JP2008074727A - Composition for removing active oxygen radical, and active oxygen radical remover for hair containing the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a composition for removing an active oxygen radical which contains an active oxygen radical scavenger having active oxygen radical-scavenging activities, and a material (α-material) for extremely improving the active oxygen radical-scavenging activities of the scavenger; and to provide an active oxygen radical remover for the hair, a pretreatment agent/intermediate treatment agent/posttreatment agent for hair dyeing and a pretreatment agent/intermediate treatment agent/posttreatment agent for permanent waving. <P>SOLUTION: The composition for removing the active oxygen radical comprises at least one kind of the active oxygen radical scavenger selected from γ-keratose, eucalyptus essence and rosemary essence, and the specific α-material, and is suitably usable as the pretreatment agent/intermediate treatment agent/posttreatment agent for the hair dyeing and the pretreatment agent/intermediate treatment agent/posttreatment agent for the permanent waving. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a composition for removing active oxygen radicals and a hair active oxygen radical removing agent containing the same. More specifically, the present invention relates to an active oxygen radical scavenger having active oxygen radical scavenging ability, and a composition for removing active oxygen radicals, a hair activity comprising a substance that dramatically improves the active oxygen radical scavenging ability of the scavenger. The present invention relates to oxygen radical scavengers, hair dyeing pre-treatment agents, intermediate treatment agents, post-treatment agents, permanent wave pre-treatment agents, intermediate treatment agents, and post-treatment agents.

  In recent years, with regard to research on active oxygen radicals (hereinafter also referred to as active oxygen), in the X (active oxygen species) Y (catalyst species) Z (accepting species) system, electron transfer occurs between these XYZs, resulting in an excited state At the same time, the phenomenon causing weak light emission and its mechanism were clarified. Means for measuring the ability to remove active oxygen using this weak luminescence mechanism have been reported, and compositions that have been evaluated to have an ability to remove active oxygen by such means, for example, an active oxygen radical scavenger, uronic acids, A composition for removing active oxygen radicals containing uronides, mucopolysaccharides, amino acids / peptides, and the like has been reported (see Non-Patent Document 1 and Patent Document 1).

  Furthermore, as an improved version of the evaluation of active oxygen removal ability using the XYZ-based weak light emission mechanism, hydrogen peroxide as X (active oxygen species), active oxygen removal substance candidate as Y (active oxygen removal substance), Z (mediator) ) Using an alkali metal hydrogen carbonate salt, the presence or absence of weak light emission is detected, and if weak light emission is detected, a method of determining that the candidate substance used as Y is a substance capable of removing active oxygen is It has been proposed (see Patent Document 2).

Active oxygen generally means superoxide (.O ₂ ⁻ ), hydrogen peroxide (H ₂ O ₂ ), hydroxy radical (HO.), Singlet oxygen ( ¹ O ₂ ), Peroxy radicals (HOO.), Peroxy radicals (LOO.), Alkoxy radicals (LO.) And the like are also included.

  Such active oxygen is thought to damage cells and DNA and contribute to various diseases. Regarding hair (especially hair), active oxygen generated by oxygen activation by strong ultraviolet rays, etc., or active oxygen generated by two-part oxidative hair dyes and permanent wave treatment agents that use hydrogen peroxide However, it damages the hair, and the accumulation of this damage causes serious hair damage, and the degradation of the dye polymer is accelerated in the hair that has been dyed, resulting in discoloration and fading of the hair after dyeing. It is known to advance.

However, since the known active oxygen radical removing composition is not necessarily suitable for preventing damage, discoloration, and fading of such hair, it has excellent active oxygen radical removal ability and damage to hair. Development of a composition for removing active oxygen radicals suitable for preventing discoloration and fading has been desired.
Japanese Patent Laid-Open No. 9-241437 JP 2002-148194 A Yoshiki Yumiko, Okubo Kazuyoshi, Chemistry and Biology, vol. 35, no. 12, 1997, pages 839-845

  The present invention includes an active oxygen radical scavenger having an ability to remove active oxygen radicals, and a composition for removing active oxygen radicals, which includes a substance (hereinafter also referred to as α substance) that dramatically improves the active oxygen radical removing ability of the scavenger. Active oxygen radical scavenger for hair, hair dyeing pretreatment agent / intermediate treatment agent / posttreatment agent, permanent wave pretreatment agent / intermediate treatment agent / posttreatment The issue is to provide a drug.

  As a result of intensive studies to solve the above-mentioned problems, the present inventors have added a specific substance as an α substance to at least one active oxygen radical scavenger selected from the group consisting of γ-keratose, eucalyptus extract, and rosemary extract. When combined, the inventors have found that a composition for removing active oxygen radicals that is excellent in ability to remove active oxygen radicals and that is suitable for preventing damage, discoloration, and fading of hair can be obtained, and the present invention has been completed.

That is, the present invention relates to the following matters.
The first active oxygen radical scavenging composition according to the present invention comprises at least one active oxygen radical scavenger selected from the group consisting of γ-keratose, eucalyptus extract, and rosemary extract, and a reducing sugar. It is characterized by.

  The second active oxygen radical scavenging composition according to the present invention is a structural unit derived from at least one active oxygen radical scavenger selected from the group consisting of γ-keratose, eucalyptus extract, and rosemary extract, and at least fucose. It is characterized by comprising the polysaccharide which has.

A third active oxygen radical scavenging composition according to the present invention is a yeast obtained from at least one active oxygen radical scavenger selected from the group consisting of γ-keratose, eucalyptus extract and rosemary extract, and yeast (Saccharomyces). It is characterized by comprising an extract.

  In the present invention, the γ-keratose preferably has an average molecular weight of 20,000 to 40,000. The reducing sugar is preferably at least one selected from the group consisting of glucose, fructose, fucose, mannose, xylose and galactose. The polysaccharide is preferably derived from a seaweed extract, and is preferably fucoidan.

The active oxygen radical removing composition according to the present invention is suitably used as a hair active oxygen radical removing agent.
The hair dyeing pretreatment agent according to the present invention contains the composition for removing active oxygen radicals, and is attached to the hair before the treatment before the hair dyeing treatment using the oxidative hair dye. It is characterized by that.

  The hair dye intermediate treatment agent according to the present invention contains the composition for removing active oxygen radicals, and is attached to the hair after hair is dyed and washed with water using an oxidative hair dye. It is characterized by.

  The hair dyeing post-treatment agent according to the present invention contains the composition for removing active oxygen radicals, and after hair is dyed using an oxidative hair dye, it is washed with water, and further a surfactant and water. It is characterized in that it is attached to the hair after washing with.

The permanent wave pretreatment agent according to the present invention comprises the active oxygen radical removing composition, and is attached to the hair before treatment before the permanent wave treatment of the hair using the permanent wave agent. It is characterized by.

  The permanent wave intermediate treatment agent according to the present invention contains the composition for removing active oxygen radicals, and the permanent wave agent is used to permanently wave the hair using the permanent wave agent, and is attached to the hair after being washed with water. It is a feature.

  The permanent wave post-treatment agent according to the present invention contains the composition for removing active oxygen radicals, and after permanent hair treatment of the hair using the permanent wave agent, the hair is washed with water, and further with a surfactant and water. It is characterized by being attached to the hair after washing.

  The composition for removing active oxygen radicals of the present invention contains components suitable for hair and has dramatically improved ability to remove active oxygen radicals. By using it as an intermediate treatment / post-treatment agent, permanent wave pre-treatment agent / intermediate treatment agent / post-treatment agent, the active oxygen present on or inside the hair is removed and the hair is damaged due to the presence of active oxygen. , Discoloration and fading can be effectively prevented.

Hereinafter, the present invention will be specifically described.
<Composition for removing active oxygen radicals>
The active oxygen radical scavenging composition of the present invention contains at least one active oxygen radical scavenger selected from the group consisting of γ-keratose, eucalyptus extract, and rosemary extract, and a specific α substance. It may further contain other components.

((Active oxygen radical scavenger))
Preferred examples of the active oxygen radical scavenger that can be used in the present invention include γ-keratose, eucalyptus extract, and rosemary extract. These alone exhibit active oxygen radical scavenger action, but when combined with an α component described later, the active oxygen radical scavenger effect is dramatically improved. Moreover, as will be described later, γ-keratose is a hydrolyzate of keratin, which is the main component of hair, and eucalyptus extract and rosemary extract are herbal extracts having a moisturizing effect, and thus damage the hair. There is very little fear and it is suitable for removing active oxygen present on or inside the hair without damaging the hair.

Each component will be described in detail below.
γ-keratose γ-keratose is a kind of hydrolyzed keratin. Keratin is a fibrous protein composed of 20 kinds of amino acids constituting the skin and hair, and hydrolyzed keratin is hydrolyzed keratin.

  The molecular weight of hydrolyzed keratin can be adjusted as appropriate depending on the degree of hydrolysis. Hydrolyzed keratin has a relatively low molecular weight oligopeptide with an average molecular weight of several tens of thousands to a high molecular weight protein with an average molecular weight of several tens of thousands. Is included.

  Furthermore, the hydrolyzed keratin includes α-keratose derived from crystalline keratin, γ-keratose derived from amorphous keratin, or a modified product thereof. Among these, radical scavengers used in the present invention include From the viewpoints of stability in the presence of an aqueous medium and good handling in the preparation, γ-keratose is preferable.

The average molecular weight of γ-keratose used in the present invention is usually in the range of 20,000 to 40,000.
In the present specification, the average molecular weight is determined based on a calibration curve prepared from the relationship between the molecular weight and the elution time by measuring the elution time by high performance liquid chromatography using a plurality of molecular weight standards having known molecular weights. be able to.

  As this (gamma) -keratose, a well-known thing can be used suitably. For example, “Hydrolyzed keratin powder” and “Hydrolyzed keratin liquid” published in JP-A-10-77209, which are described in cosmetic ingredient-specific combination ingredient standards (supervised by the Pharmaceutical Affairs Bureau, Ministry of Health and Welfare, published by Yakuji Nippo, 1997) Keratin hydrolysis products, commercially available products (for example, “Proticute H-gamma” manufactured by Ichimaru Falcos Co., Ltd.) and the like may be used as they are as a composition containing γ-keratose. Keratose may be isolated and used by a known means.

  When such a composition containing γ-keratose is used as it is, when the γ-keratose content in the composition is clear, the blending amount described later is determined based on the content. Sometimes the γ-keratose content is not clear. In that case, it is convenient only when it is clear that the composition contains γ-keratose as a main component (for example, when the γ-keratose content in the composition exceeds 50% by weight). The amount of the composition may be regarded as the amount of γ-keratose and the blending amount described later may be determined.

Eucalyptus extract, rosemary extract Eucalyptus extract and rosemary extract are eucalyptus (Eucalyptus globulus, Eucalyptus citriodora) and rosemary (Rosmarinus officinalis L.), respectively.
Since it is an extract extracted by steam distillation or in an aqueous or oily medium and is a natural plant extract, the detailed composition of the ingredients is not clear.

  The eucalyptus extract and rosemary extract may be obtained by extraction from the above-mentioned plants by known means, or commercially available ones may be used. When using a commercially available product as it is, the concentrations of the eucalyptus extract and rosemary extract contained in the commercially available product are not particularly limited, but when blended in the active oxygen radical removing composition of the present invention, Based on the amounts contained in the product as eucalyptus extract stock solution and rosemary extract stock solution, the blending amount described later can be determined.

In addition, these active oxygen radical scavengers may be used individually by 1 type, and may be used in combination of 2 or more type, unless the objective of this invention is impaired.
The active oxygen radical scavenger is usually added in an amount of 0.01 to 20% by weight, preferably 0.05 to 10% by weight, in the total amount of the active oxygen radical removing composition of the present invention. When the active oxygen radical scavenger is added to the active oxygen radical removing composition in an amount within the above range, the active oxygen radical removing ability as much as it has can be exhibited without damaging the hair.

((Α substance))
The α substance that can be used in the present invention, that is, the substance that can dramatically improve the active oxygen radical scavenging ability of the active oxygen radical scavenger includes a reducing sugar, a polysaccharide having at least a structural unit derived from fucose, Examples include yeast extract. In addition, while the α substance can dramatically improve the active oxygen radical scavenging ability of the active oxygen radical scavenger, it itself has little or no ability to remove active oxygen by itself. There is a feature.

Reducing sugar Examples of the reducing sugar used in the present invention include monosaccharides, disaccharides, and trisaccharides having an aldehyde group. Specifically, for example, monosaccharides such as glucose, fructose, fucose, mannose, xylose, galactose, talose, erythrose, threose, ribose, arabinose, allose, idose, lyxose, disaccharides such as maltose, cellobiose, lactose, xylo Trisaccharides such as triose and maltotriose can be mentioned. The reducing sugar may be D-form or L-form, but means D-form unless otherwise specified. In the present specification, reducing sugar does not mean uronic acid or uronides.

  Of these, glucose, fructose, fucose, mannose, xylose, and galactose are preferable from the viewpoint of improving the active oxygen radical scavenger's ability to improve the active oxygen radical scavenger and ease of handling when formulating.

Polysaccharides having at least a constituent unit derived from fucose The polysaccharides having at least a constituent unit derived from fucose used in the present invention include those derived from a seaweed extract in addition to a synthetic product. In addition, it cannot be overemphasized that this polysaccharide does not contain the reducing sugar mentioned above. Among these polysaccharides, those derived from seaweed extract are preferred because of their availability.

The seaweed extract is generally divided into brown algae (Phaeophyta) (comb, wakame, hibamata, etc.), red algae (Rhodeophyta, etc.), green algae (Chlorophayta) (Aonori,
This is a seaweed extract such as Aosa, Chlorella, etc., and is generally known as a seaweed extract obtained by extracting various seaweeds in an aqueous medium (water, butylene glycol, etc.), and various components depending on the type of seaweed It is included. As characteristic polysaccharides contained in each seaweed, for example, it is known that brown algae contains alginic acid and fucoidan, red algae contains carrageenan and agarose, and green algae contains starch. In addition to these, it is known that the seaweed extract contains amino acids, minerals, mannitol, carbohydrates, etc., but details of all components are not clear.

  Among these, as the polysaccharide having at least a structural unit derived from fucose used in the present invention, those derived from brown algae extract are preferably mentioned, and fucoidan is more preferred.

  Fucoidan is a general term for polysaccharides in which fucose, xylose, galactose, mannose, uronic acid, sulfuric acid and the like are polymerized. In addition to F-fucoidan that does not contain a structural unit derived from xylose, G-fucoidan, U-fucoidan, etc. It has been known. The fucoidan used in the present invention may be any of these or a mixture thereof.

In the present invention, fucoidan may be isolated from a brown algae extract by a known method and a seaweed extract containing the brown algae extract may be used as it is.
Commercially available seaweed extracts include, for example, seaweed extracts (1) to (4), Ichimaru Falcos, which are listed in cosmetic ingredient-specific combination ingredient specifications (supervised by the Pharmaceutical Affairs Bureau, Ministry of Health and Welfare, published by Yakuji Nipposha, 1997). "Falco Rex Hibamata ^TM ", "Alger Rex ^TM ", "Marine Purge ^TM ", "Sea Breast White ^TM ", "Sea Breast Gold ^TM ", etc., are available. It is also possible to use seaweed powder (1) dissolved in a suitable solvent, which is described in the formulation standard for cosmetic varieties (supervised by the Pharmaceutical Affairs Bureau, Ministry of Health and Welfare, published by Yakuji Nippo, 1997). As long as the brown algae extract (brown algae extract) is contained, the seaweed extract may contain other red algae extracts and green algae extracts. In particular, when the red algae extract is contained together with the brown algae extract, α It is expected that the effect as a substance, that is, the effect of improving the ability to remove active oxygen radicals by the active oxygen radical scavenger will be further enhanced.

  When the seaweed extract is used as it is, the content of the polysaccharide having a structural unit derived from at least fucose in the seaweed extract may not be clear, but in that case, it is commercially available for convenience. Assuming that the amount of the brown algae extract stock solution contained in the seaweed extract is the amount of the polysaccharide, the blending amount described later can be determined.

Yeast extract Yeast extract is a liquid obtained by self-digestion or acid hydrolysis of yeast belonging to Saccaromayces, or a liquid obtained by drying yeast powder to obtain powder as needed. Filtered or concentrated or dried liquid or powder containing various amino acids, glutathione, vitamins, nucleic acid related substances, inorganic salts, organic acids, proteins, carbohydrates, lipids, etc. Also called “hydrolyzed yeast extract”.

  Glutathione is a tripeptide composed of three amino acids, glutamic acid, cysteine, and glycine, and is known to have an antioxidative action, so it can be classified as an active oxygen radical scavenger. Since yeast extract is a composition containing various components in addition to glutathione, in this specification, the whole yeast extract is classified as an α substance that dramatically improves the scavenger's ability to remove active oxygen radicals. To do.

As the yeast extract, those known as “yeast extract” or “hydrolyzed yeast extract” can be used as appropriate. For example, the composition standard for each cosmetic variety (supervised by the Ministry of Health and Welfare Pharmaceutical Affairs Bureau, Pharmacy Daily, 1997) yeast extract (1) to (5), commercially available products such as “East Liquid GB ^™ ” and “East Liquid B ^™ ” manufactured by Ichimaru Falcos Co., Ltd. can be used.

  In addition, when using a commercially available product as it is, the concentration of the yeast extract contained in the commercially available product is not particularly limited, but when blended in the active oxygen radical removing composition of the present invention, yeast contained in the commercially available product. Based on the amount contained as the extract stock solution (or hydrolyzed yeast extract stock solution), the blending amount described later can be determined.

((Other))
The composition for removing active oxygen radicals of the present invention may further contain known components used for cosmetics, if necessary, according to the application and dosage form.

  For example, water is preferably used as the medium because the above-described components can be easily dissolved or dispersed, and the viscosity and concentration of the entire composition can be easily adjusted. Although it does not specifically limit as water which can be used for this invention, Purified water, such as ion-exchange water and distilled water, is mentioned preferably.

Further, for example, a cationic surfactant, an anionic surfactant, a nonionic surfactant, and an amphoteric surfactant can be used as necessary.
Specifically, for example, as a cationic surfactant, alkyltrimethylammonium chloride, lauryltrimethylammonium chloride, cetyltrimethylammonium chloride, stearyltrimethylammonium chloride (stearyltrimonium chloride), behentrimonium chloride, distearyldimethylchloride Ammonium, dicocoyldimethylammonium chloride, tri (polyoxyethylene) stearylammonium chloride (5E.O.), di (polyoxyethylene) oleylmethylammonium chloride (2E.O.), lauryltrimethylammonium bromide, cetyl bromide Quaternary ammonium salts such as trimethylammonium and stearyltrimethylammonium bromides; fatty acid amidoamine salts; alkyltrialkylene glycol ammonium salts; Nium salt; benzethonium salt; pyridium salt; imidazolinium salt and the like.

  Examples of the anionic surfactant include alkyl sulfates such as sodium lauryl sulfate; POE alkyl / alkyl such as polyoxyethylene (hereinafter abbreviated as POE) sodium lauryl ether sulfate (Naureth laureth) and sodium POE nonylphenyl ether sulfate. Allyl ether sulfate; sodium cocoyl methyl taurate; sulfosuccinate; N-acyl sulfonate; alkyl benzene sulfonate; α-olefin sulfonate; alkane sulfonate; N-acyl amino acid salt; The salt etc. are mentioned.

Nonionic surfactants include POE alkyl ethers; POE polyoxypropylene alkyl ethers; polyhydric alcohol fatty acid esters; glycerin fatty acid esters; polyglycerin fatty acid esters; sorbitan fatty acid esters such as sorbitan sesquioleate POE glycerin fatty acid esters; POE sorbitan fatty acid esters such as polyoxyethylene sorbitan monostearate (20E.O.); POE sorbite fatty acid esters; polyethylene glycol fatty acid esters; alkyl alkanolamides; cocamide diethanolamide ( Fatty acid alkanolamides such as cocamide DEA); POE hydrogenated castor oil; pyroglutamic acid isostearic acid POE hydrogenated castor oil; POE ethylene lanolin; Roll; POE phytosterol; POE cholestanol; and POE phytostanols can be mentioned.

  Examples of amphoteric surfactants include betaine types such as cocamidopropyl betaine and lauryldimethylaminoacetic acid betaine; imidazoline types such as 2-undecyl-N, N, N- (hydroxyethylcarboxymethyl) -2-imidazoline sodium; Examples include amino acid type.

  Further, for example, pH adjusters such as citric acid, sodium citrate, triethanolamine; hair protecting agents such as keratin, hydrolyzed keratin other than γ-keratose, silylated polypeptide, amino acid, pyrrolidone carboxylic acid derivative, and pseudoceramide Oils and fats such as shea butter; higher alcohols such as cetostearyl alcohol and behenyl alcohol; moisturizers such as polyquaternium; wetting agents such as glycerin, propylene glycol, and 1,3-butylene glycol; ascorbic acid, erythorbic acid, edetate, and etidone Stabilizers such as acid salts, phenacetin, and salicylic acid; preservatives such as methylparaben, butylparaben, propylparaben, phenoxyethanol, and sodium benzoate; hair nourishing agents; ultraviolet absorbers; fragrances; dyes; It is.

((Mixing ratio))
In the present invention, each α substance is blended in the active oxygen radical removing composition so as to be contained in the following ratio according to the type of the active oxygen radical scavenger.

For example, when the active oxygen radical scavenger is γ-keratose, with respect to 1 part by weight of γ-keratose,
The reducing sugar is usually 0.1 to 30 parts by weight, preferably 0.5 to 20 parts by weight, more preferably 1 to 10 parts by weight,
The polysaccharide having a structural unit derived from at least fucose is in the range of 1 × 10 ⁻⁵ to 2 parts by weight, and fucoidan is usually 1 × 10 ⁻³ to 2 parts by weight, preferably 5 × 10 ^{− 3 to} 0.5 parts by weight, more preferably 0.01 to 0.1 parts by weight,
Moreover, yeast extract is normally mix | blended with the composition for active oxygen radical removal so that it may be contained in the quantity of 1 * 10 < ^-3 > ^-1 weight part.

For example, when the active oxygen radical scavenger is a eucalyptus extract or a rosemary extract,
The reducing sugar is usually 0.01 to 300 parts by weight, preferably 0.1 to 200 parts by weight, more preferably 1 to 150 parts by weight.
Further, the polysaccharide having at least a structural unit derived from fucose is in the range of 1 × 10 ⁻³ to 10 parts by weight, and fucoidan is usually 0.01 to 10 parts by weight, preferably 0.1 to 8 parts by weight. Parts, more preferably in an amount of 0.5 to 5 parts by weight,
A yeast extract is normally mix | blended with the composition for active oxygen radical removal so that it may be contained in the quantity of 1 * 10 < ^-3 > -5 weight part.

  In the composition for removing active oxygen radicals of the present invention, when each α substance is included in the above-mentioned range according to the type of the active oxygen radical scavenger, the active oxygen radical scavenger has the ability to remove active oxygen radicals. As a result, it is possible to remove not only the hair surface but also active oxygen radicals present inside, and effects such as prevention of hair damage, discoloration, and fading are also achieved. On the other hand, even if the α substance is added to the composition beyond the above range, the effect of improving the ability to remove active oxygen radicals has reached its peak, and on the contrary, the odor and null-sticking may occur and the feeling of use may deteriorate. .

Moreover, in this invention, the said other component is mix | blended with the composition for active oxygen radical removal as needed in the quantity in the range which does not impair the objective of this invention.
<Active oxygen radical scavenger for hair>
The composition for removing active oxygen radicals is suitably used as an active oxygen radical removing agent for hair, and is used by adhering to the hair surface in order to remove active oxygen inside or on the hair.

  Conventionally, shampoos and hair rinses containing keratin and seaweed extract have been put on the market for moisturizing hair and repairing damaged hair. However, no investigation has been made on the ability of the shampoo and hair rinse to remove active oxygen radicals, and since the amount of keratin is extremely small, it is difficult to exert sufficient ability to remove active oxygen radicals. it is conceivable that.

  On the other hand, the active oxygen radical scavenger for hair of the present invention has the composition already described as the active oxygen radical scavenging composition, and therefore, by the interaction with the α substance, the active oxygen radical scavenger active oxygen radical The removal ability is dramatically improved, and it becomes possible to remove not only the hair surface but also active oxygen radicals present inside, and effects such as prevention of hair damage, discoloration and fading are also achieved.

  The use of the active oxygen radical scavenger for hair of the present invention is not particularly limited as long as it is used for removing active oxygen on the hair surface or inside the hair, and the hair dyeing pretreatment agent, intermediate treatment agent, Hair treatment agents such as post-treatment agents, permanent wave pre-treatment agents, intermediate treatment agents, and post-treatment agents; hair washing agents such as shampoos and hair rinses (including treatment agents); scalp washing agents; hair styling agents, etc. . Hair means human hair and body hair as well as animal (mammal) body hair. Among them, the active oxygen radical scavenger for hair of the present invention is used for human hair. Is suitable.

Furthermore, the form of the active oxygen radical scavenger for hair of the present invention is not particularly limited, and may be a solution or a dispersed system. Further, the dosage form is not particularly limited, and any of liquid, spray, mist, emulsion, foam, gel, cream, wax and the like may be used.

  In the active oxygen radical scavenger for hair of the present invention, the above-mentioned components are appropriately stirred by a known method according to the use and dosage form of the agent, stirred, mixed, heated, cooled, dissolved, dispersed (emulsified) and the like. Can be manufactured.

  Further, depending on the use of the active oxygen radical scavenger for hair, the agent containing the active oxygen radical scavenger and the agent containing α substance are separately prepared in advance, and these agents are applied to the hair in any order. By applying, a method of mixing these on the hair and preparing a composition for removing active oxygen radicals can be adopted.

<Hair dyeing pretreatment agent / intermediate treatment agent / post treatment agent>
Among oxidative hair dyes, so-called two-component oxidative hair dyes are generally prepared by mixing a first agent containing an oxidative dye precursor or a coupler and a second agent containing hydrogen peroxide water. Used by applying to.

  Hydrogen peroxide contained in this hydrogen peroxide solution remains as active oxygen on the hair surface or inside the hair after dyeing, damaging the hair and promoting the decomposition of the dye polymer oxidized and polymerized inside the hair. Promote discoloration and fading of hair. In addition, if active oxygen is present on the surface or inside of the hair before hair dyeing, the function of the oxidative hair dye does not become uniform, making uniform hair dyeing difficult, or a dye polymer that is oxidatively polymerized inside the hair. Fixation of the hair is hindered, resulting in dullness in the color development after dyeing.

Hair dyeing pretreatment agent The hair dyeing pretreatment agent according to the present invention is a preferred embodiment of the active oxygen radical removing agent for hair described above, and contains the above-mentioned composition for removing active oxygen radicals, Unlike hair rinsing and the like, it is characterized in that it is attached to the hair before treatment before the hair is dyed using an oxidative hair dye.

  When the hair dyeing pretreatment agent is attached to the hair before the hair dyeing treatment, the active oxygen present in the hair can be removed and the original function of the oxidative hair dyeing agent can be achieved. More preferably, after the hair dyeing pretreatment agent is attached to the hair, the hair dyeing treatment may be performed as it is without being washed away.

  The means for attaching this hair dyeing pretreatment agent to the hair is not particularly limited, and the hair dyeing pretreatment agent is made into a mist form and sprayed on the hair, or applied with a brush or the like, or a container containing the hair dyeing pretreatment agent. Well-known means such as immersing hair in the hair.

The hair dyeing intermediate treatment agent The hair dyeing intermediate treatment agent according to the present invention is a preferred embodiment of the active oxygen radical removing agent for hair described above, and comprises the above-mentioned composition for removing active oxygen radicals, It is characterized in that the hair is dyed using an oxidative hair dye and then attached to the hair after washing with water.

  Active oxygen remains on the hair surface and inside the hair after the hair dyeing treatment, and it is difficult to remove it sufficiently with water. On the other hand, when the hair dye intermediate treatment agent is attached to the hair after washing with water, the active oxygen present in the hair is sufficiently removed, the decomposition of the dye polymer oxidized and polymerized in the hair is suppressed, and discoloration and Fading can be prevented. Moreover, hair pH can be adjusted and the damage of the hair by an oxidative hair dye can be reduced.

Furthermore, when γ-keratose is used as the active oxygen radical scavenger, after adhering to the hair surface, it can be expected to have a secondary effect that these penetrate into the hair and repair the hair damage. In addition, after attaching a hair dyeing intermediate treatment agent to hair and performing an active oxygen removal process, it is good to wash the hair using the washing | cleaning agent containing surfactant, such as shampoo.

The means for attaching this hair dyeing intermediate treatment agent to the hair is not particularly limited, and well-known means can be adopted in the same manner as the hair dyeing pretreatment agent.
Post-dye treatment agent The post-dye treatment agent according to the present invention is a preferred embodiment of the active oxygen radical scavenger for hair described above, and comprises the active oxygen radical scavenging composition, It is characterized in that it is hair-washed using an oxidative hair dye, then washed with water, and further attached to the hair after washing with a detergent containing a surfactant such as shampoo and water.

  Usually, the hair after the hair dyeing is washed with water and then washed with a detergent containing a surfactant such as shampoo, water, and if necessary, a hair rinse. Even after a washing treatment using a surfactant such as this shampoo or hair rinse, active oxygen may remain on the hair surface and inside.

  On the other hand, when the hair dyeing agent is attached to the hair after the washing treatment, the active oxygen present in the hair is sufficiently removed, and the oxidatively polymerized dye polymer is decomposed in the hair. Suppress and prevent discoloration and fading. Moreover, hair pH can be adjusted and the damage of the hair by an oxidative hair dye can be reduced.

  Furthermore, when γ-keratose is used as the active oxygen radical scavenger, after adhering to the hair surface, it can be expected to have a secondary effect that these penetrate into the hair and repair the hair damage.

  The means for attaching this hair dyeing post-treatment agent to the hair is not particularly limited, and known means can be adopted in the same manner as the hair dyeing pretreatment agent. After the hair dyeing treatment agent is attached to the hair and the active oxygen removal treatment is performed, the hair may be washed with a detergent containing a surfactant such as water or shampoo, or washed off as it is. You may dry without.

  In addition, since the hair dyeing pretreatment agent, the hair dyeing intermediate treatment agent, and the hair dyeing posttreatment agent each have an active oxygen radical removing ability, there are sufficient effects even if they are used alone. By using together, the effect can be further strengthened.

<Permanent wave pre-treatment agent / intermediate treatment agent / post-treatment agent>
Permanent wave agents may also use hydrogen peroxide. For example, in a two-bath type permanent wave agent, hydrogen peroxide is used as an oxidizing agent for re-forming the —S—S— bond.

  In this case, the hydrogen peroxide in the hydrogen peroxide water remains as active oxygen on the surface or inside of the hair after permanent wave treatment, and damages the hair. As a result, the shape of the wave is disturbed, and the permanent wave has poor durability. Become. In addition, if active oxygen is present on the surface or inside of the hair before the permanent wave treatment, the function of the reducing agent of the permanent wave agent is not uniform, making it difficult to form a uniform wave, and further making the wave itself difficult. It becomes.

Permanent wave pretreatment agent The permanent wave pretreatment agent according to the present invention is a preferred embodiment of the above-mentioned active oxygen radical removing agent for hair, and contains the above-mentioned composition for removing active oxygen radicals. Unlike hair rinsing and the like, it is characterized in that the permanent wave agent is used to attach the hair to the untreated hair before the permanent wave treatment.

  When the permanent wave pretreatment agent is attached to the hair before the permanent wave treatment, the active oxygen present in the hair can be removed and the original function of the permanent wave agent can be achieved. More preferably, after the permanent wave pretreatment agent is attached to the hair, the permanent wave treatment may be performed as it is without being washed away.

The means for attaching the permanent wave pretreatment agent to the hair is not particularly limited, and a known means can be employed in the same manner as the hair dyeing pretreatment agent described above.
Permanent wave intermediate treatment agent The permanent wave intermediate treatment agent according to the present invention is a preferred embodiment of the active oxygen radical removing agent for hair described above, and contains the above-mentioned composition for removing active oxygen radicals, It is characterized in that the permanent wave treatment is performed using a permanent wave agent, and the hair is attached to the hair after being washed with water.

  Active oxygen remains on the hair surface and inside after the permanent wave treatment, and it is difficult to remove it sufficiently by washing with water. On the other hand, when the permanent wave intermediate treatment agent is attached to the hair after washing with water, the active oxygen present in the hair is sufficiently removed, damage to the hair is suppressed, and as a result, the wave shape is maintained, and the permanent is removed. The wave is improved.

  Hair damage can also be reduced by adjusting the pH of the hair after permanent wave treatment. Furthermore, when γ-keratose is used as the active oxygen radical scavenger, after adhering to the hair surface, it can be expected to have a secondary effect that these penetrate into the hair and repair the hair damage.

  In addition, after attaching a permanent wave intermediate treatment agent to hair and performing an active oxygen removal process, it is good to wash the hair using the washing | cleaning agent containing surfactant, such as shampoo.

The means for attaching the permanent wave intermediate treatment agent to the hair is not particularly limited, and a known means can be adopted in the same manner as the hair dyeing pretreatment agent described above.
Permanent wave post-treatment agent The permanent wave post-treatment agent according to the present invention is a preferred embodiment of the active oxygen radical scavenger for hair described above, and comprises the above-mentioned composition for removing active oxygen radicals, A permanent wave treatment is performed on the hair using a permanent wave agent, followed by washing with water, and further, the hair is washed with a detergent containing a surfactant such as shampoo and water and then attached to the hair.

  Usually, the hair after the permanent wave treatment is washed with water, followed by washing with a detergent containing a surfactant such as shampoo, water, and if necessary, a hair rinse. Even after the washing treatment using this surfactant and also hair rinse, active oxygen may remain on the hair surface and inside.

  On the other hand, when a permanent wave post-treatment agent is attached to the hair after these washing treatments, the active oxygen present in the hair is sufficiently removed, and damage to the hair is suppressed. The shape is maintained and the durability of the permanent wave is improved. Hair damage can also be reduced by adjusting the pH of the hair after permanent wave treatment.

  Furthermore, when γ-keratose is used as the active oxygen radical scavenger, after adhering to the hair surface, it can be expected to have a secondary effect that these penetrate into the hair and repair the hair damage.

  The means for attaching the permanent wave post-treatment agent to the hair is not particularly limited, and a known means can be adopted in the same manner as the hair dyeing pre-treatment agent described above. After the permanent wave post-treatment agent is attached to the hair and the active oxygen removal treatment is performed, the hair may be washed with a detergent containing a surfactant such as water or shampoo, but the hair is not washed off. It may be dried.

  The permanent wave pretreatment agent, the permanent wave intermediate treatment agent, and the permanent wave post treatment agent each have an active oxygen removal ability, so that even if they are used alone, sufficient effects can be obtained. The effect can be further strengthened by using together.

EXAMPLES Hereinafter, although this invention is demonstrated further more concretely based on an Example, this invention is not limited to these Examples.
In the following examples, unless otherwise specified,% and parts are based on weight, and the monosaccharide is D-form. Moreover, each component used in the example is as follows.

Γ-type hydrolyzed keratin; 20% γ-keratose having an average molecular weight of 20,000 to 40,000, 10% butylene glycol, 0.17% parabens, the balance being water α-type hydrolyzed keratin; average molecular weight 25,000 ˜45,000 α-keratose 10%, urea 30%, butylene glycol 10%, sodium lauryl sulfate 5%, parabens 0.17%, the balance is water ・ hydrolyzed keratin; average molecular weight 400
・ Keratin; average molecular weight 40,000
・ Seaweed extract (1) ^{* 1} ; Fucoidan 1.5%, water 93.3%, butylene glycol 5%, parabens 0.2%
・ Seaweed extract (1) ^{* 2} ; Seaweed extract containing F-fucoidan 0.07% ・ Seaweed extract (1) ^{* 3} ; Hibamata extract 0.6%, water 54.4%, butylene glycol 45%
・ Red algae extract: 98.6% red algae extract (including 2.5-6% dry extract), butylene glycol 1
%, Preservative 0.4%
・ Seaweed extract (4); Red algae extract 0.554%, Brown algae extract 0.003%, Green algae extract 0.003%,
89.65% water, 10.0% butylene glycol
・ Hydrolyzed yeast extract; hydrolyzed yeast extract stock solution 2.5%, butylene glycol 97.5%
・ Yeast extract: Stock solution of yeast extract 0.37%, water 69.63%, butylene glycol 25%, glycerin 5%
-Eucalyptus extract; Eucalyptus extract stock solution 0.6%, Butylene glycol 49.7%, Water 49.7%
・ Rosemary extract: 0.6% rosemary extract stock solution, 49.7% butylene glycol,
Water 49.7%
[Test Example 1]
Active oxygen radical scavenger confirmation test 1
Using the XYZ weak light emission mechanism, the active oxygen removal ability of γ-keratose was evaluated.

Specifically, hydrogen peroxide (1% 3% hydrogen peroxide water) as X (active oxygen species), γ-keratose (γ-type hydrolyzed keratin 1 ml), Z (mediator) as Y (active oxygen removing substance) Using potassium bicarbonate (1 ml of 80 mM aqueous solution), mixing them at room temperature, and using a microluminescence analyzer (C8801; manufactured by Hamamatsu Photonics) to calculate the photon amount per second (counts / sec) Measurement was made to determine the integrated value for 10 minutes, and this was taken as the light emission amount.

Furthermore, using 1 ml of ion-exchanged water as Y as a blank, the amount of luminescence was measured and compared in the same manner as described above.
As a result, the amount of luminescence when γ-keratose was used was 130251826 compared to the amount of luminescence 2771764 when ion-exchanged water was used, confirming the active oxygen removal ability of γ-keratose.

[Test Example 2]
Active oxygen radical scavenger active oxygen removal ability confirmation test 2
The amount of luminescence was evaluated in the same manner as in Test Example 1 except that 1 ml of eucalyptus extract was used as Y.

As a result, the amount of luminescence when eucalyptus extract was used was 56025688, and the ability of eucalyptus extract to remove active oxygen was confirmed.
[Test Example 3]
Reactive oxygen removal ability confirmation test 3 of active oxygen radical scavenger
The amount of luminescence was evaluated in the same manner as in Test Example 1 except that 1 ml of rosemary extract was used as Y.

As a result, when the rosemary extract was used, the amount of luminescence was 31745123, and the active oxygen removal ability of the rosemary extract was confirmed.
[Test Example 4]
Test for confirming the effect of improving the active oxygen removal ability of α substances 1
Test Example 1 except that γ-keratose (1 ml of a 5% aqueous solution of γ-type hydrolyzed keratin) and 1 ml of a 10% aqueous solution of various monosaccharides (fructose, glucose, mannose, xylose, galactose) were used as Y. The amount of luminescence was evaluated in the same manner as described above.

Further, when Y is used as 1 ml of 5% aqueous solution of γ-type hydrolyzed keratin and 1 ml of ion-exchanged water, Y is used as 1 ml of 10% aqueous solution of various monosaccharides and 1 m of ion-exchanged water.
The amount of luminescence was measured and compared in the same manner as in Test Example 1, with each of l used as a blank.

  The results are shown in Table 1.

As is apparent from Table 1, various monosaccharides synergistically improved the active oxygen removal ability of γ-keratose, which is an active oxygen radical scavenger, as an α substance.
Then, instead of the various monosaccharides, 1 ml of 1% aqueous solution and 1 ml of 10% aqueous solution of D-fucose and L-fucose were used as monosaccharides, and 5% aqueous solution of the above-mentioned γ-type hydrolyzed keratin as a blank for Y. The amount of luminescence was measured in the same manner as in Test Example 1 except that 1 ml and 1 ml of ion-exchanged water were used, the number of samples was three, and the average value of these samples was obtained.

  The results are shown in Table 2.

As is clear from Table 2, fucose synergistically improved the ability to remove active oxygen of γ-keratose, which is an active oxygen radical scavenger, as an α substance in both D and L forms.
[Test Example 5]
Confirmation test 2 for improving the active oxygen removal ability of α substance
The amount of luminescence was evaluated in the same manner as in Test Example 1, except that 1 ml of a 1% or 5% aqueous solution of eucalyptus extract and 1 ml of a 10% aqueous solution of galactose were used as Y.

Further, when 1 ml of 1% aqueous solution of the eucalyptus extract and 1 ml of ion exchange water are used as Y, or 1 ml of 5% aqueous solution of the eucalyptus extract and 1 ml of ion exchange water, and 1 ml of 10% aqueous solution of galactose and ion exchange water as Y. The amount of luminescence was measured and compared in the same manner as in Test Example 1 using 1 ml as a blank.

  The results are shown in Table 3.

As is apparent from Table 3, galactose synergistically improved the active oxygen removal ability of the eucalyptus extract, which is an active oxygen radical scavenger, as an α substance.
[Test Example 6]
Test to confirm the effect of improving the active oxygen removal ability of α substance 3
In addition to Y, γ-keratose (1 ml of 5% aqueous solution of γ-type hydrolyzed keratin) and seaweed extract (1) (commercially available 3 types) according to cosmetic varieties, or 1 ml of commercially available red algae extract are used. Were evaluated in the same manner as in Test Example 1.

  Furthermore, when using 1 ml of 5% aqueous solution of γ-type hydrolyzed keratin and 1 ml of ion-exchanged water as Y, and using 1 ml of various seaweed extracts and 1 ml of ion-exchanged water as Y, respectively, test examples The amount of luminescence was measured and compared in the same manner as in 1.

  The results are shown in Table 4.

  As is clear from Table 4, seaweed extract (1) (3 species) synergistically improved the ability to remove active oxygen radical γ-keratose, which is an active oxygen radical scavenger, as an α substance. It turns out that it does not have the improvement effect of the active oxygen removal ability of (gamma) -keratose by itself.

[Test Example 7]
Test to confirm the effect of improving the active oxygen removal ability of α substance 4
The amount of luminescence was evaluated in the same manner as in Test Example 1 except that γ-keratose (1 ml of a 5% aqueous solution of γ-type hydrolyzed keratin) and 1 ml of hydrolyzed yeast extract or 1 ml of yeast extract were used as Y.

  Furthermore, when Y is used as 1 ml of 5% aqueous solution of γ-type hydrolyzed keratin and 1 ml of ion-exchanged water, and Y is used as 1 ml of hydrolyzed yeast extract or 1 ml of yeast extract and 1 ml of ion-exchanged water, respectively. As a blank, the amount of luminescence was measured and compared in the same manner as in Test Example 1.

  The results are shown in Table 5.

  As apparent from Table 5, this hydrolyzed yeast extract synergistically improves the active oxygen removal ability of γ-keratose, which is an active oxygen radical scavenger, as an α substance, and this yeast extract slightly improves the active oxygen removal ability. did.

[Examples 1 to 26]
According to the composition of Table 6, the composition obtained by mixing each component (pH adjusted to 5.5) was used as a pre-dyeing agent and a post-dyeing agent. ) Color retention, (2) damage, and (3) residual active oxygen were evaluated.

(1) Evaluation of color lasting Using a commercially available hair bundle of 100% white hair, before applying oxidative hair dyeing, apply each hair dye pretreatment agent,
Leave for 5 minutes and towel dry.

Thereafter, hair dyeing treatment was carried out using a commercially available medium-lightness red-brown oxidative hair dye according to a conventional method, and a hair bundle immediately after dyeing was obtained.
Next, the hair bundle immediately after dyeing was repeatedly washed 7 times and dried seven times to obtain a hair bundle after the fading test.

A color meter (MINOLTA) is used for the hair bundle immediately after dyeing and for the hair bundle after the fading test.
The Lab value was measured with CR-200), and the difference ΔE (delta E) was determined and evaluated based on the following evaluation criteria.

Evaluation criteria: ◎ △ E (Delta E) value is less than 0 ~ 2.0
○ △ E (Delta E) value is 2.0 or more and less than 3.0
▲ △ E (Delta E) value is 3.0 or more and less than 5.5
△ △ E (Delta E) value is 5.5 or more and less than 11.0
× △ E (Delta E) value is 11.0 or more
(2) Evaluation of damage Using a commercially available 30 cm black hair bundle, damaged hair which was damaged by powder bleaching treatment was used.

Each hair dye pretreatment agent was applied to the damaged hair, left for 5 minutes, and towel-dried.
Then, using a commercially available red-brown oxidative hair dye, the hair was dyed according to a conventional method and washed with water.

Thereafter, the breaking strength of the hair was measured using a Kato Tech tensile tester. Evaluation was made based on the following evaluation criteria.
As a blank, the breaking strength of the undyed hair was 14.06 kgf / mm ² . The breaking strength of the hair dyed without using the hair dye pretreatment agent was 11.73 kgf / mm ² .

Evaluation criteria: ○ Breaking strength is less than 1kgf / mm ² compared to untreated hair
△ breaking strength as compared to untreated hair, reduction of less than 1 kgf / mm ² or more ~2kgf / mm ²
× Breaking strength is 2kgf / mm ² lower than untreated hair
(3) Evaluation of residual active oxygen As a simple method for measuring residual active oxygen, a method of applying a hydrogen peroxide concentration test paper (manufactured by Hiejiang Chemical Co., Ltd.) to the hair to be measured was adopted.

  A commercially available 30 cm black hair bundle was dyed with a medium-light red-brown oxidative hair dye by a conventional method, and then washed with water. Thereafter, each hair dye post-treatment agent was applied to the towel-dried hair bundle, left for 2 minutes, and then washed with water.

Next, the hydrogen peroxide concentration test paper was attached to the wet hair bundle, and then the color of the test paper was confirmed and evaluated according to the following evaluation criteria.
Evaluation criteria: ◎ 0ppm
○ Over 0ppm to less than 2ppm
▲ 2ppm to less than 5ppm
△ 5ppm or more to less than 10ppm
× 10ppm to less than 25ppm
XX 25ppm or more In addition, active oxygen of 25ppm or more remained on the hair surface only by washing with water after the hair dyeing treatment without applying the hair dyeing treatment agent.

Further, when the hair dyeing treatment agent was not applied and the hair was washed with a commercially available shampoo and treatment, 5 ppm to less than 10 ppm of active oxygen remained on the hair surface.
Further, when γ-type hydrolyzed keratin or eucalyptus extract described in Table 6 was used alone as a hair dyeing treatment, 2 ppm to less than 5 ppm of active oxygen remained.

  These evaluation results are shown in Table 6. The unit of numerical values in the table is g.

  From Table 6, according to the compositions of Examples 1 to 26, the active oxygen on the hair surface after the oxidative hair dyeing treatment is effectively removed, and the hair after the oxidative hair dyeing treatment has good color and damage. From these results, it can be seen that not only the hair surface but also active oxygen inside the hair is effectively removed.

In addition, even if the composition shown in Table 6 is used as a hair dyeing intermediate (oxidative hair dyeing treatment->standing->washing-> hair dyeing intermediate application-> water washing treatment), a hair dyeing pretreatment agent or a hair dyeing treatment The effect was similar to that of the agent.
[Comparative Examples 1 to 20]
Except according to the composition of Table 7, a composition was obtained in the same manner as in Examples 1 to 26 (pH was adjusted to 5.5), and this was used as a pre-dyeing agent and a post-dyeing agent. (1) Color retention, (2) damage, and (3) residual active oxygen were evaluated in the same manner.

  The results are shown in Table 7. The unit of numerical values in the table is g.

[Examples 27 to 52]
A composition was obtained in the same manner as in Examples 1 to 26 except that the composition in Table 8 was followed (pH was adjusted to 5.5), and this was used as a shampoo. Except for using the shampoo instead of the water washing treatment without using the hair dyeing pretreatment agent and the hair dyeing treatment agent, the same as in Examples 1 to 26, (1) Color retention, And (3) Residual active oxygen was evaluated.

  The results are shown in Table 8. The unit of numerical values in the table is g.

  From Table 8, according to the compositions of Examples 27 to 52, the active oxygen on the hair surface after the oxidative hair dyeing treatment is effectively removed, and the color of the hair after the oxidative hair dyeing treatment is good. It can be seen that not only the hair surface but also active oxygen inside the hair is effectively removed.

[Comparative Examples 21 to 40]
Except according to the composition of Table 9, a composition was obtained in the same manner as in Examples 27 to 52 (pH was adjusted to 5.5), this was used as a shampoo, and as in Examples 27 to 52. , (1) color retention, and (3) residual active oxygen.

  The results are shown in Table 9. The unit of numerical values in the table is g.

[Examples 53 to 78]
A composition was obtained in the same manner as in Examples 1 to 26 except that the composition shown in Table 10 was used (pH was adjusted to 4.0), and this was used as a treatment (hair rinse). In the same manner as in Examples 1 to 26 except that the pre-dyeing agent and the post-dyeing agent were not used, and instead of only the water washing treatment, the water washing treatment using the treatment was performed after each water washing treatment, ( It was evaluated for 1) color retention and (3) residual active oxygen.

  The results are shown in Table 10. The unit of numerical values in the table is g.

  From Table 10, according to the compositions of Examples 53 to 78, the active oxygen on the hair surface after the oxidative hair dyeing treatment is effectively removed, and the color of the hair after the oxidative hair dyeing treatment is good. It can be seen that not only the hair surface but also active oxygen inside the hair is effectively removed.

[Comparative Examples 41-60]
Except according to the composition of Table 11, compositions were obtained in the same manner as in Examples 53 to 78 (pH was adjusted to 4.0) and used as a treatment (hair rinse). Similarly, (1) color retention and (3) residual active oxygen were evaluated.

  The results are shown in Table 11. The unit of numerical values in the table is g.

Claims (14)

  A composition for removing active oxygen radicals, comprising at least one active oxygen radical scavenger selected from the group consisting of γ-keratose, eucalyptus extract, and rosemary extract, and a reducing sugar.   Active oxygen comprising at least one active oxygen radical scavenger selected from the group consisting of γ-keratose, eucalyptus extract, and rosemary extract, and a polysaccharide having at least a structural unit derived from fucose A composition for removing radicals. For removing active oxygen radicals, comprising at least one active oxygen radical scavenger selected from the group consisting of γ-keratose, eucalyptus extract and rosemary extract, and a yeast extract obtained from yeast (Saccharomyces) Composition.   The composition for removing active oxygen radicals according to any one of claims 1 to 3, wherein the γ-keratose has an average molecular weight of 20,000 to 40,000.   The composition for removing active radicals according to claim 1 or 4, wherein the reducing sugar is at least one selected from the group consisting of glucose, fructose, fucose, mannose, xylose and galactose.   The composition for removing active radicals according to claim 2 or 4, wherein the polysaccharide is derived from a seaweed extract.   The composition for removing active radicals according to claim 2 or 4, wherein the polysaccharide is fucoidan.   The composition for removing active oxygen radicals according to any one of claims 1 to 7, wherein the composition is used as a hair active oxygen radical removing agent.   It contains the composition for removing active oxygen radicals according to any one of claims 1 to 7, and is attached to the hair before the treatment before the hair is dyed using the oxidative hair dye. A hair dyeing pretreatment agent characterized by that.   The composition for removing active oxygen radicals according to any one of claims 1 to 7, wherein the hair is dyed with an oxidative hair dye and washed with water, and then attached to the hair. Hair dye intermediate treatment agent characterized by.   It contains the composition for removing active oxygen radicals according to any one of claims 1 to 7, and after hair is dyed with an oxidative hair dye, it is washed with water, and further a surfactant and water. A post-dyeing agent characterized by being attached to hair after washing with hair.   The composition for removing active oxygen radicals according to any one of claims 1 to 7 is attached to the hair before treatment before the permanent wave treatment using the permanent wave agent. A permanent wave pretreatment agent characterized by   The composition for removing active oxygen radicals according to any one of claims 1 to 7, wherein the hair is permanently wave-treated using a permanent wave agent and adhered to the hair after being washed with water. A permanent wave intermediate treatment agent.   The composition for removing active oxygen radicals according to any one of claims 1 to 7, wherein the hair is permanently waved using a permanent wave agent, then washed with water, and further with a surfactant and water. A permanent wave post-treatment agent, which is attached to the hair after washing.