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JP4707224B2 - Lesion detection device using puncture needle - Google Patents

Lesion detection device using puncture needle Download PDF

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Publication number
JP4707224B2
JP4707224B2 JP2000388327A JP2000388327A JP4707224B2 JP 4707224 B2 JP4707224 B2 JP 4707224B2 JP 2000388327 A JP2000388327 A JP 2000388327A JP 2000388327 A JP2000388327 A JP 2000388327A JP 4707224 B2 JP4707224 B2 JP 4707224B2
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JP
Japan
Prior art keywords
puncture needle
output
lesion
oscillation
phase comparator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2000388327A
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Japanese (ja)
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JP2002186623A (en
Inventor
信長 渋谷
和人 小林
晴ひこ 千木良
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Honda Electronics Co Ltd
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Honda Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Priority to JP2000388327A priority Critical patent/JP4707224B2/en
Publication of JP2002186623A publication Critical patent/JP2002186623A/en
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Description

【0001】
【発明が属する技術分野】
本発明は、生体内の病変部の組織採取を正確にするための穿刺針による病変部検出装置に関するものである。
【0002】
【従来の技術】
従来、乳癌診断において、穿刺針による病変部の組織採取は、超音波診断装置で、超音波振動子から体内に照射した超音波の反射波により病変部の画像をCRT等の表示装置で表示し、この表示装置に表示された穿刺針と病変部の位置を確認しながら行っているが、現状の超音波診断装置の画像分解能では、細い穿刺針と微小な病変部の組織の検出が困難であるため、医療現場において、医師は穿刺針の先端が病変部から受ける抵抗を、穿刺針を持つ手の感覚で感じ取り、病変部内への穿刺針の先端の到達を確認してから組織の吸引作業を行っており、このような穿刺針の先端が確実に微小な病変部内に到達していることを確認することは誤診を防ぐ上で重要である。
【0003】
【発明が解決しようとする課題】
しかしながら、このような病変部組織は正常な組織に比べて硬いので、穿刺針の先端が受ける抵抗変化から病変部を推測することはできるが、この感覚に頼った判断は、医師の個人差、経験及び年齢に左右されるので、定量的に病変部を検出する方法が望まれていた。
【0004】
【課題を解決しようとする手段】
本発明は、病変部の組織採取をする穿刺針と、該穿刺針に固着した超音波振動子と、該超音波振動子に発振出力を印加する発振装置と、該発振装置からの発振出力の電流変化を検出する電流検出部と、前記発振装置の発振出力の電圧と前記電流検出部で検出した検出電流の位相を比較する位相比較器、該位相比較器の出力により前記病変部を検出する検出部とからなるものであり、前記検出部は前記位相比較器の出力を低域フィルタにより平滑化された信号を通過させ、前記低域フィルタの出力電圧を電圧制御発振器に入力し、該電圧制御発振器の出力を増幅器で増幅して可聴音発生器で出力してもよいし、又、前記位相比較器の出力を増幅器で増幅して発光装置で表示してもよいし、さらに、前記位相比較器の出力を増幅器で増幅してメータで表示もよい。
【0005】
【発明の実施の形態】
本発明では、穿刺針に超音波振動子を装着して、穿刺針を超音波振動させ、超音波振動子に入力する発振出力の電圧と発振出力の電流の位相の変化を検出し、この位相変化を可聴音の変化で検出するか、光の変化で検出するか、メータの指針の振れで検出することができる。
【0006】
【実施例】
まず、本発明の実施例を説明する前に本発明の原理を説明すると、図1において、圧電振動子2を装着した穿刺針1によって患者3の体内にある病変部4を検出するために、圧電振動子2に超音波発振器5から発振出力を印加する場合、この振動系の機械インピーダンスをZ0、負荷インピーダンスをZa、圧電振動子2の力係数をA、制動アドミッタンスをYdとして振動系の電気的等価回路を示すと、図2のようになり、このとき、穿刺針1の先端に病変部4が接触すると、その病変部4の硬さによって振動系に加わる負荷インピーダンスZaが変化するが、一般的に、どんな振動系についても、負荷インピーダンスZaが変化すると、図2の電気的等価回路により機械共振周波数f0、電気インピーダンスZ、位相差θが変化することが分かっているので、それらの変化量のうちの一つから硬い対象物体の病変部4の組織の検出が可能である。
【0007】
図3は本発明の1実施例の穿刺針の構成図で、穿刺針1に金属円板6が固定され、金属円板6に円板状の圧電振動子7を接着することにより、図4に示すように、円板振動子7の節円1個で面に垂直に屈曲振動するB10モードを用い、屈曲振動を縦振動に変換し、穿刺針1に縦振動を励振させたことであり、このように、穿刺針1を縦振動させることにより、穿刺針1の側面の負荷による機械インピーダンスの影響を少なくし、穿刺針1の先端の負荷による機械インピーダンス変化を大きく受けるようにしたものである。これにより、穿刺針1の側面は患者3の体内の組織の影響を受けないで、穿刺針1の先端に接触する病変部4の組織だけを正確に検出することが可能になる。
【0008】
図5は本発明の実施例の穿刺針による病変部検出装置のブロック図で、穿刺針1に装着した圧電振動子7に超音波発振回路8から発振出力が印加されるとともに、位相比較器9の一方の端子に超音波発振回路8から発振出力が印加され、又、超音波発振回路8の出力コードに電流検出部10が装着され、この電流検出部10の出力は位相比較器9の他方の端子に印加され、位相比較器9で超音波発振回路8からの発振出力の電圧の位相と電流検出部10の出力の電流の位相が比較され、この位相差の信号を病変部検出回路11に入力する。
【0009】
このように構成した本実施例では、図1の患者3の体内に穿刺針1を刺すと、穿刺針1の先端が病変部4に接触するまでは、穿刺針1に装着した圧電振動子7に入力する超音波発振回路8からの発振出力の電圧と圧電振動子7に入力する発振出力の電流の位相差はわずかであるので、位相比較器9の出力は少ないが、穿刺針1の先端が病変部4に接触すると、位相差は大きく変化するため、位相差比較器9からの出力が大きくでるので、この出力は病変部検出回路11に設けた増幅器で増幅され、又、病変部検出回路11に設けたスピーカによる可聴音、発光素子による光、及びメータ等の指針の振れ等によの大きな変化により、穿刺針1の先端が病変部4に到達したことを検出することができる。
【0010】
図6は本発明の他の実施例の病変部検出装置のブロック図で、超音波発振回路8は発信器8aと増幅器8bが接続され、増幅器8bの出力端子は穿刺針1の圧電振動子7に接続されるとともに位相比較器9の一方の端子に接続され、電流検出部10は位相比較器9の他方の端子に接続され、病変部検出部11には、低域フィルタ11a、電圧制御発振器11b、増幅器11cが順次接続され、増幅器11cの出力端子にスピーカ12が接続されている。
【0011】
このように構成した本実施例の病変部検出装置では、超音波発振回路8によって円板の圧電振動子7のB10モードで振動する共振周波数で発振を行って圧電振動子7を駆動すると、圧電振動子7の駆動電圧及び電流が位相比較器9に入力されるので、低域フィルタ11aによって位相比較器9からの位相差信号を平滑化し、その直流電圧で電圧制御発振器11bの可聴域発振周波数を制御し、そして、電圧制御発信器10bからの出力は増幅器11cによって増幅され、スピーカ12を駆動する。
【0012】
このような病変部検出装置を用いることにより、医師は穿刺針1を用いた手術の際、両手及び目は手術に捕らわれる場合が多いので、スピーカ12からの可聴音の変化によって穿刺針1が病変部4に到達したかどうか正確に知ることができ、誤診をすることが無いという利点がある。
【0013】
なお、図6の実施例において、スピーカ12以外にも、発光素子を接続して、発光素子による光の変化で検出してもよいし、又、メータを接続して、メータの指針の振れにより検出してもよい。
【0014】
【発明の効果】
以上説明したように、本発明の穿刺針による病変部検出装置では、穿刺針に超音波振動子を装着して、穿刺針を超音波振動させ、超音波振動子に入力する発振出力の電圧と発振出力の電流の位相の変化を検出し、この位相変化を可聴音の変化で検出するか、光の変化で検出するか、メータの指針の振れで検出することができるので、穿刺針を用いた手術の際、穿刺針が病変部に到達したかどうか正確に知ることができ、誤診をすることが無いという利点がある。
【図面の簡単な説明】
【図1】 本発明の原理を説明するための図である。
【図2】 図1の原理を説明するための等価回路図である。
【図3】 本発明の1実施例の穿刺針の構成図である。
【図4】 図3の穿刺針の振動モードを示した図である。
【図5】 本発明の実施例の穿刺針による病変部検出装置のブロック図である。
【図6】 本発明の他の実施例の病変部検出装置のブロック図である。
【符号の説明】
1 圧電振動子
2 穿刺針
3 患者
4 病変部
5 超音波発信器
6 超音波発振器
7 圧電振動子
8 超音波発振回路
9 位相比較器
10 電流検出部
11 病変部検出回路
12 スピーカー
[0001]
[Technical field to which the invention belongs]
The present invention relates to a lesion detection apparatus using a puncture needle for accurately collecting a tissue of a lesion in a living body.
[0002]
[Prior art]
Conventionally, in the diagnosis of breast cancer, the tissue of a lesioned part is collected with a puncture needle using an ultrasonic diagnostic device, and an image of the lesioned part is displayed on a display device such as a CRT by the reflected wave of the ultrasonic wave irradiated into the body from the ultrasonic transducer. However, the puncture needle displayed on this display device and the position of the lesion are confirmed, but with the current image diagnostic resolution of the ultrasonic diagnostic apparatus, it is difficult to detect the thin puncture needle and the tissue of the minute lesion. Therefore, in the medical field, the doctor senses the resistance that the tip of the puncture needle receives from the lesioned part with the sensation of the hand holding the puncture needle, and confirms the arrival of the tip of the puncture needle into the lesioned part before sucking tissue In order to prevent misdiagnosis, it is important to confirm that the tip of such a puncture needle has surely reached a minute lesion.
[0003]
[Problems to be solved by the invention]
However, since such lesion tissue is harder than normal tissue, it is possible to infer the lesion from the resistance change experienced by the tip of the puncture needle. Since it depends on experience and age, a method for quantitatively detecting a lesion has been desired.
[0004]
[Means to solve the problem]
The present invention relates to a puncture needle for sampling a tissue of a lesioned part, an ultrasonic transducer fixed to the puncture needle, an oscillation device for applying an oscillation output to the ultrasonic transducer, and an oscillation output from the oscillation device. a current detector for detecting a current change, a phase comparator for comparing the phase of the detection current detected by the voltage of the oscillation output of the oscillator device and said current detecting unit, detecting the lesion by the output of the phase comparator The detection unit passes the signal smoothed by the low-pass filter, and inputs the output voltage of the low-pass filter to a voltage controlled oscillator, The output of the voltage controlled oscillator may be amplified by an amplifier and output by an audible sound generator, or the output of the phase comparator may be amplified by an amplifier and displayed by a light emitting device. Amplify the output of the phase comparator with an amplifier. Display in the data may be.
[0005]
DETAILED DESCRIPTION OF THE INVENTION
In the present invention, an ultrasonic transducer is attached to the puncture needle, the puncture needle is ultrasonically vibrated, and a change in the phase of the oscillation output voltage and the oscillation output current input to the ultrasonic transducer is detected. The change can be detected by a change in audible sound, a change in light, or a shake of a meter pointer.
[0006]
【Example】
First, the principle of the present invention will be described before describing the embodiment of the present invention. In FIG. 1, in order to detect the lesioned part 4 in the body of the patient 3 by the puncture needle 1 to which the piezoelectric vibrator 2 is attached, When an oscillation output is applied to the piezoelectric vibrator 2 from the ultrasonic oscillator 5, the mechanical impedance of the vibration system is Z0, the load impedance is Za, the force coefficient of the piezoelectric vibrator 2 is A, and the braking admittance is Yd. A typical equivalent circuit is shown in FIG. 2, and when the lesioned part 4 comes into contact with the tip of the puncture needle 1, the load impedance Za applied to the vibration system changes depending on the hardness of the lesioned part 4. In general, for any vibration system, when the load impedance Za changes, the mechanical resonance frequency f0, the electrical impedance Z, and the phase difference θ change according to the electrical equivalent circuit of FIG. Therefore, it is possible to detect the tissue of the lesioned part 4 of the hard target object from one of these changes.
[0007]
FIG. 3 is a configuration diagram of a puncture needle according to an embodiment of the present invention. A metal disc 6 is fixed to the puncture needle 1 and a disc-shaped piezoelectric vibrator 7 is bonded to the metal disc 6 to thereby form FIG. As shown in FIG. 5, the B10 mode in which one nodal circle of the disc vibrator 7 is bent and vibrated perpendicularly to the surface is used, the bending vibration is converted into the longitudinal vibration, and the puncture needle 1 is excited with the longitudinal vibration. Thus, by causing the puncture needle 1 to vibrate longitudinally, the influence of the mechanical impedance due to the load on the side surface of the puncture needle 1 is reduced, and the mechanical impedance change due to the load at the tip of the puncture needle 1 is greatly affected. is there. As a result, the side surface of the puncture needle 1 is not affected by the tissue in the body of the patient 3, and only the tissue of the lesioned part 4 that contacts the tip of the puncture needle 1 can be accurately detected.
[0008]
FIG. 5 is a block diagram of a lesion detection device using a puncture needle according to an embodiment of the present invention. An oscillation output is applied from an ultrasonic oscillation circuit 8 to a piezoelectric vibrator 7 attached to the puncture needle 1 and a phase comparator 9 is provided. The oscillation output from the ultrasonic oscillation circuit 8 is applied to one of the terminals, and the current detection unit 10 is attached to the output code of the ultrasonic oscillation circuit 8, and the output of the current detection unit 10 is the other of the phase comparator 9. And the phase comparator 9 compares the phase of the oscillation output voltage from the ultrasonic oscillation circuit 8 with the phase of the current output from the current detection unit 10, and uses this phase difference signal as the lesion detection circuit 11. To enter.
[0009]
In the present example configured as described above, when the puncture needle 1 is inserted into the body of the patient 3 in FIG. 1, the piezoelectric vibrator 7 attached to the puncture needle 1 until the tip of the puncture needle 1 contacts the lesioned part 4. Since the phase difference between the oscillation output voltage input from the ultrasonic oscillation circuit 8 and the oscillation output current input to the piezoelectric vibrator 7 is slight, the output of the phase comparator 9 is small, but the tip of the puncture needle 1 Since the phase difference changes greatly when the touches the lesion 4, the output from the phase difference comparator 9 is increased. This output is amplified by the amplifier provided in the lesion detection circuit 11, and the lesion detection is performed. It is possible to detect that the tip of the puncture needle 1 has reached the lesioned part 4 by a large change caused by an audible sound from a speaker provided in the circuit 11, light from a light emitting element, and a shake of a pointer such as a meter.
[0010]
FIG. 6 is a block diagram of a lesion detection apparatus according to another embodiment of the present invention. An ultrasonic oscillator 8 is connected to a transmitter 8a and an amplifier 8b, and an output terminal of the amplifier 8b is a piezoelectric vibrator 7 of the puncture needle 1. And the current detector 10 is connected to the other terminal of the phase comparator 9. The lesion detector 11 includes a low-pass filter 11a, a voltage-controlled oscillator. 11b and an amplifier 11c are sequentially connected, and a speaker 12 is connected to an output terminal of the amplifier 11c.
[0011]
In the lesion detection apparatus of this embodiment configured as described above, when the piezoelectric oscillator 7 is driven by oscillating at the resonance frequency that vibrates in the B10 mode of the piezoelectric vibrator 7 of the disk by the ultrasonic oscillation circuit 8, the piezoelectric vibrator 7 is driven. Since the driving voltage and current of the vibrator 7 are input to the phase comparator 9, the phase difference signal from the phase comparator 9 is smoothed by the low-pass filter 11a, and the audible oscillation frequency of the voltage controlled oscillator 11b is obtained by the DC voltage. The output from the voltage control oscillator 10b is amplified by the amplifier 11c and drives the speaker 12.
[0012]
By using such a lesion detection device, doctors often have their hands and eyes caught during surgery using the puncture needle 1, so that the puncture needle 1 is affected by changes in audible sound from the speaker 12. There is an advantage that it is possible to know exactly whether or not the unit 4 has been reached, and there is no misdiagnosis.
[0013]
In the embodiment of FIG. 6, in addition to the speaker 12, a light emitting element may be connected to detect the change in the light by the light emitting element, or a meter may be connected and the meter pointer shakes. It may be detected.
[0014]
【The invention's effect】
As described above, in the lesion site detection apparatus using a puncture needle of the present invention, an ultrasonic transducer is attached to the puncture needle, the puncture needle is ultrasonically vibrated, and the oscillation output voltage input to the ultrasonic transducer The change in the phase of the current of the oscillation output is detected, and this phase change can be detected by a change in audible sound, by a change in light, or by a shake of a meter pointer. During surgery, there is an advantage that it is possible to know accurately whether the puncture needle has reached the lesion, and there is no misdiagnosis.
[Brief description of the drawings]
FIG. 1 is a diagram for explaining the principle of the present invention.
FIG. 2 is an equivalent circuit diagram for explaining the principle of FIG. 1;
FIG. 3 is a configuration diagram of a puncture needle according to one embodiment of the present invention.
4 is a diagram showing a vibration mode of the puncture needle of FIG. 3. FIG.
FIG. 5 is a block diagram of a lesion detection apparatus using a puncture needle according to an embodiment of the present invention.
FIG. 6 is a block diagram of a lesion detection apparatus according to another embodiment of the present invention.
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 Piezoelectric vibrator 2 Puncture needle 3 Patient 4 Lesion part 5 Ultrasonic transmitter 6 Ultrasonic oscillator 7 Piezoelectric vibrator 8 Ultrasonic oscillation circuit 9 Phase comparator 10 Current detection part 11 Lesion part detection circuit 12 Speaker

Claims (4)

病変部の組織採取をする穿刺針と、該穿刺針に固着した超音波振動子と、該超音波振動子に発振出力を印加する発振装置と、該発振装置からの発振出力の電流変化を検出する電流検出部と、前記発振装置の発振出力の電圧と前記電流検出部で検出した検出電流の位相を比較する位相比較器、該位相比較器の出力により前記病変部を検出する検出部とからなることを特徴とする穿刺針による病変部検出装置。A puncture needle for collecting tissue from a lesion, an ultrasonic transducer fixed to the puncture needle, an oscillation device for applying an oscillation output to the ultrasonic transducer, and a current change in the oscillation output from the oscillation device are detected. a current detection unit which, a phase comparator for comparing the phase of the detection current detected by the voltage of the oscillation output of the oscillation device and the current detection unit, a detecting unit for detecting a lesion by the output of the phase comparator A lesion detection device using a puncture needle, comprising: 前記検出部は前記位相比較器の出力を低域フィルタにより平滑化された信号通過させ、前記低域フィルタの出力電圧を電圧制御発振器に入力し、該電圧制御発振器の出力を増幅器で増幅して可聴音発生器で出力することを特徴とする請求項1記載の穿刺針による病変部検出装置。The detector passes the signal smoothed by the low-pass filter the output of the phase comparator, the inputs of the output voltage of the low-pass filter to the voltage controlled oscillator, amplifying the output of said voltage controlled oscillator by an amplifier The lesioned area detecting device using a puncture needle according to claim 1, wherein the lesioned area is output by an audible sound generator. 前記位相比較器の出力を増幅器で増幅して発光装置で表示することを特徴とする請求項1記載の穿刺針による病変部検出装置。  2. A lesion detection apparatus using a puncture needle according to claim 1, wherein the output of the phase comparator is amplified by an amplifier and displayed by a light emitting device. 前記位相比較器の出力を増幅器で増幅してメータで表示することを特徴とする請求項1記載の穿刺針による病変部検出装置。  2. A lesion detection apparatus using a puncture needle according to claim 1, wherein the output of the phase comparator is amplified by an amplifier and displayed on a meter.
JP2000388327A 2000-12-21 2000-12-21 Lesion detection device using puncture needle Expired - Fee Related JP4707224B2 (en)

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