3hh1
novel
manufacture
novel 66azaa3hh1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5022180A
Other languages
Japanese (ja)
Other versions
JPS5742638B2 (en
Inventor
Fuon Beebenburuku Buarutaa
Otsufuerumansu Heriberuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH filed Critical Degussa GmbH
Publication of JPS5625180A publication Critical patent/JPS5625180A/en
Publication of JPS5742638B2 publication Critical patent/JPS5742638B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
JP5022180A 1971-12-09 1980-04-15 Manufacture of novel 66azaa3hh1*44benzodiazepine Granted JPS5625180A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1060471A AT333284B (en) 1971-12-09 1971-12-09 PROCESS FOR THE PREPARATION OF NEW 6-AZA-3H-1,4-BENZODIAZEPINES, THEIR OPTICAL ISOMERS AND THEIR SALTS

Publications (2)

Publication Number Publication Date
JPS5625180A true JPS5625180A (en) 1981-03-10
JPS5742638B2 JPS5742638B2 (en) 1982-09-09

Family

ID=3623479

Family Applications (4)

Application Number Title Priority Date Filing Date
JP12387872A Expired JPS569509B2 (en) 1971-12-09 1972-12-09
JP5022280A Granted JPS55147282A (en) 1971-12-09 1980-04-15 Manufacture of novel 66azaa3hh1*44benzodiazepine
JP5022180A Granted JPS5625180A (en) 1971-12-09 1980-04-15 Manufacture of novel 66azaa3hh1*44benzodiazepine
JP5022380A Granted JPS5625181A (en) 1971-12-09 1980-04-15 Manufacture of novel 66azaa3hh1*44benzodiazepine

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP12387872A Expired JPS569509B2 (en) 1971-12-09 1972-12-09
JP5022280A Granted JPS55147282A (en) 1971-12-09 1980-04-15 Manufacture of novel 66azaa3hh1*44benzodiazepine

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP5022380A Granted JPS5625181A (en) 1971-12-09 1980-04-15 Manufacture of novel 66azaa3hh1*44benzodiazepine

Country Status (26)

Country Link
JP (4) JPS569509B2 (en)
AR (3) AR201201A1 (en)
AT (4) AT332877B (en)
AU (1) AU473253B2 (en)
BE (1) BE792541A (en)
CH (4) CH603644A5 (en)
CS (1) CS212736B2 (en)
DD (1) DD105448A5 (en)
DE (1) DE2259471C2 (en)
DK (1) DK138425B (en)
EG (1) EG10918A (en)
ES (2) ES409089A1 (en)
FI (1) FI54710C (en)
FR (1) FR2162482B1 (en)
GB (1) GB1400755A (en)
HU (1) HU169468B (en)
IL (1) IL41034A (en)
IT (1) IT1035053B (en)
NL (1) NL171986C (en)
NO (1) NO137094C (en)
PL (3) PL91828B1 (en)
RO (4) RO62312A (en)
SE (1) SE404803B (en)
SU (4) SU468423A3 (en)
YU (2) YU305972A (en)
ZA (1) ZA728497B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60132610A (en) * 1983-12-20 1985-07-15 Japan Organo Co Ltd Sludge dehydrating apparatus

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2364636C2 (en) * 1973-12-24 1982-11-04 Degussa Ag, 6000 Frankfurt Process for the preparation of 2-benzoyl-6-chloro-3-nitro-pyridines
EP0032516B1 (en) * 1980-01-16 1984-05-02 Lacer, S.A. New 2-halo-pyridines, their production and pharmaceutical compositions
JPS6219221A (en) * 1985-07-16 1987-01-28 Chiyoda Chem Eng & Constr Co Ltd Filtration method and apparatus for removing fine grain incorporated in raw liquid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3314941A (en) * 1964-06-23 1967-04-18 American Cyanamid Co Novel substituted pyridodiazepins
US3523939A (en) * 1967-07-03 1970-08-11 Hoffmann La Roche 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60132610A (en) * 1983-12-20 1985-07-15 Japan Organo Co Ltd Sludge dehydrating apparatus

Also Published As

Publication number Publication date
AT332877B (en) 1976-10-25
ZA728497B (en) 1973-09-26
SU674675A3 (en) 1979-07-15
DD105448A5 (en) 1974-04-20
RO65263A (en) 1983-07-07
AU4993172A (en) 1974-06-13
JPS55147282A (en) 1980-11-17
FI54710C (en) 1979-02-12
NO137094C (en) 1977-12-28
CS212736B2 (en) 1982-03-26
AT338798B (en) 1977-09-12
ES409090A1 (en) 1975-10-16
RO65264A (en) 1979-08-15
RO65263B (en) 1983-06-30
NL171986C (en) 1983-06-16
FI54710B (en) 1978-10-31
CH603645A5 (en) 1978-08-31
IL41034A (en) 1976-10-31
ES409089A1 (en) 1975-10-16
JPS5625181A (en) 1981-03-10
PL91828B1 (en) 1977-03-31
ATA902174A (en) 1976-02-15
BE792541A (en) 1973-06-08
RO62312A (en) 1977-12-15
DK138425B (en) 1978-09-04
CH603644A5 (en) 1978-08-31
EG10918A (en) 1981-12-31
YU116881A (en) 1984-02-29
AU473253B2 (en) 1976-06-17
HU169468B (en) 1976-11-28
ATA902274A (en) 1976-02-15
ATA902074A (en) 1977-01-15
SU564809A3 (en) 1977-07-05
AR201201A1 (en) 1975-02-21
JPS5742638B2 (en) 1982-09-09
AT333284B (en) 1976-11-10
PL91876B1 (en) 1977-03-31
JPS5742639B2 (en) 1982-09-09
DE2259471C2 (en) 1982-08-19
NO137094B (en) 1977-09-19
AR200309A1 (en) 1974-10-31
JPS569509B2 (en) 1981-03-02
AT332878B (en) 1976-10-25
SE404803B (en) 1978-10-30
FR2162482B1 (en) 1976-03-05
CH605946A5 (en) 1978-10-13
IT1035053B (en) 1979-10-20
ATA1060471A (en) 1976-03-15
DK138425C (en) 1979-02-12
RO67345A (en) 1980-07-15
YU305972A (en) 1982-02-28
SU574156A3 (en) 1977-09-25
DE2259471A1 (en) 1973-06-14
CH594665A5 (en) 1978-01-13
NL171986B (en) 1983-01-17
JPS5744678B2 (en) 1982-09-22
FR2162482A1 (en) 1973-07-20
PL89682B1 (en) 1976-12-31
GB1400755A (en) 1975-07-23
NL7216621A (en) 1973-06-13
JPS4864096A (en) 1973-09-05
AR203311A1 (en) 1975-08-29
SU468423A3 (en) 1975-04-25
IL41034A0 (en) 1973-02-28

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