JP2010057398A - Culture apparatus - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a culture apparatus maintaining the inside of a culture chamber at a predetermined humidity while inhibiting dew condensation at a place which has the possibility of affecting a cultured product. <P>SOLUTION: The culture apparatus 1 comprises: a thermal insulation casing having a metallic inner box 4 forming a culture chamber 4b mounted with a water-reserving tray 7 for humidifying the inside of the chamber, a metallic outer box 2 covering the inner box 4, a first heater 22 disposed on the outer side of the inner box and heating the inside of the chamber, a first thermal insulation material 21 disposed on the inner side of the outer box, and an opening for the culture chamber; a thermal insulation door having an inner plate, an outer plate, a second heater disposed on the inner side of the inner plate, and a second thermal insulation material disposed on the inner side of the outer plate; and a metallic heat-radiating member 100 joined to the bottom plates of the inner and outer boxes in between them, and transmitting heat at a specific portion of the bottom plate of the inner box corresponding to the relevant portion of the culture chamber, to the bottom plate of the outer box so that the temperature at a specific portion of the bottom surface of the culture chamber is lower than those at the other portions when the opening is closed. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a culture apparatus.

  There is a culture apparatus for culturing a culture such as cells and microorganisms in a culture chamber. The culture apparatus includes a heater for heating the culture chamber in which the water storage tray is placed. For example, the culture chamber is controlled to maintain the culture chamber at a predetermined temperature, and the chamber is maintained at the predetermined temperature. It is designed to maintain a predetermined humidity. However, since the humidity in the culture chamber is generally close to the saturated water vapor density, even if the temperature fluctuates slightly, there is a risk that the water vapor in the same chamber may shift from a saturated state to a supersaturated state.

In contrast, for example, a heater for heating the water in the water storage tray and a heater for heating the culture chamber other than the water storage tray are provided, and the water in the water storage tray is controlled by individually controlling these two types of heaters. Is maintained at a temperature lower than the temperature in the culture chamber, thereby returning the supersaturated water in the culture chamber to the water storage tray to suppress dew condensation (see, for example, Patent Document 1). The culture apparatus further includes a temperature sensor for detecting the temperature of the water in the water storage tray and a temperature sensor for detecting the temperature in the culture chamber. Based on the detection results of these two temperature sensors, Two types of heaters are individually controlled.
Japanese Patent Laid-Open No. 5-227742

  By the way, since the action of the heater is not only cooling but heating only, the temperature of the water in the water storage tray and the temperature in the culture chamber are determined by controlling only the heater as in the culture apparatus disclosed in Patent Document 1 described above. In order to maintain this relationship, for example, a corresponding detection accuracy is required for each temperature sensor. Here, the predetermined relationship between the two temperatures means that the water storage tray can be kept at a humidity close to the saturated water vapor density while suppressing condensation in a place that may affect the culture in the culture room. The temperature of the water is lower than the temperature in the culture chamber. However, in order to realize this, the culture apparatus requires a temperature sensor with high detection accuracy, for example, and thus there is a problem that the manufacturing cost increases.

  On the other hand, because the temperature of the water in the water storage tray and the temperature in the culture chamber cannot be maintained in the predetermined relationship described above, for example, when condensation occurs near the culture, germs are generated in the condensed water, The problem of adversely affecting the culture arises. Alternatively, since the temperature of the water in the water storage tray and the temperature in the culture chamber cannot be maintained in the predetermined relationship described above, for example, when the humidity in the culture chamber is significantly lower than the saturated water vapor density, the culture apparatus originally maintains high humidity. There arises a problem that the performance of the system deteriorates.

  The invention for solving the above-mentioned problems is made of a metal inner box that forms a culture chamber on which a water storage tray for humidifying the room when the culture is cultured, and a metal cover that covers the inner box. A heat insulating housing having an outer box, a first heater disposed outside the inner box and heating the culture chamber, a first heat insulating material disposed inside the outer box, and an opening of the culture chamber A body, an inner plate, an outer plate, a second heater that is disposed inside the inner plate and heats the culture chamber, and a second heat insulating material disposed inside the outer plate, The heat insulating door that seals the opening, and the bottom plate of the inner box and the bottom plate of the outer box are joined to the bottom plate of the inner box and the bottom plate of the outer box, and the culture chamber when the opening is sealed Corresponding to the specific part of the bottom of the culture chamber so that the temperature of the specific part of the bottom is lower than the temperature of the other part of the culture chamber. It is a culture apparatus characterized by comprising a metallic heat radiating member for transferring heat of a specific portion of the bottom plate of the inner box to the bottom plate of the outer box.

  ADVANTAGE OF THE INVENTION According to this invention, the chamber can be maintained at predetermined humidity, suppressing the dew condensation in the place which may affect the culture in a culture chamber.

=== Culture equipment ===
A configuration example of the culture apparatus 1 of the present embodiment will be described with reference to FIGS. 1 and 2. 1 is a front cross-sectional view of an example of the culture apparatus 1 of the present embodiment, and FIG. 2 is a side cross-sectional view taken along the line AA ′ of the culture apparatus 1 of FIG. Here, FIG. 1 shows a cross section taken along line BB ′ of FIG.

  The culture apparatus 1 includes an inner box 4, an outer box 2, heaters 22 and 23 (first heater), a heat insulating material 21 (first heat insulating material), a heat insulating casing having an opening on the front side (+ Y side), A door (heat insulating door) 3 and a heat radiating member 100 are provided.

  The inner box 4 is a substantially rectangular parallelepiped box made of, for example, stainless steel, in which the culture chamber 4 b is formed, and the outer box 2 is a box made of, for example, stainless steel and substantially similar to the inner box 4. In the culture chamber 4b, for example, cultures such as cells and microorganisms are cultured.

  The heaters 22 and 23 are disposed outside the inner box 4 to heat the inside of the culture chamber 4b. Here, the heater 22 is disposed outside the side plate (± X side plate), back plate (−Y side plate), and top plate (+ Z side plate) of the inner box 4. In addition, the heater 23 is disposed around a heat radiating member 100 described later outside the bottom plate 4c (−Z side plate) of the inner box 4 to heat the inside of the culture chamber 4b and in the humidifying tray (water storage tray) 7. Heat the water.

  The heat insulating material 21 is disposed inside the outer box 2 to keep the inside of the heat insulating material 21 warm. Note that an air jacket 6 as an air circulation path, for example, is formed between the heat insulating material 21 and the inner box 4 in order to further keep the inner box 4 warm. Arranged in the jacket 6.

  Both the inner box 4 and the outer box 2 have an opening on the front side. An inner door 4a is provided at the opening of the inner box 4 so as to be opened and closed via a predetermined hinge (not shown). The inner door 4a is made of, for example, tempered glass and has a flat plate shape. When the inner door 4a is closed with a packing (not shown) with respect to the opening of the inner box 4, the inside of the inner box 4 is sealed.

  The outer door 3 is a door made of, for example, metal and having a flat plate shape having an inner plate 32, an outer plate 31, a heater 34 (second heater), and a heat insulating material 33 (second heat insulating material). The two openings can be opened and closed via a predetermined hinge (not shown). Here, the inner plate 32 has a convex portion 32a at a position facing the opening of the outer box 2 on the outer side surface, and a packing 35 for sealing the inside of the outer box 2 is further provided on the convex portion 32a. It is attached. The outer plate 31 has a control panel (not shown) on its outer surface, and this control panel includes, for example, keys (not shown) for setting the temperature, humidity, etc. in the culture chamber 4b and their current values. It has a display (not shown) for displaying values. The heater 34 is disposed inside the inner plate 32 to heat the inside of the culture chamber 4 b, and the heat insulating material 33 is disposed inside the outer plate 31 to keep the inside of the heat insulating material 33 warm.

  The heat radiating member 100 is made of metal that is joined to both the bottom plate 4c portion of the inner box 4 and the bottom plate 2c of the outer box 2 that substantially correspond to the portion on the bottom surface of the culture chamber 4b where the humidifying tray 7 is placed. It is a member. In addition, only the schematic structure is illustrated for the heat radiating member 100 in FIG.1 and FIG.2 for convenience of illustration. The heat radiating member 100 illustrated in the figure is configured by combining a bent plate 101, a heat radiating plate 103, a reinforcing plate 102, and a support plate 105, which will be described later.

  The back plate of the inner box 4 and the wall plate 5 made of stainless steel, for example, constitute a duct 52 for forming an air passage for air. A fan 51 (sirocco fan) is provided on the upper side (+ Z side) in the duct 52.

  When the culture is cultured in the culture chamber 4b, the air on the upper side of the culture chamber 4b flows into the duct 52 through the suction port 5a due to the rotation of the fan 51 in a certain direction, and the inside of the duct 52 from the upper side to the lower side ( -Z side) and flows out from the outlet 5b. The air from the discharge port 5b is humidified with the water in the humidifying tray 7, then passes through the hole 8a on the front side of the cover 8, flows from the lower side to the upper side in the culture chamber 4b, and then the suction port again. It returns to 5a. By such air circulation, the inside of the culture chamber 4b is maintained at, for example, a substantially uniform temperature and humidity. In FIG. 1, the cover 8 is omitted for convenience of illustration.

On the other hand, when the inside of the culture chamber 4b is sterilized, the humidifying tray 7 and the cover 8 are removed from the bottom surface of the culture chamber 4b, a predetermined gas generator (not shown) is placed, and hydrogen peroxide (H ₂ O ₂ ) is placed on this. ) The fan 51 in the duct 52 is rotated in a certain direction while generating gas. Thereby, hydrogen peroxide gas circulates with air in the culture chamber 4b, and the inner surface and the like of the chamber 4b are sterilized. The gas generator includes, for example, a tank (not shown) for storing hydrogen peroxide (an aqueous solution in which hydrogen peroxide is dissolved) and an ultrasonic vibrator for atomizing the hydrogen peroxide in the tank. (Not shown).

  As illustrated in FIG. 2, the culture device 1 includes a fan 110 (exhaust device) inside the back plate of the outer box 2 and below the heat insulating material 21, and the back plate facing the fan 110. Is provided with an air exhaust port 2d (exhaust device). The fan 110 allows the air in the space 100a to flow so that the temperature of the space 100a between the heat insulating material 21 below the bottom plate 4c of the inner box 4 and the bottom plate 2c of the outer box 2 is lower than the temperature of the culture chamber 4b. Exhaust. That is, the fan 110 cools, for example, the heat radiating plate 103 exposed to the outer box 2 side of the heat insulating material 21 or the bottom plate 2c of the outer box 2 by forming an air flow in the space 100a. The heat release of the portion of the bottom plate 4c substantially corresponding to the portion on which the humidifying tray 7 is placed is promoted.

=== Heat dissipation member ===
Details of the heat dissipation member 100 will be described with reference to FIGS. 1 to 3. FIG. 3 is an enlarged view of a cross section of the heat dissipation member 100 of FIG.

  The portion on the bottom surface of the culture chamber 4b where the humidifying tray 7 is placed has a substantially rectangular shape when viewed from the upper side (+ Z side) (FIGS. 1 and 2). In the illustration of FIG. 2, the part (specific part) of the bottom plate 4 c corresponding to a part (specific part) on the front side (+ Y side) of the culture chamber 4 b among the substantially rectangular part on which the humidifying tray 7 is placed. The heat radiating member 100 with the heat radiating plate 103 is joined, and the heater 23 is disposed in the portion of the bottom plate 4c corresponding to the remaining part on the back side (−Y side) of the same chamber 4b. . Moreover, in the illustration of FIG. 2, the part (specific part) which protruded from the part in which the humidification tray 7 is mounted in the bottom face of the culture chamber 4b to the front side also corresponds to the part (specific part) of the bottom plate 4c corresponding to this. The heat radiating member 100 without the heat radiating plate 103 is joined.

  In the illustration of FIG. 3, the heat radiating member 100 includes a bent plate (first heat radiating member) 101, a heat radiating plate (first heat radiating member) 103, a reinforcing plate (first heat radiating member) 102, and a support plate (second A heat dissipating member) 105. The heat radiating member 100 includes a member 104 (second heat radiating member) and a member 106 (first heat radiating member).

  The bent plate 101 includes a bonding plate 101a bonded to the above-described specific portion of the bottom plate 4c, and the bottom plate 4c is based on both ends (± X side ends) of the bonding plate 101a so that the heat insulating material 21 is placed. For example, stainless steel plates that are bent perpendicularly to each other (V in FIG. 3) and bent in parallel to the bottom plate 4c (in the X-axis direction) and spaced apart from each other (H in FIG. 3). The heat insulating material 21 placed on the bent plate 101 surrounds the heat radiating member 100 in parallel with the bottom plate 4c, and the air jacket described above is formed between the heat insulating material 21 and the bottom plate 4c. 6 is provided with a heater 23. By this bent plate 101, the heat of the specific part mentioned above joined to the joining plate 101a is transmitted to the outer box 2 side of the heat insulating material 21.

  The heat radiating plate 103 is a pair of aluminum plates joined to the surface of the bent plate 101 on the outer box 2 side. Each of the pair of heat radiating plates 103 has a shape similar to the bent shape of the bent plate 101, and by this shape, the convex portion on the outer box 2 side of the reinforcing plate 102 described later and the bent plate 101 is joined to a portion V bent vertically to the bottom plate 4c and a portion H bent parallel to the bottom plate 4c of the bent plate 101. Moreover, in the illustration of FIG. 2, the dimension of the heat sink 103 in the depth direction (Y-axis direction) of the culture chamber 4b is shorter than the dimension of the joining plate 101a in the same direction. That is, the heat radiating plate 103 has a size and a shape to be joined only to a portion corresponding to a portion on which the humidifying tray 7 is placed on the surface of the bent plate 101 on the outer box 2 side. The heat sink 103 made of aluminum, which has higher heat conductivity than stainless steel or the like, the joint plate of the bent plate 101 with respect to the portion of the bottom plate 4c corresponding to the portion where the humidifying tray 7 is placed among the specific portions described above. Heat transfer from 101a to the outer box 2 side of the heat insulating material 21 is promoted.

  The reinforcing plate 102 is an uneven type, for example, stainless steel plate that is sandwiched between the joining plate 101a and the heat radiating plate 103 and reinforces the bottom plate 4c. In the illustration of FIG. 2, the reinforcing plate 102 is a member narrow in the depth direction of the culture chamber 4b, and a plurality of the reinforcing plates 102 are arranged side by side in the same direction below the joining plate 101a. The reinforcing plate 102 reinforces the bottom plate 4 c and transmits heat of the joining plate 101 a to the heat radiating plate 103.

  The support plate 105 is joined to the surface on the outer box 2 side of the portion parallel to the bottom plate 4c of the heat radiating plate 103 and the bottom plate 2c of the outer box 2, and the bent plate 101, the heat radiating plate 103, and the reinforcing plate 102 are A pair of stainless steel plates for transferring heat to the bottom plate 2 c of the outer box 2. Each of the pair of support plates 105 has a shape bent into a portion parallel to the bottom plate 4c, a portion perpendicular to the bottom plate 4c, and a portion parallel to the bottom plate 2c. That is, a part parallel to the bottom plate 4c of the heat radiating plate 103 is placed on the upper surface of the support plate 105, whereby the bent plate 101, the heat radiating plate 103, the reinforcing plate 102, and the support plate 105 are connected to the inner box 4. The support | pillar which supports between the bottom plate 4c of this and the bottom plate 2c of the outer case 2 is formed. In the illustration of FIG. 2, the dimension of the support plate 105 in the depth direction of the culture chamber 4 b is equal to the dimension of the bent plate 101 in the same direction.

  The heat of the specific part is finally released to the outside of the outer box 2 through the support plate 105, so that the temperature of the specific part is the temperature of the other part in the sealed culture chamber 4b. Can be kept lower. That is, if dew condensation occurs, it occurs only at this specific portion of the bottom surface of the culture chamber 4b, so that this dew condensation is less likely to affect the culture. That is, the humidity in the chamber 4b is close to the saturated water vapor density while suppressing dew condensation in a place that may affect the culture in the culture chamber 4b (for example, the ceiling surface of the culture chamber 4b or the inner side of the inner door 4a). Therefore, the temperature of this specific part can be kept lower than the temperature of the other part in the culture chamber 4b. Note that the ability to maintain the temperature of a specific portion lower than the temperature of other portions in the sealed culture chamber 4b is also useful when hydrogen peroxide gas becomes supersaturated during sterilization in the chamber 4b. is there. That is, if dew condensation of hydrogen peroxide gas occurs, it occurs only at this specific portion of the bottom surface of the culture chamber 4b, so that it can be easily wiped off after the sterilization treatment.

  Moreover, since heat transfer from the bent plate 101 to the support plate 105 is promoted by the heat radiating plate 103 with respect to the portion of the bottom plate 4c corresponding to the portion where the humidifying tray 7 is placed among the specific portions described above, The portion where the humidifying tray 7 is placed can be maintained at the lowest temperature in the sealed culture chamber 4b. Therefore, if condensation occurs, it will return to the water in the humidifying tray 7, so that the influence of this condensation on the culture can be further suppressed. In this embodiment, by setting the area of the part of the bottom plate 4c corresponding to the part where the humidifying tray 7 is placed among the specific parts, for example, to 20% or less of the total area of the bottom plate 4c, Condensation is more concentrated in the humidifying tray 7.

  The member 104 is joined to a portion parallel to the bottom plate 4 c of the pair of heat radiating plates 103 and a portion perpendicular to the bottom plate 4 c of the pair of support plates 105 in order to release heat from the heat radiating plate 103 to the support plate 105. A pair of, for example, stainless steel plates. This member 104 also forms a column supporting the space between the bottom plate 4c of the inner box 4 and the bottom plate 2c of the outer box 2 together with the bent plate 101, the heat radiating plate 103, the reinforcing plate 102, and the support plate 105 described above.

  The member 106 is joined to a portion perpendicular to the bottom plate 4c of the pair of heat radiating plates 103 in order to place the heat insulating material 21 directly under the reinforcing plate 102, and is parallel to the bottom plate 4c from this portion so as to approach each other. (H ′ in FIG. 3) is a pair of bent plates made of, for example, stainless steel. This member 106 also functions to radiate heat from a portion perpendicular to the bottom plate 4c from a surface of the portion parallel to the bottom plate 4c on the outer box 2 side.

  In the illustration of FIG. 3, a screw hole (not shown) is formed in the convex portion on the outer box 2 side of the reinforcing plate 102, and a hole (not shown) is formed in a portion joining the convex portion of the heat radiating plate 103. The radiator plate 103 and the reinforcing plate 102 are joined via screws 102a.

  Further, screw holes (not shown) are formed in the member 106 at portions of the bent plate 101, the heat radiating plate 103, and the member 106 that are perpendicular to the bottom plate 4 c that are joined to each other. Holes (not shown) are respectively formed, and the bent plate 101, the heat radiating plate 103, and the member 106 are joined via screws 106a.

  As described above, the heat radiating member 100 is composed of two heat radiating members including the first heat radiating member (the bent plate 101, the heat radiating plate 103, the reinforcing plate 102, the member 106) and the second heat radiating member (the support plate 105, the member 104). Thus, even when the heat insulating material 21 is disposed between the bottom plate 4c of the inner box 4 and the bottom plate 2c of the outer box 2 while having a gap with both the bottom plates 4c, 2c, a specific portion of the bottom plate 4c Can be efficiently transferred to the bottom plate 2c. That is, first, heat of a specific portion of the bottom plate 4c can be transferred from the inner box 4 side of the heat insulating material 21 to the outer box 2 side by the first heat radiating member, and then the heat of the first heat radiating member is transferred to the second heat radiating member. It can be transmitted to the bottom plate 2c by the member.

  In addition, the temperature of the specific part of the bottom face of the culture chamber 4b depends on the temperature of the space 100a below the heat insulating material 21 to which the heat is released and the temperature of the atmosphere around the culture apparatus 1. That is, as the temperature of the atmosphere increases, the temperature difference between the inside of the culture chamber 4b and the space 100a becomes smaller, so that the temperature of the specific part is less likely to fall to a desired level. In this case, by driving the fan 110 described above, the air in the space 100a is exhausted to generate an air current so that the temperature of the space 100a is lower than the temperature of the culture chamber 4b. Thereby, the temperature of a specific part becomes easy to fall. The fan 110 may be constantly driven or, for example, when the temperature around the space 100a or the culture apparatus 1 measured by a predetermined temperature sensor (not shown) is equal to or higher than the predetermined temperature. May be driven only. However, the present invention is not limited to this. For example, when the culture apparatus 1 is used in an environment where the temperature of the atmosphere is sufficiently low, the culture apparatus 1 may not include such a fan 110.

=== Other Embodiments ===
The above-described embodiments are intended to facilitate understanding of the present invention, and are not intended to limit the present invention. The present invention can be changed and improved without departing from the gist thereof, and the present invention includes equivalents thereof.

  In the above-described embodiment, the bent plate 101 is bent so as to be bent perpendicularly to the bottom plate 4c (V in FIG. 3) from both ends of the joining plate 101a, and parallel to the bottom plate 4c and spaced apart from each other. However, the present invention is not limited to this.

  For example, the member 106 is formed integrally with the bent plate 101, and a pair of portions (H ′ in FIG. 3) that are parallel to the bottom plate 4 c and approach each other in the member 106 have the heat insulating material 21 directly below the reinforcing plate 102. It may be placed.

  Further, for example, the pair of portions parallel to the bottom plate 4c of the bent plate 101 may be bent in a direction away from each other, depending on the position in the depth direction (Y-axis direction in FIG. 2) of the culture chamber 4b. It may be bent in the approaching direction. As an example, among the above-described specific portions of the bottom surface of the culture chamber 4b, the portion on which the humidifying tray 7 is placed (the portion on the -Y side in FIG. 2) of the folding plate 101 may be as follows. A pair of portions parallel to the bottom plate 4c bend in a direction away from each other (corresponding to H in FIG. 3). On the other hand, of the above-described specific portion on the bottom surface of the culture chamber 4b, the bottom plate of the bent plate 101 is the portion protruding from the portion where the humidifying tray 7 is placed to the front side in the depth direction (the portion on the + Y side in FIG. 2). A pair of portions parallel to 4c bend in a direction approaching each other (corresponding to H ′ in FIG. 3).

It is front sectional drawing of an example of the culture apparatus of this Embodiment. It is side surface sectional drawing in A-A 'of the culture apparatus of FIG. It is an enlarged view of the cross section of the heat radiating member of FIG.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Culture apparatus 2 Outer box 2c Bottom plate 2d Exhaust port 3 Outer door 4 Inner box 4a Inner door 4b Incubation chamber 4c Bottom plate 5 Wall plate 5a Intake port 5b Outlet port 6 Air jacket 7 Humidifying tray 8 Cover 8a Hole 21 Insulating material 22, 23 Heater 31 Outer plate 32 Inner plate 32a Protruding portion 33 Heat insulating material 34 Heater 35 Packing 51 Fan 52 Duct 100 Heat radiation member 100a Space 101 Bent plate 101a Joining plate 102 Reinforcement plate 102a Screw 103 Heat radiation plate 104 Member 105 Support plate 106 Member 110 Fan

Claims (8)

A metal inner box that forms a culture chamber on which a water storage tray for humidifying the room when culturing the culture is placed, a metal outer box that covers the inner box, and an outer side of the inner box A heat-insulating housing having a first heater disposed and heating the culture chamber, a first heat insulating material disposed inside the outer box, and an opening of the culture chamber;
An inner plate, an outer plate, a second heater disposed inside the inner plate and heating the culture chamber, and a second heat insulating material disposed inside the outer plate, and the opening An insulated door that seals,
The temperature of a specific part of the bottom surface of the culture chamber when the opening is sealed between the bottom plate of the inner box and the bottom plate of the outer box is joined between the bottom plate of the inner box and the bottom plate of the outer box. A metal heat dissipating member that transmits heat of a specific part of the bottom plate of the inner box corresponding to a specific part of the bottom of the culture chamber to the bottom plate of the outer box, so as to be lower than the temperature of the other part of the chamber,
A culture apparatus comprising:   The heat radiating member is joined to a specific portion of the bottom plate of the inner box, and transmits heat of the specific portion from the inner box side to the outer box side of the first heat insulating material, and the outer box. The culture apparatus according to claim 1, further comprising: a second heat radiating member that is joined to the bottom plate and transmits heat of the first heat radiating member to the bottom plate of the outer box.   The said 1st heat radiating member has an aluminum heat radiating plate which transmits the heat | fever of the specific part of the bottom plate of the said inner box, The said 2nd heat radiating member is joined to the said heat radiating plate, The said heat radiating member is joined. 2. The culture apparatus according to 2. The first heat radiating member includes a joining plate joined to a specific portion of the bottom plate of the inner box, and the bottom plate of the inner box is based on an end of the joining plate so that the first heat insulating material is placed. A folding plate that bends in a direction substantially perpendicular to the inner box and bends in a direction that is substantially parallel to the bottom plate of the inner box, and an aluminum heat dissipation plate that is joined to the outer box side surface of the bending plate; Have
The culture apparatus according to claim 2, wherein the second heat radiating member is joined to the heat radiating plate.   The culture apparatus according to claim 4, wherein the first heat radiating member further includes an uneven reinforcing plate that is sandwiched between the joining plate and the heat radiating plate and reinforces a bottom plate of the inner box. A part of the heat radiating plate substantially parallel to the bottom plate of the inner box is placed on the upper surface of the second heat radiating member,
The culture apparatus according to claim 4 or 5, wherein the first heat radiating member and the second heat radiating member form a support column that supports a space between a bottom plate of the inner box and a bottom plate of the outer box.   The culture device according to any one of claims 1 to 6, wherein the specific portion of the bottom surface of the culture chamber is a portion on which the water storage tray is placed.   An exhaust device that exhausts the air in the space so that the temperature of the space between the first heat insulating material disposed inside the bottom plate of the outer box and the bottom plate of the outer box is lower than the temperature of the culture chamber. The culture apparatus according to any one of claims 1 to 7, further comprising:

Images