JP2005081087A - Rotary drive unit of centrifuge - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a rotary drive unit of a centrifuge that detects a blood leakage from the centrifuge and can assuredly prevent the blood from leaking out of the apparatus in case of the blood leakage. <P>SOLUTION: This unit has belt-shaped blood leakage sensors 16a and 16b on the inner circumference of a housing 11 at the height of a rotary seal section 54 and a height of a bottom section of a rotor 51 under the condition that the centrifuge 50 is housed in the housing 11. In addition, a projected component 19 and a recessed component 20 are formed on tangent surfaces 18a and 18b of lids 14a and 14b, respectively, and O rings 21 are placed on the outer circumference of the upper edge of the housing 11. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

  The present invention relates to a driving device for rotationally driving a centrifuge for separating blood into a plurality of blood components. More specifically, the present invention relates to a rotary drive device for a centrifuge that can accurately detect blood leakage from the centrifuge.

  In the case of blood collection, at present, component blood donation is performed for reasons such as effective use of blood and reduction of burden on donors. In this component blood donation, the collected blood is introduced into a centrifuge called a centrifuge bowl, the centrifuge is driven to rotate by a driving device, separated into each blood component by centrifugation, and only the necessary components are collected. The ingredients are returned to the blood donor.

  Here, the centrifugal separator is fixed to a rotational drive device and is rotationally driven. And as a system which fixes a centrifuge to a rotation drive device, there are a vacuum chuck system (for example, refer to patent documents 1) or a mechanical chuck system (for example, refer to patent documents 2). The centrifuge fixed to the rotational drive device by any method is rotationally driven by a motor provided in the rotational drive device.

  As shown in FIG. 6, such a rotation drive device 100 includes a cylindrical housing 101 for housing the centrifuge 50, a fixing base 102 for fixing the centrifuge 50, and a rotation of the fixing base 102. A motor 103 to be operated and a lid 104 provided on the upper portion of the housing 101 are provided. Further, on the inner peripheral surface of the housing 101, an interface sensor 105 for detecting the position of the interface of the blood component separated in the centrifuge 50, and blood for detecting blood leakage from the centrifuge 50 are provided. A leak sensor 106 is provided.

  Here, as shown in FIG. 7, the lid 104 includes half-divided lids 104 a and 104 b. The lids 104a and 104b rotate along the upper surface of the flange 101a formed at the upper end of the housing 101 with the hinge portion 107 as an axis. Then, as shown in FIG. 8, the lids 104 (104a, 104b) are closed by bringing the contact surfaces 108a, 108b of the lids 104a, 104b into close contact with each other.

  When the centrifuge 50 is set in such a rotary drive device 100, the lid 104 (104a, 104b) of the rotary drive device 100 is opened as shown in FIG. Then, the centrifuge 50 is inserted from above the rotary drive device 100, and the centrifuge 50 is accommodated in the housing 101. The bottom of the centrifuge 50 accommodated in the housing 101 is placed on the fixed base 102 and fixed. After that, as shown in FIG. 8, the lid 104 (104a, 104b) of the rotary drive device 100 is closed. Then, the fixed base 102 is rotated by driving the motor 103 of the rotation driving device 100. When the fixed base 102 rotates, the centrifuge 50 fixed to the fixed base 102 also rotates. Thereby, the blood introduced into the centrifuge 50 is centrifuged into a plurality of blood components.

  When the blood leaks from the centrifuge 50 during the rotation of the centrifuge 50 and the blood leak is detected by the blood leak sensor 106, the rotation drive of the motor 103 of the rotation drive device 100 is stopped and the centrifuge is centrifuged. The rotation of the separator 50 is stopped.

Japanese Patent Laid-Open No. 48-24358 (pages 1 and 2, FIG. 1) Japanese Patent Laid-Open No. 9-164343 (pages 4-5, FIG. 2)

  However, since the conventional centrifugal drive device 100 is provided with the blood leakage sensor 106 for detecting blood leakage from the centrifugal separator 50 only at one location, there is a possibility that a minute amount of blood leakage may not be detected. there were.

  Here, the state in which blood is leaking from the centrifuge 50 is considered to have some abnormality in the centrifuge 50. For example, there may be a case where blood leakage occurs because the function of the rotation seal portion 54 of the centrifuge 50 does not operate normally due to an installation error of the centrifuge 50 to the rotation drive device 100 or the like. If rotation driving of the centrifuge 50 is continued in such a state, the amount of blood leaking from the centrifuge 50 increases, and subsequent processing becomes difficult. For this reason, it is desired to detect a small amount of blood leakage from the centrifuge at an early stage.

  Further, in the conventional centrifuge drive device 100, when blood leaks from the centrifuge 50, blood may leak out of the apparatus. This is because when the half-divided lids 104a and 104b attached to the rotary drive device 100 are closed, the lids are in contact with each other and the sealing performance is poor, and the housing 101 and the lids 104a and 104b This is because no sealing mechanism is provided during the interval.

  Therefore, the present invention has been made to solve the above-described problems. In addition to accurately detecting blood leakage from the centrifuge, blood is leaked to the outside of the device when blood leakage occurs from the centrifuge. It is an object of the present invention to provide a rotary drive device for a centrifuge that can reliably prevent leakage.

  In order to solve the above problems, a centrifugal drive device for a centrifugal separator according to the present invention includes a rotor having a blood storage space therein, a stator having an inlet and an outlet communicating with the blood storage space, and the rotor. In a centrifuge rotation driving device that holds and rotates a centrifuge provided with a rotary seal portion that liquid-tightly seals the stator, a cylindrical housing that houses the centrifuge, A lid that is divided in half to open and close the upper opening, a disk-shaped fixing base that holds the centrifuge, a motor that rotates the fixing base, and a blood leak from the centrifuge Therefore, it has a strip-shaped blood leak sensor arranged on the inner wall surface of the housing.

  This centrifugal drive device accommodates a centrifuge in a housing and holds and fixes the centrifuge by a fixing base. And the rotor of a centrifuge is rotated by rotating a fixed base with a motor. Here, the rotary drive device is provided with a strip-shaped blood leak sensor disposed on the inner wall surface of the housing in order to detect blood leak from the centrifuge. For this reason, when blood leaks from the centrifuge, the leaked blood adheres to somewhere in the strip-shaped blood leak sensor by centrifugal force. Therefore, blood leak can be detected quickly even with a small amount of blood leak.

  In the rotation drive device for the centrifuge according to the present invention, the blood leak sensor is disposed at a height position of the rotation seal portion on the inner wall surface of the housing in a state where the centrifuge is disposed. It is desirable.

  This is because the blood leakage sensor from the centrifuge can be reliably detected by arranging the strip-shaped blood leakage sensor at such a position. When blood leaks from the centrifuge, it has been found that blood leaks from the component joint of the centrifuge, and in particular, there is a high possibility of leakage from the rotary seal portion. And when blood leaks from the rotation seal part of the centrifuge, it is blown off in the horizontal direction by centrifugal force and adheres to the inner peripheral surface of the housing. For this reason, the blood leakage sensor from the centrifuge can be reliably detected by disposing a band-shaped blood leakage sensor at the entire height of the inner peripheral surface of the housing at this height position.

  In addition, the rotary drive device for the centrifuge according to the present invention further includes an interface sensor disposed on the inner wall surface of the housing in order to detect the interface of the blood component centrifuged in the blood storage space. Preferably, the blood leak sensor is disposed on substantially the entire circumference of the inner wall surface of the housing excluding the interface sensor or the attachment portion of the interface sensor. This is because a small amount of blood leakage from the centrifuge can be detected more reliably by arranging the blood leakage sensor almost on the entire circumference of the inner wall surface of the housing.

  Further, in the rotation drive device of the centrifuge according to the present invention, the blood leak sensor is arranged in a state where the centrifuge is disposed, and the height position of the rotation seal portion on the inner wall surface of the housing, More preferably, it is provided at two locations with the height of the rotor bottom.

  This is because the blood leakage sensor from the centrifuge can be detected more reliably by arranging the strip-shaped blood leakage sensors at two positions in this way. This is because some centrifuges have a joint portion at the bottom of the rotor, and blood leakage may occur from this portion. In addition, when blood leaking from the rotary seal portion is not detected by the blood leak sensor provided at the height position of the rotary seal portion, the blood adhering to the inner peripheral surface of the housing hangs down due to gravity. The blood leakage sensor provided at the height position of the rotor bottom can be detected. From these facts, blood leakage can be detected with very high accuracy by providing blood leakage sensors at the two positions described above.

  Moreover, in the rotation drive device of the centrifuge according to the present invention, the lid body has a recessed portion formed on one of the contact surfaces so that the contact surfaces engage with each other in the closed state. It is desirable that a convex portion is formed on the other contact surface.

  By forming a convex part and a concave part on each of the contact surfaces of the half-divided lids so that the convex part and the concave part engage with each other with the half-divided lid body closed This is because it is possible to reliably prevent blood from leaking outside from the contact surfaces of the half-divided lids.

  Furthermore, in the rotary drive device for the centrifuge according to the present invention, it is desirable to provide an O-ring on the outer peripheral surface of the upper end of the housing so as to liquid-tightly seal the upper opening of the housing and the lid. .

  In this way, by providing the O-ring on the outer peripheral surface of the upper end of the housing, when the lid that is divided in half is closed, the outer edge of the lid and the outer peripheral surface of the housing are in close contact with each other via the O-ring. The upper opening and the lid can be sealed in a liquid-tight manner. Thereby, it is possible to reliably prevent blood from leaking from between the lid and the housing.

  According to the centrifugal drive device of the present invention, since the strip-shaped blood leak sensor is arranged on the entire inner peripheral surface of the housing, it is possible to accurately detect the blood leak from the centrifuge. it can. In particular, blood leakage sensors from the centrifuge can be prevented from leaking by providing blood leakage sensors at two positions, the height position of the rotary seal portion and the height position of the rotor bottom portion, in a state where the centrifuge is arranged. Can be detected with high accuracy.

  In addition, a convex portion and a concave portion are formed on each of the contact surfaces of the divided lids so that the convex portion and the concave portion can be engaged with each other with the half-divided lid closed, and the housing Since the O-ring is provided on the outer peripheral surface of the upper end, the contact surface between the lids and the gap between the lid and the housing can be reliably sealed when the half-divided lids are closed. Thereby, it is possible to reliably prevent blood from leaking from the rotary drive device.

  DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, a most preferred embodiment embodying a centrifugal drive device of the present invention will be described in detail with reference to the drawings. The rotational drive device according to the present embodiment is for rotationally driving a centrifuge provided in a blood component collection circuit.

  Therefore, a schematic configuration of the rotary drive device 10 will be described with reference to FIGS. FIG. 1 is a cross-sectional view of a rotary drive device. FIG. 2 is a top perspective view of the rotary drive device, showing a state where the lid is opened. FIG. 3 is a top perspective view of the rotary drive device, showing a state in which the lid is closed.

  The rotation drive device 10 includes a cylindrical housing 11 for housing the centrifuge 50, a fixed base 12 that fixes the centrifuge 50, a motor 13 that rotationally drives the fixed base 12, and an upper portion of the housing 11. And a lid 14 for opening and closing the upper opening of the housing 11. Further, on the inner peripheral surface of the housing 11, an interface sensor 15 for detecting the position of the interface of the blood component separated in the centrifuge 50 and blood for detecting blood leakage from the centrifuge 50. Leak sensors 16a and 16b are provided.

  The blood leak sensors 16a and 16b are belt-like sensors arranged almost all around the inner wall surface of the housing 11. The blood leak sensor 16a is configured by removing the attachment portion of the interface sensor 15 at the height position of the rotation seal portion 54 of the centrifuge 50 on the inner wall surface of the housing 11 with the centrifuge 50 disposed in the housing. The housing 11 is disposed over substantially the entire circumference of the inner wall surface. In addition, the blood leak sensor 16b is disposed over almost the entire circumference of the inner wall surface of the housing 11 at the height position of the bottom of the centrifuge 50 on the inner wall surface of the housing 11 in a state where the centrifuge 50 is disposed in the housing. ing.

  Here, the centrifuge 50 that is rotationally driven by the rotational drive device 10 will be briefly described. The centrifuge 50 is formed of a hard plastic such as polycarbonate. As shown in FIG. 1, the centrifuge 50 includes a rotor 51 having a blood storage space therein, an inlet 52 communicating with the blood storage space provided in the rotor 51, and a flow. A stator 55 having an outlet 53 and a rotary seal portion 54 that seals the rotor 51 and the stator 55 in a liquid-tight manner are provided. Then, blood is introduced into the rotor 51 from the inflow port 52, and the blood is centrifuged into a plurality of blood components by rotating the rotor 51, and a specific blood component is discharged from the outflow port 53. . The rotor 51 includes a bell-shaped main body 51a and a disk-shaped bottom 51b, and is a container formed by joining the main body 51a and the bottom 51b by ultrasonic welding or the like.

  The rotation drive device 10 is configured to house the above-described centrifuge 50 in the housing 11 and rotate it. The fixed base 12 provided in the rotary drive device 10 has the same top surface as the bottom 51b of the rotor 51 of the centrifuge 50, and is held and fixed while keeping the centrifuge 50 in a horizontal state. Specifically, the centrifugal separator 50 is placed on the fixing base 12 and held and fixed by vacuum suction (vacuum chuck method). The fixed base 12 is connected to a motor 13 and is rotated by driving the motor 13. At this time, the centrifuge 50 is supported by the lid 14 at a portion between the rotary seal portion 54 and the inlet 52 and outlet 53.

  The lid 14 is composed of half-divided lids 14a and 14b. The lids 14a and 14b are pivotally supported by a hinge portion 17 provided on a flange 11a formed above the housing 11, as shown in FIGS. Accordingly, the lids 14a and 14b are rotated along the upper surface of the flange 11a to perform an opening / closing operation.

  As shown in FIG. 2 and FIG. 4, convex portions 19 and concave portions 20 are formed on the contact surfaces 18 a and 18 b of the lids 14 a and 14 b, respectively. That is, the convex portion 19 is formed on the contact surface 18a of the lid 14a, and the concave portion 20 is formed on the contact surface 18b of the lid 14b. FIG. 4 is a cross-sectional view of the vicinity of the lid, showing a state where the lid is open. These convex portions 19 and concave portions 20 engage with each other as shown in FIG. 5 when the lid 14 (14a, 14) is closed. As a result, when the lid 14 (14a, 14b) is closed, it is possible to reliably prevent blood from leaking from the contact surfaces of the lids 14a, 14b.

  An O-ring 21 is disposed on the outer peripheral surface of the upper end of the housing 11 (the part protruding from the flange 11). When the lid 14 (14a, 14b) is closed, the O-ring 21 is crushed by the outer edge portions 22a, 22b of the lids 14a, 14b as shown in FIG. In other words, the lids 14 a and 14 b and the housing 11 are brought into close contact via the O-ring 21. Thus, when the lid 14 (14a, 14b) is closed, the space between the lid 14a, 14b and the housing 11 is sealed by the O-ring 21, so that it is possible to reliably prevent blood from leaking from this portion. It is like that.

  As described above, in the rotation drive device 10, by providing the above-described configuration of the lid portion, even if blood leaks from the centrifuge 50, the leaked blood is not leaked to the outside. ing.

  Next, the operation of the rotary drive device 10 having the above configuration will be described. First, as shown in FIG. 2, the lid 14 (14 a, 14 b) is opened, and the centrifuge 50 attached to the blood component collection circuit (not shown) is accommodated in the flange 11. At this time, the bottom 51 b of the rotor 51 in the centrifuge 50 is placed on the fixed base 12. Then, the centrifugal separator 50 is sucked and held and fixed on the fixing table 12. When the fixing of the centrifuge 50 onto the fixing base 12 is completed, the lid 14 (14a, 14b) is closed as shown in FIG. As a result, the centrifuge 50 is supported by the lid 14 at a portion between the rotary seal portion 54 and the inlet 52 and outlet 53. Thus, the mounting of the centrifuge 50 to the rotary drive device 10 is completed.

  Further, when the lid 14 (14a, 14b) is closed, the convex portion 19 and the concave portion 20 formed on the lid 14a, 14b are engaged. Further, the space between the lids 14 a and 14 b and the housing 11 is sealed by the O-ring 21.

  When the mounting of the centrifuge 50 on the rotary drive device 10 is completed, the motor 13 of the rotary drive device 10 is driven. By driving the motor 13, the centrifuge 50 (more precisely, the rotor 51) fixed on the turntable 12 is rotated together with the turntable 12. Thereby, the blood introduced into the rotor 51 is centrifuged into a plurality of blood components, and specific blood components are discharged from the centrifuge 50.

  Here, if blood leaks from the centrifuge 50 during the centrifugation of the blood, the leaked blood adheres to the inner peripheral surface of the housing 11 by centrifugal force. When blood leaks from the centrifuge 50, it has been found that blood leaks from the component joint portion of the centrifuge 50, and in particular, there is a high possibility of leakage from the rotary seal portion 54.

  In the rotation driving device 10, the blood sensor 16a is disposed at the height position of the rotary seal portion 54. Therefore, when blood leaks from the rotary seal portion 54, the leaked blood adheres to the blood leak sensor 16a. To do. At this time, even if the blood leakage from the rotary seal portion 54 is very small, the blood leakage sensor 16a is disposed on the entire inner peripheral surface of the housing 11, and thus can reliably detect blood leakage.

  When the blood leaking from the rotary seal portion 54 does not adhere to the blood leak sensor 16a, the blood adhering to the housing 11 hangs down. And in the rotational drive apparatus 10, the blood leak sensor 16b is also arrange | positioned also in the height position of the bottom part of the rotor 51. FIG. Thereby, when the blood leaking from the rotation seal part 54 is not detected by the blood leak sensor 16a, it is detected by the blood leak sensor 16b.

  As described above, the rotational drive device 10 is provided at two locations on the upper and lower sides of the housing 11, specifically, at two positions, that is, the height position of the rotary seal portion 54 and the height position of the bottom portion of the rotor 51. Therefore, the blood leak from the centrifuge 50 can be detected with high accuracy.

  When blood leakage from the centrifuge 50 is detected by the blood leakage sensor 16a or 16b, the driving of the motor 13 is stopped and the rotation of the rotor 51 is stopped. Thereafter, the lid 14 (14a, 14b) is opened, and processing such as cleaning the inside of the housing 11 and the centrifuge 50, and replacing the centrifuge 50 is performed.

  Here, there is a little time between the occurrence of blood leakage from the centrifuge 50 and the rotation of the centrifuge 50 being stopped. For this reason, blood leaking from the centrifuge 50 may scatter in the housing 11 and in the worst case, may leak to the outside of the apparatus. For this reason, in the rotary drive device 10, the convex portions 19 and the concave portions 20 are formed on the contact surfaces 18 a and 18 b of the lids 14 a and 14 b, respectively, and the lid 14 (14 a and 14) is closed. To engage. Further, when the O-ring 21 is disposed on the outer peripheral surface of the upper end of the housing 11 (the portion protruding from the flange 11) and the lids 14 (14a, 14b) are closed, the outer edges 22a, 22b of the lids 14a, 14b and the housing 11 Are in close contact with each other via an O-ring 21. Thus, in the rotary drive device 10, blood does not leak from the contact surfaces of the lids 14a and 14b and between the lids 14a and 14b and the housing 11 when the lid 14 (14a, 14b) is closed.

  As described above in detail, in the rotary drive device 10 according to the present embodiment, the strip-shaped blood leak sensors 16a and 16b are provided at two locations on the upper and lower sides of the inner peripheral surface of the housing 11; Can be detected with high accuracy. Moreover, since the convex part 19 and the recessed part 20 are each formed in the mutual contact surfaces 18a and 18b of the lid | cover 14a and 14b, and the O-ring 21 is arrange | positioned at the upper end outer peripheral surface of the housing 11, the lid | cover 14 ( 14a, 14b) is closed, blood does not leak from the contact surfaces of the lids 14a, 14b and between the lids 14a, 14b and the housing 11.

  It should be noted that the above-described embodiment is merely an example and does not limit the present invention in any way, and various improvements and modifications can be made without departing from the scope of the invention. For example, in the above-described embodiment, the vacuum chuck method is adopted as a method of fixing the centrifuge 50 to the fixing base 12, but a mechanical chuck method can also be adopted.

It is sectional drawing which shows schematic structure of the rotational drive apparatus which concerns on this Embodiment. It is a perspective view which shows the upper part (cover vicinity) of the rotational drive apparatus which concerns on this Embodiment, and shows the state which the cover opened. It is a perspective view which shows the upper part (cover vicinity) of the rotational drive apparatus which concerns on this Embodiment, and shows the state which the cover closed. It is sectional drawing which shows the cover vicinity of the rotational drive apparatus which concerns on this Embodiment, and shows the state which the cover opened. It is sectional drawing which shows the cover vicinity of the rotational drive apparatus which concerns on this Embodiment, and shows the state which the cover closed. It is sectional drawing which shows schematic structure of the conventional rotational drive apparatus. It is a perspective view which shows the upper part (cover vicinity) of the conventional rotary drive apparatus, and shows the state which the cover opened. It is a perspective view which shows the upper part (cover vicinity) of the conventional rotary drive apparatus, and shows the state which the cover closed.

Explanation of symbols

DESCRIPTION OF SYMBOLS 10 Rotation drive apparatus 11 Housing 12 Fixing base 13 Motor 14 (14a, 14b) Cover 16a, 16b Blood leak sensor 21 O-ring 50 Centrifugal separator 51 Rotor 52 Inlet 53 Outlet 54 Rotation seal part 55 Stator

Claims (6)

A centrifuge including a rotor having a blood storage space therein, a stator having an inlet and an outlet communicating with the blood storage space, and a rotary seal portion that seals the rotor and the stator in a liquid-tight manner is held. In the rotation drive device of the centrifuge to be rotated,
A cylindrical housing containing the centrifuge;
A half-divided lid for opening and closing the upper opening of the housing;
A disk-shaped fixing base for holding the centrifuge;
A motor for rotating the fixed base;
A centrifugal drive device for a centrifugal separator, comprising: a strip-shaped blood leakage sensor disposed on an inner wall surface of the housing for detecting blood leakage from the centrifugal separator. In the rotation drive device of the centrifuge according to claim 1,
The blood leakage sensor is disposed at a height position of the rotary seal portion on the inner wall surface of the housing in a state where the centrifugal separator is disposed. In the centrifuge rotation drive device according to claim 2,
Furthermore, in order to detect the interface of the blood component centrifuged in the blood storage space, it has an interface sensor disposed on the inner wall surface of the housing,
The blood leakage sensor is disposed at substantially the entire circumference of the inner wall surface of the housing excluding the interface sensor or the attachment portion of the interface sensor. In the rotation drive device of the centrifuge according to claim 1,
The blood leak sensor is provided at two locations, the height position of the rotary seal portion and the height position of the rotor bottom portion, on the inner wall surface of the housing in a state where the centrifuge is disposed. A rotary drive device for a centrifugal separator. In the rotational drive apparatus of any one centrifuge as described in Claim 1- Claim 4,
In the closed state, the lid has a concave portion formed on one contact surface and a convex portion formed on the other contact surface so that the contact surfaces engage with each other. A rotary drive device for a centrifuge characterized by that. In the rotation drive device of any one centrifuge according to claim 1 to claim 5,
Furthermore, an O-ring is provided on the outer peripheral surface of the upper end of the housing so as to liquid-tightly seal the upper opening of the housing and the lid body.

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