JPS5558093A - Production of uricase - Google Patents
Production of uricaseInfo
- Publication number
- JPS5558093A JPS5558093A JP13239978A JP13239978A JPS5558093A JP S5558093 A JPS5558093 A JP S5558093A JP 13239978 A JP13239978 A JP 13239978A JP 13239978 A JP13239978 A JP 13239978A JP S5558093 A JPS5558093 A JP S5558093A
- Authority
- JP
- Japan
- Prior art keywords
- uricase
- uric acid
- streptomyces
- cultured
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010092464 Urate Oxidase Proteins 0.000 title abstract 5
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 abstract 5
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 abstract 5
- 229940116269 uric acid Drugs 0.000 abstract 5
- 241000187747 Streptomyces Species 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 150000002772 monosaccharides Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
Landscapes
- Enzymes And Modification Thereof (AREA)
Abstract
PURPOSE: A bacterium assimilating uric acid and producing uricase outside the cells, which belongs to Streptomyces, is cultured to produce uricase with high specificity to uric acid.
CONSTITUTION: A bacterium of Streptomyces, which assimilates uric acid and produces uricase outside the cells, that is Streptomyces u-1 (FERM 4676), is cultured using saccharides as soluble polysaccharide or monosaccharide and uric acid as sources of carbon and nitrogen and uricase with high specificity to uric acid is collected from the filtrate of the culture medium.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13239978A JPS5558093A (en) | 1978-10-27 | 1978-10-27 | Production of uricase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13239978A JPS5558093A (en) | 1978-10-27 | 1978-10-27 | Production of uricase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5558093A true JPS5558093A (en) | 1980-04-30 |
| JPS5643230B2 JPS5643230B2 (en) | 1981-10-09 |
Family
ID=15080474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13239978A Granted JPS5558093A (en) | 1978-10-27 | 1978-10-27 | Production of uricase |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5558093A (en) |
-
1978
- 1978-10-27 JP JP13239978A patent/JPS5558093A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5643230B2 (en) | 1981-10-09 |
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