JP2551318B2 - Infusion container - Google Patents

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a container for infusion. More specifically, dry drugs such as powdered preparations, freeze-dried preparations, and solid preparations and their dissolved solutions are stored in a separated state, and the dried drug and the dissolved solutions are aseptically mixed in a container immediately before use. , A container for infusion for supplying as a liquid medicine.

[0002]

2. Description of the Related Art Conventionally, in medical institutions such as hospitals, a dried drug contained in a drug container such as a vial is dissolved in distilled water, a saline solution, a solution such as glucose solution (including other drug solutions), and then an intravenous injection is made. It is used for In order to easily use in such a case, the vial containing the dry drug is connected in series to the flexible container containing the solution,
An infusion container has been proposed in which these two containers are aseptically communicated at the time of use (Japanese Patent Publication No. 61-5011).
No. 29, JP-A No. 2-1277, and Japanese Utility Model Laid-Open No. 63-
135642, etc.).

The one disclosed in Japanese Patent Publication No. 61-501129 is that in which a capsule containing a drug container and a flexible container containing a solution are connected by a tube, which is provided in the tube. The medicine container and the flexible container are communicated with each other by the communication means so that the medicine and the solution are aseptically mixed. In addition, JP-A-2-1277
What is disclosed in the publication is that the capsule containing the drug container is connected to the mouth of the dissolution liquid container at its joint, and the communication means having the communication sequence regulating means is interposed on the joint side of the capsule. Then, after the drug container is pierced by the communication means, the dissolution liquid container is pierced and the two containers are communicated,
The drug and the dissolution liquid are mixed aseptically, and the one disclosed in Japanese Utility Model Laid-Open No. 63-135642 discloses a tubular support ring which is appropriately removable in the seal portion at the mouth of the dissolution liquid container. A double-ended needle is attached to this support ring so that it can slide up and down, and when the double-ended needle is slid downward, the lower needle body punctures the seal part at the mouth of the solution container. It is a thing.

[0004]

Each of the conventional infusion containers described above is a container in which a vial, which is a general distribution form of a dry drug, is directly incorporated and integrated, and in that sense, it is highly versatile. However, these conventional infusion containers, for example, the infusion container disclosed in Japanese Patent Publication No. 61-501129 has a large number of parts, and it takes time to break the breaking member by hand to open the passage. If the member is not completely broken, it will be difficult for the liquid to pass through and it will take time to dissolve.
In addition, the infusion container disclosed in Japanese Patent Application Laid-Open No. 2-1277 discloses, in terms of prevention of contamination of the internal medicine and simplification of communication between the medicine container and the dissolution liquid container, the above-mentioned special table. Although it is considerably improved as compared with the infusion container disclosed in Japanese Patent Laid-Open No. 61-501129, it has drawbacks in that the parts such as the communication sequence regulating means are complicated and the total number of parts is large. Kaisho 63-
The solution container of 135642 has a small number of parts and is relatively easy to operate, but requires a relatively large force for communication. After mixing the drug and the solution, the support ring and the double-ended needle are removed to dissolve the solution container. Since it is necessary to invert and connect an infusion set etc. to the seal part at the mouth of the dissolution liquid container after the double-ended needle is withdrawn, it takes time to operate, and there is a risk that the mixed drug solution will leak when the double-ended needle is withdrawn. is there,
It has drawbacks such as

The present invention has been made in view of the above circumstances, and it is easy to operate, hassle-free, there is no risk of leaking a mixed drug solution, the number of parts is small, and the drug is aseptically dissolved. It is an object of the present invention to provide an infusion container capable of mixing liquids.

[0006]

In order to solve the above problems, the present invention provides a drug container having a mouth portion sealed with a rubber stopper,
A solution container made of a synthetic resin that is press-deformable and has a communication port with the drug container and a drug solution outlet at its both ends, and an upper and lower part interposed between the mouth part of the drug container and the communication port of the solution container. A double-ended needle having puncture needles at both ends, a guide capsule having a connecting end of the open end and the outer wall of the communication port of the dissolution liquid container, and a part of the drug container and the double-ended needle to be slidable downward, and The cap comprises a cap that seals the open end of the guide capsule, and the inner wall of the cap, the inner wall of the guide capsule and the outer wall of the drug container are provided with drug container pressing means for moving the drug container downward, and the cap is attached. When rotated, the drug container moves downward without rotating to reach the double-ended needle, and further moves downward together with the double-ended needle, whereby the rubber stopper at the mouth of the drug container and the sealing member at the communication port of the solution container are closed. Pierced by-ended needle, the drug container and solvent container adopts a fluid vessel comprising so as to be communicated.

[0007]

In FIG. 1, the second engaging projection 62 of the vial guide 6 externally fitted to the medicine container 1 is fitted in the longitudinal groove 41 of the guide capsule 4, and the first engaging projection 61 is the spiral of the cap 5. It is fitted in the groove 51. In this configuration, when the cap 5 is rotated in the clockwise direction, the vial guide 6 does not rotate together with the cap 5 due to the engagement of the second engaging protrusion 61 and the longitudinal groove 41, and thus the first engaging protrusion. Reference numeral 61 moves downward along the spiral groove 51 of the cap 5. Therefore, when the cap 5 is rotated in the clockwise direction, the drug container 1 moves downward together with the vial guide 6, and first, the rubber stopper 12 of the mouth portion 11 of the drug container 1 is moved to the double-ended needle 3.
Was killed by the upper puncture needle 32 and the vial guide 6
Moves further downward together with the drug container 1 and the double-ended needle 3, and the rubber stopper 12 of the drug solution container 1 and the closing film 22 of the solution container 2 are respectively the upper puncture needle 32 and the lower puncture needle 3 of the double-ended needle 3.
Pierced by 3. In this way, the communication operation between the drug container 1 and the solution container 2 is extremely easily achieved by rotating the cap 5.

[0008]

Embodiments of the present invention will now be described with reference to the drawings. 1 is a cross-sectional view of an embodiment of the infusion container of the present invention, FIGS. 2 to 14 are views for explaining main components of the infusion container of FIG. 1, and FIG. 2 is a cross-section of a drug container. FIG. 3, FIG. 3 is a cross-sectional view of the solution container, FIG. 4 is a plan view of FIG. 3, FIG. 5 is a cross-sectional view of a double-ended needle, FIG. 6 is a bottom view of FIG. 5, FIG. 7 is a plan view of FIG. Is a sectional view of a vial guide, FIG. 9 is a bottom view of FIG. 8, FIG. 10 is a sectional view of a guide capsule, and FIG. 11 is FIG.
0 is a plan view, FIG. 12 is a side view of the cap, and FIG. 13 is FIG.
2 is a sectional view taken along line XX of FIG. 2, and FIG. 14 is a plan view of FIG.
Further, FIG. 15 is a sectional view of an essential part of another embodiment.
15 is a sectional view of the stand of FIG. 15, and FIG. 17 is a bottom view of FIG.

As shown in FIG. 1, the infusion container of the present invention comprises a drug container 1, a solution container 2, a double-ended needle 3, a guide capsule 4, a cap 5 and a vial guide 6, and the guide capsule 4 Is the connecting portion 43 of the communication port 21
And the open end of the guide capsule 4 is sealed with a double-ended needle 3 and its mouth 1.
The mouth portion 11 side of the drug container 1 with 1 facing downward is housed so as to be slidable downward in this order. Further, the drug container 1 is attached to the vial guide 6 with its mouth portion 11 exposed. Then, when the cap 5 is rotated clockwise, the drug container 1 is lowered together with the vial guide 6, and the double-ended needle 3 pierces the rubber stopper 12 of the drug container 1 and the closing film 22 of the solution container 2, The containers 1 and 2 are communicated with each other.

The drug container 1 is generally made of glass, as shown in FIG.
As shown in FIG. 4, the mouth 11 is sealed with a sealing member such as a rubber stopper 12, and the rubber stopper 12 is further wound by a cover member 13 made of aluminum or the like and fixed to the mouth 11. . A commercially available drug container can be used as the drug container 1. When assembling the infusion container, the top surface of the cover member 13 is removed and a through hole 14 is formed at a position where the double-ended needle 3 is punctured by the puncture needle. To be done. Body part 1 of drug container 1
On the outer wall of 5, the first of the vial guide 6 as shown in FIG.
The engagement protrusions 61 and the second engagement protrusions 62 may be provided and the vial guide 6 may be omitted, but it is difficult to form the engagement protrusions on the glass drug container. It is preferable to form the vial guide 6 from a synthetic resin and insert the drug container 1 therein. The drug container 1 contains a dry preparation such as a powder preparation, a solid preparation, and a freeze-dried preparation, but they are omitted in the drawing.

The vial guide 6, which functions as an auxiliary tool for accommodating and holding the drug container 1 as shown in FIG. 1 and for moving the drug container 1 downward so as not to rotate, is usually polyethylene or the like. It is made of synthetic resin such as polypropylene, polyester, polyvinyl chloride, polycarbonate, and ABS resin.
And as shown in FIG. 9, it is a tubular member composed of a bottom portion 63, a mouth portion 64, and a body portion 65. The bottom portion 63 is fitted into a spiral groove 51 of the cap 5, which will be described later, and the spiral groove 5
A plurality of first engaging protrusions 61 that move downward along
(In the figure, two are formed in axial symmetry) and the drug container 1
Has a through hole 66 for removing air when it is attached, and the mouth portion 64 is fitted into a longitudinal groove 41 of a guide capsule 4 described later, and a plurality of holes are moved downward along the longitudinal groove 41. Second engaging projections 62 (two are formed at the same position as the first engaging projections 61 in the bottom view in the figure), and the annular projection 6 that holds the drug container 1 so as not to fall off.
8 are formed. The mouth portion 64 may preferably be provided with a plurality of slits 67 to facilitate insertion of the drug container 1. When the cap 5 can be removed, a handle 69 may be provided on the top surface of the vial guide 6, whereby the drug container 1 can be grasped by hand.
Can be easily removed from the guide capsule 3.

A part of the vial guide 6 having the drug container 1 inserted therein is accommodated in the guide capsule 4 together with the double-ended needle 3. The guide capsule 4 is usually a cylindrical container made of the same synthetic resin as that of the vial guide 6, and has open ends and connecting ends at both ends as shown in FIGS. 10 and 11. An annular protrusion 49 for coupling with the cap 5 via the cap removing means 8 shown in FIG. 1 close to the open end side.
Is formed, and a plurality of grooves are formed on the inner wall of the guide capsule 4 so as to extend vertically from the partition wall 48 on the coupling end side toward the open end. The grooves are a plurality of longitudinal grooves 41 that run vertically to the vicinity of the open end (two axially symmetrical grooves are formed in the figure), and a plurality of double-ended needle engagement grooves 44 that are shorter than that (the vertical groove 41 in the figure).
And four are formed in axial symmetry). The longitudinal groove 41 is for engaging with the second engaging protrusion 62 of the vial guide 6 and lowering the vial guide 6 without rotating it. In this embodiment, the double-ended needle 3 has four engaging arms. The double-ended needle engaging groove 44 also serves as the double-headed needle engaging groove 44.
The double-ended needle engaging groove 44 may be provided with a step (not shown) for positioning the double-ended needle 3.

A through hole 46 is formed in the partition wall 48 about the axis, and a cylindrical seal member insertion portion 47 and a coupling portion 43 are concentric with the through hole 46 on the coupling end side of the partition wall 48. It is projected. The through hole 46 is the lower puncture needle 33 of the double-ended needle 3 described later.
The seal member insertion portion 47 is a lower puncture needle of the double-ended needle 3 that is inserted into the through hole 46 and is inserted into the puncture needle guide 26 of the communication port 21 of the dissolution liquid container 2 described later. Three
A seal member 7 for sealing 3 is attached. The sealing member 7 is a cap-shaped member having a through hole smaller than the diameter of the lower puncture needle 33 on the top surface.
As shown in FIG. 7, the seal member insertion portion 47, the puncture needle guide 26, and the partition wall 48 are mounted in the space formed therein.
Further, the coupling portion 43 is a portion that is coupled to the communication port 21 of the dissolution liquid container 2, and in the figure, a female screw 431 is formed on the inner wall thereof, and a male screw 211, which will be described later, formed on the outer wall of the communication port 21. It is designed to be screwed.

The connecting end side of the guide capsule 4 is a partition wall 48.
It is formed in a skirt portion 42 that extends downward and encloses the seal member mounting portion 47 and the coupling portion 43. The skirt portion 42 is not always necessary,
By engaging or coupling with the shoulder portion 27 of the dissolution liquid container 2 (see FIG.
Then, the coupling between the guide capsule 4 and the dissolving liquid container 2 which is engaged with the annular step portion 271 formed on the shoulder portion 27 is strengthened. A fitting protrusion 45 is preferably formed at the lower end of the skirt portion 42 so that the guide capsule 4 does not come off, and is fitted into a fitting groove 28, which will be described later, formed in the communication port 21 of the dissolution liquid container 2. It is supposed to do.

The double-ended needle engaging groove 44 may also serve as the vertical running groove 41 or may be only two separately formed. Further, when the lower puncture needle 33 of the double-ended needle 3 is liquid-tightly inserted into the puncture needle guide 26 of the communication port 21, the seal member mounting portion 47 is not always necessary. Connecting part 4
3 and the communication port 21 of the dissolution liquid container 2 are preferably airtightly coupled by screwing or welding, but the skirt portion 42 and the annular step portion 271 of the dissolution liquid container 2 are airtightly coupled by welding or the like. In this case, they may be joined by fitting or the like. Further, when the cap removing means 8 is not provided, the annular protrusion 49 is unnecessary, and in this case,
Open end of guide capsule 4 and skirt 55 of cap 5
Complementary undercuts may be provided at the lower ends of the respective caps, and the cap 5 may be fitted so as to be rotatable.

The double-ended needle 3 used as the communication means is disposed between the drug container 1 and the solution container 2 as shown in FIG. 1, and is usually made of stainless steel (SUS304 is preferable) or synthetic resin. It consists of a canula and a synthetic resin hub. When importance is attached to sharpness, stainless steel canula is preferable, but a double-ended needle made of synthetic resin is preferable in consideration of disposal problems and integral molding. A hard synthetic resin such as ABS resin or polycarbonate is suitable.

The double-ended needle 3 pierces the rubber stopper 12 of the mouth 11 of the medicine container 1 that has descended, and further descends together with the medicine container 1 to pierce the closing membrane 22 of the communication port 21 of the solution container 2. 5 to 7, so that
An upper puncture needle 32 that pierces the hub 31 and the rubber stopper 12 of the drug container 1, and a closing film 22 of the communication port 21 of the dissolution liquid container 2.
A lower puncture needle 33 for piercing the
An engaging arm 34 that engages with the double-ended needle engaging groove 44 of the guide capsule 4 and suppresses the downward movement of the double-ended needle 3 is provided at the tip of 1. The engaging arm 34 is engaged with the double-ended needle engaging groove 44 at the protruding portion 341 at the tip thereof. The upper puncture needle 32 may be formed sharper than the lower puncture needle 33 so that the rubber stopper 12 of the drug container 1 can be pierced first.
2 is formed on the sharpened cutting edge of the central portion, and the lower puncture needle 33
Is formed on a beveled blade edge, but the shape of the blade edge is not particularly limited. 36 is the upper puncture needle 32 of the drug solution passage 35.
The number of outlets is not particularly limited, although three outlets are formed on the side. Two chemical liquid passages 35 may be formed, and in this case, the chemical liquid can be moved without pressing the dissolving liquid container 2.

The solution container 2 is generally a container that can be pressed and deformed and is made of a relatively soft synthetic resin such as polyethylene, polypropylene or polyester, and has a communication port 21 and a chemical solution outlet 23 at both ends. Communication port 21
Is a mouth for communicating with the drug container 1 via the double-ended needle 3, and as shown in FIGS. 3 and 4, the tip thereof is a pipe-like puncture needle guide 26 for inserting the lower puncture needle 33.
The puncture needle guide 26 is provided with a closed film 22 for sealing the dissolution liquid container 2 at a portion corresponding to the bottom thereof. A male screw 211 is formed on the outer wall of the communication port 21 as a means for coupling with the coupling portion 43 of the guide capsule 4. Shoulder 27 on the side of the communication port 21 of the solution container 2
An annular step portion 271 for engaging with the skirt portion 42 of the guide capsule 4 may be formed therein. Also, the communication port 21
If necessary, a fitting groove 28 for fitting the fitting projection 45 of the guide capsule 4 may be formed on the outer wall of the above.

The solution container 2 contains solutions such as physiological saline, glucose solution, distilled water and electrolyte solution, which are not shown in the drawing. Further, the communication port 21 of the dissolution liquid container 2 is not limited to the shape provided with the puncture needle guide 26 having a closed membrane as the bottom as shown in FIGS. The same closure membrane may be formed in the same shape as that of an ordinary bottle covered with a sealing member including a rubber stopper and a pressing member. However, in this case, the seal member mounting portion 47 of the guide capsule 4 is unnecessary, and the through hole 46 functions as a guide for the lower puncture needle 33.

The chemical solution outlet 23 has the same structure as that of a normal bottle. For example, as shown in FIG. 3, a pressing member 25 and a rubber stopper 24 attached to the pressing member 25 are provided on a closing membrane 231. A structure in which the following sealing member is covered is adopted. Attaching the sealing member to the dissolution liquid container 2 is performed with the chemical liquid outlet 23.
The welding is performed by welding the flange 232 formed on the outer wall of the and the flange 251 formed on the pressing member 25. still,
Although not shown, the rubber plug 24 of the sealing member may be protected by a cover member such as a film so that the surface thereof is not contaminated.

In the infusion solution container of the present invention, the guide capsule 4 is airtightly attached to the solution container 2, the double-ended needle 3 and the mouth 11 side of the drug container 1 are set in the guide capsule 4, and the guide capsule 4 It is completed when the cap 5 is airtightly attached to the open end. In this case, the guide capsule 4 and the double-ended needle 3
A seal member 7 for sealing the lower puncture needle 33 may be attached, and a cap removing means 8 may be used to connect the guide capsule 4 and the cap 5.

The cap 5 has a function of sealing the open end of the guide capsule 4 and moving the drug container 1 downward. Usually, as shown in FIGS. 12 to 14, the same composition as the guide capsule 4 is used. It is made of resin and has a tubular shape. A suspending means 52 is preferably provided on the top surface 57 of the cap 5, and a lower end of a skirt 55 that is a side wall of the suspending means 52 accommodates a sealing member 53 that hermetically seals between the cap 5 and the guide capsule 4. Is formed with a seal member mounting groove 54, and a spiral groove 51 that engages with the first engaging protrusion 61 of the vial guide 6 is formed on the inner wall of the skirt 55.
Are formed. The hanging means 52 may be provided with a hinge part 59 so that it can be folded. When the cap removing means 8 is adopted, a projection 56 that is coupled to the groove of the cap removing means 8 is provided at the lower end of the skirt 55. May be. Reference numeral 58 is a hanging hole.

The spiral groove 51 is provided longitudinally in a spiral shape on the inner wall of the skirt 55, and the first engaging projection 61 and the second engaging projection 62 of the vial guide 6 and the guide capsule 4 are provided. The vertically running groove 41 constitutes a medicine container pressing means. Although not shown, a spirally slanting protrusion may be used instead of the spiral groove 51, and in this case, the first engaging protrusion 61 of the vial guide 6 may contact under the protrusion. Is located in. Although not shown, the drug container pressing means is provided with a vial guide 6 on the cap 5.
Of the guide capsule 4 is formed by forming a protrusion corresponding to the first engaging protrusion 61 of the guide capsule 4, forming a spiral groove corresponding to the spiral groove 51 of the cap 5 on the vial guide 6, and a second engaging protrusion 62. 41 and the first vial guide 6
And a vertical groove corresponding to the vertical groove 41 of the guide capsule 4 is formed, and a protrusion corresponding to the second engaging projection 62 of the vial guide 6 is formed on the guide capsule 4.
A combination with the spiral groove 51 of the cap 5 can also be adopted.

The groove referred to as the spiral groove 51 or the longitudinal groove 41 is
It also includes a gutter-shaped one formed by two protrusions as shown in the drawing, and is not necessarily limited to the groove formed in the inner wall of the cap 5 or the guide capsule 4. Further, as a method of connecting the cap 5 and the guide capsule 4 by the cap removing means 8, for example, screwing, luer connection or other suitable method of releasing the connection when the cap 5 and the guide capsule 4 are rotated in the opposite direction to the connection can be adopted.

FIG. 15 shows a cross section of the essential part of another embodiment of the present invention, in which a stand 9 is provided at the drug solution outlet 23 for making the infusion container self-supporting. The stand 9 includes a leg portion 91 and a fitting portion 92, and the inner wall of the fitting portion 92 is fitted to the outer wall of the pressing member 25. The material of the stand 9 is not limited, but generally metal or synthetic resin is used.

Next, the use of the infusion container of the present invention will be described in detail. When the cap 5 is turned clockwise, the vial guide 6 is prevented from rotating because the second engagement protrusion 62 of the vial guide 6 is fitted into the longitudinal groove 41 of the guide capsule 4, while the first engagement protrusion thereof is blocked. Since 61 is fitted in the spiral groove 51 of the cap 5, it moves downward along the spiral groove 51 together with the drug container 1 held therein.
Then, the rubber stopper 12 of the mouth 11 of the medicine container 1 is replaced by the double-ended needle 3
Punctured by the upper puncture needle 32 of the vial guide 6, the vial guide 6 moves further downward together with the drug container 1 and the double-ended needle 3,
The rubber plug 12 of the drug container 1 is pierced by the upper puncture needle 32 of the above, and the communication port 2 of the solution container 2 is pierced by the lower puncture needle 33.
One closure membrane 22 is pierced. In this way, when the drug container 1 and the solution container 2 are communicated with each other via the double-ended needle 3, the solution container 2 is pressed upward with the solution container 2 facing up.
The dissolved solution inside flows into the drug container 1 and mixes with the dry preparation in the drug container 1 to become a drug solution. Next, with the cap 5 facing upward, the suspending means 52 is hung on a hanger (not shown) or the like, the drug solution in the drug container 1 is returned into the solution container 2 by pumping, and an infusion set or the like is put into the drug solution outlet 23. Infusion treatment can be performed by connecting still,
When the infusion container is to be discarded after use, the cap 5 can be easily removed from the guide capsule 4 by turning the cap removing means 8 counterclockwise. It can be taken out and sorted. It is also possible to make the guide capsule 4 and the solution container 2 removable.

[0027]

As is apparent from the above description, by adopting the infusion container of the present invention, it is easy to operate, hassle-free, and there is no fear that the mixed drug solution leaks. It is possible to provide an infusion container capable of mixing a drug and a solution. Further, since the number of parts is small, it is possible to provide an infusion container at low cost. Further, by providing the cap removing means 8, it is possible to separate and dispose of the waste, and by providing a stand on the dissolution liquid container, the infusion container can be made to stand on its own, so that it does not occupy a lot of space. Can be obtained.

[Brief description of drawings]

FIG. 1 is a cross-sectional view of one embodiment of the infusion container of the present invention.

2 is a cross-sectional view of the drug container of FIG.

FIG. 3 is a cross-sectional view of the solution container of FIG.

FIG. 4 is a plan view of FIG. 3;

5 is a cross-sectional view of the double-ended needle of FIG.

FIG. 6 is a bottom view of FIG.

FIG. 7 is a plan view of FIG.

8 is a cross-sectional view of the vial guide of FIG. 1 provided with a handle.

FIG. 9 is a bottom view of FIG.

10 is a cross-sectional view of the guide capsule of FIG. 1.

11 is a plan view of FIG. 10.

FIG. 12 is a side view of the cap of FIG. 1.

13 is a cross-sectional view taken along line XX of FIG.

14 is a plan view of FIG. 12.

FIG. 15 is a cross-sectional view of main parts of another embodiment.

16 is a cross-sectional view of the stand of FIG.

FIG. 17 is a bottom view of FIG. 16.

[Explanation of symbols]

 1 drug container 2 dissolution liquid container 3 double-headed needle 4 guide capsule 5 cap 6 vial guide 8 cap removing means 9 stand 21 communication port 22 occluding membrane 23 drug solution outlet 26 puncture needle guide 31 hub 32 upper puncture needle 33 lower puncture needle 41 longitudinal running Groove 51 Spiral groove 61 First engagement protrusion 62 Second engagement protrusion 69 Handle

Claims (7)

(57) [Claims] 1. A drug container having a mouth sealed with a rubber stopper,
A solution container made of a synthetic resin that is press-deformable and has a communication port with the drug container and a drug solution outlet at its both ends, and an upper and lower part interposed between the mouth part of the drug container and the communication port of the solution container. A double-ended needle having puncture needles at both ends, a guide capsule having a connecting end of the open end and the outer wall of the communication port of the dissolution liquid container, and a part of the drug container and the double-ended needle to be slidable downward, and The cap comprises a cap that seals the open end of the guide capsule. The cap is rotated by cooperating with the inner wall of the cap, the inner wall of the guide capsule and the outer wall of the drug container to move the drug container downward. When the drug container moves downward without rotating and reaches the double-ended needle, and further moves downward together with the double-headed needle, the rubber stopper at the mouth of the drug container and the sealing member at the communication port of the solution container become both. Pierced by the needle, infusion container drug container and solvent container is so as to be communicated. 2. The medicine container pressing means is provided in a plurality of parallel spiral grooves obliquely running downward to the inner wall of the cap, a plurality of vertically running grooves of the inner wall of the guide capsule, and a bottom portion of the outer wall of the medicine container. 2. A plurality of first engaging projections fitted into the oblique running grooves and a plurality of second engaging projections fitted into the vertical running grooves provided on the shoulder portion of the medicine container. The infusion container described in. 3. Instead of providing an engaging projection on the outer wall of the drug container, a usual drug container is inserted into a vial guide, and the first engaging projection and the second engaging projection are provided on the outer wall of the vial guide. The infusion container according to claim 2, which is provided with a protrusion corresponding to. 4. The infusion container according to claim 1, wherein the cap is provided with suspending means. 5. The infusion container according to claim 1, wherein a stand for making the infusion container self-support is provided at the drug solution outlet of the dissolution liquid container. 6. The infusion container according to claim 1, wherein the guide capsule is provided with a cap removing means. 7. The infusion container according to claim 6, wherein a handle is provided on the top surface of the vial guide so that the vial can be taken out after removing the cap.