JP2007001584A - Bag for sterilization - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a bag for sterilization which makes a package easily openable by hands under a condition that a stored article is held, facilitates the extraction of the stored article, prevents the stored article from falling down, and is excellent in hygienic properties. <P>SOLUTION: The bag 10 for sterilization is constituted so that a gas-impermeable sheet or film 1 prepared by stacking a supporting substrate layer 11 and a heat-sealable layer 12 on the inner face of the supporting substrate layer is folded at two positions to make a section to be an approximately C-shape, a sterilization paper 2 consisting of a gas-permeable material which allow no bacteria to pass through is applied on the inner face side of an opening part, piled up parts 7 of the side edge parts of the sterilization paper 2 and the side edge parts of the gas-impermeable sheet or film 1 are weakly sealed to form a weakly sealed parts 4 and to form a cylindrical shape, and the sealing parts 3 on the peripheral side parts of the bag are strongly sealed so as to pinch the upper and lower ends of the sterilization paper 2 within the inner face of the gas-impermeable sheet or film. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a medical instrument, a medical product, a microorganism testing instrument, a food container, and a container sterilization bag. More specifically, the present invention relates to a sterilization bag in which a package can be easily opened in a state in which the stored item is held, the stored item is easily taken out, and the hygiene property is excellent.

As shown in FIG. 4, the conventional sterilization bag 10 ′ has a breathable sheet 2 attached to at least a part of one open edge of a cylindrical body made of a heat-adherent non-breathable material 1. And the packaging bag for gas sterilization which heat-bonds the said open edge part in the state which hold | maintained the air permeability of this sheet | seat is proposed (for example, refer patent document 1).
Further, as shown in FIG. 5, the conventional sterilization bag 10 'is formed on a single body plate of a bag body made of a non-breathable sheet or film with a space between each other in the direction of the opening edge. A tape made of a breathable material that does not allow germs to pass therethrough is engraved on the inner side of the bag of the body plate so as to cover the plurality of cuts. The left and right ends of the tape are heat sealed to a non-breathable sheet or film with the bag left and right seals sandwiched between them, and both longitudinal peripheral portions of the tape are attached to the non-breathable sheet or film constituting the one-side body plate. A sterilization bag formed by heat sealing has been proposed (see, for example, Patent Document 2).
And in the state which accommodated contents, such as a medical instrument, such as a catheter and a syringe, in the above sterilization bags, an opening part is heat-sealed and sealed, and it is ethylene oxide gas (henceforth "EOG") in an autoclave. .) Sterilization and steam sterilization can be performed.
JP 51-72593 A Japanese Utility Model Publication No. 63-88338

However, in conventional sterilization bags, when a bag is opened for a consumer to take out the contents in the bag, the non-breathable sheet or Even if the film cannot be easily torn by hand, and a notch (notch for opening) is provided in the bag, heat sealing is performed by stacking a breathable sheet (sterilized paper, nonwoven fabric, etc.) and a non-breathable sheet. In the heat seal part, it is necessary to peel off the heat seal part with a strong force, so it is difficult to open, and as a result, it is difficult to take the contents out of the bag by tearing in the crotch state, or the contents in the bag There was a problem that things spilled or scattered outside the bag.
Also, when opening the package, when tearing with the notch as the starting point, it is necessary to pick and tear the notch with both hands, so both hands will be blocked, so the contents are held so that the contents do not fall There was a problem that it was difficult to open the bag.
Furthermore, if notched chips and chips on the cut surface are mistakenly mixed into the bag, it causes foreign matters and has a problem in terms of hygiene.
In addition, when opening the package, it can be opened using a bag, but it is necessary to manage the bag while maintaining its hygiene, and there is a problem that the contents may be accidentally cut. there were.

  It is an object of the present invention to provide a sterilization bag that can be easily opened by hand while holding the stored items, can easily take out the stored items, does not drop the stored items, and is excellent in gas barrier properties and hygiene. It is to provide.

  Therefore, in order to solve the above-described problem, the sterilization bag according to the present invention is formed by folding two portions of a non-breathable sheet or film in which a support base layer and a heat sealable layer are laminated on the inner surface of the support base layer. The cross section is substantially C-shaped, and sterilized paper made of a breathable material that does not allow bacteria to pass is applied to the inner surface side of the opening, and the side edge of the sterilized paper and the side edge of the non-breathable sheet or film are overlapped. The bag is heat sealed at the periphery of the bag, with a weak seal part formed into a cylindrical shape, and the upper and lower ends of the sterilized paper sandwiched between the non-breathable sheet or the inner surface of the film. .

  Further, in the sterilization bag of the present invention, in the above-described configuration, among the left and right ends of the non-breathable sheet or film constituting the one-side body plate overlaid on both longitudinal peripheral portions of the sterilized paper, It is the structure which has the seal part weakly sealed in the state which left the non-seal part in at least one.

  In the sterilization bag of the present invention, the heat-sealable layer constituting the non-breathable sheet or film is an easy peel heat-sealable layer.

The bag for sterilization of the present invention is a sterilized paper, which is a non-breathable sheet or film that constitutes one side of the sterilized paper and the one side shell plate when the package is opened after sterilization with the contents stored in the bag. Because it is weakly sealed (easy peel seal) over the entire width in the longitudinal direction, it can be easily opened by hand, and can be opened while holding the stored item with one hand. It is possible to prevent accidental dropping.
Further, since the sterilization bag of the present invention can be opened over the entire width of the sterilized paper, the opening can be made wider than opening from the notch as a starting point, so that the contents can be easily taken out. Has the advantage.
In addition, since the sterilization bag of the present invention can be opened without using a bag or the like, there is an advantage that chips and the like are not mixed as foreign matter in the bag and are excellent in hygiene.
In addition, the sterilization bag of the present invention has an unsealed portion at the end of the non-breathable sheet constituting the one-sided body plate superimposed with the sterilized paper, so that the unsealed portion can be easily picked and opened by hand. Has the advantage of being able to.

Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.
FIG. 1 is a schematic view showing an embodiment of a sterilization bag according to the present invention, (a) is a plan view, and (b) is a cross-sectional view taken along the line AA of FIG. 1 (a). (C) is sectional drawing of the laminated body which shows one Example of the non-breathable sheet | seat or film which comprises the sterilization bag which concerns on this invention, (d) is the non-structure which comprises the sterilization bag which concerns on this invention FIG. 2 is a cross-sectional view of a laminate according to another embodiment of a breathable sheet or film, FIG. 2 is a cross-sectional view showing an example of a sterilization package according to the present invention, and FIG. 3 is a sterilization according to the present invention. It is a schematic sectional drawing which shows the usage example of a packaging bag, (a) Before opening part formation, (b) After opening part formation, (c) After storage of contents, (d) It is explanatory drawing after opening.
As shown in FIG. 1A, the sterilization bag according to the present invention includes a non-breathable sheet or film 1 and a sterilized paper 2 made of a breathable material that does not allow bacteria to pass through.
The non-breathable sheet or film 1 constituting the sterilization bag according to the present invention is a laminate in which a support base material layer 11 and a heat sealable layer 12 are sequentially laminated from the outside as shown in FIG. As a film having a basic configuration of a sheet or film, the film used for the heat-sealable layer 12 is a so-called easy peel sealant film in which the heat-seal between the surfaces of the heat-sealable layer 12 is weakly sealed, or heat-sealable A polyethylene film, a polypropylene film, an ionomer film, an ethylene-vinyl acetate copolymer film, or the like in which the heat seal between the surfaces of the layer 12 becomes a strong seal can be used.
Moreover, as shown in FIG.1 (d), the intermediate | middle layer 13 can be provided in the interlayer of the support base material layer 11 and the heat-sealable layer 12 as needed.
In addition, the air-impermeable sheet or film 1 according to the present invention is not limited to the above-described layer configuration, and although not shown, for example, a printing layer may be formed on one side of the support base material layer 11, and the support An adhesive layer can be formed between the base material layer 11 and the heat-sealable layer 12, and a pinhole-resistant layer or the like can be provided as an intermediate layer as required.

As shown in FIG. 3 (a), the sterilization bag according to the present invention is folded with the heat-sealable layer 12 constituting the non-breathable film 1 as an inner surface, and the strip-like shape between the left and right ends. The sterilized paper 2 is applied to the inside, the left and right ends of the sterilized paper are sandwiched between the bag left and right seals, and the bag periphery is heat-sealed to form a bag shape. After the portion overlapped with No. 1 was sealed with an easy peel seal in both longitudinal directions of the sterilized paper, the bag end was cut off along the line BB, and an opening was provided as shown in FIG. Is.
The above-mentioned bag body is an easy peel with the non-sealed portion 6 left at least at one of the left and right end edges of the non-breathable film 1 superimposed on the left and right ends of the sterilized paper 2. Sealing is more preferable in that the unsealed portion 6 at the tip of the non-breathable film 1 can be easily picked by hand when the bag is opened.

Next, in the present invention, the packaging material according to the present invention as described above, the material constituting the packaging bag, and the production method thereof will be described. First, the non-breathable film 1 is sterilized by autoclave or The support base material layer 11 constituting the non-breathable film 1 must be capable of being sterilized with ethylene oxide gas. Examples of the support base material layer 11 include polyamide resin, polyester resin, low density polyethylene resin, medium density polyethylene resin, and high density polyethylene. A film or sheet of resin, polypropylene resin, cellophane or the like may be a single support substrate, or may be a composite support substrate formed by combining two or more types of support substrates.
In the present invention, the above-mentioned base film layer has, for example, a desired print pattern such as a letter, a figure, a symbol, a pattern, a pattern, etc. using an ordinary ink composition for offset printing, gravure printing, flexographic printing, etc. Printing may be performed on one side of the support base material layer 11 as necessary by a normal printing method such as printing, letterpress printing, silk screen printing, or the like.
The thickness of the film is about 5 to 100 μm, preferably about 7 to 50 μm.

Next, in the present invention, the heat-sealable layer 12 constituting the non-breathable film 1 can be sterilized by autoclave or ethylene oxide gas, and reliably seals the opening of the sterilization bag. The non-breathable film 1 and the sterilized paper 2 may be heat-bonded to such an extent that they can be easily peeled off when the sterilization bag is opened.
As a method for weakly sealing the sterilized paper and the non-breathable film, there is a method of combining a non-breathable film material having weak sealability with the sterilized paper material.
For example, when the material of the sterilized paper is polyethylene, it is preferable to use an easy peel film or an unstretched polypropylene film for the heat sealable layer 12 with respect to polyethylene.
The resin constituting the easy peel film has a structure in which the heat bonding surface is made of a special polymer alloy of polyethylene, polypropylene, and polystyrene. By micro-dispersing the adhesive / non-adhesive resin of special polymer alloy, the micro-dispersion layer appears at the interface by heat and pressure in the heat sealing process, and the strong heat fusion part with the adherend material is controlled on the micro order. The heat seal strength is controlled, and it is a microscopically cohesive failure of a complete seal, and macroscopically exhibits a clean peeling surface that is interfacial peeling.
Specifically, for example, “IMX” manufactured by J-Film Co., Ltd. can be suitably used as the easy peel film.
When the material of the sterilized paper is paper mainly composed of pulp, it is preferable to use polyethylene, unstretched polypropylene, ethylene-vinyl acetate copolymer, ionomer or the like as the material of the heat sealable layer 12. Further, there is a method of forming the heat-sealable layer 12 partially or entirely at a desired position of the support base material layer 11.
The above easy peel heat seal layer is formed by laminating a resin layer such as polyethylene resin or polypropylene resin, or modified polyolefin heat seal adhesive, acrylic heat seal adhesive, polyester heat seal Adhesive, modified polyester heat seal adhesive, ethyl vinyl alcohol heat seal adhesive, polyvinyl alcohol heat seal adhesive, vinyl acetate heat seal adhesive, hydrochloric acid / vinyl acetate copolymer heat seal A coating material such as an adhesive, a vinyl chloride heat sealable adhesive, or a polyether heat sealable adhesive can be formed.
The thickness of the resin layer is preferably about 10 to 30 μm, and the film thickness of the coating material is preferably about 1 to 10 μm.
Although it does not specifically limit as a formation method of said coating material, For example, formation methods, such as a gravure coat method, a reverse coat method, a kiss coat method, a die coat method, a metal ring bar coat method, can be used.
In the present invention, the easy peel heat-seal layer may be an easy peel film layer or an easy peel resin layer. Among them, the easy peel film layer has a more stable release surface. Is more preferable.

  To the resin forming each layer of the non-breathable film 1 according to the present invention, additives such as a lubricant, an antioxidant, and an antistatic agent can be added at any time as long as the object of the present invention is not impaired. .

In the present invention, as the sterilized paper 2 made of a breathable material that does not allow passage of bacteria, for example, those made of uncoated paper, non-woven fabric, Japanese paper and the like can be used.
As the nonwoven fabric, for example, Tyvek (manufactured by DuPont Japan Limited), Luxer (manufactured by Asahi Kasei Kogyo Co., Ltd.) and the like can be used.
In addition, polyethylene, polypropylene such as non-woven fabric, Japanese paper, etc. with holes perforated, Nippon Oil Co., Ltd. Nisseki Warif, Kurashiki Boseki Co., Ltd., Shin Nippon Sof Co., Ltd., Sofcross, etc. What laminated | stacked the net-shaped reinforcement which consists of etc. can be used.
The thickness of the sterilized paper 2 can be appropriately selected in consideration of the temperature condition during sterilization (usually 50 to 121 ° C.) because the aeration rate can be changed.

Next, in the present invention, the heat seal method includes, for example, a bar seal, a rotary roll seal, a belt seal, an impulse seal, a high frequency seal, and an ultrasonic seal. It can be performed by a method such as
Further, the sterilization bag according to the present invention can be easily opened by hand that the adhesive strength between the non-breathable film 1 (heat seal surface) and the sterilized paper 2 is in the range of 3N / 15mm to 15N / 15mm. It is preferable because it is easy to be peeled off at the stage of packaging, sterilization and distribution.

  The method for producing a sterilization bag according to the present invention is not particularly limited. For example, a non-breathable film 1 is folded along a plate and wound around a plate using a pillow bag making machine. Molded in a C shape, sterilized paper 2 is applied from the inside between the left and right side edges of the non-breathable film 1 and the plate, and the left and right ends of the sterilized paper are sandwiched between the left and right seals of the non-breathable film 1 In this state, the sealing part 4 of the non-breathable film 1 was weakly sealed to form a cylinder, and the sealing part 4 around the bag was heat sealed to produce a sealed bag body. Thereafter, when filling the contents, either one of the bent portions on both sides can be cut to form the filling opening 8.

In the present invention, the sterilization bag 10 manufactured as described above stores the contents from the opening at the upper end, heat seals the upper end and seals it, then performs EOG sterilization or steam sterilization, It can be distributed in the market.
When opening the above sterilization bag and taking out the contents, hold the contents with one hand, and with the other hand, pick the non-sealed part of the non-breathable sheet with your hand and open it easily. Therefore, it is possible to prevent the contents from falling, and since it can be opened over the entire width of the sterilized paper, the opening can be widened so that the contents can be easily taken out. Therefore, it can be used for packaging of solid materials such as medical instruments, medical products, foods, cosmetics, etc., and is particularly effective for sterilization of medical instruments such as catheters, disposable sets for artificial hearts, syringes, etc. In addition, it is also very useful for foods having a sterilization treatment such as spices, komaki for growing shiitake mushrooms, bacteria culture containers, and the like.
In addition, if a so-called easy peel sealant film in which the heat seal between the heat sealable layers 12 becomes a weak seal is used as the film of the heat sealable layer 12, the heat seal portion between the air-impermeable films 1 can also be opened. It is easy to take out the large contents, and if the film that heat seals between the heat-sealable layers 12 becomes a strong seal, the heat-sealed part between the non-breathable films 1 cannot be opened. The contents are not easily spilled when many are packed.
Further, if the non-breathable film 1 on the folding side, which is an extension of the body, is opened instead of the opening side at the time of bag making, an easy peel sealant film was used as the film of the heat sealable layer 12. In this case, even if the weak seal part is completely peeled off, a film piece does not occur, which is suitable for applications requiring strict management of unnecessary objects such as an operating room.

Next, the present invention will be described in further detail with reference to examples.
A biaxially stretched polyethylene terephthalate film (product name “E5102” manufactured by Toyobo Co., Ltd.) having a thickness of 12 μm is used as the resin film for the supporting base layer 11, and an easy peel sealant having a thickness of 50 μm is used as the heat sealable layer 12. A film (product name “IMX” manufactured by J-Film Co., Ltd.) is prepared and laminated as an adhesive via a urethane resin-based two-component mixed adhesive (application amount is 3 g / m ² ). A non-breathable film 1 of a biaxially stretched polyethylene terephthalate film (12 μm) / 2-component mixed laminate adhesive layer / a face-to-face easy peel sealant film (50 μm) was produced.
Moreover, Tyvek 1073B (manufactured by DuPont) having a basis weight of 73 g / m ² was prepared as sterilized paper (breathable sheet) 2.
Then, the side edge of the non-woven fabric 2 and the side edge of the non-breathable sheet 1 are overlapped so that the heat-sealable layer 12 of the non-breathable sheet 1 obtained above faces each other, and an impulse sealer (Fuji Impulse Co., Ltd. FA-450-5W) was used, and heat sealed with a seal width of 5 mm in heating for 1.0 second and cooling for 1.3 seconds to form a cylindrical shape. A bag for sterilization according to the present invention as shown in FIG. 1 (a) was manufactured by heat-sealing and sealing the periphery of the bag under the same heat-sealing conditions as described above so as to be sandwiched between the inner surface of the breathable sheet or film. .
And as shown to Fig.3 (a), one side of the obtained sterilization bag which concerns on this invention is cut by a BB line, and it is obtained by cutting as shown in FIG.3 (b). 4 syringes are stored as contents from the opened opening 8, and the opening 8 is heat-sealed to form a heat-sealed portion 9 and sealed as shown in FIG. 3C, and sterilization according to the present invention. The packaging body 20 was manufactured.
The sterilization package 20 according to the present invention obtained above is put into an EOG indicator (manufactured by ATI), and then sterilized under the conditions of EOG humidity, 20%, temperature, 60 ° C., atmospheric pressure, and 0.1 MPa. Thereafter, EOG in the bag was forcibly released through the sterilized paper (breathable sheet) 2 under vacuum.
As shown in FIG. 1 (c), the sterilized packaging body 20 thus obtained is sterilized and processed with the other hand while holding the syringe as the contents when opened. By easily picking and peeling off the non-seal part 6 at the tip of the non-breathable film 1, it can be easily peeled off by cohesive failure of the seal parts 3, 4, and it is stable without dropping the contents. In addition, since it can be opened over the entire width of the sterilized paper in the longitudinal direction, the opening can be widened, so that the contents can be easily taken out.

A biaxially stretched polyethylene terephthalate film (product name “E5102” manufactured by Toyobo Co., Ltd.) having a thickness of 12 μm is used as a resin film for the supporting base material layer 11, and a biaxially stretched polyamide film (product name “product name“ Bonyl W (manufactured by Kojin Co., Ltd.) was used, and a 60 μm thick polypropylene film (product name “P1147” manufactured by Toyobo Co., Ltd.) was prepared as the heat-sealable layer 12, and an urethane resin-based adhesive was used as the adhesive. Laminate via a two-component mixed laminate adhesive (coating amount: 3 g / m ² ), layer structure, biaxially stretched polyethylene terephthalate film (12 μm) / 2 component mixed laminate adhesive layer / biaxially stretched polyamide film ( 15 μm) / 2 liquid mixed laminate adhesive layer / polypropylene film (60 μm) non-breathable film 1 was produced. .
Moreover, MEP-70P (made by Kojin Co., Ltd.) having a basis weight of 70 g / m ² was prepared as the sterilized paper (breathable sheet) 2.
And the side edge part of the said nonwoven fabric 2 and the side edge part of the non-breathable sheet 1 are piled up so that the heat-sealable layer 12 of the non-breathable sheet 1 obtained above may oppose, and sealing temperature Heat seal with a seal width of 10 mm under sealing conditions of 180 ° C., sealing pressure of 0.2 MPa, and sealing time of 2.0 seconds to form a cylinder. Further, the upper and lower ends of the sterilized paper are the inner surfaces of a non-breathable sheet or film. As shown in FIG. 1 (a), the bag for sterilization according to the present invention was manufactured.
And as shown to Fig.3 (a), one side of the obtained sterilization bag which concerns on this invention is cut by a BB line, and it is obtained by cutting as shown in FIG.3 (b). From the opening 8, 10 distilled water contained in a 5 ml vial was stored as the contents, and as shown in FIG. 3 (c), the opening 8 was heat sealed to form a heat seal portion 9 and sealed, A sterilization package 20 according to the present invention was produced.
The sterilization package 20 according to the present invention obtained above was sterilized in an autoclave under the conditions of temperature, 121 ° C., time, and 20 minutes, and then the moisture in the bag was removed by drying in an oven at 60 ° C.
As shown in FIG. 1 (d), the sterilized packaging body 20 obtained in this manner is in a state of holding distilled water in a 5 ml vial as the contents with one hand when opening, The non-sealable portion 6 at the tip of the non-breathable film 1 can be easily picked and peeled off with the other hand, and can be easily peeled off by interfacial peeling of the seal portion 4, and the opposing heat-sealable layer Since the heat seal part between the 12 is a strong seal, the one-side body part 6 will not be peeled except for the heat seal part with the sterilized paper. Can be taken out in a stable state without spilling out of the bag.

BRIEF DESCRIPTION OF THE DRAWINGS It is the schematic which shows one Example of the sterilization bag based on this invention, (a) is a top view, (b) is sectional drawing in the AA of FIG. 1 (a), (c) BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a cross-sectional view of a laminate showing one embodiment of a non-breathable sheet or film constituting a sterilization bag according to the present invention, and (d) is a non-breathable sheet or structuring a sterilization bag according to the present invention It is sectional drawing of the laminated body of another aspect of a film. It is sectional drawing which shows one Example of the sterilization packaging body which concerns on this invention. It is a schematic sectional drawing which shows the usage example of the packaging bag for sterilization which concerns on this invention, (a) Before opening part formation, (b) After opening part formation, (c) After storing contents, (d) After opening FIG. It is the schematic which illustrates the form of the conventional sterilization bag. It is the schematic which illustrates another form of the conventional sterilization bag.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Non-breathable sheet or film 2 Sterile paper 3 Seal part around bag 4 Slightly sealed part between the peripheral part in the longitudinal direction of sterilized paper and non-breathable sheet or film 5 One side body part 6 Non-seal part (pick part)
7 Overlapping part 8 Opening 9 Sealing part (strong sealing part)
10 Sterilization bag 10 'of the present invention Conventional sterilization bag 11 Support base material layer 12 Heat-sealable layer 13 Intermediate layer 14 Notch 15 Cut (slit)
20 Packaging M for Sterilization of the Present Invention Contents

Claims (3)

  A non-breathable sheet or film for laminating the support base material layer and the heat sealable layer on the inner surface of the support base material layer is folded at two places so as to have a substantially C-shaped cross section, and bacteria are not passed through the inner surface side of the opening. Apply sterilized paper made of a breathable material, form a weak seal part into a cylindrical shape by weakly sealing the overlapping part of the side edge of the sterilized paper and the side edge of the non-breathable sheet or film, and A sterilization bag obtained by heat-sealing the periphery of the bag with the upper and lower ends of the sterilized paper sandwiched between the non-breathable sheet or the inner surface of the film.   The sterilized paper was weakly sealed with at least one of the left and right ends of the non-breathable sheet or film constituting the one-sided body plate overlaid on both peripheral portions in the longitudinal direction, leaving at least one non-sealed portion. The sterilization bag according to claim 1, further comprising a seal portion. The sterilization bag according to claim 1, wherein the heat-sealable layer constituting the non-breathable sheet or film is an easy peel heat-sealable layer.

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