JPH10109924A - Beautifying and whitening cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To prepare a beautifying and whitening cosmetic, safe in application to skin and containing an ingredient having great beautifying and whitening actions by compounding specific three kinds of plant extracts as active ingredients. SOLUTION: This beautifying and whitening cosmetic contains extracts from a seed of a watermelon, a seed of a pumpkin and the calyx of a petite tomato therein. The plants are extracted with a solvent such as water, ethanol, 1,3- butylene glycol, glycerol or acetone. For example, 300g pulverized seed of the watermelon (the dry seed) is added to a 50% aqueous solution of ethanol and the solution is then allowed to stand for 5 days under occasional stirring. The resultant solution is then filtered and the obtained filtrate is evaporated and freeze-dried to afford the extract. The extracts are obtained from the seed of the pumpkin the and calyx of the petite tomato according to similar operations. The beautifying and whitening cosmetic has actions on melamona cells B-16. The plants are parts to be discarded and resources can usefully be utilized.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a whitening cosmetic having a high whitening effect.

[0002]

[Prior art]

[0003] Various substances are known as substances having a whitening effect that can be used as raw materials for cosmetics and health foods. However, synthetic products have no guarantee of safety when applied to human skin for a long time. Use is being restricted. On the other hand, many natural products have a weak whitening effect. However, it is a natural product from the aspect of safety for human skin, and it has been eaten by humans for many years,
A substance that is guaranteed in terms of safety and has a strong whitening effect has been desired. Various substances are known as substances having a whitening effect that can be used as raw materials for cosmetics,
Not many were effective.

[0004]

SUMMARY OF THE INVENTION An object of the present invention is to provide a whitening cosmetic which is safe when applied to the skin and contains a component having a large whitening effect.

[0005]

Means for Solving the Problems In order to solve the above-mentioned problems, the present inventors have screened and examined plants which have been used for food for many years and which have been confirmed to be safe for the human body. I considered something. As a result, watermelon seeds, pumpkin seeds, and petit tomato stalks have a very strong whitening effect and are used as whitening cosmetic ingredients.
Alternatively, they have found that they are effective as quasi-drugs.

[0006] That is, the present invention is a whitening cosmetic containing a solvent extract of watermelon seeds, pumpkin seeds, and scabs of petit tomatoes.

[0007] Watermelon seeds, pumpkin seeds, and small tomatoes are used for extraction using a solvent. The solvent is water,
Ethanol, 1,3-butylene glycol, glycerin,
Acetone etc. can be used, but considering the elution efficiency, a mixture of a hydrophilic organic solvent and water is preferred, and the optimal combination is water:
An ethanol mixed solution is optimal. In the extraction, if stirring, ultrasonic waves or the like are used, the extraction efficiency is further improved, and it is necessary to combine them according to the application and necessity. Concentration and drying are performed depending on the application, such as when a dried product is desired. For this method, heat drying, spray drying, reduced pressure drying, freeze drying and the like can be used.

This substance is used as a raw material for other cosmetics such as liquid oils such as squalane and jojoba oil, solid oils such as beeswax and cetyl alcohol, various activators, humectants such as glycerin and 1,3-butylene glycol and various chemicals. It can be added to prepare cosmetic and health foods in various dosage forms. For example, use forms of tablets, biscuits, lotions, creams, emulsions, packs and the like may be considered according to the purpose.

[0009]

EXAMPLES An example of an actual use method will be described below, but the present invention is not limited to this example. Examples of the production of watermelon seeds, pumpkin seeds, and scallop extracts of petit tomatoes used in the present invention are shown below.

Production Example 1 300 g of a 50% aqueous ethanol solution was added to 20 g of crushed watermelon seeds (dry product), and left for 5 days with occasional stirring. After filtration, evaporation and freeze-drying.

Production Example 2 300 g of a 50% aqueous ethanol solution was added to 20 g of crushed pumpkin seeds (dry product), and left for 5 days with occasional stirring. After filtration, evaporation and freeze-drying.

Production Example 3 300 g of a 50% aqueous ethanol solution was added to 20 g of peta tomato fly (dried product) and left for 5 days with occasional stirring. After filtration, evaporation and freeze-drying.

Example 1 Lotion Olive Oil 0.5 50% Ethanol Extract of Preparation Example 1.0 Polyoxyethylene (20EO) Sorbitan Monostearate 2.0 Polyoxyethylene (60EO) Hardened Castor Oil 2.0 Ethanol 9.5 1.0% sodium hyaluronate aqueous solution 5.0 Purified water 80.0

Example-2 Cream A Squalane 20.0 Olive Oil 2.0 Mink Oil 1.0 Jojoba Oil 5.0 Beeswax 5.0 Cetostearyl Alcohol 2.0 Gryalin Monostearate 1.0 Sorbitan Monostearate 2 2.0 50% ethanol extract of Production Example 2 1.0 B Purified water 47.9 Polyoxyethylene (20EO) sorbitan monostearate 2.0 Polyoxyethylene (60EO) hydrogenated castor oil 1.0 Glycerin 5.0 1.0% aqueous solution of sodium hyaluronate 5.0 Methyl parahydroxybenzoate 0.1 A and B are each weighed, heated to 70 ° C., and A is gradually added to B while stirring, and then slowly. 30 with stirring
Cooled to ° C.

Example 3 was prepared by replacing the extract of Production Example 1 of Example 1 with the extract of Production Example 3.

B-16 Melanoma cell test A sample was added to EaglesMEM medium so as to have a predetermined concentration, and filtered with a sterilizing filter.
%, Adjusted to pH 7.6 ± 0.1 with sodium bicarbonate, dispensed into a Petri dish (6 ml), and suspended B-16 melanoma cell suspension (1 × 10 6 ce).
11 / ml), 5% CO2, 95%
The cells were cultured at 37 ° C for 3 days under air conditions. Further, medium exchange (Ea containing 10% fetal bovine serum containing the above sample)
glsMEM medium) and cultured for 3 days. (At this time, cell proliferation was determined.) The cells were peeled off, centrifuged, the cells were collected, and the whiteness was visually determined.

Whiteness Same degree as blank ± Slight whitening tendency + Clear whitening tendency ++ Strong whitening tendency +++

Cell proliferation 80% or more of blank A 60 to 80% of blank B 30 to 60% of blank C 30% or less of blank D

[0019]

[Table 1]

Usage test The face of each of six women was divided into left and right, one was used as an example and the other was used as a comparative example.
A questionnaire was given after March. In the comparative examples, various extracts of the production examples were replaced with water from the examples. (Comparative Examples 1 and 2) Twelve people were divided into two groups, and experiments were performed using the following samples. The following table summarizes the results of the questionnaire with the following criteria. Example is very good 3 Example is considerably better 2 Example is slightly better 1 No difference 0 Comparative example is slightly better -1 Comparative example is much better -2 Comparative example Is much better -3

[0021]

[0022]

[Effects] Whitening cosmetics containing watermelon seeds, pumpkin seeds, and petit tomato scabs have B-16 action and have a very high whitening effect. In addition, as a part of food, their safety has been confirmed by experience, and they are also discarded parts, which is a useful use of resources.

Claims (1)

[Claims] 1. Whitening cosmetics containing watermelon seeds, pumpkin seeds and scallop extract of petite tomato