JPH08143418A - Cosmetic - Google Patents

Abstract

PURPOSE: To obtain a safe carotenoid stable for a long period without emitting a malodor and causing any side effects by blending a lutein which is one kind of inexpensive and safe carotenoid therein. CONSTITUTION: This cosmetic is an inexpensive and safe cosmetic without emitting malodor and obtained by blending a lutein or a natural extract containing the lutein therein. One kind selected from a natural substance containing the lutein, an extract containing the lutein, synthetic lutein, an ester derivative of the lutein and a combination of a protein with the lutein or a mixture of two or more thereof is preferred as the lutein. Since five kinds of luteins A, B, D, F and G in the lutein are abundantly present in the natural world, extraction is readily carried out for easy utilization thereof. The lutein derived from the natural product is abundantly present in the chloroplast or a flower of higher plants such as a marigold and egg yolk, etc., of animals such as a hen's egg. A fatty acid ester of the lutein and the combination of the protein with the lutein can be used as the lutein. Furthermore, the usable dosage form of the cosmetic is a cream, a milky lotion, toilet water, a mousse, a pack, a lipstick, a foundation, etc.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic composition characterized by containing lutein which is one of carotenoids. By incorporating lutein, it is inexpensive, stable in cosmetic preparations, and safe carotenoid without side effects. The present invention relates to cosmetics containing.

[0002]

BACKGROUND OF THE INVENTION Carotenoids or their derivatives are precursors of vitamin A and are one of the nutrients useful for the human body. In recent years, however, carotenoids or astaxanthin, which is one of the carotenoids or its derivatives, has also been used in cosmetics. Attempts have been made to incorporate retinols for the purpose of skin anti-aging agents, antioxidants, radical scavengers, ultraviolet absorbers, natural coloring pigments, and the like.

Carotenoids such as astaxanthin are being applied to pharmaceuticals, foods, cosmetics, etc. because of their high antioxidant power and coloring ability (Japanese Patent Laid-Open No. 2-490).
91).

However, β- which has been compounded in conventional cosmetics
Carotene, astaxanthin, and retinol have a problem that they are easily oxidized due to problems such as their synthesis method and extraction method, and their stability is poor even when they are added to cosmetics, and a sufficient effect cannot be expected.

Further, since some astaxanthin is extracted from marine products, it has a fishy odor when added to cosmetics, and yeast-extracted astaxanthin has a strong sour yeast odor and causes a bad odor when added to cosmetics such as cosmetics. was there.

[0006] In order to solve these problems, efforts were made to reduce the malodor by improving the astaxanthin purification process, etc. (Japanese Patent Laid-Open No. 3-48884), but the malodor could not be completely removed, and the malodor problem was encountered. Could not be completely resolved.

On the other hand, artificially chemically synthesized astaxanthin has no problems such as odor, but is less stable and more expensive to manufacture than natural extracts, and since it is an artificial compound, it is expected that the safety assessment will be expensive. The application to cosmetics had to be limited.

Although retinols are relatively effective, they have a problem that side effects occur when used in large amounts as cosmetics.

[0009]

Problem to be Solved by the Invention The problem to be solved by the present invention is to provide a stable carotenoid-containing cosmetic which does not give off a bad odor, is inexpensive, and has no side effects.

[0010]

[Means for Solving the Problems] In view of such circumstances, the present inventors have conducted earnest studies to develop a safe carotenoid-containing cosmetic composition which does not emit a bad odor in the cosmetic composition, is stable for a long time, and has no side effects. As a result, they have found that when lutein, which is a kind of inexpensive and safe carotenoid, is incorporated into cosmetics, these problems are solved and the present invention was completed. That is, the present invention provides a stable, inexpensive and safe cosmetic composition which is characterized by containing lutein or a lutein-containing natural extract and which does not generate a bad odor. Hereinafter, the present invention will be described in more detail.

Lutein to be added to the cosmetic of the present invention is one of the carotenoid pigments belonging to xanthophyll, Iwanami Biology Encyclopedia, Second Edition, P1282, Iwanami Shoten, 1977,
There is a description of this in the public domain.

It has been confirmed by the following documents that the lutein of the present invention is metabolized to retinol in higher vertebrates and exerts the effect as vitamin A. Matsumoto, Pu
reAppl. Chem. , 63, 81-89 (199
1). And Katsu-yama, etc. , Com
p. Biochem Physiol. 90 B, 13
1-139 (1988). .

Lutein has stereoisomers, any of which can be used in the cosmetics of the present invention.
Among them, five kinds of lutein A, B, D, F, and G are abundant in the natural world, and therefore can be easily extracted and easily used in the present invention.

As the lutein used in the present invention, both synthetic and naturally derived lutein can be used.

Naturally-derived lutein is abundant in marigolds, chloroplasts of higher plants, flowers, egg yolks of animals such as chicken eggs, and any of the naturally-derived lutein that can be used in the present invention. There is no particular limitation as long as it is a natural product that can be used and is safe for the human body, and that it produces, accumulates, and contains lutein.

As the inexpensive and safe natural product containing lutein to be added to the cosmetics of the present invention, those already known in the following documents, patents and the like can be used, but are not particularly limited thereto.

As the lutein to be added to the cosmetic of the present invention, a lutein fatty acid ester derivative and a lutein protein conjugate can be used.

The fatty acid ester derivative of lutein to be blended in the cosmetic of the present invention is one in which a fatty acid is ester-bonded to one or two of the two hydroxyl groups of lutein, lutein palmitate, lutein dipalmitate, lutein acetate, It consists of a single substance or a composite of two or more types selected from lutein fatty acid esters such as lutein diacetate.

The protein conjugate of lutein contained in the cosmetic of the present invention is not particularly limited as long as it is a protein in which lutein and protein are bound.

Specific examples of lutein derived from natural products to be incorporated into the cosmetics of the present invention include dried fine powder of petals of marigold, which is an Asteraceae plant (manufactured by Daiwa Kasei, trade name: maritain gold), and its oil. There are soluble extracts and the like, but not limited thereto.

The lutein derived from a natural product to be added to the cosmetic of the present invention may be a dry finely ground product thereof,
Since lutein is an oil-soluble substance, if necessary, those natural products are extracted with lutein-containing components with an oil-soluble organic solvent such as acetone, alcohol, ethyl acetate, benzene, and chloroform, and harmful organic solvents are removed by a conventional method. Then, they can be used as lutein concentrates, or they can be used after being emulsified with the existing emulsifiers described in the collection of general-purpose cosmetic materials for Japan.

The extraction method, concentration method, purification method, etc. of lutein or its extract to be incorporated in the cosmetic of the present invention are described in JP-A-3-48.
The extraction method of natural carotenoids such as astaxanthin described in 884 and JP-A-2-49091 can also be used, and the conventional extraction method of an oil-soluble component from a natural product can also be used and is not particularly limited.

[0023] The amount of lutein or its extract to be incorporated in the cosmetic of the present invention in the cosmetic is determined by the degree of purification of the lutein,
The amount of lutein in cosmetics varies depending on the purity, but is 0.000
Lutein may be added so as to be 1% by weight or more. In order to sufficiently exhibit the anti-oxidation performance and coloring performance of lutein, it is advisable to add the lutein in an amount of 0.001 to 50% by weight, but it is not particularly limited thereto.

The dosage form of the cosmetic of the present invention is cream, emulsion,
In addition to general cosmetics such as lotion, mousse, pack, lipstick, foundation, powder, nail polish, eye color, toothpaste, mouthwash, oral cosmetics such as troches, bath cosmetics such as bath agents, shampoo and rinse. , Hair tonics, pomades, hair creams, hair styling agents, hair nourishing agents, hair restorers, hair dyes, scalp agents and the like.

To the cosmetics containing lutein of the present invention, a substance having antioxidant ability can be added as a stabilizer of lutein. For example, vitamin A, vitamin B, vitamin C, vitamin E and ester derivatives of the above vitamins can be added. , Cysteine, glutathione, glutathione peroxidase, citrates, phosphates, polyphenols, nucleic acids, herbal medicines, seaweeds, inorganic substances, and existing antioxidants that are described as having an antioxidant function in the Japanese Cosmetic Ingredient Standard One kind or a mixture of two or more kinds may be used in combination.

To the lutein-containing cosmetic of the present invention, in order to stabilize lutein and to enhance the value of the cosmetic, existing cosmetic raw materials such as an ultraviolet absorber whose substance name is described in the Japan General Cosmetic Raw Materials Collection are added. You can also do it.

[0027]

The lutein compounded in the cosmetic of the present invention is a relatively stable substance among carotenoids, and even if compounded in cosmetics, it has no side effects on the human body, no bad odor, and is supplied in large quantities at low cost. Since it is a carotenoid source capable of producing carotenoids, it is possible to produce high-quality carotenoid-containing cosmetics.

[0028]

EXAMPLES The present invention will now be described in detail with reference to Examples and Comparative Examples, but the present invention is not limited thereto.
In the following examples, marigold-extracted lutein (containing 5% by weight of lutein) manufactured by Daiwa Kasei Co., Ltd. was used, which is hereinafter abbreviated as lutein.

(1) Example 1 A cream was produced by a conventional method according to the following formulation. Squalane 10.0 Stearic acid 8.0 Stearyl alcohol 5.0 Beeswax 2.0 Propylene glycol monostearate 3.0 Polyoxyethylene cetyl ether 1.0 Lutein 3.0 Propylene glycol 12.0 Paraben 0.2 Perfume 0. 5 Purified water residue

(2) Example 2 An emulsion was prepared by a conventional method according to the following formulation. Avocado oil 10.0 Behenyl alcohol 0.5 Stearic acid 0.5 Glycerin fatty acid ester 1.0 Polyoxyethylene sorbitan fatty acid ester 1.0 Polyoxyethylene alkyl ether 0.5 Lutein 3.0 Propylene glycol 10.0 Paraben 0.2 Fragrance 0.5 Purified water Residue

(3) Example 3 A lotion was produced by a conventional method according to the following formulation. Ethanol 40.0 Propylene glycol 10.0 Castor oil 5.0 Lutein 3.0 Paraben 0.1 Purified water Residue

(4) Example 4 A pack was produced by a conventional method according to the following formulation. Polyvinyl alcohol 15.0 Sodium carboxymethylcellulose 5.0 Propylene glycol 3.0 Lutein 3.0 Ethanol 10.0 Paraben 0.1 Purified water Residue

(5) Example 5 A lipstick was produced by a conventional method according to the following formulation. Castor oil 45.3 Hexadecyl alcohol 25.0 Lanolin 4.0 Beeswax 5.0 Ozokerite 4.0 Candelilla wax 7.0 Carnauba wax 2.0 Paraben 0.1 Lutein 3.0 Titanium oxide 2.0 Red pigment 5. 0 Perfume 0.1 Moisture Residual

(6) Example 6 A foundation was produced by a conventional method according to the following formulation. Liquid paraffin 24.0 Isopropyl palmitate 15.0 Lanolin alcohol 2.0 Lanolin acetate 3.0 Microcrystalline wax 7.0 Ozokerite 8.0 Candelilla wax 0.5 Paraben 0.1 Lutein 3.0 Titanium oxide 15.0 Kaolin 15 0.0 Talc 6.0 Coloring pigment 4.0 Perfume 0.5 Moisture

(7) Example 7 A toothpaste was produced by a conventional method according to the following formulation. Dicalcium phosphate dihydrate 45.0% Sodium carboxymethylcellulose 0.5% Carrageenan 0.5% Glycerin 10.0% Sorbitol 10.0% Saccharin sodium 0.1% Sodium lauryl sulfate 2.0% Sodium chloride 2 0.0% α-tocopherol 0.5% Lutein 1.0% Preservative 0.1% Perfume 0.5% Purified water Residue

(8) Example 8 A mouthwash was prepared by a conventional method according to the following formulation. Ethyl alcohol 35.0% Glycerin 14.0% α-Tocopherol 0.5% Lutein 1.0% Perfume 0.1% Purified water Residue

(9) Example 9 A hair nourishing agent was produced by a conventional method according to the following formulation. Ethanol 60.0% Castor oil 4.0 Resorcinol 0.8 Methylparaben 0.1% Capsicum tincture 0.5% α-Tocopherol 0.5% Lutein 0.5% Purified water Residue

(10) Example 10 A shampoo was produced by a conventional method according to the following formulation. Lauryl sulfate triethanolamine salt 16.0% Lauric acid diethanolamide 3.0% Polyacrylic acid triethanolamine salt 0.5% Zinc pyridinium-1-thiol-N-oxide 1.0% Lutein 0.5% Dye Trace amount Fragrance 0.5% Purified water Residue

(11) Example 11 A rinse was manufactured by a conventional method according to the following formulation. Stearyl dimethylbenzylammonium chloride 1.4% Stearyl alcohol 0.6% Glyceryl monostearate 1.5% Sodium chloride 0.2% Lutein 1.0% Purified water Residue

(12) Example 12 A hair dye was produced by a conventional method according to the following formulation. Black No. 401 1.0% Isopropyl alcohol 21.0% Benzyl alcohol 6.0% Lutein 1.0% Carboxymethyl cellulose (5% aqueous solution) 20.0% Purified water 51.0%

(13) Example 13 A bath agent was produced by a conventional method according to the following formulation. Sodium hydrogen carbonate 35.5% Citric acid 38.0% Polyethylene glycol 2.0% Magnesium oxide 1.0% α-tocopherol 0.5% Lutein 25.0% Dye trace fragrance 2.0%

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Claims (2)

[Claims] 1. A cosmetic composition containing lutein. 2. The lutein comprises one or a mixture of two or more selected from lutein-containing natural products, lutein-containing extracts thereof, synthetic lutein, lutein ester derivatives, and lutein protein conjugates. Cosmetics