JP2009050464A - Needle-integrated measuring device - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a needle-integrated measuring device capable of achieving electric conduction between a biosensor chip and the measuring device by a simple structure, when a puncture device and the biosensor chip are simultaneously driven for puncture and sample collection. <P>SOLUTION: The needle-integrated measuring device 10 includes a connector 32 to which a biosensor cartridge 11 integrated with a puncture needle 13 and the biosensor chip 20 is detachably attached; a drive mechanism 31 to drive the connector 32 to a measuring device body 40 for puncture; a moving electrode 39 to be electrically conductive to the biosensor chip 20 of the biosensor cartridge 11 when the cartridge is attached; and a fixed electrode 41 provided at the measuring device body 40 to be brought into contact with the moving electrode 39 at least after the puncture of the puncture needle 13 to make the biosensor chip 20 electrically conductive to the measuring device 30. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a needle-integrated measuring apparatus, for example, a needle-integrated measuring apparatus that performs chemical substance measurement and analysis using a reagent contained in a biosensor chip.

Conventionally, a biosensor in which a biosensor chip and a lancet are integrated has been disclosed (see, for example, Patent Document 1).
5A is a perspective view of the biosensor described in Patent Document 1, and FIG. 5B is an exploded perspective view of the biosensor.

  As shown in FIG. 5, the lancet-integrated biosensor 100 includes a chip body 101, a lancet 103, and a protective cover 105. The chip body 101 has a cover 101a and a substrate 101b that can be opened and closed, and an internal space 102 is formed on the inner surface of the cover 101a. The internal space 102 has a shape that can accommodate the lancet 103 in a movable manner.

The needle 104 provided at the tip of the lancet 103 can be moved in and out from an opening 102 a formed at the front end of the internal space 102 of the chip body 101 as the lancet 103 moves.
The shape of the internal space 101a is curved so that the width of the inner space 101a is slightly narrower than that of the lancet 103 at the end where the protrusion 103a is located. It is like that.

The protective cover 105 has a tube part 105 a into which the needle 104 is inserted, and the tube part 105 a can be accommodated inside the chip body 101 as the needle 104 moves.
Therefore, in a state before use, the protective cover 105 is put on the needle 104 to protect the needle 104 and prevent the user from being accidentally injured. Note that the substrate 101b is provided with a pair of electrode terminals 106 so that it can be electrically connected to a measuring apparatus (not shown).

  In use, the protective cover 105 is removed and the lancet 103 is pushed to cause the needle 104 to protrude from the chip body 101. After puncturing the subject in this state, the needle 104 is housed inside the chip main body 101, and the opening 102a provided at the front end of the chip main body 101 is brought close to the puncture port of the subject to collect outflowed blood. .

  Incidentally, the lancet-integrated biosensor 100 described in Patent Document 1 has a structure in which the lancet 103 moves in the internal space 102 of the chip body 101, and the structure is complicated. For this reason, there are inconveniences that the production is troublesome and the biosensor 100 is increased in size and the production cost is increased.

Therefore, a biosensor chip having a simple structure and a reduced size has been devised by providing the puncture needle integrally with the chip body so that the puncture needle protrudes from the tip of the chip body (for example, Patent Document 2).
WO02-056769 JP 2007-155622 A

  However, in the measuring device using the needle-integrated biosensor chip described in Patent Document 2 described above attached to the tip, the biosensor chip moves forward with respect to the measuring device at the time of puncturing and sampling. Therefore, it is necessary to ensure electrical continuity between the biosensor chip and the measuring device after the biosensor chip moves forward and collects the sample.

  The present invention has been made in view of the above-described problems, and when the puncture tool and the biosensor chip are simultaneously driven to perform puncture and sample collection, the biosensor chip and the measurement device can be easily configured. An object of the present invention is to provide a needle-integrated measuring apparatus that can achieve electrical conduction.

The above-mentioned object according to the present invention is a connector to which a biosensor cartridge integrally including a puncture device and a biosensor chip is detachably mounted,
A drive mechanism for driving the connector to puncture the measurement apparatus body;
A moving electrode provided in the connector and electrically conducting with the biosensor chip of the biosensor cartridge when the cartridge is mounted;
A fixed electrode that is provided in the measuring device main body and at least contacts the moving electrode after puncturing the puncture device to electrically connect the biosensor chip and the measuring device;
This is achieved by a needle-integrated measuring apparatus characterized by comprising:

According to the needle-integrated measuring apparatus having the above configuration, when the biosensor cartridge is attached to the connector, the biosensor chip is electrically connected to the moving electrode of the connector. Since the moving electrode comes into contact with the fixed electrode and is electrically conductive, the biosensor chip is electrically connected to the measuring device.
Therefore, information on the collected sample can be transmitted from the biosensor chip to the measurement device while driving the biosensor cartridge via the connector to perform puncture and sample collection.

In the needle-integrated measuring apparatus having the above-described configuration, it is preferable that the fixed electrode extends along the movement locus of the moving electrode.
According to the needle-integrated measuring apparatus having such a configuration, the fixed electrode is formed along the movement locus of the moving electrode, that is, along the moving range, and the moving electrode maintains a contact state with the fixed electrode at an arbitrary moving position. . Therefore, the moving electrode and the fixed electrode are not intermittently contacted, and the contact is always stable and electrical connection reliability is increased.

In the needle-integrated measuring apparatus having the above-described configuration, it is preferable that the fixed electrode is disposed at a position where it comes into contact with the moving electrode at least after puncturing the puncture device.
According to the needle-integrated measuring apparatus having such a configuration, the moving electrode and the fixed electrode come into contact only after necessary puncturing, and wear due to sliding of the moving electrode and the fixed electrode can be reduced. Further, the manufacturing cost can be reduced by reducing the formation area of the fixed electrode.

In the needle-integrated measuring apparatus having the above-described configuration, it is preferable that the fixed electrode is disposed at a position in contact with the moving electrode before and after puncturing the puncture device.
According to the needle-integrated measuring apparatus having such a configuration, the moving electrode and the fixed electrode are in contact with each other only before and after the necessary puncturing, and wear due to sliding of the moving electrode and the fixed electrode can be reduced. In addition, since the moving electrode comes into contact with the fixed electrode even before the puncture device is punctured, the biosensor cartridge mounted on the connector can be detected, and the operation of the biosensor chip and the mounted state can be confirmed.

In the needle-integrated measurement apparatus having the above-described configuration, it is preferable that at least one of the moving electrode and the fixed electrode is formed of an elastic contact terminal that can be elastically displaced in a contact direction.
According to the needle integrated type measuring apparatus having such a configuration, the moving electrode and the fixed electrode are in stable contact, and the electrical connection reliability is increased.

  According to the needle-integrated measuring apparatus according to the present invention, the moving electrode provided in the connector and conducted to the biosensor chip, and the moving electrode provided in the measuring apparatus main body and in contact with the moving electrode after puncturing of the puncture tool are measured. Since the fixed electrode that electrically connects the device is provided, when the puncture tool and the biosensor chip are simultaneously driven to perform puncture and sample collection, the electrical connection between the biosensor chip and the measurement device can be achieved with a simple structure. Continuity can be achieved.

Hereinafter, preferred embodiments of a needle-integrated measuring apparatus according to the present invention will be described in detail with reference to the accompanying drawings.
It should be understood that the embodiments disclosed herein are illustrative in all respects and are not restrictive. The scope of the present invention is defined by the terms of the claims, rather than the meanings described below, and is intended to include any modifications within the scope and meaning equivalent to the terms of the claims.

FIG. 1 is a configuration diagram of a needle integrated measuring apparatus according to a first embodiment of the present invention.
As shown in FIG. 1, a biosensor cartridge 11 integrally including a puncture needle 13 and a biosensor chip 20 as a puncture tool for puncturing a subject M is attached to and detached from the needle-integrated measurement apparatus 10 according to the present embodiment. A connector 32 that can be mounted, a drive mechanism 31 that drives the connector 32 to puncture the measurement apparatus main body 40, and an electrical connection with the biosensor chip 20 of the biosensor cartridge 11 when the cartridge 32 is mounted. And a pair of moving electrodes 39, 39 which are electrically connected to each other, and are extended to the measuring device main body 40 along the movement trajectory (vertical direction in FIG. 1) of the moving electrode 39, and come into contact with the moving electrodes 39, 39, respectively. 20 and fixed electrodes 41 and 41 for electrically connecting the measuring apparatus 10 to each other.

  In this embodiment, examples of the puncture device include a hollow injection needle, a lancet needle, a cannula, and the like. These needles may be fixed to resin, or may be integrated with resin (the needle itself is also molded with resin). In the present embodiment, as an example of a puncture device, a lancet needle fixed to a resin is illustrated.

2A and 2B show an example of a biosensor chip 20 in which the puncture needle 13 is provided integrally.
The biosensor chip 20 includes a chip body 21 having two substrates 22a and 22b facing each other and a spacer layer 23 sandwiched between the two substrates 22a and 22b. 13 is fixed between the two substrates 22a and 22b.

Detection electrodes 24a and 24b are provided on the surface of at least one substrate 22a of the two substrates 22a and 22b on the spacer layer 23 side, and tip portions (lower ends in FIG. 2A) are mutually connected. It is bent in an L shape in the opposite direction to maintain a predetermined interval.
At the rear end 21b of the chip body 21, the substrate 22a extends beyond the substrate 22b and the spacer layer 23, and the detection electrodes 24a and 24b are exposed on the substrate 22a.

A hollow reaction portion 25 is formed by the two substrates 22a and 22b and the spacer layer 23 from the tip portion 21a of the chip body 21 to a portion where the two detection electrodes 24a and 24b are opposed to each other.
At the tip of the hollow reaction part 25, a sample collection port 25a for introducing blood as a sample collected by puncturing the specimen with the puncture needle 13 into the hollow reaction part 25 is provided. The sample collection port 25a is provided close to the puncture needle 13, so that even a small amount of sample can be reliably collected, and the burden on the user can be reduced.

In the hollow reaction part 25, the detection electrodes 24a and 24b are exposed, and for example, an enzyme and a mediator are immobilized and reacted with glucose in the blood immediately above or in the vicinity of the detection electrodes 24a and 24b in the hollow reaction part 25. A reagent 26 for generating an electric current is provided.
Accordingly, the hollow reaction part 25 is a part where blood such as blood collected from the sample collection port 25a undergoes a biochemical reaction with the reagent 26.

  As the material of the substrates 22a and 22b and the spacer layer 23, an insulating material film is selected. As the insulating material, ceramics, glass, paper, biodegradable material (for example, polylactic acid microorganism-producing polyester), poly Examples thereof include thermoplastic resins such as vinyl chloride, polypropylene, polystyrene, polycarbonate, acrylic resin, polybutylene terephthalate and polyethylene terephthalate (PET), thermosetting resins such as epoxy resins, and plastic materials such as UV curable resins. A plastic material such as polyethylene terephthalate is preferable because of its mechanical strength, flexibility, and ease of chip fabrication and processing. Representative PET resins include Melinex and Tetron (trade names, manufactured by Teijin DuPont Films, Inc.), Lumirror (trade names, manufactured by Toray Industries, Inc.), and the like.

  Examples of the reagent 26 include enzymes such as glucose oxidase (GOD), glycolose dehydrogenase (GDH), cholesterol oxidase and urigase, and electron acceptors such as potassium ferricyanide, ferrocene and benzoquinone. In consideration of the blood sampling burden of the specimen, the volume of the hollow reaction part 25 is preferably 1 μL (microliter) or less, and particularly preferably 300 nL (nanoliter) or less. With such a minute hollow reaction part 25, a sufficient blood volume of the specimen can be collected even if the diameter of the chip body 21 is small. The puncture needle 13 preferably has a diameter of 1000 μm or less.

  Furthermore, a substantially cylindrical elastic body 15 is provided at the distal end of the biosensor cartridge 11 so that the puncture needle 13 is inserted and the puncture needle 13 protrudes from the distal end surface during compression. A concave portion 19 is formed on the distal end surface of the elastic body 15, and the concave portion 19 has a hemispherical bulging portion 18 formed at the center bottom. A through hole 16 that penetrates the elastic body 15 is formed in the center of the bulging portion 18, and the through hole 16 is formed larger than the outer diameter of the puncture needle 13 so that the puncture needle 13 of the chip body 21 is inserted. . The dimension of the elastic body 15 in the axial direction is a length that can reliably cover the tip of the puncture needle 13. That is, the puncture needle 13 is arranged inside the bulging portion 18.

  The elastic body 15 is deformed so that the peripheral wall portion 17 of the distal end surface is crushed by the compressive force in the axial direction. Further, when the same compressive force is applied, the bulging portion 18 is also deformed so as to be crushed to the vicinity of the bottom surface of the concave portion 19. That is, the puncture needle 13 is relatively projected from the distal end surface of the elastic body 15 by the action of the compressive force. This compressive force is applied by the compression coil spring 37 of the drive mechanism 31.

  The material of the elastic body 15 is not particularly limited as long as it has elasticity. However, the elastic body 15 is made of a single polymer or a copolymerized polymer such as silicone, urethane, acrylic, ethylene, styrene, butadiene, acrylonitrile, propylene, and chloroprene. Rubber or sponge, polyethylene, polyolefin such as polypropylene, polyester such as polyethylene terephthalate and polybutylene terephthalate, polytetrafluoroethylene and fluororesin such as PFA which is a copolymer of perfluoroalkoxyethylene and polyfluoroethylene, etc. can be used .

  As shown in FIG. 1, the measurement device 30 is provided with a switch 33 for activating a drive mechanism 31 that drives the connector 32 to puncture the measurement device main body 40. In addition, a power supply 34, a control device 35, and a display unit 36 are provided inside the measuring device 30, and these are electrically connected to each other.

At the front end of the connector 32, the rear end portion 21b of the chip body 21 is inserted and fixed, and a terminal insertion portion 32a that is electrically connected to the detection electrodes 24a and 24b is provided, and the biosensor chip 20 is attached. In this state, it is driven forward (downward in FIG. 1), which is the puncturing direction.
Examples of the drive mechanism 31 include the compression coil spring 37 in the illustrated example, or an actuator such as a solenoid or a motor.

  The connector 32 disposed so as to be movable in the puncture direction with respect to the measuring device main body 40 is electrically connected to the control device 35 of the measuring device 30 through the movable electrodes 39 and 39 and the fixed electrodes 41 and 41. The reaction between the sample and the reagent 26 detected by the detection electrodes 24 a and 24 b of the biosensor chip 20 is transmitted to the control device 35.

  The movable electrodes 39, 39 are electrically connected to the terminal insertion portion 32a by electric wires or printed wiring 43, and are formed as, for example, hemispherical protrusions made of a conductive metal material such as copper. In addition, as the moving electrode 39, means such as a conductive brush, a leaf spring, and a roller can be used.

  The fixed electrode 41 is electrically connected to the measuring device 30 by an electric wire or a printed wiring 45, and extends along the moving direction of the moving electrode 39 on the inner wall surface of the space in which the driving mechanism 31 is accommodated. The fixed electrode 41 is formed as a foil, thin plate, rail, or the like made of a conductive metal material such as copper. In the present embodiment, the fixed electrode 41 is formed along the movement locus of the moving electrode 39. That is, the movable electrode 39 and the fixed electrode 41 can always maintain a conductive state.

Next, the operation of the needle-integrated measuring apparatus 10 configured as described above will be described.
FIG. 3A is a schematic cross-sectional view of a main part showing a state during puncturing of the needle integrated measuring apparatus according to the first embodiment, and FIG. 3B is a diagram after puncturing of the needle integrated measuring apparatus according to the first embodiment. It is a principal part schematic sectional drawing which shows this state.

This needle-integrated measuring apparatus 10 is small in size, for example, is a handy type that can be held by a user with one hand, and can be operated by the user himself.
First, the biosensor chip 20 is inserted and attached to the terminal insertion portion 32a of the connector 32 in the needle integrated measuring apparatus 10. When the biosensor chip 20 is attached to the terminal insertion portion 32 a of the connector 32, the biosensor chip 20 is electrically connected to the moving electrode 39 of the connector 32.

  Then, the compression coil spring 37 of the drive mechanism 31 is compressed by a cocking lever or the like (not shown) and held in the urging force accumulation state. In this state, the connector 32 to which the biosensor chip 20 is attached is moved to the position shown in FIG. At this time, when the moving electrode 39 comes into contact with the fixed electrode 41, the measuring device 30 can detect the biosensor cartridge 11 attached to the connector 32. That is, the needle-integrated measuring apparatus 10 according to the present embodiment can check the operation of the biosensor chip 11 and the mounting state.

Then, as shown in FIG. 1, for example, a fingertip that is the subject M is pressed so as to close the measurement opening 47 of the needle-integrated measurement apparatus 10.
When the switch 33 is pressed in this state, the drive mechanism 31 punctures the connector 32 with respect to the measurement apparatus main body 40, so that the tip of the biosensor cartridge 11 protrudes from the measurement opening 47. When the biosensor cartridge 11 is pressed against the subject M with a predetermined pressing force, the peripheral wall portion 17 and the bulging portion 18 of the elastic body 15 are crushed and the puncture needle 13 is projected as shown in FIG. The

  Thereby, the tip of the protruding puncture needle 13 is punctured into the subject M. As shown in FIG. 3B, the elastic body 15 deformed by the pressing force returns to its original shape by the restoring force. At the same time, the compression coil spring 37 also returns to the natural length state, the biosensor cartridge 11 is slightly retracted, and reaches the final movement measurement position where the puncture needle 13 is removed from the subject M and stops.

When the puncture needle 13 is removed from the subject M, the blood B flowing out from the puncture hole is guided to the sample collection port 25a opened at the tip of the biosensor chip 20, and the sample collection port 25a leads to the hollow reaction unit 25. Inflow.
At this time, simultaneously with the depression of the switch 33, a negative pressure is applied from the vacuum suction means (not shown) into the measuring apparatus main body 40, and the negative pressure is applied to the blood B flowing out from the puncture hole via the measurement opening 47. The blood B may be efficiently sucked into the hollow reaction part 25 of the biosensor chip 20.

  Then, when the blood B flowing into the hollow reaction part 25 reacts with the reagent 26, a current is generated, and this current flows to the detection electrodes 24a, 24b of the substrate 22a, causing the moving electrodes 39, 39 and the fixed electrodes 41, 41 to flow. Via the printed wiring 45 to the measuring device 30. Thereby, components in the blood are measured, and the measurement result is displayed on the display unit 36 by the control device 35.

  As described above, the movable electrode 39 of the connector 32 to which the biosensor chip 20 is attached is movable while contacting the fixed electrode 41 and maintaining the conductive state, so that the biosensor chip 20 is electrically connected to the measuring device 30. Will be connected to. The fixed electrode 41 is formed along the movement locus of the moving electrode 39, that is, the moving range, and the moving electrode 39 maintains a contact state with the fixed electrode 41 at an arbitrary moving position. Therefore, the movable electrodes 39, 39 and the fixed electrodes 41, 41 do not intermittently contact each other, and are always in stable contact, and the electrical connection reliability is increased.

  Therefore, according to the needle integrated measurement device 10 of the present embodiment, the movable electrode 39 provided in the connector 32 of the drive mechanism 31 and electrically connected to the biosensor chip 20 and the measurement device main body 40 are provided, and at least Since the fixed electrode 41 that contacts the moving electrode 39 and electrically connects the biosensor chip 20 and the measuring device 30 after the puncture of the puncture needle 13 is provided, the puncture needle 13 and the biosensor chip 20 are driven to puncture simultaneously. Thus, even when puncturing and sampling are performed, electrical connection between the biosensor chip 20 and the measuring device 30 can be achieved with a simple structure.

  Furthermore, it is possible to prevent an increase in driving resistance due to an electric wire having a connection structure using a general vinyl-coated electric wire that is too hard, thereby enabling a smooth puncturing operation. Further, it is possible to prevent an increase in electric resistance when a thin electric wire is used to reduce the driving resistance. Further, disconnection due to deformation fatigue that occurs in the connection structure using electric wires can be prevented. Moreover, failure of the measuring device 30 and measurement failure due to the electric wire being caught in the drive mechanism 31 can be prevented.

  Therefore, the needle-integrated measurement apparatus 10 of the present embodiment collects the puncture and sample collection by driving the biosensor cartridge 11 integrally provided with the puncture needle 13 and the biosensor chip 20 by the drive mechanism 31. Information on the sample can be reliably transmitted from the biosensor chip 20 to the measuring device 30, and measurement can be performed in a short time and easily, thereby reducing the burden on the user.

Next, a needle integrated measuring apparatus according to a second embodiment of the present invention will be described.
4A and 4B are schematic cross-sectional views of a main part of the needle-integrated measuring apparatus according to the second embodiment of the present invention, where FIG. 4A shows a state during puncturing, and FIG. 4B shows a state after puncturing. In addition, the same code | symbol is attached | subjected to the member same as the needle | hook integrated measuring apparatus 10 of the said 1st Embodiment, and the overlapping description shall be abbreviate | omitted.

As shown in FIG. 3, the needle-integrated measuring apparatus 50 according to the second embodiment is arranged such that the fixed electrodes 41 </ b> A and 41 </ b> A are in contact with the moving electrodes 39 and 39 after puncturing the puncture needle 13. Yes.
Furthermore, these fixed electrodes 41A and 41A are formed of elastic contact terminals that can be elastically displaced in the contact direction by a pressing force received by the movement electrodes 39 and 39 being over the same. That is, the fixed electrodes 41A and 41A are integrally formed with a base 53 fixed to the inner wall of the measuring device main body 40 and a cantilevered tip contact portion 55 that is a curved free end. For example, beryllium copper, stainless steel, phosphor bronze, or conductive rubber can be used as the elastic contact terminal.

  In the needle-integrated measurement device 50 according to the second embodiment, as shown in FIG. 4A, when the drive mechanism 31 punctures the connector 32 with respect to the measurement device main body 40, the peripheral wall portion 17 of the elastic body 15. Since the bulging portion 18 is crushed and the puncture needle 13 is projected, the tip of the projected puncture needle 13 is punctured into the subject M. As shown in FIG. 4B, the elastic body 15 deformed by the pressing force returns to its original shape by the restoring force. At the same time, the compression coil spring 37 also returns to the natural length state, the biosensor cartridge 11 is slightly retracted, and reaches the final movement measurement position where the puncture needle 13 is removed from the subject M and stops.

  At this time, each moving electrode 39 comes into contact with the tip contact portion 55 of the fixed electrode 41A. That is, each moving electrode 39 comes into contact with the fixed electrode 41A with the start of puncturing, and maintains the contact state with the fixed electrode 41A at the final moving measurement position where the puncture needle 13 is removed and measurement is started.

  At this time, the movable electrode 39 and the fixed electrode 41A that are in elastic contact are in stable contact, and electrical connection reliability is increased. Further, when the moving electrode 39 gets over the tip contact portion 55 of the fixed electrode 41A, the fixed electrode 41A is elastically deformed to reduce the reaction force received by the moving electrode 39, so that the moving resistance when the moving electrode 39 gets over is reduced. Can be small.

  According to the needle-integrated measuring apparatus 50 according to the second embodiment, the moving electrode 39 and the fixed electrode 41A are in contact only after necessary puncture, and wear due to sliding of the moving electrode 39 and the fixed electrode 41A is reduced. be able to. In addition, the manufacturing area can be reduced by reducing the formation area of the fixed electrode 41A.

  The configuration of the puncture device, biosensor chip, biosensor cartridge, connector, measurement device main body, drive mechanism, moving electrode, fixed electrode, and the like related to the needle integrated measurement device of the present invention is limited to the configuration of the above-described embodiment. Needless to say, appropriate modifications and improvements can be made based on the gist of the present invention.

It is a lineblock diagram of the needle integrated measuring device concerning a 1st embodiment of the present invention. (A) is sectional drawing which shows an example of a biosensor chip. FIG. 2B is an end view of the biosensor chip viewed from the direction A in FIG. (A) is a principal part schematic sectional drawing which shows the state during the puncture of the needle integrated measuring device which concerns on 1st Embodiment, (b) shows the state after the puncture of the needle integrated measuring device which concerns on 1st Embodiment. It is a principal part schematic sectional drawing. (A) is a principal part schematic sectional drawing which shows the state during the puncture of the needle integrated measuring device which concerns on 2nd Embodiment of this invention, (b) is after the puncture of the needle integrated measuring device which concerns on 2nd Embodiment. It is a principal part schematic sectional drawing which shows a state. (A) is a perspective view showing a conventional biosensor chip, (B) is an exploded perspective view showing a conventional biosensor chip.

Explanation of symbols

DESCRIPTION OF SYMBOLS 10,50 ... Needle integrated measuring device 11 ... Biosensor cartridge 13 ... Puncture needle 15 ... Elastic body 20 ... Biosensor chip 30 ... Measuring device 31 ... Drive mechanism 32 ... Connector 39 ... Moving electrode 40 ... Measuring device main body 41, 41A ... Fixed electrode

Claims (5)

A connector to which a biosensor cartridge integrally including a puncture device and a biosensor chip is detachably mounted;
A drive mechanism for driving the connector to puncture the measurement apparatus body;
A moving electrode provided in the connector and electrically conducting with the biosensor chip of the biosensor cartridge when the cartridge is mounted;
A fixed electrode that is provided in the measuring device main body and at least contacts the moving electrode after puncturing the puncture device to electrically connect the biosensor chip and the measuring device;
A needle-integrated measuring apparatus comprising:   The needle-integrated measuring apparatus according to claim 1, wherein the fixed electrode extends along a movement locus of the moving electrode.   The needle-integrated measuring apparatus according to claim 1, wherein the fixed electrode is disposed at a position that comes into contact with the moving electrode at least after puncturing the puncture device.   The needle-integrated measuring apparatus according to claim 3, wherein the fixed electrode is disposed at a position in contact with the moving electrode before and after puncturing the puncture device.   5. The needle-integrated measurement apparatus according to claim 1, wherein at least one of the moving electrode and the fixed electrode includes an elastic contact terminal that can be elastically displaced in a contact direction.

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