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JPS56131514A - Ketoprofen composition for rectum administration - Google Patents

Ketoprofen composition for rectum administration

Info

Publication number
JPS56131514A
JPS56131514A JP3273980A JP3273980A JPS56131514A JP S56131514 A JPS56131514 A JP S56131514A JP 3273980 A JP3273980 A JP 3273980A JP 3273980 A JP3273980 A JP 3273980A JP S56131514 A JPS56131514 A JP S56131514A
Authority
JP
Japan
Prior art keywords
ketoprofen
administration
triglyceride
fatty acid
polyethylene glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3273980A
Other languages
Japanese (ja)
Other versions
JPH0233010B2 (en
Inventor
Kotaro Yasuda
Takio Iwamoto
Ryoichi Ishitani
Masami Matsushima
Kazuhiko Kubota
Hatsuyo Maeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IWAKI SEIYAKU KK
Nissan Chemical Corp
Original Assignee
IWAKI SEIYAKU KK
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IWAKI SEIYAKU KK, Nissan Chemical Corp filed Critical IWAKI SEIYAKU KK
Priority to JP3273980A priority Critical patent/JPS56131514A/en
Publication of JPS56131514A publication Critical patent/JPS56131514A/en
Publication of JPH0233010B2 publication Critical patent/JPH0233010B2/ja
Granted legal-status Critical Current

Links

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  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: The titled composition capable of preventing a gastroenteric disorder, having improved ketoprofen adsorption, comprising ketoprofen, polyethylene glycol monostearate, bleached bees wax, and a triglyceride of a middle-chain fatty acid.
CONSTITUTION: 100pts.wt. ketoprofen is blended with 52W62pts.wt. polyethylene glycol monostearate (preferably a polymerization degree of ethylene 40), 130W 150pts.wt. bleached bees wax, and 1,700W1,800pts.wt. triglyceride of a middle- chain fatty acid, etc., to give a ketoprofen composition for rectum administration. This is an oily suspension, and the administration to the human body is pharmaceutical preparation for enema medication or a suppository of a sofy gelatin capsule. This pharmaceutical preparation has about double the blood concentration of ketoprofen of other pharmaceutical preparations so that an amount of administration can be rduced. Consequently, a mucosa damage by a drug at the absorption part can be lowered.
COPYRIGHT: (C)1981,JPO&Japio
JP3273980A 1980-03-17 1980-03-17 Ketoprofen composition for rectum administration Granted JPS56131514A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3273980A JPS56131514A (en) 1980-03-17 1980-03-17 Ketoprofen composition for rectum administration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3273980A JPS56131514A (en) 1980-03-17 1980-03-17 Ketoprofen composition for rectum administration

Publications (2)

Publication Number Publication Date
JPS56131514A true JPS56131514A (en) 1981-10-15
JPH0233010B2 JPH0233010B2 (en) 1990-07-25

Family

ID=12367196

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3273980A Granted JPS56131514A (en) 1980-03-17 1980-03-17 Ketoprofen composition for rectum administration

Country Status (1)

Country Link
JP (1) JPS56131514A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0087062A2 (en) * 1982-02-16 1983-08-31 Dolorgiet GmbH & Co. KG Pharmaceutical composition containing ibuprofen for external application, and method of preparing the same
EP0210759A2 (en) * 1985-06-28 1987-02-04 R.P. Scherer Corporation Suppositories containing analgesics, antipyretics or anti-inflammatory agents
FR2660555A1 (en) * 1990-04-06 1991-10-11 Rhone Poulenc Sante KETOPROFENE OIL CAPSULE.
EP1319397A4 (en) * 2000-09-21 2004-02-04 Taisho Pharmaceutical Co Ltd Suppositories sustained in the lower rectum
US7635675B2 (en) 2003-08-13 2009-12-22 Biocon Limited Micro-particle fatty acid salt solid dosage formulations for therapeutic agents

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5012222A (en) * 1973-01-27 1975-02-07

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5012222A (en) * 1973-01-27 1975-02-07

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0087062A2 (en) * 1982-02-16 1983-08-31 Dolorgiet GmbH & Co. KG Pharmaceutical composition containing ibuprofen for external application, and method of preparing the same
EP0210759A2 (en) * 1985-06-28 1987-02-04 R.P. Scherer Corporation Suppositories containing analgesics, antipyretics or anti-inflammatory agents
FR2660555A1 (en) * 1990-04-06 1991-10-11 Rhone Poulenc Sante KETOPROFENE OIL CAPSULE.
EP1319397A4 (en) * 2000-09-21 2004-02-04 Taisho Pharmaceutical Co Ltd Suppositories sustained in the lower rectum
AU2001288039B2 (en) * 2000-09-21 2005-09-15 Taisho Pharmaceutical Co., Ltd. Suppositories sustained in the lower rectum
US7635675B2 (en) 2003-08-13 2009-12-22 Biocon Limited Micro-particle fatty acid salt solid dosage formulations for therapeutic agents

Also Published As

Publication number Publication date
JPH0233010B2 (en) 1990-07-25

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