JP6665151B2 - Cleaning sheet - Google Patents

Description

  The present invention is not only a bactericidal property against bacteria and mold, an effect of inactivating viruses, but also can reduce wiping scars after wiping even in a high alkaline area, and has an antibacterial persistence, an antiviral persistence, and an effective disinfectant component. The present invention relates to a cleaning sheet that suppresses a decrease in the amount and discoloration of a base sheet and exhibits excellent disinfecting properties even for spores having high drug resistance.

  A so-called wet sheet (cleaning sheet) in which an aqueous solution containing a disinfectant or the like is impregnated into a nonwoven fabric is simple, easy to use, and disposable, so that a clean material can always be used. It is used in food factories, kitchens, and medical facilities to improve the environment.

  Patent Document 1 discloses an antibacterial agent composition containing ε-polylysine and / or a salt thereof, an electrolyte having a pH buffering ability, and an amino acid, and an antibacterial sheet-like article using the same.

  Patent Document 2 discloses a wiping sheet impregnated with water, a bactericidal preservative, a water-soluble humectant, and, if necessary, a detergent containing a solubilizing agent.

  Patent Literature 3 discloses a cleaning water impregnated with an aqueous impregnating liquid in which an aqueous impregnating liquid contains a silicone or an oily fragrance forming a peelable silicone film, and a part or all of the silicone or the oily fragrance is contained as an aqueous emulsion. Dissolvable wet sheets are disclosed.

  As a disinfectant impregnated in a cleaning sheet, a disinfectant containing a quaternary ammonium salt type surfactant is known. Patent Document 4 discloses a mixture of polyaminopropyl biguanide and a quaternary ammonium salt. A water-soluble composition for impregnating a fiber sheet having a pH of 3.5 to 4.5, containing sodium benzoate, citric acid, disodium ethylenediaminetetraacetate, a nonionic surfactant and water is disclosed.

JP 2004-67586 A JP 2006-230612 A JP 2011-30793 A JP 2013-151447 A

  However, the cleaning sheets described in Patent Literatures 1 to 3 do not have sufficient antibacterial properties against spores having high drug resistance and antiviral persistence.

On the other hand, a disinfectant containing a quaternary ammonium salt as described in Patent Document 4 has an excellent disinfecting effect, but when impregnated into a substrate sheet such as a nonwoven fabric, the disinfectant removes fibers from the substrate sheet. If the amount of the effective disinfectant component is reduced due to strong adsorption, and if the impregnated amount of the disinfectant is not increased, there is a possibility that the disinfection property and disinfection persistence may be reduced. When a recycled sheet, especially a rayon-containing fiber is used as the base sheet, the base sheet becomes hydrophilic, so that the impregnation amount of a water-based disinfectant can be increased. Since the adsorptivity of the active ingredient of the disinfectant is higher than that of other fibers, the amount of the active ingredient and the pH in the disinfectant impregnated in the base sheet are significantly reduced, and the disinfectant is impregnated on the base sheet. Even if the amount of the agent is increased, it is difficult to sufficiently improve the bactericidal property and its persistence, and it is also difficult to improve the antiviral property of the base sheet.
Further, by making the pH more alkaline, there is a problem that although the disinfection property is improved, traces of wiping after wiping are increased.

  Therefore, the problem to be solved by the present invention is not only the bactericidal property against bacteria and mold, the effect of inactivating the virus, but also can reduce the wiping scar after wiping even in a high alkaline area, the antibacterial persistence, the antiviral It is an object of the present invention to provide a cleaning sheet which has durability and does not have a risk of reducing the disinfecting effect and virus inactivating effect when impregnated in a base sheet.

  In order to solve the above problems, the present inventors have conducted intensive studies and have found that a quaternary ammonium salt type surfactant, potassium hydroxide, an aminocarboxylic acid type chelating agent, and water are impregnated in a base sheet, The present inventors have found that a cleaning sheet in which the pH of an aqueous disinfectant impregnated in a base sheet is 10.5 or more and 13.5 or less can solve the problem of the conventional cleaning sheet, and complete the present invention. Reached.

That is, the present invention
(1) In a cleaning sheet in which a base sheet capable of holding a liquid is impregnated with an aqueous disinfectant , the base sheet is impregnated with the aqueous disinfectant, and after 24 hours or more, the base sheet is impregnated. The aqueous disinfectant impregnated in the material sheet contains a quaternary ammonium salt type surfactant in an amount of 0.1% by mass or more and 20% by mass or less as component (A), potassium hydroxide as component (B), (C) ) The composition contains 0.01% by mass or more and 10% by mass or less of an aminocarboxylic acid type chelating agent as a component, and water as a (D) component. 0.5 or more and 13.5 or less, and after impregnating the base sheet with the aqueous disinfectant, the component (A) of the aqueous disinfectant impregnated in the base sheet is passed after 24 hours or more. When the value of the mass ratio (A) / (B) of the component (B) is 0.5 or more and 8 or less, Ri,
A cleaning sheet, wherein the base sheet contains at least one selected from recycled fibers, synthetic fibers, and natural fibers;
(2) Component (A) is an alkyldimethylbenzylammonium chloride having 12 to 16 carbon atoms, didecyldimethylammonium chloride, dioctyldimethylammonium chloride, octyldecyldidecylammonium salt, alkyldimethylethylbenzylammonium chloride, benzethonium chloride, or The cleaning sheet according to the above (1), which comprises octyldecyldimethylammonium chloride.
(3) The base sheet contains 50% or more of at least one kind of regenerated fiber selected from rayon, polynosic, and cupra, and the remainder contains at least one kind selected from synthetic fiber and natural fiber. 1) or the cleaning sheet of (2),
(4) The component (C) is at least one of ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid (NTA), methylglycine diacetate (MGDA), glutamic acid diacetate (GLDA), or a salt thereof. The cleaning sheet according to any one of (1) to (3) above,
(5) The aqueous disinfectant according to the above (1), wherein the aqueous disinfectant further contains at least one selected from the group consisting of an anionic surfactant, a nonionic surfactant and an amphoteric surfactant as the component (E). (4) any of the cleaning sheets,
(6) The cleaning sheet according to any one of the above (1) to (5), wherein the aqueous disinfectant further contains monoethanolamine as a component (F).
(7) After the aqueous sheet is impregnated with the aqueous disinfectant, the component (A) and the component (F) of the aqueous disinfectant impregnated in the substrate sheet are mixed at a mass ratio of 24 hours or more. The cleaning sheet according to the above (6), wherein the cleaning sheet is contained at a ratio of (A) / (F) of 0.1 or more and 10 or less.
(8) The base sheet contains at least 50% of regenerated fibers, and is impregnated with the aqueous disinfectant in an amount of 150 to 350 parts by mass per 100 parts by mass of the fibers constituting the base sheet. The cleaning sheet according to any one of (1) to (7),
It is the gist.

  The cleaning sheet of the present invention has excellent bactericidal properties against bacteria, mold, etc., has an inactivating effect on viruses, can reduce wiping traces after wiping even in a high alkaline area, When the microbial agent is impregnated into the base sheet, there is little decrease in the eradication effect, and it has effects such as antibacterial persistence and antiviral persistence.

  In the aqueous disinfectant to be impregnated in the cleaning sheet of the present invention, the quaternary ammonium salt type surfactant of the component (A) includes dialkyldimethylammonium salt, alkyltrimethylammonium salt, alkyldimethylethylammonium salt, dialkyl Ethyl methyl ammonium salt, dialkyl monomethyl hydroxy ammonium salt, alkyl dimethyl hydroxy ethyl ammonium salt, alkyl benzyl dimethyl ammonium salt, alkyl dipolyoxyethylene methyl ammonium salt, alkyl dipolyoxyethylene methyl ammonium salt, alkyl pyridinium salt, benzethonium salt and the like. No. Here, examples of the alkyl group include an alkyl group having 4 or more and 22 or less carbon atoms, and preferably a straight-chain alkyl group having 6 or more and 18 or less carbon atoms. Specific examples include butyl, hexyl, octyl, decyl, dodecyl, tetradecyl, hexadecyl, heptadecyl, octadecyl, eicosyl, docosyl, and more preferably octyl and decyl. Examples of the salt include a chloride ion, a bromine ion, an alkyl sulfate ion having 1 or 2 carbon atoms, a fatty acid ion having 1 or more and 12 or less carbon atoms, and 1 to 3 or less alkyl groups having 1 to 3 carbon atoms. Benzenesulfonate ions, which may be present, are preferred. The component (A) can be used alone or in combination of two or more. Specifically, octyldecyldimethylammonium chloride, alkyldimethylbenzylammonium chloride, hexadecyltrimethylammonium chloride, didecylmonomethylhydroxyethylammonium chloride, didecylmonomethylhydroxyethylammonium adipate, didecylmonomethylhydroxyethylammonium gluconate, didecyl Monomethylhydroxyethylammonium sulfonate, 1,4-bis (3,3 ′-(1-decylpyridinium) methyloxy) butane dibromide, N, N′-hexamethylenebis (4-carbamoyl-1-decylpyridinium bromide), Alkyldimethylhydroxyethylammonium chloride, alkyltrimethylammonium chloride, Kill dimethylethyl ammonium ethylsulfate, cetyl pyridinium chloride, alkyl dimethyl ethyl benzyl ammonium chloride, decyl isononyl dimethyl ammonium chloride, didecyl methyl polyoxyethylene ammonium propionate, and benzethonium chloride. Among them, from the viewpoint of sterilization and virus inactivating effect, alkyldimethylbenzylammonium chloride, didecyldimethylammonium adipate, decyltrimethylammonium chloride, didecyldimethylammonium chloride, dioctyldimethylammonium chloride, octyldecyldidecylammonium chloride, Alkyldimethylethylbenzylammonium chloride and benzethonium chloride are preferable, and alkyldimethylbenzylammonium chloride having 12 to 16 carbon atoms, didecyldimethylammonium chloride, dioctyldimethylammonium chloride, octyldecyldidecylammonium salt, alkyldimethylethylbenzylammonium chloride, benzethonium Chloride is better Arbitrariness. In particular, dialkyldimethylammonium chloride is preferable because of its excellent bactericidal properties and virus inactivating effect.

  The aqueous disinfectant impregnated in the base sheet preferably contains the component (A) in an amount of 0.00045% by mass or more and 20% by mass or less, and 0.05% by mass or more and 5% by mass or less. Is more preferable, and the content is more preferably 0.1% by mass or more and 4% by mass or less. The content of the component (A) is such that the content of the component (A) of the aqueous disinfectant impregnated in the base sheet is 24 hours or more after the impregnation of the base sheet with the aqueous disinfectant. If the amount is less than 0.00045% by mass, the bactericidal property may decrease. If the amount exceeds 20% by mass, skin may be irritated.

  The cleaning sheet of the present invention is characterized by using an aqueous disinfectant in combination with a specific alkali such as potassium hydroxide as the component (B) and an aminocarboxylic acid type chelating agent as the component (C). In addition to improving the virus inactivating effect, it is possible to reduce wiping traces after wiping even in a high alkaline region having a pH of 10.5 or more and 13.5 or less.

  The aqueous disinfectant impregnated in the base sheet preferably contains the component (B) in an amount of 0.005% by mass or more and 10% by mass or less, and 0.01% by mass or more and 5% by mass or less. Is more preferable, and the content is more preferably 0.05% by mass or more and 2% by mass or less. If the component (B) is less than 0.005% by mass, effects such as sterilization, virus inactivating effects, antibacterial persistence, and antiviral persistence may be reduced. It may affect irritation, corrosion of non-cleaning materials, and discoloration of the non-woven fabric. The content of the component (B) is a value measured by sampling the aqueous disinfectant impregnated in the base sheet after 24 hours or more after impregnating the base sheet with the aqueous disinfectant. . In the aqueous disinfectant for impregnating the base sheet, the value of the mass ratio (A) / (B) of the component (A) and the component (B) may be 0.2 or more and 10 or less. It is more preferably 0.4 or more and 8 or less, and particularly preferably 0.5 or more and 5 or less. When (A) / (B) is 0.2 or more and 10 or less, it is possible to reduce the wiping traces after wiping, remove bacteria, inactivate viruses, and suppress skin irritation. The value of the mass ratio (A) / (B) of the component (A) and the component (B) is determined by impregnating the base sheet with the aqueous disinfectant after 24 hours or more after impregnating the base sheet. It is the value measured by sampling the aqueous disinfectant that is used.

  Aminocarboxylic acid type chelating agents of component (C) in the aqueous disinfectant include ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid (NTA), methylglycine diacetate (MGDA), glutamic acid diacetate (GLDA), and hydroxyethylenediamine Triacetic acid (HEDTA), diethylenetriaminepentaacetic acid (DTPA), triethylenetetraminehexaacetic acid (TTHA), hydroxyethyliminodiacetic acid (HIDA), dihydroxyethylglycine (DHEG), methylglycinediacetic acid (MGDA), aspartic diacetic acid (ASDA), β-alanine diacetate (ADA), serine diacetate (SDA), and alkali metal salts and ammonium salts thereof. The component (C) can be used alone or in combination of two or more. Among them, ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid (NTA), and methylglycinediacetic acid (EDTA) are more excellent in the effect of being able to reduce the wiping trace after wiping by the combination of the detergency and potassium hydroxide. MGDA), glutamic acid diacetate (GLDA) or salts thereof are preferred.

  The aqueous disinfectant impregnated in the base sheet preferably has a component (C) content of 0.005% by mass or more and 10% by mass or less, and 0.01% by mass or more and 5% by mass or less. Is more preferable, and the content is more preferably 0.05% by mass or more and 2% by mass or less. If the content of the component (C) is less than 0.005% by mass, the reduction of wiping traces after wiping, the bactericidal property, the virus inactivating effect, the antibacterial persistence, and the antiviral persistence may be reduced. If it exceeds the mass%, there is a possibility that no further effect can be obtained. The content of the component (C) is a value measured by sampling the aqueous disinfectant impregnated in the base sheet after 24 hours or more after impregnating the base sheet with the aqueous disinfectant. .

  The water as the component (D) in the aqueous disinfectant is not particularly limited, and examples thereof include tap water, well water, ion-exchanged water, and soft water. The component (D) can be used alone or in combination of two or more. Of these, ion-exchanged water or soft water is preferred from the viewpoints of sterilization, virus removal, and feeling of use.

  The aqueous disinfectant impregnated in the base sheet contains water of the component (D) as a solvent, and serves as the balance of the components and other components constituting the cleaning composition. The content of water is preferably 70% by mass or more and 99.99% by mass or less in the whole composition.

  In the cleaning sheet of the present invention, the aqueous disinfectant is impregnated on a substrate sheet capable of retaining a liquid. The pH needs to be 10.5 or more and 13.5 or less in order to exhibit the effect of reducing wiping traces after wiping, but the aqueous disinfectant impregnated in the base sheet is preferably used. The pH is 10.8 or more and 13 or less, more preferably the pH is 11.0 or more and 12.8 or less, and particularly preferably the pH is 11.2 or more and 12.6 or less. If the pH of the aqueous disinfectant impregnated in the base sheet is less than 10.5, the effect on bacteria and viruses is reduced and the cleaning property against dirt is reduced. Corrosion or embrittlement of the impregnated nonwoven fabric occurs. The aqueous disinfectant to be impregnated in the cleaning sheet of the present invention comprises a quaternary ammonium salt type surfactant as the component (A), potassium hydroxide as the component (B), and an aminocarboxylic acid as the component (C). By containing water as the acid-type chelating agent and the component (D), the amount of the quaternary ammonium salt-type surfactant, which is an active ingredient, is absorbed by the fibers of the base sheet when impregnated into the base sheet, and There is little danger of dropping or pH drop, and even when rayon is contained in the base sheet, there is little danger that the amount of active ingredient or pH will drop.

  Examples of the base sheet in the disinfecting sheet of the present invention include nonwoven fabrics, woven fabrics, and net cloths made of recycled fibers, synthetic fibers, natural fibers, and mixed fibers thereof, and those containing recycled fibers are preferable. Regenerated fibers include rayon, polynosic, cupra, lyocell, and acetate, but rayon is preferred from the viewpoint of non-woven fabric drug resistance and less uneven distribution of the drug. When the recycled fiber is used for the base sheet, the base sheet becomes hydrophilic, and the amount of the aqueous disinfectant impregnated can be improved. The ratio of the regenerated fibers in the base sheet is preferably 10% or more, more preferably 50% or more, and even more preferably 70% or more. The base sheet preferably contains at least 50% of regenerated fibers, and the remainder is made of synthetic fibers and / or natural fibers. In the disinfecting sheet of the present invention, the substrate sheet contains at least 50% of regenerated fibers, and the aqueous disinfectant is impregnated with 150 to 350 parts by mass per 100 parts by mass of the fibers constituting the substrate sheet. It is more preferable that it is impregnated at 200 parts by mass or more and 330 parts by mass or less.

  If the aqueous disinfectant used in the cleaning sheet of the present invention further contains at least one selected from the group consisting of an anionic surfactant, a nonionic surfactant and an amphoteric surfactant as the component (E), the cleaning agent may be washed. It is preferable because the property can be improved. Examples of the anionic surfactant include a fatty acid, alkenyl succinic acid, polyoxyalkylene alkyl or alkenyl ether carboxylic acid, alkylol sarcosine, alkyl or alkenyl sulfate, polyoxyalkylene alkyl or alkenyl ether sulfate, amide ether sulfate, and alkylbenzene sulfone. Acid, olefin sulfonic acid, alkane sulfonic acid, alkyl diphenyl ether disulfonic acid, dialkyl sulfosuccinic acid, polyoxyalkylene alkyl ether sulfosuccinic half ester, acyl tauric acid, alkyl monophosphate ester, alkyl triphosphate ester, polyoxyalkylene alkyl ether phosphate Ester, dipolyoxyalkylene alkyl ether phosphate, tripolyoxya Sharp emission alkyl ether phosphate, Tripoli polyoxyalkylene alkyl ether phosphates and alkali metal salts thereof, ammonium salts and the like. These may be used alone or in combination of two or more. Examples of nonionic surfactants include polyoxyalkylene alkyl ether, polyoxyalkylene alkyl phenyl ether, polyoxyalkylene styrenated phenyl ether, polyalkylene glycol monoalkyl fatty acid ester, polyalkylene glycol dialkyl fatty acid ester, polyoxyalkylene glycerin monoalkyl fatty acid Ester, polyoxyalkylene sorbitan monoalkyl fatty acid ester, polyoxyethylene sorbitan trialkyl fatty acid ester, block polymer of polyoxyethylene and polyoxypropylene, random polymer of polyoxyethylene and polyoxypropylene, polyoxyethylene and polyoxy Random polymer with propylene (reverse type), polyoxyethylene and polyoxy Block type ethylene diamine with propylene, block type ethylene diamine with polyoxyethylene and polyoxypropylene (reverse type), sorbitan ester, glyceride (glycerin (mono or di) fatty acid ester), alkyl fatty acid (mono or poly) ester of polyglycerin Glycerin condensed ricinoleate, organic acid monoglyceride, propylene glycol fatty acid ester, sucrose fatty acid ester, alkyl glyceryl ether, alkyl polyglucoside and the like. These may be used alone or in combination of two or more. Examples of the amphoteric surfactant include alkylaminoacetate betaine, alkylamidopropylbetaine, sulfobetaine, alkylamino (mono or di) propionate, imidazolinium betaine, alkylamine oxide, alkylaminoethylglycine, and alkyldi (aminoethyl). Glycine, glycine n- (3-aminopropyl) C10-16 derivative, alkyl polyaminoethyl glycine, alkyl β-alanine, alkyl diethanolamine, polyoxyalkylene alkylamine, oxyethylene addition type surfactant of diamine and the like can be mentioned. These may be used alone or in combination of two or more. The proportion of the component (E) in the aqueous disinfectant is preferably 0.001% by mass or more and 5% by mass or less, more preferably 0.01% by mass or more and 2% by mass in the disinfectant impregnated in the base sheet. % By mass or less is more preferable.

  The aqueous disinfectant used for the cleaning sheet of the present invention may further contain monoethanolamine as the component (F). When monoethanolamine is contained, not only can it maintain a stable pH (buffer action) even in a highly alkaline region, it can further improve the effect of reducing wiping traces after wiping, and it also improves sterilization properties and virus inactivation effect can do.

  The component (F) is preferably 0.005% by mass or more and 10% by mass or less, and more preferably 0.01% by mass or more and 5% by mass or less in the aqueous disinfectant impregnated in the base sheet. More preferably, the content is 0.05% by mass or more and 2% by mass or less. When the proportion of the component (F) in the aqueous disinfectant is less than 0.005% by mass, a stable effect of maintaining pH, an effect of reducing wiping marks after wiping, a sufficient effect of disinfecting properties, and an effect of inactivating viruses are obtained. It may not be obtained, and if it exceeds 10% by mass, skin irritation may be affected. The content of the component (F) is a value measured by sampling the aqueous disinfectant impregnated in the base sheet after the aqueous disinfectant has been impregnated in the base sheet and having passed for 24 hours or more. . In addition, the aqueous disinfectant impregnated in the base sheet has an effect of reducing wiping marks after wiping, disinfecting property, disinfecting property against spores, inactivating virus, and preventing discoloration of nonwoven fabric. The value of the mass ratio (A) / (F) of the component (A) to the component (F) is preferably 0.1 or more and 20 or less, more preferably 0.3 or more and 5 or less. , 0.5 or more and 3 or less. The value of the mass ratio (A) / (F) of the component (A) and the component (F) is determined by impregnating the base sheet with the aqueous disinfectant after 24 hours or more after impregnating the base sheet. It is the value measured by sampling the aqueous disinfectant that is used.

  The aqueous disinfectant used in the cleaning sheet of the present invention may further contain components commonly used in the art. Such components include, for example, organic solvents, fragrances, dyes, and the like. The proportion in these aqueous disinfectants is preferably 0.001% by mass or more and 10% by mass or less, more preferably 0.05% by mass or more and 5% by mass or less.

  Examples of the organic solvent include methanol, ethanol, 1-propanol, 2-propanol, acetone and the like. These may be used alone or in combination of two or more. The organic solvent is preferably contained in the aqueous disinfectant in an amount of 0.001% by mass or more and 5% by mass or less, and more preferably 0.01% by mass or more and 3% by mass or less, from the viewpoint of improving the liquid stability in a solution state. Is more preferable.

As the above-mentioned fragrance, those contained in conventionally known natural products having various fragrances can be used without particular limitation.For example, natural fragrances extracted from natural products such as peppermint oil, and synthetic products such as limonene are used. Synthetic fragrances, fragrances obtained by mixing two or more kinds of known fragrances in an appropriate ratio, and the like are included.
For example, natural flavors include anise oil, basil oil, bergamot oil, cedar oil, clove oil, coriander oil, eucalyptus oil, fennel oil, galbanum oil, geranium oil, jasmine absolute, lavandin oil, lavender oil, lemongrass oil, Lemon oil, lavender spike oil, neroli oil, oak moss absolute, patchouli oil, petit gren oil, pine oil, rose oil, rosemary oil, clary sage oil, sandalwood oil, thyme oil, tonka absolute, tuberose absolute, vetiver oil, iran Iran oil, peppermint oil, camphor oil, aromatic oil, perilla oil, spearmint oil, star anise oil, lime oil, cocoa oil, turpentine oil, nutmeg oil, citronella oil, boad rose oil, cananga oil, cardamom oil, cassia oil, Range oil, mandarin oil, tangerine oil, bay oil, elemi oil, hiba oil, hinoki oil, grapefruit oil, citron oil, and the like.

  Examples of the synthetic fragrance include hydrocarbons, alcohols, aldehydes, ketones, lactones or oxides, ethers, esters and the like. Examples of the hydrocarbons include α-pinene, limonene, camphene, p-cymene, Fenchen, ocimene and guaien. Examples of alcohols include linalool, geraniol, citronellol, nerol, menthol, borneol, benzyl alcohol, anis alcohol, nerolidol, eugenol, α-phenylethyl alcohol, β-phenylethyl alcohol, rhinol, ambrinol, myrcenol, tetrahydrolinalool, Terpineol, cedrol, 1-octanol, 3-octanol, 9-decenol, 10-undecenol, dihydrocarbeol, prenol, ethyl linalool, 3-heptanol, benzyl eugenol, 2-ethylhexanol, 3-hexenol, 2,4-dimethyl -3-cyclohexene-1-methanol, 4-isopropylcyclohexanol, P-isopropylcyclohexenemethanol, 1-nona , 2-nonanol, P-isopropylcyclohexanol, 2-methyl-3-buten-2-ol, 2-hexenol, 1-nonen-3-ol, 3-methyl-1-ventanol, 2,6-dimethyl -Heptanol and 3,4,5,6,6-pentamethyl-2-heptanol and the like. Examples of the aldehydes include n-butyraldehyde, isobutyraldehyde, hexylaldehyde, heptylaldehyde, n-nonylaldehyde, nonadienal, citral, citronellal, benzaldehyde, cinamic aldehyde, heliotropin, crocodile, tripiral, 2-dodecenal, and 2,5. , 6-Trimethyl-4-heptanal, trimethylundecenal, 2-decenal, p-tolylaldehyde, acetaldehyde diethyl acetal, n-octanal, n-decanal, p-isopropylphenylacetaldehyde, octanal dimethyl acetal, n-nonanal, Undecanal, 10-undecenal, phenylpropionaldehyde, 3-hexenal, 2-undecenal and p-methylhydratro Aldehyde, and the like. Examples of ketones include methyl amyl ketone, methyl nonyl ketone, diacetyl, acetyl propionyl, acetyl butyryl, carboxyl, menthone, camphor, acetophenone, p-methyl acetophenone, ionone, dihydrocarbon, and 2-undecanone. Lactones or oxides include amylbutyrolactone, ethyl methylphenylglycidate, γ-nonyllactone, coumarin, cineol, jasmine lactone, methyl r-decalactone, 2,2,6-trimethyl-6-vinyltetrahydropyran and 5- Isoproperol-2-methyl-2-vinyltetrahydrofuran and the like. Examples of ethers include 1,8-cineole, rose oxide, cedrol methyl ether (cedrum bar), p-cresyl methyl ether, isoamylphenylethyl ether, 4-phenyl-2,4,6-trimethyl-1,3-dioxane , Anethole and the like. As esters, methyl formate, isopropyl formate, linalool formate, ethyl acetate, octyl acetate, menthyl acetate, benzyl acetate, cinnamyl acetate, butyl propionate, isoamyl acetate, isopropyl isobutyrate, granyl isovalerate, Allyl caproate, butyl heptylate, octyl caprylate, methyl heptinecarboxylate, ethyl perahagonate, methyl octynecarboxylate, isoacylcaprate, methyl laurate, ethyl myristate, ethyl benzoate, benzyl benzoate, methyl phenylacetate Butyl acetate, methyl cinnamate, cinnamyl cinnamate, methyl salicylate, ethyl anisate, methyl anthranilate, ethyl pyruvate, ethyl α-butyl butyrate, vinegar Decyl and propyl formate and the like.

Examples of the dye include a natural dye, a synthetic dye, and a mixture of two or more of these. Specific examples of the natural dyes include red cabbage dye (purple red), red radish dye (red orange to reddish purple), purple yam dye (purple red), beet red (red), and alkanet dye ( Red to reddish purple), cochineal dye (yellow orange to purple), lac dye (red orange to purple), safflower red dye (red), madder dye (yellow orange to reddish purple), gardenia red dye (red), red beige (Red), pepper dye (yellow to red-orange), annatto dye (yellow to red-orange), gardenia yellow (yellow), safflower yellow (yellow), turmeric dye (yellow), marigold dye (yellow), caramel Pigment (dark brown to black), Kouryang pigment (red brown to dark brown), onion pigment (brown), cyanat pigment (brown), pecan nut pigment (brown), chicory pigment (red brown to brown), cacao pigment (red ~ Brown), chlorophyll (green), gardenia blue pigment (blue), and the like spirulina pigment (blue).
Specific examples of the synthetic dyes include Red No. 1, Red No. 2, Red No. 3, Red No. 4, Red No. 5, Red No. 101, Red No. 102, Red No. 103, Red No. 104, Red No. No. 105, Red No. 106, Orange No. 1, Orange No. 2, Yellow No. 1, Yellow No. 2, Yellow No. 3, Yellow No. 4, Yellow No. 5, Green No. 1, Green No. 2, Green No. 3, Blue No. 1 , Blue No. 2, Purple No. 1, and edible mixed dyes.

  The cleaning sheet of the present invention is characterized in that the impregnated aqueous disinfectant has a strong disinfecting property and a virus inactivating effect and is excellent in disinfecting and removing viruses against bacteria and viruses, so that contamination by bacteria and viruses can be prevented. -It is useful for disinfection and virus removal in a wide range of fields where contamination is a problem, mainly in the medical, food, brewing, and agricultural fields. In particular, it can be suitably used for sterilization of hard surfaces in the medical field.

  The cleaning sheet of the present invention can be applied in various applications, for example, surface disinfection except for the surface of human skin, disinfection of equipment, or for disinfecting and removing viruses around toilets and beds, for mold prevention, and virus inactivation. It is suitable for use. The cleaning sheet of the present invention can be formed into a form in which a plurality of sheets are stacked, a form in which a long sheet is rolled or folded, or the like.

  Hereinafter, the present invention will be described specifically with reference to Examples and Comparative Examples, but the present invention is not limited thereto. The components used in the Examples and Comparative Examples are shown below. In addition, EO is an abbreviation for ethylene oxide and PO is an abbreviation for propylene oxide, and the numbers thereafter represent the average number of added moles of EO and PO, respectively. In addition, the numerical value of the combination of each component in the examples and comparative examples in the table represents the mass% of the pure content. The notation of the alkyl group in each component indicates, for example, in the case of alkyl (C12 to C16), a mixture having an alkyl group having 12 or more and 16 or less carbon atoms.

(A) Component A-1: Octyldecyldimethylammonium chloride A-2: Dioctyldimethylammonium chloride A-3: Didecyldimethylammonium chloride A-4: Alkyl (C12-16) dimethylbenzylammonium chloride (A ') component [ Comparative component of component (A)]
A'-1: laurylamine

(B) Component B-1: Potassium hydroxide (B ') component [Comparison component of (B) component]
B'-1: sodium hydroxide

(C) Component C-1: tetrasodium ethylenediaminetetraacetic acid salt (EDTA-4Na)
C-2: nitrilotriacetic acid trisodium salt (NTA-3Na)
C-3: Methylglycine diacetate trisodium salt (MGDA-3Na)
C-4: Glutamic acid diacetate tetrasodium salt (GLDA-4Na)

(D) Component D-1: ion-exchanged water

(E) Component E-1: Nonionic surfactant 1 [polyoxyethylene (EO: 6.5 mol) alkyl (C9-11) ether]
E-2: Nonionic surfactant 2 [polyoxyethylene (EO: 25 mol) alkyl (tallow fat) ether]
E-3: octyl dimethyl amine oxide E-4: dodecyl dimethyl amine oxide

(F) Component F-1: monoethanolamine

Examples 1 to 64, Comparative Examples 1 to 7
An aqueous disinfectant was prepared based on the formulations shown in Tables 1 to 7. The aqueous disinfectant was impregnated with the aqueous disinfectant for 24 hours at 300 parts by mass per 100 parts by mass of the base sheet, and the disinfectant was sufficiently spread on the base sheet. To make a cleaning sheet. The cleaning sheet is tightened with a force of 10 N · cm for 10 minutes using a vice, the pH of the squeezed solution (hereinafter referred to as “extraction liquid”), the amount of the component (A) in the extraction liquid, the cleaning sheet. Reduction of wiping marks, disinfection, virus inactivation, skin irritation, antibacterial persistence, antiviral persistence, corrosiveness test for material to be cleaned, discoloration test of nonwoven fabric with disinfectant, detergency The test was performed. In addition, the properties of the feeling of use of the cleaning sheet with respect to the aqueous disinfectant were evaluated. The results are shown in Tables 1 to 7.

Measurement method of pH of extracted liquid <Calibration of pH meter>
A pH measuring composite electrode (manufactured by HORIBA; glass rubbing sleeve type) is connected to a pH meter (manufactured by HORIBA; pH / ion meter F-23), and the power is turned on. A saturated aqueous potassium chloride solution (3.33 mol / L) was used as the pH electrode internal solution. Next, a pH 4.01 standard solution (phthalate standard solution), a pH 6.86 standard solution (neutral phosphate standard solution), and a pH 9.18 standard solution (borate standard solution) were filled in 100 mL beakers, respectively. Immersed in a thermostat at 25 ° C. for 30 minutes. The electrode for pH measurement was immersed in the standard solution adjusted to a constant temperature for 3 minutes, and the calibration operation was performed in the order of pH 6.86, pH 9.18, and pH 4.01.
<PH measurement>
The electrode for pH measurement was immersed in 100 mL of the extracted liquid adjusted to a constant temperature of 25 ° C. in a constant temperature bath for 3 minutes, and the pH was measured.

Method for measuring the amount of component (A) in the extract (amount of cationic surfactant) Take 8 mL of the extract in a beaker, and add 1 mL of 0.25 M sodium acetate buffer at pH 5.7 to the extract, 6 × 10 ^−. 1 mL of a ⁴ M Chromazurol S solution was sequentially added, and the mixture was titrated with a 2.0 mol / L aqueous solution of sodium lauryl sulfate while stirring with a magnetic stirrer to determine the amount of the component (A) in the extracted liquid. The end point of the titration was visually determined that the solution changed color from purple to orange.

* 1: Test to reduce wiping traces with a cleaning sheet A glass plate of 15 cm x 15 cm was prepared, and the surface of the glass plate was wiped up and down five times and left and right five times with each cleaning sheet shown in Tables 1 to 7. went. Thereafter, the glass plate was dried at room temperature for 2 hours, and the remaining wiping marks generated on the surface of the glass plate were visually evaluated.
Evaluation criteria:
：: No trace of wiping remains.
〇: Almost no trace of wiping remains.
Δ: Slight wrinkle marks left, but no problem.
X: The remaining trace after wiping is worrisome.
△, 〇, and ◎ were judged to be practical.

* 2: Eradication test (spore bacterium)
Test method:
The test strain was spread on an SCD agar medium (Nissui Pharmaceutical Co., Ltd.), cultured at 37 ° C., and after culturing, it was confirmed by microscopic observation that spores had been sufficiently formed. 10 mL of sterilized pure water was put on the plate medium, the colonies were scraped, and the suspension was collected. The collected suspension was subjected to centrifugal washing three times at 10,000 rpm at 4 ° C. for 15 minutes, and after centrifugation, an appropriate amount of sterilized pure water was added thereto, and 2.0 × 10 ^{8 to} 9.0 × 10 ^8. The number of bacteria was adjusted to about CFU / mL, and heat-treated at 80 ° C. for 15 minutes in a water bath to obtain a spore bacterium solution.
To 10 mL of each squeezed solution, 0.1 mL of the test spore bacterium solution was added, and the mixture was brought into contact at 25 ° C. for 15 minutes.
Bacillus subtilis NBRC3134 (10 ⁸ CFU / mL level) and Clostridium difficile ATCC 9689 (10 ⁸ CFU / mL level) were used as spores.
This 1 mL was pulverized and cultured on an SCD agar medium to confirm the viable cell count, and evaluated according to the following criteria.
Evaluation criteria:
1 point: The number of bacteria whose log reduction of the test bacteria is 3 or more decreases 2 points: The number of bacteria of the test bacteria whose log reduction is 2 or more and less than 3 3 points: The number of bacteria whose log reduction of the test bacteria is less than 2 As a decrease, the decrease in the number of bacteria was evaluated by a score for each of the above bacterial species, an average value of the scores of the decrease in the number of bacteria was obtained, and the eradication property was evaluated according to the following criteria.
A: Average value is 1.0 point or more and less than 1.5 points.
：: The average value is 1.5 or more and less than 2.0 points.
Δ: Average value is 2.0 points or more and less than 2.5 points.
X: The average value is 2.5 points or more.
△, 、, and ◎ were judged to be practical.

* 3: Virus inactivation test Test method:
0.9 mL of the squeezed solution and 0.1 mL of the virus solution adjusted to 10 ⁸ TCID50 / mL were added to a test tube, mixed with a mixer, and allowed to act at 25 ° C. for 10 minutes. After the action, 0.1 mL was sampled, added to 9.9 mL of an action stop solution (a cell growth solution containing 2% sodium thiosulfate, 0.2% lecithin and 1.5% polysorbate 80) and diluted 100-fold. The action of the aqueous disinfectant (squeeze) on the virus was stopped. This was used for the measurement of infectious titer as a stock solution for measuring the viral infectious titer. Similarly, a test using phosphate buffered saline (hereinafter sometimes abbreviated as PBS) instead of the squeezed solution was performed and used as a control. Phosphate buffered saline is a mixture of 4 g of sodium chloride 8 g, potassium chloride 0.2 g, disodium hydrogen phosphate 1.44 g, potassium dihydrogen phosphate 0.24 g, and 900 mL with ultrapure water. After dissolution, the pH is adjusted to 7.4 with hydrochloric acid. After raising the volume to 1 L, sterilize with an autoclave. Feline calicivirus, mouse norovirus, hepatitis B virus, hepatitis C virus, adenovirus, AIDS virus, and influenza virus were used as viruses.
The sample solution for viral infectivity titration was serially diluted 10-fold with PBS, and then Dulbecco's modified Eagle's Medium (DMEM) containing 50 μL of the sample solution for infectious titer and diluted virus solution and 5% fetal bovine serum (FBS) was added. ) Were seeded in a 96-well plate. Thereafter, the cells were cultured in a carbon dioxide incubator at 37 ° C. and 5% CO ₂ for 4 days.
After the culture, the presence or absence of CPE (cytopathic effect) due to virus growth was observed under an inverted microscope, and the virus infection titer (TCID50 / mL) was determined using the Reed-Muench method, and evaluated according to the following criteria.
Evaluation criteria:
1 point: Log reduction of virus infection titer is 5 or more 2 points: Log reduction of virus infection titer is 4 or more and less than 5 3 points: Log reduction of virus infection titer is 3 or more and less than 4 4 points : The reduction of the virus infectivity for each of the above viruses was evaluated by a score, assuming that the Log reduction of the virus infectivity was less than 3, and the average value was obtained.
A: Average value is 1.0 point or more and less than 1.5 points.
〇: Average value is 1.5 points or more and less than 2.5 points.
Δ: The average value is 2.5 points or more and less than 3.5 points.
X: The average value is 3.5 or more.
△, 、, and ◎ were judged to be practical.

* 4: Test on skin irritation Take out one cleaning sheet shown in Tables 1 to 7 and cut out 1cm square, and use adhesive tape inside the elbow of the subject (adult randomly selected). Immediately after the application and peeling after 24 hours, the condition of the skin was visually checked to evaluate the skin irritation.
Evaluation criteria:
A: Erythema and edema are not observed at all.
〇: Erythema and edema are hardly observed.
Δ: Slight reddish erythema and mild edema are observed.
X: Strong reddish erythema and severe edema are observed.
△, 、, and ◎ were judged to be practical.

* 5: Antibacterial durability test A stainless steel plate of 20 mm x 20 mm was prepared, and each of the cleaning sheets shown in Tables 1 to 7 was wiped up and down 5 times left and right 5 times, and then in an incubator set at 25 ° C for a predetermined time ( (1 hour, 12 hours, 24 hours, 72 hours). An untreated stainless plate was also prepared as a control. Each test panel which had been allowed to stand for a predetermined time was placed in a sterilized plastic bottle, and various bacterial liquids (bacterium: Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Alcaligenes faecalis, Serratia genius, Serratia genius germ), which were prepared by a sterilization test, were tested. 0.2 mL was inoculated and applied evenly over the entire panel surface. After naturally drying each test panel at 25 ° C. for 2 hours, 20 mL of SCDLP medium for bacteria and 20 mL of GPLP liquid medium for mold were added, put in a stomacher bag, rubbed by hand 60 times to wash out the bacteria. The washed test solution was cultured on an SCD agar medium for bacteria and a PDA medium for mold, and the number of bacteria (cfu / mL) was determined.
Evaluation criteria:
1 point: Up to 72 hours of standing time, the common logarithm of the number of bacteria is smaller than the control by 3 or more.
2: The common logarithm of the number of bacteria is 3 or more smaller than the control until the standing time is 24 hours.
3 points: The common logarithmic value of the number of bacteria is 3 or more smaller than the control until the standing time is 12 hours.
4 points: Up to 1 hour of standing time, the common logarithm of the number of bacteria is smaller than the control by 3 or more.
The antimicrobial durability was evaluated by a score.
For bacteria, the average value of the antibacterial persistence was determined for five types of bacteria, and the antibacterial persistence effect was evaluated according to the following criteria.
A: Average value is 1.0 point or more and less than 1.5 points.
〇: Average value is 1.5 points or more and less than 2.5 points.
Δ: The average value is 2.5 points or more and less than 3.5 points.
X: The average value is 3.5 or more.
For mold, an average value of one kind of mold having antibacterial sustainability was determined and evaluated according to the following criteria.
A: Average value is 1.0 point or more and less than 1.5 points.
〇: Average value is 1.5 points or more and less than 2.5 points.
Δ: The average value is 2.5 points or more and less than 3.5 points.
X: The average value is 3.5 or more.
Both 抗菌, 、, and ◎ were judged to be practical for both the antibacterial persistence against bacteria and the antibacterial persistence against mold.

* 6: Antiviral persistence test A 20 mm x 20 mm stainless steel plate was prepared, and the surface of the stainless steel plate was wiped up and down 5 times and left and right 5 times with each of the cleaning sheets shown in Tables 1 to 7, and set at 25 ° C. It is left still for a predetermined time (1 hour, 12 hours, 24 hours, 72 hours) in the incubator. An untreated stainless plate was also prepared as a control. Each stainless plate which had been allowed to stand for a predetermined time was placed in a sterilized plastic bottle, and 0.2 mL of a virus solution (a feline calicivirus, a mouse norovirus, an adenovirus, an influenza virus) was inoculated and applied evenly over the entire panel surface. After naturally drying each stainless plate at 25 ° C. for 2 hours, 20 mL of SCDLP medium was added, put in a stomacher bag, rubbed by hand 60 times to wash out the virus. After preparing a dilution series of the washed test solution by a 10-fold dilution method using a cell culture medium, host cells corresponding to each virus (feline calicivirus: Crandekk-Reese feline kidney cell, mouse norovirus: Mouse monocyte / macrophage) cell line RAW264, adenovirus: Hela cell, influenza virus: Madin-Darby canine kidney cell).
After a certain period of time, the presence or absence of virus infection was observed, and the virus infection titer (TCID50 / mL) was determined.
Evaluation criteria:
1 point: Up to 72 hours of standing time, the common logarithmic value of the virus infection titer is 3 or more smaller than that of the control.
2: The logarithmic value of the virus infection titer is 3 or more smaller than that of the control until the standing time is 24 hours.
3 points: Up to 12 hours of standing, the logarithm of the virus infection titer is 3 or more smaller than that of the control.
4 points: Up to 1 hour of standing time, the common logarithmic value of the virus infectivity is 3 or more smaller than that of the control.
The above-mentioned antiviral persistence was evaluated by a score, the average value of the antiviral persistence for each virus was obtained, and the antiviral persistence effect was evaluated according to the following criteria.
A: Average value is 1.0 point or more and less than 1.5 points.
〇: Average value is 1.5 points or more and less than 2.5 points.
Δ: The average value is 2.5 points or more and less than 3.5 points.
X: The average value is 3.5 or more.
△, 、, and ◎ were judged to be practical.

* 7: Evaluation test method for corrosiveness of material to be cleaned Test method:
One stainless steel plate (SUS304) cut into a size of 3 cm × 5 cm was immersed in the squeezed liquid of each cleaning sheet shown in Tables 1 to 7, and stored at 25 ° C. for 48 hours. After rinsing the plate with ion exchanged water and drying at room temperature for 24 hours, the degree of corrosion was visually evaluated.
Evaluation criteria:
：: No discoloration, rust, deterioration, etc. were observed.
：: Almost no discoloration, rust, deterioration, etc. are observed.
Δ: Discoloration, rust, deterioration, etc. are seen in a part, but there is no problem.
X: Discoloration, rust, deterioration, etc. are seen throughout. △, 、, and ◎ were judged to be practical.

* 8: Evaluation test for discoloration of nonwoven fabric by disinfectant Test method:
After ten weeks of each cleaning sheet (200 mm × 250 mm) shown in Tables 1 to 7 were stored at 40 ° C. for one week, changes in the appearance of the cleaning sheet were visually observed.
Evaluation criteria:
A: No discoloration or deterioration occurred.
：: Light discoloration and slight deterioration hardly occurred.
Δ: Dark discoloration or strong deterioration slightly occurred, but no problem.
X: Dark discoloration or strong deterioration occurred as a whole.
△, 、, and ◎ were judged to be practical.

* 9: Detergency test Test method:
A test piece was prepared by attaching and drying a pseudo soil obtained by mixing tallow: soybean oil: chloroform at a ratio of 1: 1: 5 to a SUS304 test plate (15 × 50 mm) whose mass was measured, and measuring the mass. The test piece was fixed on a flat surface, and 50 g of each cleaning sheet shown in Tables 1 to 7 was taken out and placed on the test piece in a state where it was folded twice, and a weight having a mass of 300 g was placed thereon. In this state, the cleaning sheet was swung up and down five times at intervals of once per second to wipe it. Thereafter, the test piece was rinsed with ion-exchanged water, allowed to dry naturally, and then weighed. The cleaning rate was calculated from the following equation based on the change in the mass of the test piece before and after wiping, and was shown on the following scale.
(Equation 1)
Cleaning rate = (ST) / (SU) × 100
S: Weight of test piece before wiping T: Weight of test piece after wiping U: Weight evaluation standard of stainless steel plate:
：: Cleaning rate of 70% or more and 100% or less Δ: Cleaning rate of 30% or more and less than 70% ×: Cleaning rate of less than 30%, and Δ and ○ were judged to be practical.

* 10: Evaluation test for feeling of use Test method:
Using ten cleaning sheets (200 mm × 250 mm) shown in Tables 1 to 7, one non-woven fabric impregnated with the chemical was taken out, and a clean stainless steel surface was moved up and down 5 times in 5 directions up and down about 30 cm square. The wiping was performed, and the feeling of use was confirmed by a sensory test from the viewpoints of foaming, stickiness, wateriness, stiffness and wetness. In addition, panelists were randomly selected, and n = 10 for each sample. Statistical processing was performed to analyze the evaluation results, and the item with the highest evaluation was adopted as the evaluation result.
Evaluation criteria:
：: There is no foaming, stickiness, wateriness, stiffness, moderate moisture, and good usability.
Δ: Slight foaming, stickiness, wateriness, stiffness, or no moderate moisture.
X: Very strong foaming, stickiness, wateriness, and stiffness, or poor usability with little moisture.
△ and ○ were judged to be practical.

Claims (8)

In a cleaning sheet impregnated with an aqueous disinfectant for a substrate sheet capable of holding a liquid, after impregnating the aqueous disinfectant into the substrate sheet, after 24 hours or more, the substrate sheet 0.1% by mass or more and 20% by mass or less of a quaternary ammonium salt type surfactant as the component (A) of the impregnated aqueous disinfectant, potassium hydroxide as the component (B), and component (C) as the component. The aminocarboxylic acid-type chelating agent contains 0.01% by mass or more and 10% by mass or less and water as a component (D), and the pH of the aqueous disinfectant impregnated in the base sheet is 10.5 or more. , 13.5 or less, after impregnating the base sheet with the aqueous disinfectant, the components (A) and (B) of the aqueous disinfectant impregnated on the base sheet after 24 hours or more have passed. Has a value of mass ratio (A) / (B) of 0.5 or more and 8 or less,
A cleaning sheet, wherein the base sheet includes at least one selected from recycled fibers, synthetic fibers, and natural fibers.   The component (A) is an alkyldimethylbenzylammonium chloride having 12 to 16 carbon atoms, didecyldimethylammonium chloride, dioctyldimethylammonium chloride, octyldecyldidecylammonium salt, alkyldimethylethylbenzylammonium chloride, benzethonium chloride, or octyldecyldimethyl. The cleaning sheet according to claim 1, further comprising ammonium chloride.   The said base sheet contains 50% or more of at least one kind of regenerated fiber selected from rayon, polynosic, cupra, and the rest contains at least one kind selected from synthetic fibers and natural fibers. The cleaning sheet according to any one of the above.   The component (C) is at least one of ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid (NTA), methylglycine diacetate (MGDA), glutamic acid diacetate (GLDA), or a salt thereof. The cleaning sheet according to claim 1.   The aqueous disinfectant further comprises at least one selected from the group consisting of an anionic surfactant, a nonionic surfactant, and an amphoteric surfactant as the component (E). A cleaning sheet according to claim 1.   The cleaning sheet according to any one of claims 1 to 5, wherein the aqueous disinfectant further contains monoethanolamine as the component (F). After 24 hours or more have passed since the aqueous sheet was impregnated with the aqueous disinfectant, the components (A) and (F) of the aqueous disinfectant impregnated in the substrate sheet were added at a mass ratio of (A) The cleaning sheet according to claim 6, wherein the cleaning sheet is contained at a ratio of / (F) of 0.1 or more and 10 or less.   The base sheet contains at least 50% of regenerated fibers, and is impregnated with the aqueous disinfectant in an amount of 150 parts by mass or more and 350 parts by mass or less per 100 parts by mass of the fibers constituting the substrate sheet. The cleaning sheet according to any one of 1 to 7.