Nothing Special   »   [go: up one dir, main page]

JPS54106458A - Sesquiterpene derivative - Google Patents

Sesquiterpene derivative

Info

Publication number
JPS54106458A
JPS54106458A JP1467478A JP1467478A JPS54106458A JP S54106458 A JPS54106458 A JP S54106458A JP 1467478 A JP1467478 A JP 1467478A JP 1467478 A JP1467478 A JP 1467478A JP S54106458 A JPS54106458 A JP S54106458A
Authority
JP
Japan
Prior art keywords
together form
compound
sesquiterpene derivative
group
dihydrobenzofuran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1467478A
Other languages
Japanese (ja)
Other versions
JPS5936913B2 (en
Inventor
Masanao Shinohara
Hirotsugu Kaise
Yoshimasa Nakano
Taketoshi Izawa
Yasuo Oshiro
Kazunari Miyazaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP53014674A priority Critical patent/JPS5936913B2/en
Priority to FR7813932A priority patent/FR2405941A1/en
Priority to NZ187243A priority patent/NZ187243A/en
Priority to DK212778A priority patent/DK154704C/en
Priority to PT68035A priority patent/PT68035B/en
Priority to FI781517A priority patent/FI69485C/en
Priority to CH519378A priority patent/CH641452A5/en
Priority to GB19140/78A priority patent/GB1601479A/en
Priority to AT0350878A priority patent/AT368188B/en
Priority to AR272175A priority patent/AR228011A1/en
Priority to NO781704A priority patent/NO152220C/en
Priority to NLAANVRAGE7805160,A priority patent/NL181804C/en
Priority to ES469821A priority patent/ES469821A1/en
Priority to CA000303381A priority patent/CA1142106A/en
Priority to IT49342/78A priority patent/IT1103138B/en
Priority to US05/906,300 priority patent/US4229466A/en
Priority to IE975/78A priority patent/IE46785B1/en
Priority to SE7805606A priority patent/SE439322B/en
Priority to DE2821403A priority patent/DE2821403C2/en
Priority to MX787121U priority patent/MX6053E/en
Priority to ES477771A priority patent/ES477771A1/en
Publication of JPS54106458A publication Critical patent/JPS54106458A/en
Priority to SE8305390A priority patent/SE452008B/en
Priority to NO834363A priority patent/NO154013C/en
Publication of JPS5936913B2 publication Critical patent/JPS5936913B2/en
Priority to FI853194A priority patent/FI79845C/en
Priority to DK058487A priority patent/DK155670C/en
Expired legal-status Critical Current

Links

Landscapes

  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

NEW MATERIAL:A compound of the formula or its salt (R1 is H, alkyl, alkanoyl; R2,3 are formyl, hydroxymethyl, OH, carboxyl, etc.; R2 and R3 may together form a lactone ring of -R9CH-O-CO-(R9 is H, OH); R4,6 are OH, alkanoyloxy; R5 is H; R4 and R5 may together form an oxo group; R4 and R6 may together form an alkylidenedioxy group.).
EXAMPLE: 6,7-Dihydroxy-2,5,5,8a-tetramethyl-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene-1-spiro-2'-(4',6',7'-trihydroxy-2',3'-dihydrobenzofuran).
USE: Remedy for nephritis, collagen disease, rheumatism, etc.
PROCESS: The objective compound can be prepared by culturing microorganisms belonging to Stachybotrys genus.
COPYRIGHT: (C)1979,JPO&Japio
JP53014674A 1977-06-30 1978-02-10 sesquiterpene derivatives Expired JPS5936913B2 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
JP53014674A JPS5936913B2 (en) 1978-02-10 1978-02-10 sesquiterpene derivatives
FR7813932A FR2405941A1 (en) 1977-06-30 1978-05-10 NEW SESQUITERPENIC DERIVATIVES USEFUL IN PARTICULAR AS INHIBITORS OF THE COMPLEMENTARY SYSTEM AND THEIR PREPARATION PROCESSES
NZ187243A NZ187243A (en) 1977-06-30 1978-05-11 Sesquiterpenes from culturing a stachybotrys genus or memmoniella simplex strain microorganism
DK212778A DK154704C (en) 1977-06-30 1978-05-12 PROCEDURE FOR THE PREPARATION OF A SESQUITER PENDANT OR SALTS THEREOF
PT68035A PT68035B (en) 1977-06-30 1978-05-12 Process for preparing sesquiterpene derivatives
FI781517A FI69485C (en) 1977-06-30 1978-05-12 PROCEDURE FOR THE PHARMACOLOGICAL ACTIVATION OF ACTIVE 6,7-DIHYDROXY-2,5,5,8A-TETRAMETHYL-1,2,3,4,4A, 5,6,7,8,8A-DECAHYDRONAPHTHALEN-1-SPIRO-2 ' - (6 ', 7'-DIFORMYL-4'-hydroxy-2', 3'-DIHYDROBENSOFURAN)
CH519378A CH641452A5 (en) 1977-06-30 1978-05-12 SESQUITER PEN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
GB19140/78A GB1601479A (en) 1977-06-30 1978-05-12 6,7-dihydroxy-2,5,5,8a-tetramethyl-1,2,3,4,4a,5,6,7,8,8a-decahydro naphthalene-1-spiro-2'-(6',7'-diformyl-4'-hydroxy-2',3'-dihydrobenzofuran) and related compounds
AT0350878A AT368188B (en) 1977-06-30 1978-05-12 METHOD FOR PRODUCING SEQUITER PEN DERIVATIVES
AR272175A AR228011A1 (en) 1977-06-30 1978-05-12 PROCEDURE FOR THE PREPARATION OF SUBSTITUTED DERIVATIVES OF 2,5,5,8A-TETRAMETIL-1,2,3,4,4A, 5,6,7,8,8A-DECAHIDRONAFTALENO-1-SPIRO-2 '- (4' , 6 ', 7'-SUBSTITUTED-2', 3'-DIHYDROBENZOFURANE)
NO781704A NO152220C (en) 1977-06-30 1978-05-12 PROCEDURE FOR PREPARING SESQUITER PENDING DERIVATIVES
NLAANVRAGE7805160,A NL181804C (en) 1977-06-30 1978-05-12 SESQUITERPENE DERIVATIVES WITH ANTI-COMPLETION EFFECTS, METHOD FOR WINNING AN ANTI-COMPLETION EFFECTS AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
ES469821A ES469821A1 (en) 1977-06-30 1978-05-12 Sesquiterpene derivatives having anti-complementary activity
CA000303381A CA1142106A (en) 1977-06-30 1978-05-15 Sesquiterpene derivatives
IT49342/78A IT1103138B (en) 1977-06-30 1978-05-15 DERIVATIVES OF SESQUITERPENES AND PROCEDURE TO PREPARE AND APPLY THEM
US05/906,300 US4229466A (en) 1977-06-30 1978-05-15 Sesquiterpene derivatives having anti-complementary activity
IE975/78A IE46785B1 (en) 1977-06-30 1978-05-15 6,7-dihydroxy-2,5,5,8a-tetramethyl-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene-1-spiro-2'-(6',7'-diformyl-4'-hydroxy-2',3'-dihydrobenzofuran) and related compounds
SE7805606A SE439322B (en) 1977-06-30 1978-05-16 PROCEDURE FOR THE PREPARATION OF SESQUITE PENDER DERIVATIVES BY CULTIVATION OF A MICROORGANISM RELATED TO STACHYBOTRYS
DE2821403A DE2821403C2 (en) 1977-06-30 1978-05-16 Decahydronaphthalene-1-spiro-2'-dihydrobenzofurans, processes for their preparation and pharmaceutical compositions containing these compounds
MX787121U MX6053E (en) 1977-06-30 1978-06-02 MICROBIOLOGICAL PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF SESCHITERPEN
ES477771A ES477771A1 (en) 1977-06-30 1979-02-15 Sesquiterpene derivatives having anti-complementary activity
SE8305390A SE452008B (en) 1977-06-30 1983-09-30 PROCEDURE FOR THE PREPARATION OF SESKWITER PENDANT DERIVATIVES
NO834363A NO154013C (en) 1977-06-30 1983-11-28 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE SESQUITER PENDER DERIVATIVES.
FI853194A FI79845C (en) 1977-06-30 1985-08-20 PHARMACOLOGICAL ACTIVE 2,5,5,8A-TETRAMETHYL-1,2,3,4,4A, 5,6,7,8,8A--DECAHYDRONAPHTHALEN-1-SPIRO-2 '- (2', 3'-DIHYDROBENSOFURAN) -DERIVAT.
DK058487A DK155670C (en) 1977-06-30 1987-02-04 METHOD OF ANALOGUE FOR THE PREPARATION OF SESQUITER PENDING DERIVATIVES OR PHARMACEUTICAL ACCEPTABLE SALTS THEREOF

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53014674A JPS5936913B2 (en) 1978-02-10 1978-02-10 sesquiterpene derivatives

Publications (2)

Publication Number Publication Date
JPS54106458A true JPS54106458A (en) 1979-08-21
JPS5936913B2 JPS5936913B2 (en) 1984-09-06

Family

ID=11867758

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53014674A Expired JPS5936913B2 (en) 1977-06-30 1978-02-10 sesquiterpene derivatives

Country Status (1)

Country Link
JP (1) JPS5936913B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401767A (en) * 1988-04-15 1995-03-28 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US5656659A (en) * 1988-04-15 1997-08-12 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60241806A (en) * 1984-05-15 1985-11-30 株式会社スズテック Fertilizing apparatus
JPH0448657Y2 (en) * 1987-08-26 1992-11-17

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401767A (en) * 1988-04-15 1995-03-28 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US5656659A (en) * 1988-04-15 1997-08-12 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity

Also Published As

Publication number Publication date
JPS5936913B2 (en) 1984-09-06

Similar Documents

Publication Publication Date Title
ES482357A1 (en) Prostanoid compounds and compositions
ES8502987A1 (en) Benzo(b)thiophenes.
FR2404641A1 (en) PREPARATION OF FUROCOUMARINS FROM SUBSTITUTED COUMARINS
ES8701761A1 (en) Use of podophyllotoxin and derivatives thereof.
JPS56125335A (en) 1,4-naphthoquinone derivative, its preparation, and its use
JPS54106458A (en) Sesquiterpene derivative
ES8101592A1 (en) Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates.
JPS5265267A (en) Synthesis of spiro compounds
JPS5271456A (en) Synthesis of 1alpha-hydroxysteroid derivatives
JPS5227791A (en) Synthesis of cephalosporins
JPS5424888A (en) Novel 7alpha-methoxycephalosporins and their preparation
JPS5420195A (en) Preparation of guanosine-5'-monophosphoric acid
JPS5428893A (en) Preparation of sarcosine oxidase
JPS5414951A (en) Preparation of vitamin d derivatives
JPS5422391A (en) Preparation of novel 7alpha-methoxycephalosporins
JPS5417182A (en) Preparation of choline-oxidase
JPS5788142A (en) Preparation of cyclopentenolone compound
JPS53127892A (en) Preparation of alpha-methyl-l-dopa
JPS5492680A (en) Novel microorganism
JPS57212137A (en) Preparation of phenyl aliphtic acid derivative
JPS5515407A (en) 2-phenyl substituted 1-phthalazone derivative
JPS5432484A (en) Preparation of 5,8-dihydroxy-3,4-dihydro-carbostyril
JPS53141261A (en) Intermediates for prostaglandins and process for their preparation
JPS5377089A (en) Preparation of 2(s)-4'-carbomethoxy-buty1-1' -3(r), 4(s)-0-isopropylidene-tetrahydrothiophene
JPS5422369A (en) Novel delta-lactone and its preparation