JPS5589221A - Antihistaminic agent - Google Patents
Antihistaminic agentInfo
- Publication number
- JPS5589221A JPS5589221A JP16155678A JP16155678A JPS5589221A JP S5589221 A JPS5589221 A JP S5589221A JP 16155678 A JP16155678 A JP 16155678A JP 16155678 A JP16155678 A JP 16155678A JP S5589221 A JPS5589221 A JP S5589221A
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- effective component
- phenylalkyl
- acid addition
- addition salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: An antihistaminic agent knows as a medicine having β-adrenergic nerve- blocking activity, containing a carbostyryl derivative or its acid addition salt as an effective component.
CONSTITUTION: An antihistaminic agent containing, as an effective component, a compound of formula (R1 is H, lower alkyl, or phenylalkyl; R2 is H, lower alkyl, phenylalkyl, lower alkenyl, etc.; R3,4 are H, lower alkyl, cycloalkyl, etc., or R3 and R4 may together with adjacent N atom form a five- or six-membered saturated hetero-ring; the dotted line is a single or double bond) or its acid addition salt. Dose: 40μgW2mg/day for oral administration or injection. Administered 3W4 times daily. The content of the effective component in the whole composition is 1W 70wt%. The agent is effective for the remedy or prevention of allergic diseases of the respiratory tract, hay fever, atopic dermatitis, etc.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16155678A JPS5589221A (en) | 1978-12-28 | 1978-12-28 | Antihistaminic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16155678A JPS5589221A (en) | 1978-12-28 | 1978-12-28 | Antihistaminic agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5589221A true JPS5589221A (en) | 1980-07-05 |
JPS6132286B2 JPS6132286B2 (en) | 1986-07-25 |
Family
ID=15737345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16155678A Granted JPS5589221A (en) | 1978-12-28 | 1978-12-28 | Antihistaminic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5589221A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5780371A (en) * | 1980-11-05 | 1982-05-19 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
US4455422A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and pharmaceutical composition containing the same |
US4482560A (en) * | 1979-09-18 | 1984-11-13 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives, and antihistaminic agents containing the same |
US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
-
1978
- 1978-12-28 JP JP16155678A patent/JPS5589221A/en active Granted
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4482560A (en) * | 1979-09-18 | 1984-11-13 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives, and antihistaminic agents containing the same |
US4455422A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and pharmaceutical composition containing the same |
US4619932A (en) * | 1980-03-06 | 1986-10-28 | Otsuka Pharmaceutical Co., Ltd. | Novel carbostyril derivatives, process for producing thereof and pharmaceutical composition containing the same |
JPS5780371A (en) * | 1980-11-05 | 1982-05-19 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
Also Published As
Publication number | Publication date |
---|---|
JPS6132286B2 (en) | 1986-07-25 |
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