JP6133070B2 - Cryogenic storage system - Google Patents

Description

  The present invention relates to a cryogenic storage system comprising a cryogenic storage chamber for storing a plurality of containers containing samples, and a container accommodating means configured to be movable in an upper space of the cryogenic storage chamber and transferring the containers. Drug discovery, a cryogenic storage system used for cryogenic storage of drug discovery samples used in the process of drug discovery and design in medicine, biotechnology and pharmacy.

In recent years, in basic research or applied research such as chemistry, biochemistry, biology, and pharmaceuticals, a large amount of biological samples, clinical samples, chemical compounds, and the like have been stored for examinations and the like.
For example, in the drug discovery research process, in order to investigate bioactivity, etc., it is necessary to handle a large number of samples in a very small amount for a variety of examinations and experiments, and they are contained in containers such as micro (test) tubes. A technique for storing a large amount of samples in a stable environment at a very low temperature and taking out any sample quickly is indispensable.

  Such a cryogenic storage system for storing a sample to be stored at a low temperature in a cryogenic storage chamber and taking out a designated container from the cryogenic storage chamber as necessary is well known. A plurality of storage plates are held in a storage rack in the vertical direction and stored in a low temperature storage chamber. When necessary, the target storage plate is automatically taken out and specified from the storage plate. A cryogenic storage system for picking a container is known (see, for example, Patent Document 1).

  This known low-temperature storage system (100) includes a storage rack (104) for storing a plurality of storage plates (203) for holding a plurality of containers (201) in the vertical direction, and a low-temperature storage for storing a plurality of the storage racks (104). A chamber (105), a work chamber (106) provided adjacent to the low temperature storage chamber (105), a storage plate (203) provided in the work chamber (106) and a storage rack (104) And a plate conveying mechanism (110) for taking in and out.

The work chamber (106) is provided with a pick-up mechanism (120) capable of individually taking out the containers (201) from the storage plate (203), and is provided adjacent to the work chamber (106). Is provided.
The plate transport mechanism (110) includes storage rack moving means (111) for individually moving the storage rack (104) into and out of the working chamber (106) from the low temperature storage chamber (105), and storage plates (203). ) And a storage plate moving means (112) for taking in and out individually, and is configured to be movable in the working chamber.

Thus, the storage plate (203) holding the container (201) to be taken out is transported from the low temperature storage chamber (105) to the pickup mechanism (120), and only the container to be taken out is individually taken out by the pickup mechanism (120). It is possible to carry out from the loading / unloading room (108).
In addition, the code | symbol in the parenthesis of each said component is a code | symbol described in patent document 1. FIG.

JP 2012-56730 A

In a known low-temperature storage system as shown in Patent Document 1, a plurality of containers supported by a storage plate are transported from a low-temperature storage chamber to a work chamber, and a plurality of containers supported by the storage plate by a picking mechanism in the work chamber. After the designated container is extracted from the container, the remaining container is stored again in the cold storage room.
For this reason, containers other than the designated container that should be stored in the low temperature storage chamber again will be placed in their atmosphere during transportation and during the extraction operation by the picking mechanism in the work room. As the temperature rose, the sample could be altered and damaged.
In addition, if a large amount of dew condensation occurs in the container during the extraction operation by the picking mechanism and is stored again in the low temperature storage chamber as it is, it may freeze and the storage plate and the container will adhere, making it difficult to pick the next container. In order to prevent this, it was necessary to strongly dehumidify the atmosphere in the carry-out area.

In order to reduce these problems, it is conceivable to maintain the ambient temperature in the upper space of the low temperature storage room or the working room at a low temperature equivalent to that of the low temperature storage room.
However, it is necessary to use special equipment in order to configure such transport means and picking mechanisms that operate at low temperatures. Such special equipment is difficult to obtain, expensive, and normal equipment. Since the operation is slower than the crisis, problems such as manufacturing, cost, and operation speed are large.
In addition, it is necessary to reinforce the air conditioning equipment of the entire cryogenic storage system for placing the space above the cold storage room and the work room in a low temperature environment, which increases the operating cost and also performs maintenance work immediately after operation at extremely low temperatures. Since it is necessary to carry out with respect to equipment, it places a heavy burden on the operator, and there are also large operational problems.

  The present invention solves these problems, does not increase the temperature of the container during the extraction operation, prevents the sample contained in the container from degeneration and condensation on the container, and special equipment. An object of the present invention is to provide a low-temperature storage system that can operate at high speed without requiring any kind, reduces the cost of manufacturing and operation, and is easy to operate.

  The invention according to claim 1 includes a low-temperature storage chamber that stores a plurality of containers that store samples, and container storage means that can move in an upper space of the low-temperature storage chamber and can hold the containers. In the low-temperature storage system, the container storage means includes a low-temperature storage tank that opens upward and stores the container, and a refrigerant pipe that cools the inside of the low-temperature storage tank. is there.

In addition to the configuration of the low temperature storage system according to claim 1, the invention according to claim 2 is configured such that the low temperature storage tank is partitioned into two or more storage areas by at least one partition wall, and the refrigerant pipe is The problem is solved by being provided along the inner wall of the low temperature storage tank and the partition wall.
In addition to the structure of the low temperature storage system according to claim 2, the invention according to claim 3 solves the above-mentioned problem by the fact that the inner wall and the partition wall of the low temperature storage tank are made of metal. .
In addition to the configuration of the low-temperature storage system according to claim 2 or claim 3, the invention according to claim 4 is provided with a partition plate inside the storage region, and the partition plate and the inside of the low-temperature storage tank A cold air circulation space is formed between the wall or the partition wall, and the refrigerant pipe is provided in the cold air circulation space.

The invention according to claim 5 solves the above problems by providing a circulation fan above the cold air circulation space in addition to the configuration of the low-temperature storage system according to claim 4.
In the invention according to claim 6, in addition to the configuration of the low temperature storage system according to any one of claims 2 to 5, the low temperature storage tank includes an upper portion that closes a part of an opening above the storage area. The problem is solved by providing the wall.
The invention according to claim 7 solves the above problem by providing the refrigerant pipe along the lower surface of the upper wall in addition to the configuration of the low-temperature storage system according to claim 6.
According to an eighth aspect of the present invention, in addition to the configuration of the low-temperature storage system according to any one of the second to seventh aspects, the refrigerant pipe is provided so as to come into contact with the inner wall and the partition wall of the low-temperature storage tank. As a result, the above-described problems are solved.
The invention according to claim 9 solves the above-described problem by the fact that the refrigerant pipe has a heat radiation fin in addition to the configuration of the low-temperature storage system according to any one of claims 2 to 8.

In addition to the configuration of the low temperature storage system according to any one of claims 1 to 9, the invention according to claim 10 is provided with a heat insulating wall on the outer side of the inner wall of the low temperature storage tank, and the heat insulating wall The above-mentioned problem is solved by providing a cooling means for supplying the refrigerant to the refrigerant pipe outside the pipe.
According to the eleventh aspect of the present invention, in addition to the configuration of the low-temperature storage system according to any one of the first to tenth aspects, the low-temperature storage tank is provided with an opening / closing lid capable of closing and opening an upper opening. Thus, the above-mentioned problem is solved.
In addition to the configuration of the low temperature storage system according to any one of claims 1 to 11, the low temperature storage chamber is configured to store a plurality of storage racks so that they can be taken in and out from above. The storage rack stores a large number of storage plates holding a plurality of containers in the vertical direction, and the low-temperature storage tank is partitioned into two or more storage areas by at least one partition wall, A space above the storage chamber is held by the storage plate, storage rack transporting means for taking in and out the storage rack, storage plate transfer means for transferring the storage plate between the storage rack and the storage area, and the storage plate. Picking means for individually handling the containers in the storage area, and the container storage means includes the storage rack transport means and storage plate transfer means. By the upper space of the unit and picking means integral to the cold storage chamber is configured to be movable, it is to solve the above problems.

According to the low-temperature storage system according to claim 1, the inside of the low-temperature storage tank can be maintained at a cryogenic temperature equivalent to that of the low-temperature storage chamber by including the low-temperature storage tank and the refrigerant pipe that open upward and store the container. The container storage means having the low temperature storage tank is configured to be movable in the upper space of the low temperature storage chamber, so that the container taken out in the upper space of the low temperature storage chamber is quickly stored in the cryogenic low temperature storage tank. Therefore, the container during the extraction operation can be kept long in a cryogenic environment.
As a result, a plurality of containers are supported by the storage plate, etc., and when the storage plate is taken out, only the target container is extracted and carried out to the outside, and the storage plate is stored again when stored in the low temperature storage chamber. It is possible to prevent the deterioration of the sample contained in the container and the occurrence of dew condensation on the container. The sample will not deteriorate and cause damage, and it will freeze and the storage plate and container will adhere to the next container. Picking does not become difficult.

Furthermore, since the upper part of the low-temperature storage tank is open, picking work from a storage plate or the like can be performed in a state where the container is stored in the low-temperature storage tank, and the container is placed in a cryogenic environment during the extraction operation. It is also possible to keep it down longer.
In addition, since only the inside of the low temperature storage tank is kept at a very low temperature, it is not necessary to keep the other spaces at a very low temperature. Therefore, a general transfer mechanism, industrial robot, etc. It can be used, and there is no need to use special equipment that can operate at extremely low temperatures, it can be operated at high speed, costs are reduced, and maintenance work immediately after operation is facilitated.

According to the configuration of claim 2, when the low temperature storage tank is partitioned into two or more storage areas by at least one partition wall, when the inside of the low temperature storage tank moves in the upper space of the low temperature storage chamber, Alternatively, when picking work or the like is performed in the low temperature storage tank, the cold air in the low temperature storage tank is less likely to leak to the outside, the temperature rise is suppressed, and the container is more reliably placed in a cryogenic environment. Can keep.
Further, since the refrigerant pipe is provided along the inner wall and the partition wall of the low temperature storage tank, each storage area in the low temperature storage tank can be reliably and uniformly cooled.
According to the structure of Claim 3, it becomes possible to cool each accommodation area | region more efficiently and equally because the inner wall and partition wall of a low-temperature accommodation tank are metal.
According to the configuration of the fourth aspect, the partition plate is provided inside the storage area, a cold air circulation space is formed between the partition plate and the inner wall or partition wall of the low temperature storage tank, and the refrigerant pipe is cool air. Because it is provided in the circulation space, the cold air cooled by the refrigerant pipes can be equally lowered in the cold air circulation space, and each storage area can be more efficiently and evenly cooled via the partition plate. It becomes.
In addition, the lower end of the partition plate may be separated from the bottom, so that the cold air in the cold air circulation space cooled by the refrigerant pipe is supported by a storage plate or the like placed on the bottom of each storage area The container can be efficiently fed into the container, and the container can be more reliably kept in a cryogenic environment.

According to the configuration of claim 5, the circulation plate is provided above the cold air circulation space, so that the cold air cooled by the refrigerant pipe is positively placed on the bottom of each storage area. For example, the container can be fed toward the container supported by, for example, and the container can be reliably maintained in a cryogenic environment.
According to the configuration described in claim 6, when the low temperature storage tank is provided with the upper wall that closes a part of the opening above the storage area, the low temperature storage tank moves in the upper space of the low temperature storage chamber. Or when picking work by a picking mechanism etc. is performed, it can further suppress that the cool air in a low temperature storage tank leaks outside, and temperature rises.
According to the structure of Claim 7, it becomes possible to cool the inside of a low-temperature storage tank more effectively because the refrigerant pipe was provided along the lower surface of the upper wall.
According to the configuration described in claim 8, the refrigerant pipe is provided so as to come into contact with the inner wall and the partition wall of the low temperature storage tank. It becomes possible to cool the inside.
According to the structure of Claim 9, when a refrigerant pipe has a radiation fin, it becomes possible to cool the inside of a low-temperature storage tank more efficiently.

According to the structure of Claim 10, while the heat insulation wall was provided in the outer side of the inner wall of a low-temperature storage tank, the temperature rise in a low-temperature storage tank can be prevented, and a refrigerant pipe is provided in the outer side of a heat insulation wall. By providing the cooling means for supplying the refrigerant, the low-temperature storage tank can be moved together with the cooling means in the upper space of the low-temperature storage chamber, and equipment such as piping can be simplified.
According to the structure of claim 11, the open / close lid that can close and open the upper opening is provided in the low-temperature storage tank. It can further suppress that the cool air in a tank leaks outside and temperature rises.
According to the structure of claim 12, since it becomes possible to perform the picking operation in a state where the low temperature storage tank is stopped above the position where the designated container of the low temperature storage chamber is stored, After being stored in the storage tank, it is possible to shorten the time until the container to be stored in the low temperature storage room is returned again, and the container to be stored in the low temperature storage room is stored in the low temperature storage tank again. There is no need to move the low temperature storage tank.
As a result, it is possible to more reliably suppress the deterioration of the sample stored in the container to be stored in the low temperature storage chamber and the occurrence of condensation on the container.

1 is a schematic perspective view of a cryogenic storage system according to an embodiment of the present invention. Explanatory drawing of the storage plate and container which one Embodiment of this invention handles. The front view of the low-temperature storage system which concerns on one Embodiment of this invention. The top view of the cryogenic storage system which concerns on one Embodiment of this invention. BRIEF DESCRIPTION OF THE DRAWINGS FIG. The top view of the container accommodating means of the low-temperature storage system which concerns on one Embodiment of this invention. The side view of the container accommodating means of the low-temperature storage system which concerns on one Embodiment of this invention. The (a) bottom view and (b) side view of the opening-and-closing lid of the low-temperature storage system concerning one embodiment of the present invention. The plane view sectional view of the cryogenic storage tank of the cryogenic storage system concerning one embodiment of the present invention. Sectional drawing of FIG. The plane view sectional view of the cryogenic storage tank of the cryogenic storage system concerning other embodiments of the present invention.

  The low-temperature storage system of the present invention includes a low-temperature storage chamber that stores a plurality of containers that store samples, and a container storage means that can move in an upper space of the low-temperature storage chamber and can hold the containers. A storage system, wherein the container storage means includes a low-temperature storage tank that opens upward and stores the container, and a refrigerant pipe that cools the inside of the low-temperature storage tank, without increasing the temperature of the container during the extraction operation, It prevents deterioration of the sample contained in the container and the occurrence of condensation on the container, does not require special equipment, can operate at high speed, reduces manufacturing and operation costs, and is easy to operate. As long as there is any specific configuration, any configuration may be used.

An outline of a cryogenic storage system 100 according to an embodiment of the present invention will be described with reference to FIGS. 1 to 5 (in each figure, a part of the configuration is omitted or simplified for explanation). It does not accurately represent the actual dimensions and structure.)
A plurality of containers C that contain samples to be handled by the cryogenic storage system 100 according to an embodiment of the present invention are supported in a matrix on the storage plate P, as shown in FIG.
As shown in FIGS. 1, 3, and 4, the low temperature storage system 100 includes a plurality of storage plates P that are stacked in a vertical direction on a storage rack 151, and the storage rack 151 is stored in the low temperature storage chamber 101 from above. It is configured to be stored.

The upper space of the low-temperature storage chamber 101 constitutes a work chamber 102, and the container storage means 110 having a low-temperature storage tank 120 that is open at the top and stores the container is movable in the work chamber 102. Has been placed.
Further, as shown in FIGS. 1 and 3 to 5, the storage rack transport means 152 for taking the storage rack 151 into and out of the low temperature storage chamber 101 and the storage plate P are transferred between the storage rack 151 and the low temperature storage tank 120. Storage plate transfer means 153 (consisting of storage plate pulling means 155 and storage plate transfer means 156) and picking means 154 for individually handling containers C held on the storage plate P in the low temperature storage tank 120. Is disposed so as to be movable integrally with the container housing means 110.

In the present embodiment, a loading / unloading chamber 103 for loading / unloading the storage plate P from the outside is provided at the end of the working chamber 102.
In the carry-in / out chamber 103, a plate turning table 161 on which the storage plate P is placed is arranged so as to be turnable so as to face the carry-in / out door 162 side and the container housing means 110, and is externally connected via the carry-in / out door 162. The storage plate P is moved in and out, and the container housing means 110 is moved to an adjacent position, so that the storage plate P is transferred to and from the low temperature storage tank 120 by the storage plate transfer means 156. It is configured.

Next, the container accommodating means 110 of the low-temperature storage system 100 according to an embodiment of the present invention will be described with reference to FIGS. 6 to 10 (in each figure, a part of the configuration is omitted or simplified for explanation). It does not represent the actual dimensions and structure accurately.)
As shown in FIGS. 6 and 7, the container housing means 110 includes a low-temperature storage tank 120 that is surrounded by a heat insulating wall 127 and that opens upward and stores the container. A cooling means 113 for supplying a refrigerant to the refrigerant pipe 121 is integrally provided, and an open / close lid 128 is provided above the low-temperature storage tank 120.

As shown in FIG. 8, the opening / closing lid 128 is provided with a packing 129 on the lower surface side thereof, and as shown in FIG.
Note that the opening / closing operation of the opening / closing lid 128 is performed by a slight vertical movement at the closed position and sliding in the left-right direction in FIG. 7, but other operations such as a turning movement depending on the arrangement relationship with other configurations. Alternatively, a plurality of operations may be performed in combination.

As shown in FIGS. 9 and 10, the inside of the low-temperature storage tank 120 of the container storage means 110 is partitioned into four storage regions 111 by three partition walls 122, and a refrigerant pipe 121 for cooling the interior is It is provided along the inner wall 123 of the accommodation area | region 111 of both surfaces of the partition wall 122, and both ends.
As shown in FIG. 9, the storage plate P is configured to be placed on the bottom of each storage area 111.
In the present embodiment, each partition wall 122 and inner wall 123 are made of metal, and the refrigerant pipe 121 is provided so as to be in contact with the partition wall 122 and the inner wall 123, thereby cooling each accommodation region more efficiently and evenly. It is configured as follows.
In addition, you may comprise so that cooling efficiency may be raised further by providing the refrigerant | coolant pipe | tube 121 with a radiation fin suitably.
When each partition wall 122 is made of metal and the refrigerant pipe 121 is provided so as to be in contact with the partition wall 122, the refrigerant pipe 121 may be provided on any one side surface of each partition wall 122.

As shown in FIG. 9, a partition plate 124 formed of a punching plate, an aluminum plate, or the like is provided inside each accommodation region 111.
A cool air circulation space 112 in which the refrigerant pipe 121 exists is formed between the partition plate 124 and the inner wall 123 or the partition wall 122.
The sectional area inside the partition plate 124 is set so that the work by the picking means, the storage plate transfer means and the like can be performed without any trouble.
As a result, the temperature can be evenly reduced in the cool air circulation space 112, and the respective accommodation regions 111 can be more efficiently and uniformly cooled via the partition plate 124.
When the lower end of the partition plate 124 is separated from the bottom as shown in the figure, the cold air circulation space 112 functions as a duct, and the air cooled by the refrigerant pipe 121 descends in the cold air circulation space 112 and is It is possible to efficiently feed the storage plate P placed on the bottom of the storage area 111, and the container supported by the storage plate P can be reliably maintained in a cryogenic environment.
In order to perform this air flow more positively, a circulation fan 125 may be provided above the cool air circulation space 112 as shown in FIG.

As shown in FIG. 10, the upper wall 126 is provided so as to partially close from the side, and the refrigerant pipe 121 is provided along the lower surface of the upper wall 126. It has been.
As a result, when the space above the low temperature storage chamber 101 is moved, or when work is performed by picking means, storage plate transfer means, etc., the cold air in each storage area 111 leaks to the outside and the temperature rises. In addition, it is possible to effectively cool the interior of each housing region 111 by the refrigerant pipe 121 provided along the lower surface of the upper wall 126.

The extraction operation of the designated container C in the low-temperature storage system 100 according to the embodiment of the present invention configured as described above will be described.
First, the operator places an empty storage plate P on the plate turning table 161 from the carry-in / out door 162 on the side surface of the carry-in / out chamber 103, closes the carry-in / out door 162, and then starts the control device (not shown). Give instructions.
The empty storage plate P is directed to the side facing the container accommodating means 110 by the rotation of the plate turning table 161, and the container accommodating means 110 is adjacent to the carry-in / out chamber 103 integrally with the storage plate transfer means 153. Move to position.
In this state, the storage plate pulling means 155 takes out the storage plate P from the plate turning table 161, and the storage plate transfer means 156 transfers the empty storage plate P to the bottom of one of the storage areas 111 of the container storage means 110. Included.

Next, the container storage means 110 moves to the position of the storage rack 151 in which the storage plate P that supports the designated container C is stored. Here, the storage rack transporting means 152 pulls the storage rack 151 upward from the low temperature storage chamber 101, and the storage plate pulling means 155 takes out the storage plate P that supports the designated container C from the storage rack 151.
Then, the storage plate transfer means 156 moves, and the storage plate P that supports the designated container C is transferred to the bottom of one of the storage areas 111 of the container storage means 110.

In this state, the picking means 154 operates and the designated container C is transferred to the empty storage plate P.
Thereafter, the storage plate P that supports the designated container C is returned to the original storage rack 151 and stored in the low temperature storage chamber 101 in the reverse procedure to the above operation, and the designated storage plate on which the designated container C is transferred. P is returned to the carry-in / out chamber 103 and the worker carries out the carry-in / out door 162.
When a plurality of containers C to be taken out are designated, the process from taking out the storage plate P supporting the designated container C from the low temperature storage chamber 101 and returning it is repeated a plurality of times.

In the above operation, since the storage region 111 in the low temperature storage tank 120 is maintained at a cryogenic temperature similar to the low temperature storage chamber 101, the time during which the container C is exposed to the ambient temperature of the work chamber 102 is very short. The sample stored in the container C to be stored again can be prevented from being altered and the condensation on the container C being prevented, the sample is not altered and damaged, and the sample is frozen and stored in the storage plate P. C does not adhere and the next picking of the container C does not become difficult.
Further, since the inside of the low temperature storage tank 120 is partitioned into a plurality of storage areas 111 by the partition wall 122, the storage area is also moved when moving in the upper space of the low temperature storage chamber 101 or when picking work or the like is performed. The cold air of 111 is less likely to leak to the outside, and even if these operations are performed a plurality of times, the temperature rise is suppressed, and the container C can be reliably kept in a cryogenic environment.

The low-temperature storage system 100 according to the present invention is not limited to the above-described embodiment, and the container storage means cools the inside of the low-temperature storage tank and the low-temperature storage tank that opens upward and stores the container. If it is provided with a refrigerant pipe, each specific configuration can be replaced with the configuration of a known cryogenic storage system.
Further, the object to be stored in a frozen state is not limited to a sample used for basic research or applied research such as chemistry, biochemistry, biology, and pharmaceutical, and any object may be used.

DESCRIPTION OF SYMBOLS 100 ... Low temperature storage system 101 ... Low temperature storage chamber 102 ... Work room 103 ... Carrying-in / out chamber 110 ... Container accommodation means 111 ... Storage area 112 ... Cold air circulation space 113 ... Cooling means 120 ... low temperature storage tank 121 ... refrigerant pipe 122 ... partition wall 123 ... inner wall 124 ... partition plate 125 ... circulation fan 126 ... upper wall 127 ... heat insulation Wall 128 ... Opening / closing lid 129 ... Packing 151 ... Storage rack 152 ... Storage rack transport means 153 ... Storage plate transfer means 154 ... Picking means 155 ... Storage plate pulling means 156 ..Storage plate transfer means 161... Plate turning table 162 .. carry-in / out door P .. storage plate C .. container

Claims (12)

A low-temperature storage system comprising a low-temperature storage chamber for storing a plurality of containers containing samples, a container storage means capable of moving the upper space of the low-temperature storage chamber and capable of holding the containers,
The low-temperature storage system, wherein the container storage means includes a low-temperature storage tank that opens upward and stores the container, and a refrigerant pipe that cools the inside of the low-temperature storage tank. The low temperature storage tank is partitioned into two or more storage areas by at least one partition wall;
The low-temperature storage system according to claim 1, wherein the refrigerant pipe is provided along an inner wall and the partition wall of the low-temperature storage tank.   The low temperature storage system according to claim 2, wherein the inner wall and the partition wall of the low temperature storage tank are made of metal. A partition plate is provided inside the housing area,
A cold air circulation space is formed between the partition plate and the inner wall of the low temperature storage tank or the partition wall,
The low-temperature storage system according to claim 2 or 3, wherein the refrigerant pipe is provided in the cold air circulation space.   The low-temperature storage system according to claim 4, wherein a circulation fan is provided above the cold air circulation space.   The low-temperature storage system according to any one of claims 2 to 5, wherein the low-temperature storage tank is provided with an upper wall that closes a part of an opening above the storage area.   The cryogenic storage system according to claim 6, wherein the refrigerant pipe is provided along a lower surface of the upper wall.   The low-temperature storage system according to any one of claims 2 to 7, wherein the refrigerant pipe is provided in contact with an inner wall of the low-temperature storage tank and the partition wall.   The low-temperature storage system according to any one of claims 2 to 8, wherein the refrigerant pipe has a heat radiation fin. On the outside of the inner wall of the low temperature storage tank, a heat insulating wall is provided,
The low-temperature storage system according to any one of claims 1 to 9, wherein cooling means for supplying a refrigerant to the refrigerant pipe is provided outside the heat insulating wall.   The low-temperature storage system according to any one of claims 1 to 10, wherein the low-temperature storage tank is provided with an opening / closing lid capable of closing and opening an upper opening. The low-temperature storage chamber is configured to store a plurality of storage racks so that they can be taken in and out from above,
The storage rack accommodates a large number of storage plates holding a plurality of containers in the vertical direction,
The low temperature storage tank is partitioned into two or more storage areas by at least one partition wall;
In the space above the cryogenic storage chamber, storage rack transport means for taking in and out the storage rack, storage plate transfer means for transferring the storage plate between the storage rack and the storage area, and the storage plate Picking means for individually handling the held containers in the accommodation area,
The said container accommodating means is comprised so that the upper space of the said low temperature storage chamber is movable integrally with the said storage rack conveyance means, the storage plate transfer means, and the picking means, The any one of Claim 1 thru | or 11 characterized by the above-mentioned. The cryogenic storage system described in Crab.

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