JP2005069728A - General-purpose living body relevant information recorded medium, its manufacturing method, its manufacturing device, detection device for general-purpose living body relevant information recorded medium, and medical system using these - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a system for manufacturing a biosensor easily with a printer or a personal computer for domestic use, and for performing detection. <P>SOLUTION: The biosensor is manufactured from an ink jet by an ink tank filled with a living body relevant material which is compatible with an ink jet printer. The sensor is constituted so that reading is performed by a CD drive for a general PC, and an inspection result is read by a personal computer and transmitted to a medical/inspection institution by Internet. The medical institution receives data by a communication wherein the security is secured, and transmits a diagnosis result. Ordering of the tank filled with the living body relevant material and a base material, and payment for a diagnosis fee or the like are performed by an internet protocol wherein the security is secured. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention manufactures, detects, and diagnoses biochips and biosensors in homes and offices using general-purpose commercially available devices such as inkjet printers and CD drives built in personal computers, and provides diagnostic information via the Internet to medical institutions, etc. The present invention relates to a general-purpose biological related information recorded medium such as a biochip and a biosensor to be transmitted to the device, a manufacturing method thereof, a manufacturing apparatus, a general-purpose biological related information recorded medium detection device, and a medical system using these.
[0002]
[Prior art]
In recent years, Affymetrix-type and Stanford-type DNA chips are known as a typical form of biochip. These have been put to practical use by various companies. For example, in the DNA chip of Agilent Technologies, more than tens of thousands of DNAs are spotted by a special inkjet printing technique and immobilized in double strands by hybridization with the DNA of the specimen. This is detected by a dedicated scanner by fluorescence emission of DNA that has been fluorescently labeled and spotted in advance. (See FIG. 4 and Non-Patent Document 1)
In Patent Document 1, an individual can use a portable health care information terminal to regularly view health information such as body temperature, blood pressure, medication, etc. on a regular basis, at an abnormal time, and at any time, A business model is created by systematizing a means for an individual to register data in his / her medical insurance information database in a medical facility via the Internet and enabling the individual to browse his / her registered information.
[0003]
However, in such a model, a new medical portable terminal must be prepared, and in addition to simple medical information such as body temperature and blood pressure, DNA-related diagnosis and biochips that have made remarkable progress in recent years In advanced diagnosis, it is necessary to go to a medical institution or inspection institution, and it is still a burden on patients suffering from some kind of disease and the elderly.
[0004]
In addition, Patent Document 2 discloses human genome information such as genetic polymorphisms and mutations of unspecified masses and treatment methods, drug compatibility, constitution analysis, disease prevention, etc. via the Internet, dedicated lines, mail, courier services, etc. A technique for facilitating the above is disclosed. This prior example is a business model that is useful for preventing various unspecified diseases by publishing associations between genetic information corresponding to diseases and the like and transmitting actual genetic information and samples.
[0005]
In the above-mentioned prior patent application, genetic information is shared, but it is impossible to diagnose individual-based disease transitions in time series such as so-called trend tests at home. Moreover, regarding individual information, there is little continuity, and there is a possibility that a business cannot be established unless a large number is targeted.
[0006]
[Patent Document 1] Japanese Patent Laid-Open No. 2002-183316
[Patent Document 2] Japanese Patent Application Laid-Open No. 2001-292600
[Non-Patent Document 1]
http: // www. chem. Agilent. com / cag / country / JP / products / PDS2433. htm
[0007]
[Problems to be solved by the invention]
However, the conventional DNA chip has a merit that it has a high density and increases analysis result information, but it is very expensive at several hundreds of thousands of yen for a single slide glass. A special scanner and PC as shown in Fig. 1 are required.
[0008]
Therefore, even if it is a general practitioner or a small hospital as well as a general household, it can be used to detect bio-related substances such as genetic diagnosis using DNA chips, blood tests, various antibody tests, O157 Detection, detection of influenza virus, etc. are virtually impossible, resulting in the inconvenience and high price of these tests and a significant delay in receiving the test results.
[0009]
In addition, continuous trend diagnosis is not required for gene information collection using a DNA chip. On the other hand, in the secular change of blood state, antigen antibody test, and virus detection, trend data management and judgment / diagnosis from normal times are necessary in the sense of onset prediction and preventive diagnosis. However, the conventional inspection form using such a biochip has many problems for its widespread use because it requires access to a large amount of facilities and medical institutions as described above.
[0010]
The present invention has been made in view of the circumstances as described above, and its purpose is general-purpose such as biochips and biosensors that are excellent in cost and can perform simple diagnosis, preventive diagnosis, and symptom trend diagnosis in general homes. It is an object of the present invention to provide a living body related information recorded medium, a manufacturing method thereof, a manufacturing apparatus, a detecting apparatus, and a medical system using them.
[0011]
[Means for Solving the Problems]
The inventors of the present application have made extensive studies in order to achieve the above object. As a result, we focused on the fact that existing printers and personal computers that are widely used in general households have become finer and more functional, and using this, we made simple biochips and biosensors, detected them, Similarly, the present inventors have found that the above object can be achieved by transmitting to a desired medical institution via the Internet, which has been spreading widely. That is, in recent years, a commercially available printer that has become capable of high-precision, small-volume ejection and has been widely used in general households is used as a DNA spotter to produce DNA chips, biochips, and biosensors, which are also built into personal computers. The above objective can be achieved by reading and analyzing the reaction of the sample on a biochip or biosensor manufactured by a CD drive with existing or simple additional parts, and transmitting it to a medical institution via a communication network such as the Internet. The headline and the present invention were completed.
[0012]
In order to solve the above-described problem, the general-purpose bio-related information recorded medium of claim 1 is characterized in that it is immobilized on a general-purpose personal computer storage medium in a readable state.
[0013]
According to a second aspect of the present invention, there is provided a general-purpose biological-related-information-recorded medium that is a biochip or a biosensor in order to solve the above problems.
[0014]
According to the above configuration, since an existing general-purpose personal computer storage medium is used as a base material, a bio-related substance can be used as a general-purpose personal computer and peripheral devices so that a CD label can be printed with a print adapter. By applying or dropping onto a personal computer storage medium, it is possible to obtain a storage medium in which living body related information is stored easily and compactly.
[0015]
In order to solve the above-described problems, the general-purpose biological-related information recorded medium of claim 3 is a particle sensor in which particles are immobilized as a biological-related substance.
[0016]
According to said structure, the quantity of allergen etc. can be detected more simply by immobilizing pollen, house dust, and other biological related particles as biological related substances.
[0017]
According to a fourth aspect of the present invention, there is provided a method for producing a general-purpose biomedical information recorded medium. In order to solve the above-mentioned problem, the biometric substance is printed on a general-purpose personal computer storage medium by printing means. It is characterized by immobilizing a biological substance on a medium in a readable state.
[0018]
An apparatus for producing a general-purpose bio-related information recording medium according to claim 5 is an inkjet printer that discharges a bio-related substance in an ink tank to a general-purpose personal computer storage medium via an inkjet nozzle in order to solve the above-described problem; It is characterized by comprising an ink tank that can be connected to an ink jet printer and filled with a biological substance, and a holder that supports the storage medium for a general-purpose personal computer with respect to the ink jet printer.
[0019]
According to said structure, a biological material can be apply | coated or dripped easily to the storage medium for general purpose personal computers using a commercially available inkjet printer. For this reason, it is possible to obtain a general-purpose biological information-recorded medium such as a biochip and a biosensor that is excellent in cost and can perform simple diagnosis, preventive diagnosis, and symptom trend diagnosis in general homes. In addition, since the production apparatus itself includes the above-described ink jet printer, it is possible to conveniently apply or drop the biological substance on a general-purpose personal computer storage medium.
[0020]
In order to solve the above-described problem, the manufacturing apparatus according to claim 6 includes a biological substance introduction means for dripping or applying a biological substance to a storage medium for a general-purpose personal computer or introducing it from an external dripping device, And a lid for preventing scattering of the applied biological substance.
[0021]
According to said structure, a production apparatus is provided with the said biological body related substance introduction means, Therefore The function of the existing inkjet printer can be utilized more smoothly for manufacture of the general purpose biological body related information recorded medium. Moreover, by having the said cover body, contamination of the apparatus system | strain by a biological material can be prevented beforehand.
[0022]
In order to solve said subject, the detection apparatus for general purpose bio-related information recorded media of Claim 7 WHEREIN: The bio-related material on the general-purpose bio-related information recorded medium of any one of Claims 1-3. A general-purpose personal computer drive for inserting the above-mentioned general-purpose biological-related information recorded medium that has reacted with the specimen, an excitation light source for exciting the fluorescent substance of the reacted specimen on the general-purpose biological-related information recorded medium, An emission wavelength reading unit and an output unit for outputting a fluorescence detection signal are provided.
[0023]
According to the above configuration, the general-purpose bio-related information-recorded medium of the present invention is inserted into a general-purpose personal computer drive, and information such as fluorescent labels and fluorescent-labeled antibodies immobilized on the medium is stored in existing personal computers and peripheral devices. This function can be used for simpler detection. For this reason, bio-related information on general-purpose bio-related information recorded media such as biochips and biosensors that are cost-effective and can be used for simple diagnosis, preventive diagnosis, and symptom trend diagnosis in general homes is more efficient in medical institutions. Can be used.
[0024]
In order to solve the above-described problem, the detection device according to claim 8 uses an optical system in which a drive for a general-purpose personal computer performs excitation and reading of a fluorescent pattern, and optical storage and readout used for a storage medium for general-purpose personal computers. It is characterized by comprising an optical servo system to perform.
[0025]
According to the above configuration, an existing general-purpose personal computer drive such as a CD drive can excite and read a fluorescent pattern using the same optical system as an optical recording and reading optical system such as an existing CD, CDR, CDRW, or DVD. Since an optical servo system is provided, there is no need to newly install another optical system or servo system.
[0026]
In order to solve the above-described problem, the detection device according to claim 9 prints and fixes biological-related information included in the specimen in a readable state on a storage medium for general-purpose personal computers. A general-purpose bio-related information recorded medium manufacturing apparatus having a first control unit for controlling the output of the output unit, and the bio-related information included in the general-purpose bio-related information recorded medium inserted in a general-purpose personal computer drive A second output unit that detects a signal, a calculation unit that processes a signal from the second output unit, a second control unit that analyzes a biological related information of a specimen from a calculation result in the calculation unit, and the second 2 A medical system comprising a general-purpose biological related information recorded medium detection device having a communication control unit that transmits a diagnosis result made by the control unit to a medical institution or a testing institution via Internet communication. The detection apparatus includes a receiving unit for receiving information related to the biological related information such as information related to other biological related substances, examination methods, and handling instructions via Internet communication, and the communication control unit includes the reception The information obtained from the department is analyzed, and the electronic transaction of the examination fee is controlled together with the reception of the examination result from the medical institution or the examination institution.
[0027]
According to the above-described configuration, general-purpose bio-related information recorded media such as biochips and biosensors that are excellent in cost and can be used for simple diagnosis, preventive diagnosis, and symptom trend diagnosis in general households, and production devices and detection thereof. Devices and medical systems using these devices can be provided.
[0028]
In other words, with the above medical system, home inspection with medical institutions / laboratories can be performed without time lag, trend data can be managed, and diagnostic costs can be withdrawn from a pre-registered account or credit card via the Internet. Can be established safely with the latest technology.
[0029]
It is self-evident that the “diagnosis result” in the control unit of the general-purpose personal computer and the “diagnosis” by the doctor in the medical institution based on the diagnosis have different medical meanings.
[0030]
DETAILED DESCRIPTION OF THE INVENTION
An embodiment of the present invention will be described below with reference to the drawings.
[0031]
The general-purpose bio-related information-recorded medium according to the present embodiment is in a state in which a bio-related substance can be read on a general-purpose personal computer storage medium capable of optical recording and reading such as CD, CDR, CDRW, and DVD. It is fixed.
[0032]
The general-purpose living body related information recording medium production apparatus according to the present embodiment has a configuration in which a commercially available inkjet printer installed in a general home or office is built in or externally attached as necessary.
[0033]
Including a personal computer (general-purpose personal computer, PC) including a CD drive or a digital camera, and an ink tank compatible with the above-described commercially available inkjet printer filled with a biological material, a base material for manufacturing a biochip, a modem, and the like Internet connected to PC via PC, similarly database of medical / inspection institution connected to Internet, medical institution and printer, account or credit registered by individual or corporation who owns PC and contracts with medical / inspection institution Includes billing information such as cards.
[0034]
FIG. 2 is an explanatory view showing the ink jet printer 17 provided in the production apparatus for a general-purpose biological related information recorded medium according to the present embodiment. In FIG. 2, the print adapter 8 (holder) indicates an adapter that performs label printing of the print CD 19. As shown in FIG. 2, the ink jet printer 17 is a bio-related device from an ink tank through an ink jet nozzle mounted on the ink jet printer by placing the print adapter 8 on a paper feed tray 18 of a commercially available ink jet printer. The material is printed on CD 19 and immobilized.
[0035]
FIG. 3 is an explanatory diagram showing ink tanks 20a, 20b, and 20c of a commercially available printer that is preferably used as the ink tank of the manufacturing apparatus of the present embodiment. The ink tanks 20a, 20b, and 20c may store specimens, fluorescently labeled antibodies, and other types of biological materials as necessary, and may be filled with the same type of biological materials. . Further, an adhesive / adsorbent for fixing particles such as pollen may be filled.
[0036]
FIG. 7 is a bottom view of the ink jet printer nozzle portion 24 used in the manufacturing apparatus of the present embodiment. The nozzle arrangement shown in FIG. 7 is an example, and there are 180 nozzles per inch.
[0037]
The nozzle arrangement is 0.14 mm in terms of pitch, but by arranging these nozzles in a staggered pattern or by devising the head position, for example, 1/2880 as shown in FIG. It is possible to print dots at a pitch of inches (= 8.8 μm).
[0038]
Further, by controlling the amount of droplets, it is possible to generate fine dots as shown in FIG. This is fine enough to satisfy a function as a biochip or DNA chip, and is sufficient for producing a relatively simple biosensor and biochip targeted at home.
FIGS. 10 to 16 show an embodiment from the application of a biological substance to a CD-like biological substance base material by inkjet, printing and reading.
[0039]
FIG. 10 shows a recording bit configuration of a general CD, CDR, DVD or the like. Here, taking a CD as an example, a so-called bit is recorded along the recording line 28. Normally, music CDs and the like are mass-produced by an injection molding machine using a mold, and are usually composed of 16 bits each consisting of 0 bits in a 29a circle and 1 bit in an ellipse 29b. These bits = pits are serial recording in which the left and right signals are written in series, and are continuously written in a spiral shape from the outer peripheral portion toward the inner peripheral portion. Here, the synchronization signal and the error correction bit are omitted. In short, these bits are used as a pit following servo signal of the optical system.
[0040]
FIG. 11 shows data recording for one sampling represented by only 0 bits. For example, 16 bits 30 of the left channel and 16 bits of the right channel are serially read along the time axis 32.
FIG. 12 is a pit trace locus viewed from the recording surface side of a CD = recording line 28, and FIG. 13 is a schematic diagram showing a state where a biomaterial is applied by inkjet. As shown in the figure, the bio-related substance is fixed to a predetermined position of the left channel signal (16 bits) 30 with a certain area determined in consideration of convenience at the time of reading. That is, even if it does not necessarily coincide with the position of the pits, since the pits of the CD are enormous, any of the bio-related substances is discharged onto the pits, and it is allowed even if the whole does not overlap with the pits.
FIG. 14 shows a state in which the biomaterial is accurately applied on the pit. In the pit trace of a CD, the servo operates so as to follow the pit signal while picking up the pit signal, so that only one or two pits are not blocked too much as shown in FIG. Trace must work.
[0041]
As described above, in the present invention, the biological material 33 is applied by ink jetting to a specific position on the recording line 28 based on information unique to the biological material. More specifically, as shown in FIG. 14, the biological material 33 applied by inkjet is fixed to a plurality of points on the recording line 28 based on the type or the like unique to the material. At this time, if the range is determined to some extent and the biological material 33 is fixed around the pit row at the beginning of the reading line, that is, near the center, for example, a plurality of bits are fixed to at least one bit on the recording line 28 Therefore, it can be read by a normal reading operation.
[0042]
FIG. 15 schematically illustrates a reading mechanism such as a general CD or CDR. The CD 27 is set substantially at the center by an axis centering mechanism having a taper of 36, and is fixed by a pressing mechanism 35. The CD is rotated from the lower motor in this case, and when the biomaterial has a fluorescent marker, the CD is irradiated from the lower surface by an excitation lamp or LED 37 of a fluorescent light emitter. Even if 37 is not in such a close form, if the CD surface can be irradiated, the entire surface may be irradiated from an appropriate place on the lower surface of the CD drive. The normal bit reading mechanism reads the pit by performing pit servo, race (horizontal arrow), and vertical focusing. In the case of this patent system, if the signal to be read is designed to be larger than the normal 0 pit, for example, due to the emission intensity, the fluorescence signal of the biomaterial can always be read at a level of 1. In FIG. 14, the biomaterial is illustrated as being applied in a circular shape, but it may be an oval shape. Further, it may be 2 to 3 times as long as a normal 1-bit pit.
[0043]
The application of biomaterials is not necessarily performed with one type, and therefore, there are many cases in which a plurality of biomaterials are applied. However, in the conventional biochip, a specific biomaterial, for example, DNA is often dropped on the designated coordinates. However, in this patent, since diagnosis is performed using a home printer or a personal computer, it is difficult to apply and measure many kinds of biomaterials. Therefore, as shown in FIG. 16, a certain area such as 44a to 44c is provided, and the same biomaterial is placed in a plurality of regions at a density capable of being traced so as to overlap as much as possible inside the pit. By applying, it becomes easy to detect a plurality of biomaterials. It is a CD that is a rotating body, and it is difficult to define the position of a pit like an XY coordinate on a spiral trajectory, and if it is a fan-shaped block area containing a plurality of concentric trajectories, The identification of the area is based on the idea that it is relatively easy. Of course, the area block may not be large as shown in FIG.
[0044]
On the other hand, as described above, FIGS. 4 to 6 are examples of DNA chip inspection apparatuses that have been conventionally considered to be the finest, and are called scanners. As shown in each figure, the conventional scanner is large in shape, requires a dedicated PC, and further requires a DNA analysis information database.
[0045]
The biological material (biomaterial) according to the present invention refers to, for example, DNA or protein, and includes, for example, antibodies and sugar chains. In addition, the biological material according to the present invention includes particles such as pollen and house dust, and other particles that are allergens. However, it is clear that the size of the particles must be on the order of similarity to the spacing and size of the CD pits.
[0046]
Examples of the general-purpose biological-related information-recorded medium of the present invention include a biochip, a DNA chip, and a biosensor.
[0047]
As a biosensor manufacturing method according to the present invention, for example, a substrate processed into a CD shape is preliminarily disposed of a biological substance using an inkjet printer with a print adapter as described above for printing a CD label. For example, printing may be performed in this place. The base material may be subjected to a surface treatment with good adhesion of a biological substance or a treatment such as water repellency at a portion where it is not desired to adhere.
[0048]
As a specific method for detecting biological information using the detection device for general-purpose biological information recorded medium of the present invention, a fluorescently labeled antibody that can be read by an optical system with a built-in CD drive, etc. The method using is mentioned.
[0049]
Alternatively, a method or the like in which the biological substance is modified in advance so that the pit length direction can be determined as 0 or 1 by a predetermined reaction may be used.
[0050]
The CD-type biosensor manufactured in the above-described process reads a sample with a sample dropped and optical color development or a variable pit length with a CD drive. It is arranged to be compatible with normal CD pit reading, whereby the inspection result is read with a digital signal and stored in the memory of the PC. A contractor with a medical institution can transfer this data from the Internet to a medical examination institution through a secure communication means and store it in an individual database. Using a digital camera is a simpler method. For example, in the case of a bio-related substance that emits fluorescence, a simple black light (not shown) is illuminated, the fluorescence emission is photographed, and the pattern is transmitted to a medical institution. Will do.
[0051]
Next, the medical system according to the present embodiment will be described below.
FIG. 1 is an explanatory diagram showing the overall configuration of the medical system of the present embodiment.
Block 1 indicates that the equipment is present in a general home or office. In this medical system, a home (office) printer 7, a digital camera 13, and a PC 6 are the basic components. In this block 1, the biochip base material 9 and the bio-related substance-filled ink tank 10 are purchased and set in the print adapter 8 in a CD 19 form. For example, the home printer 7 can be downloaded from the Internet or biochip The bio-related material is printed and applied to the biochip substrate 9 in an ink-jet manner by the biosensor drawing software attached to the creation set to create a biochip 12 (general-purpose bio-related information recorded medium).
[0052]
The specimen 11 of the subject is dropped on the biochip 12 thus produced and reacts with the biological substance. The reacted biological substance emits light when, for example, laser excitation is performed. Therefore, a CD is inserted into the PC CD drive, and data of the light emitting unit is collected through the existing reading optical system 16. Alternatively, a partially dedicated reading optical system 15 may be attached for excitation of light emission. On the other hand, the light emission state of the CD may be read off-line by the digital camera 13.
The read data is transmitted from the personal computer 6 connected to the Internet communication network 5 to the medical institution / inspection organization 4 via the Internet network. The medical examination 4 has its own bioanalysis information (bioinformatics) 3 or similarly downloads it from the Internet network and analyzes the data contents.
[0053]
In addition, the medical institution notifies the above-mentioned diagnosis analysis result to an individual in one home or office or gives an instruction for home treatment through the Internet network. As a compensation, the medical institution can obtain diagnosis costs, biochip base material 9, bio-related substance-filled ink tank 10 from the bank account or credit card of representative / user of household 1 registered in advance on the Internet 5 or offline. Deduct expenses such as, and they will be notified on the bank or credit company statement.
[0054]
As described above, in the medical system of the present invention, attention is paid to the fact that existing printers and personal computers that are widely used in general households are miniaturized and highly functionalized, and simple biochips and biosensors are utilized by using this. Is detected, and transmitted to the desired medical institution via the Internet, which is also becoming popular. Thereby, it is excellent in cost property, and simple diagnosis, preventive diagnosis, and data trend diagnosis in a general home can be performed. In addition, with this medical system, in-house inspections with medical institutions / inspection institutions can be performed without time lag, data management can be performed, and diagnosis / inspection costs can be safely and securely stored from registered accounts and credit cards via the Internet. Be debited.
[0055]
【The invention's effect】
General-purpose living body related information recorded medium such as biochip and biosensor of the present invention, and manufacturing method, manufacturing apparatus, detection apparatus thereof, and integration thereof, and communication between home inspection and medical institution diagnosis / judgment / monitor As described above, the medical system integrated in the system, as described above, manufactures and inspects biosensors, etc. according to the purpose in the home or office using existing printers and personal computers, and transfers them to specialized medical / inspection institutions via the Internet. The results are collected and the charges are collected via the Internet, so it is possible to measure the trend continuously without going to a medical institution for testing using advanced biosensors. With this, it is possible to provide advanced medical diagnosis / testing.
[Brief description of the drawings]
FIG. 1 is an explanatory diagram showing an embodiment of a biobusiness model.
FIG. 2 is an explanatory diagram showing an ink jet printer 17 provided in the general-purpose bio-related information recorded medium manufacturing apparatus according to the present embodiment.
FIG. 3 is an explanatory diagram showing ink tanks 20a, 20b, and 20c of a commercially available printer that is preferably used as an ink tank of the manufacturing apparatus of the present embodiment.
FIG. 4 is a conventionally used DNA chip scanner.
FIG. 5 is an explanatory diagram showing a schematic structure of the scanner.
FIG. 6 is an explanatory diagram showing a schematic structure of the scanner.
FIG. 7 is an explanatory diagram showing a nozzle configuration of a commercially available inkjet printer.
FIG. 8 is a dot image by a commercially available inkjet printer.
FIG. 9 is a droplet dot image of a commercially available inkjet printer.
FIG. 10 is a conceptual diagram of a general CD recording signal.
FIG. 11 is an explanatory diagram showing a CD recording signal (represented only by 0 bits);
FIG. 12 is a conceptual diagram (viewed from the recording surface) of a CD pit trace.
FIG. 13 is a schematic diagram of inkjet coating of a biological substance.
FIG. 14 is an explanatory diagram showing an application state (viewed from the recording surface) of a biological substance on the entire CD.
FIG. 15 is an explanatory diagram showing a CD reading mechanism.
FIG. 16 is an explanatory diagram showing a bio-related substance application pattern.
[Explanation of symbols]
1 Home and office areas
2 trading window
3 Bio-related analysis / diagnosis information
4 Medical institutions and inspection institutions
5 Internet
6 Home and office PC
7 Household (and office inkjet) printers (printing means)
8 Print adapter (holder)
9 Biochip substrate
10 Ink tank filled with bio-related substances
11 specimens
12 Biochip
13 Digital camera
14 CD drive for PC
15 Dedicated reading optical system
16 Existing reading optical system
17 Inkjet printer body
18 Paper tray
19 CD
20a Ink tank
20b Ink tank
20c ink tank
21 Dedicated scanner lid for DNA chip
22 Dedicated scanner body for DNA chip
23 PC for exclusive use of DNA chip scanner
24 Inkjet printer nozzle (bottom)
25 Inkjet nozzle configuration
26 Center hole
27 CD
28 recording lines
29 Enlarged view of recording bits
29a Small bit (0)
29b Large bit (1)
30 Left channel signal (16 bits)
31 Right channel signal (16 bits)
32 Reading time axis
33 Inkjet-coated biomaterials
34 Spindle shaft
35 Pressing mechanism
36 Lower rotation axis alignment mechanism
37 Excitation lamp or LED
38, 40 Servo mechanism fixing mechanism
39 Servo mechanism (for horizontal axis drive)
41 Reading optical system and built-in focusing mechanism
42 Excitation lamp fixing mechanism
43 Normal pit reading optical system tip
44a to 44c Application area of specific biological substance

Claims (9)

A general-purpose bio-related information recorded medium, wherein a bio-related substance is immobilized in a readable state on a general-purpose personal computer storage medium. 2. The general-purpose biological related information recorded medium according to claim 1, wherein the medium is a biochip or a biosensor. 3. The general-purpose biological information-recording medium according to claim 1, wherein the general-purpose biological information-recording medium is a particle sensor in which particles are immobilized as a biological material. General-purpose bio-related information recording characterized in that the bio-related substance is readable on the general-purpose personal computer storage medium by printing the bio-related substance on the general-purpose personal computer storage medium by the printing means. Manufacturing method of finished media. An inkjet printer that discharges bio-related substances in the ink tank to a general-purpose personal computer storage medium via an inkjet nozzle;
An ink tank that can be connected to an ink jet printer and is filled with a biological material;
A holder for supporting the general-purpose personal computer storage medium with respect to the inkjet printer;
The apparatus for producing a general-purpose biological-related information recorded medium according to any one of claims 1 to 4, further comprising: A bio-related substance introduction means for introducing or applying a bio-related substance to a storage medium for general-purpose personal computers from an external dripping device;
A lid for preventing splashing of the bio-related substance dropped or applied;
The manufacturing apparatus according to claim 3, further comprising: A drive for a general-purpose personal computer for inserting the general-purpose biological-related information recorded medium obtained by reacting the biological-related material on the general-purpose biological-related information recorded medium according to any one of claims 1 to 3 with a specimen;
An excitation light source for exciting the fluorescent substance of the reacted specimen on the general-purpose biological-related information recorded medium;
Reading means of fluorescence emission wavelength;
An output means for outputting a fluorescence detection signal;
A general-purpose living body-related information recording medium detecting device comprising: 8. The general-purpose personal computer drive is provided with an optical servo system that performs excitation and reading of a fluorescent pattern using an optical system that performs optical storage and readout used in a general-purpose personal computer storage medium. General-purpose living body-related information recording medium detection device. A first output unit that prints and immobilizes biological related information of the specimen in a readable state on a storage medium for general-purpose personal computers;
A first control unit for controlling the output of the first output unit;
An apparatus for producing a general-purpose bio-related information recorded medium comprising:
A second output unit for detecting a signal corresponding to the bio-related information of the general-purpose bio-related information recorded medium inserted in the drive for a general-purpose personal computer;
An arithmetic unit for processing a signal from the second output unit;
A second control unit that performs diagnosis by analyzing biological-related information of the specimen from the calculation result in the calculation unit;
A communication control unit for transmitting a diagnosis result made by the second control unit to a medical institution or a testing institution via Internet communication;
A medical system comprising a general-purpose biological-related information recorded medium detection device comprising:
The detection apparatus includes a receiving unit for receiving information related to the biological related information such as information related to other biological related substances, examination methods, and handling instructions via Internet communication,
The said communication control part analyzes the information obtained from the said receiving part, and controls the electronic transaction of a consultation fee with reception of the test result from the said medical institution or a test | inspection organization, The medical system characterized by the above-mentioned.

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