JP2003275303A - Syringe pump and method for sending fluid - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a syringe pump which sends medical fluid to a patient on the basis of a determined fluid sending (injecting) pattern and generates alarm when a detected occlusion pressure becomes less than a set lower limit value of occlusion pressure. <P>SOLUTION: The syringe pump for sending the medical fluid within a syringe according to the injecting pattern determined in advance comprises; a fluid sending pattern input means for inputting the fluid sending pattern; an occlusion pressure setting means for setting the lower limit value of occlusion pressure; and a driving control means for drive-controlling a motor on the basis of the inputted fluid sending pattern and pressurizing the presser of the syringe for injecting the medical fluid within the syringe. Then, the syringe pump detects reduction in the detected occlusion pressure to the set lower limit value of occlusion pressure or below, and stops driving of the motor a prescribed time after alarm generation on the basis of the inputted liquid fluid pattern. <P>COPYRIGHT: (C)2003,JPO

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention
The present invention relates to a syringe pump that delivers a drug solution to a patient based on an (injection) pattern, and generates an alarm when the set lower limit value of the occlusion pressure is exceeded.

[0002]

2. Description of the Related Art Syringe pumps have been proposed in which the occlusion pressure detection level (upper limit value or upper limit value and lower limit value) is selected in advance from a plurality of regions and a medicinal solution is injected based on a set constant infusion rate ( For example, Japanese Patent No. 2785114). Detects the blockage of the infusion line and sets the upper limit value of the blockage pressure to generate an alarm. Also detects the disconnection of the infusion line and sets the lower limit value of the blockage pressure to generate the alarm. . However, there is a problem that when the blockage detection pressure falls below the lower limit value for some reason, an alarm is immediately generated and the driving of the motor is stopped.

[0003]

Therefore, in view of the above circumstances, the present invention does not stop the motor drive immediately even when the detected closing pressure falls and stops the motor drive after a predetermined time (predetermined seconds / predetermined minutes). An object of the present invention is to provide a syringe pump capable of operating.

[0004]

In order to achieve the above object, a syringe pump of the present invention is a syringe pump for delivering a drug solution in a syringe in accordance with a predetermined injection pattern, and inputs a solution delivery pattern. A liquid delivery pattern input means, a closing pressure setting means for setting a closing pressure lower limit value,
It consists of drive control means that drives and controls the motor based on the input liquid transfer pattern and presses the pusher of the syringe to inject the drug solution in the syringe, and detects that the set closing pressure is below the lower limit value. Then, the driving of the motor is stopped at a predetermined time after the alarm is generated based on the inputted liquid feeding pattern. Further, it is characterized by further comprising a syringe diameter detecting means for detecting the capacity of the syringe. Further, it is characterized by further comprising setting means for setting the manufacturer name of the syringe. Further, it is characterized by further comprising means for inputting and / or selecting a drug name.

The method for delivering a syringe pump according to the present invention is a method for delivering a drug solution in a syringe in accordance with a predetermined injection pattern, which comprises a step of inputting a delivery pattern and a closing pressure. The step of setting the lower limit value, the drive control of the motor based on the input liquid transfer pattern, the step of pressing the pusher of the syringe to inject the drug solution in the syringe, and the lower limit value of the set occlusion pressure are set. A step of detecting that the temperature is lower than the predetermined value, and stopping the driving of the motor within a predetermined time after an alarm is generated based on the inputted liquid feeding pattern. Further, the method is characterized by further including the step of detecting the capacity of the syringe. Further, it is characterized by further including the step of setting the manufacturer name of the syringe. Further, the method is characterized by further including a step of inputting and / or selecting a drug name. The computer-readable storage medium in which the control program of the liquid delivery method of the syringe pump of the present invention is stored has a program code for controlling the step of inputting a fluid delivery pattern and a program code for controlling the step of setting the closing pressure lower limit value. The program code that controls the step of injecting the drug solution in the syringe by pressing the pusher of the syringe to drive the motor based on the input liquid transfer pattern and below the set lower limit value of the closing pressure. And a program code for controlling the step of stopping the driving of the motor within a predetermined time after the alarm is generated based on the inputted liquid feeding pattern. Further, the method is characterized by further including program code for controlling the step of detecting the volume of the syringe. Further, it is characterized by further including a program code for controlling the step of setting the manufacturer name of the syringe.

The syringe pump of the present invention is also characterized in that the predetermined time can be changed according to the liquid delivery pattern and / or the drug name. Further, the lower limit value is characterized by being arbitrarily settable. The blocking pressure is characterized by being calculated by a moving average.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of the present invention will be described below with reference to the accompanying drawings. Figure 1 shows a syringe pump 1
3 is an external perspective view of FIG. 1 with the operation panel unit 2f facing forward so that the setting dial 6 for setting the flow rate or the like that is normally operated with the right hand can be seen.

In this figure, the syringe pump 1 is
It is a trace continuous delivery pump for the purpose of delivering (injecting) medicinal solutions such as chemotherapeutic agents such as nutritional supplementation, blood transfusion, cancer treatment, anesthetics, etc. in ICU, CCU, NICU, with flow rate display etc. The operation panel portion 2f for performing the operation is provided so as to be substantially concentrated on the upper surface as shown in the figure, which improves the operability.

The operation panel 2f is basically covered with an embossed sheet cover, and has a drip-proof design that satisfies the JIS0920 drip-proof test. For example, it is possible to easily wipe inadvertently spilled chemicals. It has a high drip-proof property to prevent chemicals and the like from entering the inside. For this purpose, the upper cover 2 and the lower cover 3 are integrally molded from a molding resin material having chemical resistance, and a rubber seal 4 made of, for example, a silicone elastomer is interposed between the connecting surfaces of the respective covers 2 and 3. With the structure of screwing, foreign matter such as liquid is prevented from entering the inside.

Further, in order to place importance on high precision of liquid transfer and improvement of operability, precise injection operation control by microcomputer control can be realized, and an operation indicator provided so as to project upward at a position easily visible from the outside. 7 is multi-colored in red or green, blinks, or is lit in rotation so that its operating state and alarm state can be viewed (monitored) from a distance, thus ensuring safety. In addition, it has a built-in buzzer and is equipped with various alarm functions for safety.

Further, since it is small and lightweight, it is easy to carry, and it is designed to be convenient to use even when a plurality of units are used at the same time. Furthermore, by turning the setting dial 6 on the right side of the device, numerical values such as the infusion flow rate (mL / h) and the infusion volume (mL) according to the rotation speed and the rotation direction can be set in a short time. , The display part 1 of the display panel
The set quantity value can be displayed in 1, so that when the setting of the numerical value such as the flow rate is changed, it can be easily performed with one action by operating the setting dial 6.

Furthermore, the shape is such that it can be used in multiple times (many combined), and it has a design that is easy to use and can be built up. The weight is about 1.8 kg, and the power source is an AC commercial power source and a built-in battery. There are 3 systems of DC12V. The built-in battery has a charging time of 15 hours (hours), and is covered with a lid at the bottom of the lower cover 3 so as to be easily replaceable from the outside, and is detachably provided by connecting with a connector. The replacement life is 3 years or more, while the charge control is trickle charging. In addition, over-discharge / charging prevention is achieved through cell damage detection / cell damage safety measures for rechargeable batteries. A heat-resistant (Ni-Cd) battery is used, and a new battery can be operated for 180 minutes or more until an alarm is issued and 210 minutes or more until shutdown.

Further, a display unit 10 for injecting a drug such as μg / kg / min, mg / kg / h, etc. per body weight, and a display unit 11 for each of the flow rate, the planned amount, and the integrated amount, etc. are provided on the operation panel 2f. On the other hand, while the setting dial 6 is provided, a recess 6e is formed so that it can be easily removed for cleaning, and the toe can be put in this part and rotated to move to the outside to be removed. Is configured.

Next, in order to set the main body (not shown) of the syringe, the upper cover 2 has a slit portion on which a syringe stage 2a and a flange portion (not shown) integrally formed with the main body of the syringe are set. While 2c is integrally injection-molded, a clamp column 2b (shown by a broken line) for rotatably supporting the clamp 5 is also integrally formed.

The slider assembly 50, which is driven in the direction of arrow A4 in the drawing, reciprocates on the recess 2d of the case, while the slider feed mechanism shown by the broken line shows a pipe shaft and an inner clutch shaft which will be described later. Is connected and fixed at the end portion of the syringe assembly, and is configured such that a pusher (not shown) of the syringe can be easily attached or detached by manually operating the clutch lever 52 of the slider assembly 50.

FIG. 2 is a plan view of the operation panel section 2f. In this figure, a power switch 15, an AC / DC lamp 16 and a battery lamp 17 are centrally arranged at the left end. Next to these lamps, a medicine injection display unit 10 per body weight is arranged, but a model without the medicine injection display unit 10 per body weight can be sufficiently used, and therefore, there is a model which does not have it. The unit injection switch (also serving as a display on / off switch) 10a and an item selection switch 10b are provided in the drug injection / display unit 10 per body weight.

On the other hand, a clamp 5 is provided on the display unit 10.
When it is set by using the syringe, the vertical movement of the clamp is converted into an electric signal and then automatically measured by the syringe diameter detecting means 50 for detecting the syringe outer diameter (volume), and the volume of the set syringe is measured. (Volume) 10 cc (mL), 2
0 cc (mL), 30 cc (mL), 50 cc (mL),
A syringe display lamp (syringe display section) 18 for displaying the name of the syringe manufacturer is provided.

Further, below the clamp 5, there is provided an operation indicator 7 formed from a transparent acrylic resin or the like so as to have a shape protruding upward, and the built-in red and green are appropriately illuminated. Light emitting diodes 7a-7d
Lights up or blinks, and the light is scattered inside so as to rotate in the direction of the arrow shown in the figure so that the liquid feeding operation state can be displayed electronically.

Next to the clamp 5, there are provided indicator lamps 19a, 19b, 19c for switching and displaying the set detection pressure by the blockage detecting mechanism provided in the syringe pump in three steps. Next to these lamps, a remaining amount alarm lamp 20, a battery alarm lamp 22 and the like are concentratedly arranged. In addition, a closing pressure monitor display unit 19d is provided which lights up an alarm and displays an alarm when the closing pressure falls below a set value (mmHg). A pusher / clutch disengagement display portion 19e for displaying disengagement of the pusher and disengagement of the clutch is also provided.

Next to these lamps,
A 7-segment LED display unit 11 including integrated amount lamps 23, 24, and 25 is provided. This display unit 11
The maker name set and input by the maker input means 40 or the maker name read by the identification information reading means (not shown) is displayed on the screen as symbols or characters.

A display changeover switch 26 and an integration clear switch 27 are provided on the right side of the display section 11. Then, below the display unit 11, the fast-forward switch 30 is provided.
A start switch 29 and a stop / silence switch 28 are provided. Further, there is also provided selection means (selection switch) (not shown) capable of selecting either or both of the remaining position alarm and the remaining time (end time) alarm. Further, a manual switch 31 for maintaining the blood drug concentration at a predetermined value is provided. By pressing this manual switch 31 for a predetermined time (1 to 3 seconds),
The blood drug concentration can be maintained at a predetermined value.

In order to set the flange of the syringe in the slit 2c, the flange of the syringe is put in the slit 2c. After that, the main body S (not shown) of the syringe is set on the syringe stage 2a, and then the syringe is clamped by the clamp.

The above slit 2c and syringe stage 2
Further, a circular arc groove portion having a smaller diameter is integrally formed with a, so that a small-capacity small-diameter syringe can be held immovably. This completes the setting of the syringe.
At this time, attached to the syringe, the manufacturer of the syringe,
Identification information that identifies the type of syringe, including syringe volume
A reading means for reading (bar code or the like) may be provided to identify the syringe and / or the drug solution contained in the syringe.

Subsequently, the clutch is released to move the slider. At this time, the slider assembly 50 shown in FIG.
When the clutch lever 52 is pressed, the slider can be moved by hand. Therefore, when the pusher (not shown) of the syringe is brought into contact with the slider assembly 50 and then the clutch lever 52 is released, the left and right hooks (not shown) press the pusher SP (not shown) of the syringe S (not shown). ) Will be automatically retained. That is, when the clutch lever 52 is released, the hook of the slider is in a state of sandwiching the pusher of the syringe.
The above is the basic set operation.

Further, the slider feeding mechanism is further provided with a blockage detecting mechanism. Syringe presser (not shown)
Although the drug solution contained therein can be injected by pressing, the force acting in the opposite direction is generated at this time by the action of resistance in the syringe and other infusion channels.

In this way, the generated force becomes a deflection of a pressure sensor (not shown) using a strain gauge or the like, and this mechanical deflection is converted into an electrical output, and a storage means (E ² PROM). , RAM) 100 below the set value (threshold value) set for each manufacturer and syringe size (syringe outer diameter) stored in the operation indicator 7 as an alarm notifying an abnormal state and an alarm sound (buzzer). Occurs (rings).

Further, the load setting caused by the resistance in the syringe and other infusion liquid flow paths is set by the three display lamps 19a, 19 provided on the display panel on the upper cover 2.
The load setting value is displayed in the following manner by being switched and displayed in three steps by b and 19c. The load setting values are syringe outer diameter D (cm), syringe size (syringe capacity) (mL), and syringe cross-sectional area A (c
m ² ), considering the sliding resistance Fs (kgf) of the syringe, etc.
Table for each syringe manufacturer of more than 10
Although the value (kgf / cm ² ) is stored in the storage means (memory) 100 as the default value, the setting means (setting dial) 6 can arbitrarily set and change the values of the upper limit range and the lower limit range.

Further, a conversion value Fp (kgf) [= P (kgf / c) of a threshold value (lower limit occlusion value) P (kgf / cm ² ) selected based on the specified and set syringes tabulated.
m ² ) · A (cm ² ) + Fs (kgf)] and the pressure value (load F (kgf)) detected by the above-mentioned pressure sensor (not shown) through the slider are compared. This load F (kg
f) is preferably a predetermined sampling period, eg
It can be obtained by removing a noise component due to rattling of a syringe, a driving unit, etc. by sampling a predetermined number, for example, 16 samples every 0.05 seconds and obtaining a moving average value. The obtained result is displayed as a segment on the segment display unit 19d, an alarm (alarm) indicating that an event below a predetermined threshold value has occurred, is displayed by blinking the operation indicator 7, etc., and is displayed for a predetermined time (second / second). After that, stop driving the motor.

Further, in the syringe pusher / clutch disengagement detection mechanism, the clutch lever 52 is erroneously grasped during the feed operation of the pump, and the teeth of the half nut (not shown) and the lead screw (not shown) that constitute the clutch are provided. An alarm sound is generated when the matching state is cut off, or when the same occurs due to the action of some load or the like, and the abnormality is notified by blinking the pusher / clutch disengagement display portion 19e.

Next, the data of the syringe cross-sectional area A (cm ² ) and the syringe outer diameter D (cm) are stored in the CPU (replaceable memory) (E ² PROM) for one or more syringe makers and each size (mL). ) Stores and holds the syringe cross-sectional area data. In addition, drug injection per body weight (gamma)
Injection, scheduled injection, and alarm / drive status display are provided. The alarm is displayed three-dimensionally, and the LED lighting portion of the operation indicator 7 is rotated in the drive status.

When the setting dial 6 is rotated in the clockwise direction, various setting values are increased and displayed on the display section 11 shown in FIGS. Similarly, when the setting dial 6 is rotated counterclockwise, the set value is displayed on the display unit 11 so as to be lowered.

Specifically, when the display changeover switch 26 provided on the display panel of FIG. 2 is pressed, the flow rate lamp 23 and the planned amount lamp 24 are sequentially turned on so that each setting can be performed. There is.

Therefore, when the flow rate is set, the display changeover switch 26 is pressed so that the flow rate lamp 23 is turned on, and then the setting dial 6 is rotated. As a result, the set value is displayed on the display unit 11. This display range is 0.0-1200mL
/ H (~ 999.9: 0.1 mL / h step) (10
(0 to 1 mL / h step), the minimum flow rate is set to 0.0 and a wide injection range can be set. In addition, we are able to guarantee each type of syringe from each manufacturer. Further, when the flow rate setting value is "0", the buzzer issues a one-shot alarm and the operation indicator lights up in red for a moment to prevent the start. Further, even if the flow rate set value exceeds the drivable flow rate range, the buzzer issues a one-shot alarm and the operation indicator lights up in red for a moment to prevent the start.

The integrated amount is added up from the pulse count value of the encoder fixed to the output shaft of the motor 35, while the fast-forward amount fast-forwarded after the fast-forward switch 30 is pressed is added.

The amount of injection is set according to body weight: 0.0 to 30
0.0 Kg (0.1 Kg step), drug amount; 0.0
~ 999.9 mg (0.1 mg step), solution volume;
0.0 to 999.9 ml (0.1 mL step), dose: 0.00 to 99.99 (μg / kg / min or mg / kg / h) (0.01 step) .

The minimum flow rate is displayed from 0.0 and the flow rate is automatically calculated and displayed when the body weight, the drug amount, the solution amount, and the dose amount are input, and the flow rate starts at the displayed flow rate. You can do it. This calculation result is a settable flow rate (0.1 mL / h or more, 1200 mL
/ H or less), the flow rate display on the display unit 11 becomes a display other than "----", and the buzzer sounds one shot before and after this The indicator lights up in red for a moment so that pump operation cannot be started.

On the other hand, when the calculation result is within 1200 mLl / h, the calculation result is displayed.
It is the above calculation result, and the type of syringe is 10
When it is automatically detected that it is 30 cc, the buzzer sounds one shot even if the start switch 29 is pressed,
The operation indicator lights up in red for a moment so that it cannot start.

Next, when the fast-forward switch 30 is pressed, the flow rate of the solution is increased, and in the case of the syringe 50cc, it is set to 1
200 mL / h, 500 mL / h for 30 cc,
400 ml / h for 20 cc, 10 cc syringe
In the case of, the liquid transfer is performed at 300 mL / h.

The display range for setting the planned amount is 0.0 to 9
99.9 mL (0.1 mL step), minimum planned amount →
The value is 0.0, and the operation can be selected by an internal selection switch. And planned amount = 0.0
In this case, when the start switch 29 is pressed, the buzzer gives a one-shot alarm, the operation indicator lights up in red for a moment, and the planned amount lamp 24 of the planned amount LED blinks so that it cannot be started. .

Further, when the planned amount ≦ the integrated amount, the planned amount lamp 2
The LED of 4 is flashing and a buzzer is issued to prevent continuation. Further, when the predetermined amount ≦ the integrated amount during the injection, the LED of the predetermined amount lamp 24 blinks and a buzzer is issued to automatically switch to the KOR (keep open rate) operation. At this time, the flow rate is KOR (0.
Since 1 mL / h) is displayed, pressing the stop / silence switch 28 once silences the sound. When the KOR operation is continued, there is a re-alarm, and when the stop switch 28 is pressed again, the operation stops.

On the other hand, the initial display when the power to the apparatus is turned on is "0" mL except in the memory mode.

Basically, the priority order of ringing is (a) blockage (upper limit / lower limit), syringe disengagement, clutch disengagement, (b) battery voltage drop (2 minutes, 4 minutes,
6 minutes, 8 minutes, 10 minutes, 10 minutes or more), (c) push-off warning (remaining quantity warning), and (d) forgotten start sound are set in order of high priority. Also, when multiple alarms are issued, the alarms are sequentially switched to the higher one. Similarly, when multiple alarms are generated during mute, an alarm with a high priority is to be issued, and key clicks and one-shot alerts are issued during intermittent alarms such as a start forgetting sound. Is able to interrupt and ring.

On the other hand, referring again to FIG. 2, the operation of the operation indicator 7 is as follows: (a) During normal operation, the built-in light emitting diode 7a is operated at four different speeds corresponding to the set flow rate.
~ 7d sequentially flashes in the clockwise direction in green. (B) While the operation is stopped, the green light turns off except for the red light when an alarm is issued. (C) When forgetting to start, all the light emitting diodes 7a to
7d flashes red. (D) When it receives communication from the outside, it flashes in green for a moment.

The first is the explanation of the use of the syringe pump described above.
This embodiment will be described with reference to the flowchart of FIG. 3 and the block diagram of FIG. As a preparatory step, first check the tools, and then use the syringe pump 1 and the attached pole clamp and A
C Make sure that you have the power cable, the infusion stand, the syringe containing the drug solution, and the indwelling needle (all not shown). After this, the pole clamp is fixed to the infusion stand, and the pole clamp is firmly fixed to the infusion stand. For this purpose, the mounting screw of the pole clamp is inserted and fixed in the screw hole at the bottom of the syringe pump. Next, connect the AC power cable to the AC inlet 8 on the right side of the main unit, and plug the AC100V with ground terminal.
Plug into the outlet.

When the AC power source is connected, the battery lamp 17 lights up, indicating that the built-in battery is being charged.

Example 1 will be described with reference to the flow chart of FIG. The flowchart of FIG. 4A shows a syringe pump having functions of setting a syringe manufacturer name, detecting a syringe diameter (outer diameter), and setting (selecting) a medicine name. Therefore, when the power switch 15 is pressed for about 1 second to turn on the power, all the lamps blink three times and the buzzer sounds again to automatically perform self-check (step S1). At this time, while the AC / DC lamp 16 is turned on, each of the display lamps 23 for displaying the flow rate, the planned amount, and the integrated amount,
24 and 25 are lit. In addition, a preset syringe maker is displayed as numbers for about 3 seconds on the display unit 11 for the flow rate, the planned amount, and the integrated amount. Be sure to check whether the set syringe matches the set manufacturer name.

If the syringe manufacturer is not appropriate, the manufacturer name is input and set in the manufacturer name input section (input means) 40 (step S2). The manufacturer name that has been set and input is displayed on the display unit 11 as characters or symbols.

After the elapse of a predetermined time, the number of the syringe manufacturer on the display unit 11 for the flow rate / planned amount / integrated amount disappears and the display unit 11 displays “0.0”. The operation indicator 7 is off at this time.

On the other hand, the syringe type display lamps 18 indicate that no syringes (not shown) are attached in a state where all the four built-in display lamps are blinking to prompt the syringe set. The syringe is set when all the above indications are confirmed.

After the syringe is connected to the injection line (tube) and the syringe filled with the drug solution in an aseptic environment, the main body of the syringe is set on the stage 2a and the clamp 5 engages it.

Then, the flange of the syringe is inserted into the slit 2c in order to set the flange (not shown) of the syringe in the slit 2c. After that, the main body S of the syringe
Is set on the syringe stage 2a, and then the clamp 5 is rotated in a predetermined direction, the locked state is released and the syringe clamp is performed, and the syringe diameter (syringe) is detected by the set syringe diameter detecting means (detection unit) 50. Volume: 10 mL, 20 mL, 50 mL, etc.) is automatically detected (step S3).

Then, the clutch lever of the slider assembly is pushed to release the clutch to move the slider. At this time, if the clutch lever of the slider is pushed, the slider can be moved by hand.

Therefore, when the pusher of the syringe is brought into contact with the slider assembly and then the clutch lever is released, the left and right hooks automatically hold the pusher.
That is, when the clutch lever is released, the hook of the slider is in a state of sandwiching the pusher of the syringe.

After the syringe is set, priming is performed. This priming must be performed before the patient is punctured, and when the fast-forward switch 30 is pressed, the operation indicator 7 is rotatably displayed, the pump operation is started, and the liquid medicine comes out from the tip of the indwelling needle. The fast-forward switch 30 is continuously pressed to feed the drug solution to the tip of the indwelling needle. At this time, the integrated amount lamp 25 blinks.

Further, the display unit 11 for displaying the flow rate, the planned amount, and the integrated amount.
During fast-forwarding, the integrated amount lamp 25 blinks and the priming amount is displayed on the flow rate / planned amount / integrated amount display unit 11. This priming amount is added to the integrated amount in 0.1 ml steps. Here, by pressing the integration clear switch 27, the integration amount can be cleared to "0".

This priming is important because it is important to eliminate the gap between the syringe and the main body so that the working surface of the slider assembly 50 of the main body comes into contact with the pusher of the syringe without any gap.

After the above priming is completed, the liquid feed pattern (injection amount) is set by the setting input means (input section) 60 (step S4). At this time, it is confirmed that the flow rate lamp 23 is turned on. To do. When the flow rate lamp 23 is not lit, the display changeover switch 26 is pressed to bring the flow rate lamp 23 into the lit state.

After that, the setting dial 6 forming a part of the input unit 60 is turned to set the flow rate per hour. At this time, the setting dial 6 is turned to prevent malfunction of the setting dial operation and ensure safety. From the beginning, the value does not change for half a lap. Also, when the number of laps exceeds half, the buzzer sounds and the numerical value changes.

To increase or decrease this numerical value, the numerical value decreases when the setting dial 6 is turned to the front, and the numerical value increases when the setting dial 6 is turned to the rear. Further, when the setting dial 6 is turned while the stop / silence switch 28 is pressed, the upper digit of the numerical value changes.

Regarding the syringe type and the maximum flow rate, the maximum flow rate that can be set is set depending on the type of syringe. For example, the maximum flow rate of a 30 mL syringe is 300 mL /
It is h. Therefore, when a value larger than the maximum flow rate is set and the start switch 29 is pressed, the flow rate setting value blinks so that the injection is not started. Therefore, the setting is performed again and the setting is completed. Next, a drug registered in advance is selected or the drug name is read from a barcode, tag, etc. attached to the syringe (step S5).

The blockage detection pressure level is set by pressing the stop / silence switch 28 and the display changeover switch 26. First, to change the setting of the occlusion detection pressure level, press the stop / silence switch 28 while simultaneously pressing the display changeover switch 2.
When 6 is pressed, “P
"***" is displayed and the setting mode is entered. While pressing the stop / silence switch 28 as it is, the display changeover switch 2
When 6 is released and pushed, the closing pressure setting value lamp 19a,
Printed characters "L" (low) and "M" near 19b and 19c
Since (medium) and "H" (high) are turned on in order, the desired level of the closing pressure (upper limit range, lower limit range) is set (selected) and input (step S6). The above *** means L, M, H
Is a numerical value corresponding to. Thus, the stop / silence switch 28 and the display changeover switch 26 function as a closing pressure selecting means.

Selection (selection) The input occlusion pressure level,
A blocking pressure threshold value (upper limit value and / or lower limit value) that has been tabulated in advance is automatically selected based on the syringe diameter (capacity) and the syringe manufacturer name, and the delivery of the drug solution is started.

A predetermined number (16) are sampled continuously in a predetermined sampling cycle (for example, every 0.05 seconds), the moving average value is calculated, and it is determined whether or not the occlusion pressure exceeds a threshold value ( Step S7).

When the closing pressure falls below the lower limit value, an alarm is generated and the operation indicator 7 lights up in red.
After blinking and giving a notification, the motor drive is stopped after a lapse of a predetermined time (second / minute) (step S8).

(Second Embodiment) An explanation will be given with reference to the flow chart of FIG. 4 (b). The flow chart of FIG. 4B is for the case of using a specific syringe (a syringe of a specific volume (outer diameter) (mL) such as a filled container containing a specific drug). Therefore, when the power switch 15 is pressed for about 1 second to turn on the power, all the lamps blink three times and the buzzer sounds again to automatically perform self-check (step S1). At this time, the AC / DC lamp 16
Is turned on, while the display lamps 23, 24, 25 for the flow rate / scheduled amount / integrated amount are turned on.

After the syringe is connected to the injection line (tube) and the syringe filled with the drug solution in an aseptic environment, the main body of the syringe is set on the stage 2a and the clamp 5 engages it. Then, the flange of the syringe is inserted into the slit 2c in order to set the flange (not shown) of the syringe in the slit 2c. Then, the main body S of the syringe is set on the syringe stage 2a. Then, the clutch lever of the slider assembly is pushed to release the clutch and move the slider. At this time, if the clutch lever of the slider is pushed, the slider can be moved by hand. Therefore, when the pusher of the syringe is brought into contact with the slider assembly and then the clutch lever is released, the left and right hooks automatically hold the pusher. That is, when the clutch lever is released, the hook of the slider is in a state of sandwiching the pusher of the syringe. After setting the syringe, perform priming. This priming must be performed before the patient is punctured, and when the fast-forward switch 30 is pressed, the operation indicator 7 is rotatably displayed, the pump operation is started, and the liquid medicine comes out from the tip of the indwelling needle. The fast-forward switch 30 is continuously pressed to feed the drug solution to the tip of the indwelling needle. At this time, the integrated amount lamp 25 blinks. In addition, the display unit 11 for the flow rate / planned amount / integrated amount blinks the integrated amount lamp 25 during fast-forwarding,
The priming amount is displayed on the integrated amount display unit 11.
This priming amount is added to the integrated amount in 0.1 ml steps. Here, by pressing the integration clear switch 27, the integration amount can be cleared to "0".
This priming is important because it eliminates the gap between the syringe and the main body so that the working surface of the slider assembly 50 of the main body comes into contact with the pusher of the syringe without any gap.

After the above priming is completed, the liquid feeding pattern (injection amount) is set by the setting input means (input section) 60 (step S4). At this time, it is confirmed that the flow rate lamp 23 is turned on. To do. When the flow rate lamp 23 is not lit, the display changeover switch 26 is pressed to bring the flow rate lamp 23 into the lit state.

After that, the setting dial 6 forming a part of the input unit 60 is turned to set the flow rate per hour. At this time, the setting dial 6 is turned to prevent malfunction of the setting dial operation and ensure safety. From the beginning, the value does not change for half a lap. Also, when the number of laps exceeds half, the buzzer sounds and the numerical value changes. To increase or decrease this value, turn the setting dial 6 toward you to decrease the value, and turn it toward the back to increase it. Also, stop / mute switch 2
If the setting dial 6 is turned while pressing 8, the upper digit of the numerical value changes.

The blockage detection pressure level is set by pressing the stop / silence switch 28 and the display changeover switch 26. First, to change the setting of the occlusion detection pressure level, press the stop / silence switch 28 while simultaneously pressing the display changeover switch 2.
When 6 is pressed, “P
"***" is displayed and the setting mode is entered. While pressing the stop / silence switch 28 as it is, the display changeover switch 2
When 6 is released and pushed, the closing pressure setting value lamp 19a,
Printed characters "L" (low) and "M" near 19b and 19c
Since (medium) and "H" (high) are turned on in order, the desired level of the closing pressure (upper limit range, lower limit range) is set (selected) and input (step S6). The above *** means L, M, H
Is a numerical value corresponding to. Thus, the stop / silence switch 28 and the display changeover switch 26 function as a closing pressure selecting means.

The occluding pressure threshold value (upper limit value and / or lower limit value) tabulated in advance is automatically selected, and the delivery of the drug solution is started. Predetermined sampling period (for example, 0.05
A predetermined number (16) are continuously sampled every second), the moving average value is calculated, and it is determined whether or not the closing pressure exceeds the threshold value (step S7). If the occlusion pressure falls below the lower limit, an alarm will be generated and the operation indicator 7
Lights up in red (flashes), and after notification, a predetermined time (seconds / minute)
After a lapse of time, the motor drive is stopped (step S8).

(Third Embodiment) The third embodiment will be described with reference to the flowchart of FIG. The flowchart in FIG. 4C is for a syringe pump that injects different drugs using a syringe with a specific syringe diameter (outer diameter) of a specific manufacturer. Therefore, when the power switch 15 is pressed for about 1 second to turn on the power, all the lamps blink three times and the buzzer sounds again to automatically perform self-check (step S1). On the other hand, the syringe type display lamp 18 prompts the syringe set by displaying that no syringe (not shown) is attached while all the four built-in display lamps are blinking. The syringe is set when all the above indications are confirmed. After the syringe is connected to the injection line (tube) and the syringe filled with the drug solution in an aseptic environment, the main body of the syringe is set on the stage 2a and the clamp 5 engages it. continue,
Insert the flange of the syringe into the slit 2c to set the flange (not shown) of the syringe into the slit 2c. Then, the main body S of the syringe is attached to the syringe stage 2a.
When the clamp 5 is rotated in a predetermined direction after being set up, the locked state is released and the syringe clamp is performed.

Next, the clutch lever of the slider assembly is pushed to release the clutch to move the slider. At this time, if the clutch lever of the slider is pushed, the slider can be moved by hand. Therefore, after making the pusher of the syringe contact the slider assembly,
When the clutch lever is released, the left and right hooks will automatically hold the pusher. That is, when the clutch lever is released,
The hook of the slider is in a state of sandwiching the presser of the syringe. After setting the syringe, perform priming. This priming must be performed before the patient is punctured, and when the fast-forward switch 30 is pressed, the operation indicator 7 is rotatably displayed, the pump operation is started, and the liquid medicine comes out from the tip of the indwelling needle. The fast-forward switch 30 is continuously pressed to feed the drug solution to the tip of the indwelling needle. At this time, the integrated amount lamp 25 blinks. Further, in the flow rate / scheduled amount / integrated amount display unit 11 during fast-forwarding, the integrated amount lamp 25 blinks and the priming amount is displayed on the flow rate / scheduled amount / integrated amount display unit 11. This priming volume is 0.1 ml
It is added to the integrated amount in steps. Here, by pressing the integration clear switch 27, the integration amount can be cleared to "0". This priming is important because it eliminates the gap between the syringe and the main body so that the working surface of the slider assembly 50 of the main body comes into contact with the pusher of the syringe without any gap.

After the above priming is completed, the liquid feed pattern (injection amount) is set by the setting input means (input section) 60 (step S4). At this time, it is confirmed that the flow rate lamp 23 is turned on. To do. When the flow rate lamp 23 is not lit, the display changeover switch 26 is pressed to bring the flow rate lamp 23 into the lit state. After that, the setting dial 6 forming a part of the input unit 60 is turned to set the flow rate per hour. At this time, in order to prevent malfunction of the setting dial operation and ensure safety,
The number does not change for half a lap after starting turning. Also, when the number of laps exceeds half, the buzzer sounds and the numerical value changes. To increase or decrease this value, turn the setting dial 6 toward you to decrease the value, and turn it toward the back to increase it. Further, when the setting dial 6 is turned while the stop / silence switch 28 is pressed, the upper digit of the numerical value changes. next,
Select the drug registered in advance or read the drug name from the barcode, tag, etc. attached to the syringe (step S
5).

The blockage detection pressure level is set by pressing the stop / silence switch 28 and the display changeover switch 26. First, to change the setting of the occlusion detection pressure level, press the stop / silence switch 28 while simultaneously pressing the display changeover switch 2.
When 6 is pressed, “P
"***" is displayed and the setting mode is entered. While pressing the stop / silence switch 28 as it is, the display changeover switch 2
When 6 is released and pushed, the closing pressure setting value lamp 19a,
Printed characters "L" (low) and "M" near 19b and 19c
Since (medium) and "H" (high) are turned on in order, the desired level of the closing pressure (upper limit range, lower limit range) is set (selected) and input (step S6). The above *** means L, M, H
Is a numerical value corresponding to. Thus, the stop / silence switch 28 and the display changeover switch 26 function as a closing pressure selecting means.

Selection (selection) The input occlusion pressure level,
A blocking pressure threshold value (upper limit value and / or lower limit value) that has been tabulated in advance is automatically selected based on the syringe diameter (capacity) and the syringe manufacturer name, and the delivery of the drug solution is started. A predetermined number (16 units) are sampled continuously in a predetermined sampling cycle (for example, every 0.05 seconds), the moving average value is calculated, and it is determined whether or not the occlusion pressure exceeds a threshold value (step S7). . When the closing pressure falls below the lower limit, an alarm is generated and the operation indicator 7 lights up in red.
After blinking and giving a notification, the motor drive is stopped after a lapse of a predetermined time (second / minute) (step S8).

(Embodiment 4) Description will be made with reference to the flow chart of FIG. The flowchart in FIG. 4D is a syringe pump that uses a syringe manufactured by a specific manufacturer and that has a function of automatically detecting the syringe diameter (outer diameter) and setting (selecting) a drug name. Therefore, to turn on the power, the power switch 15
When is pressed for about 1 second to turn on the power, all the lamps blink three times, the buzzer sounds again, and self-check is automatically performed (step S1). After the elapse of a predetermined time, the number of the syringe manufacturer on the display unit 11 for the flow rate / planned amount / integrated amount disappears, and “0.0” is displayed on the display unit 11. The operation indicator 7 is off at this time. If the syringe is not attached, a message that the syringe (not shown) is not attached is displayed to prompt the syringe set. The syringe is set when all the above indications are confirmed.
After the syringe is connected to the injection line (tube) and the syringe filled with the drug solution in an aseptic environment, the main body of the syringe is set on the stage 2a and the clamp 5 engages it. Then, the flange of the syringe is inserted into the slit 2c in order to set the flange (not shown) of the syringe in the slit 2c. After that, when the main body S of the syringe is set on the syringe stage 2a and then the clamp 5 is rotated in a predetermined direction, the locked state is released, the syringe clamp is performed, and the set syringe diameter detection means (detection unit) 50 syringe diameter (syringe capacity: 10 m
L, 20 mL, 50 mL, etc.) are automatically detected (step S3).

Next, the clutch lever of the slider assembly is pushed to release the clutch to move the slider. At this time, if the clutch lever of the slider is pushed, the slider can be moved by hand. Therefore, after making the pusher of the syringe contact the slider assembly,
When the clutch lever is released, the left and right hooks will automatically hold the pusher. That is, when the clutch lever is released,
The hook of the slider is in a state of sandwiching the presser of the syringe. After setting the syringe, perform priming. This priming must be performed before the patient is punctured, and when the fast-forward switch 30 is pressed, the operation indicator 7 is rotatably displayed, the pump operation is started, and the liquid medicine comes out from the tip of the indwelling needle. The fast-forward switch 30 is continuously pressed to feed the drug solution to the tip of the indwelling needle. At this time, the integrated amount lamp 25 blinks.

Further, the display unit 11 for displaying the flow rate, the planned amount and the integrated amount
During fast-forwarding, the integrated amount lamp 25 blinks and the priming amount is displayed on the flow rate / planned amount / integrated amount display unit 11. This priming amount is added to the integrated amount in 0.1 ml steps. Here, by pressing the integration clear switch 27, the integration amount can be cleared to "0". This priming is important because it eliminates the gap between the syringe and the main body so that the working surface of the slider assembly 50 of the main body comes into contact with the pusher of the syringe without any gap. After the above priming is completed, the liquid feed pattern (injection amount) is set by the setting input means (input unit) 60 (step S4). At this time, it is confirmed that the flow rate lamp 23 is turned on. When the flow rate lamp 23 is not lit, the display changeover switch 26 is pressed to bring the flow rate lamp 23 into the lit state.

After that, the setting dial 6 forming a part of the input unit 60 is turned to set the flow rate per hour. At this time, the setting dial 6 is turned to prevent malfunction of the setting dial operation and ensure safety. From the beginning, the value does not change for half a lap. Also, when the number of laps exceeds half, the buzzer sounds and the numerical value changes. To increase or decrease this value, turn the setting dial 6 toward you to decrease the value, and turn it toward the back to increase it. Also, stop / mute switch 2
If the setting dial 6 is turned while pressing 8, the upper digit of the numerical value changes.

Regarding the syringe type and the maximum flow rate, the maximum flow rate that can be set is set depending on the type of syringe. For example, the maximum flow rate of a 30 mL syringe is 300 mL /
It is h. Therefore, when a value larger than the maximum flow rate is set and the start switch 29 is pressed, the flow rate setting value blinks so that the injection is not started. Therefore, the setting is performed again and the setting is completed. Next, a drug registered in advance is selected or the drug name is read from a barcode, tag, etc. attached to the syringe (step S5). To set the blockage detection pressure level, press the stop / silence switch 28,
This is done by pressing the display changeover switch 26. First, when changing the setting of the blockage detection pressure level, pressing the display changeover switch 26 at the same time while pressing the stop / silence switch 28 causes "P ***" to be displayed on the display unit 11 for the flow rate / scheduled amount / integrated amount. ,
Enter the setting mode. While pressing the stop / silence switch 28 as it is, the display changeover switch 26 is released and pressed to print “L” (low) / “M” (middle) of the print characters near the closing pressure set value lamps 19a, 19b, 19c. ) ・ "H" (high) lights up in order, so input (set) input of desired occlusion pressure level (upper limit range, lower limit range).
6). The above *** is a numerical value corresponding to the above L, M, and H. Thus, the stop / silence switch 28 and the display changeover switch 26 function as a closing pressure selecting means.

Selection (selection) The input occlusion pressure level,
A blocking pressure threshold value (upper limit value and / or lower limit value) that has been tabulated in advance is automatically selected based on the syringe diameter (capacity) and the syringe manufacturer name, and the delivery of the drug solution is started. A predetermined number (16 units) are sampled continuously in a predetermined sampling cycle (for example, every 0.05 seconds), the moving average value is calculated, and it is determined whether or not the occlusion pressure exceeds a threshold value (step S7). . When the closing pressure falls below the lower limit, an alarm is generated and the operation indicator 7 lights up in red.
After blinking and giving a notification, the motor drive is stopped after a lapse of a predetermined time (second / minute) (step S8).

The chemical resistance was not wiped with alcohol, but the outer layer was ABS grade V0 so as to have a chemical resistance equivalent to that of alcohol, and the back side was printed so that the name plate, printed characters, indications, etc. would not disappear. I dealt with it.

The driving thrust (force for pushing the pusher) is about 15 Kg · f at the maximum and can withstand about 20 Kg · f, and the machine (feed) accuracy can be made highly accurate within ± 1% by actual measurement. In addition, it was made possible to guarantee each type of syringe manufacturer.

Specifically, by actually measuring the moving amount of the slider, (A) flow rate <1.0 mL / h 60 minutes (long-term); ± 5% or less (B) 1.0 mL / h ≤ flow rate < 5.0 mL / h 2 minutes observation window; ± 2%
Or less and 60 minutes (long-term); ± 1% or less (C) 5.0 mL / h ≤ flow rate of 2 minutes observation window; ± 1%
I did the following.

Further, the discharge amount was measured so that each type of each manufacturer can be guaranteed so that the flow rate accuracy is high within ± 3%. (A) 1.0 mL / h ≦ flow rate <5.0 mL / h 2 minutes observation window; ± 5%
Hereinafter (B) 1.0 mL / h ≦ flow rate 60 minutes (long-term); ± 3% or less (C) It was confirmed that 95% or more 10 minutes after the start. The injection amount display unit 10 per body weight is a liquid crystal with a backlight (yellow or green). It is a numerical display consisting of 7 segments each. Weight / Kg / Amount of drug / m
g · solution volume mL · dose · μg / kg / min or m
Display such as g / kg / h, weight; 7SEG 4 digits + decimal point 1SEG, drug amount; 7SEG 4 digits + decimal point 1SE
G, volume of solution; 7SEG 4 digits + decimal point 1SEG, dose;
7SEG 4 digits + decimal point 1SEG is displayed. When the normal injection mode is selected, the backlight of the entire screen goes off.

Further, the flow rate / accumulated amount / planned amount display section 11 is an LED display which is easy to see, and 7SEG 4 digits + decimal point 1SE.
When G and the γ mode is set, the flow rate display is automatically switched. Also, injection per body weight (μg / kg / mi
(n or mg / kg / h, etc.) While setting the mode, the flow rate display switches sequentially according to the set value. When the accumulated amount or the planned amount is displayed, it will automatically switch to the flow rate display if left for about 15 seconds. I have to.

The alarm is generated at the time of Er *, CPU runaway, switch operation and self-check, but it has an easy-to-understand tone and no discomfort. Furthermore, it is compatible with overseas standards and volume can be switched between 3 levels (panel operation). In addition, it is possible to store the set volume and display the volume level at the time of setting. Its maximum volume is 65 dB or more 1 m away, and it is also self-excited (to alert when the CPU runs out of control).
I have to. The result is written in the E ² PROM.

[0088]

As described above, according to the syringe pump of the present invention, the motor drive is not immediately stopped even when the detected closing pressure falls, and a predetermined time (predetermined seconds / predetermined minutes) as required. Since it is a syringe pump that will stop driving the motor later, it can properly issue an alarm.

[Brief description of drawings]

FIG. 1 is an external perspective view of a syringe pump body of the present invention.

FIG. 2 is a plan view of an operation panel unit 2f.

FIG. 3 is a block diagram of the syringe pump of the present invention.

FIG. 4 is a flowchart of the syringe pump of the present invention.

[Explanation of symbols]

DESCRIPTION OF SYMBOLS 1 ... Syringe pump main body, 2 ... Upper cover, 3 ... Lower cover, 4 ... Rubber seal, 5 ... Clamp, 6 ... Setting dial, 7 ... Operation indicator, 7a-7d ... Light emitting diode, 8 ... AC inlet, 9 ... DC Power connector, 10
… Injection setting display unit per body weight, 11… Flow rate / scheduled amount / accumulated amount display unit, 12 ... External communication connector, 13 ... Nurse call connector, 15 ... Power switch, 16 ... AC / DC
Lamp, 17 ... Battery lamp, 18 ... Syringe display lamp, 19a-19c ... Blocking lamp, 21 ... Remaining amount alarm lamp, 22 ... Battery alarm lamp, 23 ...
Flow rate lamp, 24 ... Scheduled quantity lamp, 25 ... Integrated quantity lamp, 26 ... Changeover switch, 27 ... Integrated clear switch, 28 ... Stop / silence switch, 29 ... Start switch,
30 ... Fast-forward switch, 52 ... Clutch lever

Claims (21)

[Claims] 1. A syringe pump for delivering a drug solution in a syringe according to a predetermined infusion pattern, comprising: a delivery pattern input means for entering a delivery pattern; and a closing pressure setting means for setting a closing pressure lower limit value. And a drive control means for driving and controlling the motor based on the inputted liquid feeding pattern to press the pusher of the syringe to inject the drug solution in the syringe, and the value falls below the set lower limit value of the closing pressure. That is detected, and the driving of the motor is stopped within a predetermined time after an alarm is generated based on the input liquid transfer pattern. 2. The syringe pump according to claim 1, further comprising syringe diameter detecting means for detecting the volume of the syringe. 3. The syringe pump according to claim 1, further comprising setting means for setting a manufacturer name of the syringe. 4. The syringe pump according to claim 1, further comprising means for inputting and / or selecting a drug name. 5. The syringe pump according to claim 1, wherein the predetermined time can be changed according to the liquid delivery pattern and / or the drug name. 6. The syringe pump according to claim 1, wherein the closing pressure lower limit value can be set arbitrarily. 7. The syringe pump according to claim 1, wherein the closing pressure is calculated by a moving average. 8. A method for delivering a drug solution in a syringe according to a predetermined infusion pattern, the method comprising: delivering a solution delivery pattern; setting a closing pressure lower limit value; The step of injecting the liquid medicine in the syringe by pressing the pusher of the syringe to drive the motor based on the liquid transfer pattern that has been set, and detecting that the set lower limit value of the closing pressure has been detected, is input. And a step of stopping the driving of the motor at a predetermined time after an alarm is generated based on the liquid feeding pattern. 9. The method according to claim 8, further comprising a step of detecting the volume of the syringe. 10. The liquid delivery method by a syringe pump according to claim 8, further comprising the step of setting a manufacturer name of the syringe. 11. The liquid delivery method by a syringe pump according to claim 8, further comprising the step of inputting and / or selecting a drug name. 12. The liquid delivery method using a syringe pump according to claim 8, wherein the predetermined time can be changed according to the liquid delivery pattern and / or the drug name. 13. The liquid delivery method by a syringe pump according to claim 8, wherein the closing pressure lower limit value can be arbitrarily set. 14. The liquid delivery method by a syringe pump according to claim 8, wherein the closing pressure is calculated by a moving average. 15. A computer-readable storage medium in which a control program of a liquid delivery method by a syringe pump for delivering a drug solution in a syringe according to a predetermined injection pattern is stored, and a step of inputting a liquid delivery pattern is controlled. Program code to control, the program code to control the step of setting the lower limit value of occlusion pressure, and drive control of the motor based on the input liquid transfer pattern, press the pusher of the syringe to inject the drug solution in the syringe. Controls the step of stopping the driving of the motor at a predetermined time after an alarm is generated based on the program code for controlling the step and detection that the set lower limit value of the closing pressure is lower than the set lower limit value. A program for controlling a liquid delivery method using a syringe pump is stored. Computer readable storage medium. 16. The computer-readable storage medium of claim 15, further comprising program code that controls the step of detecting the volume of the syringe. 17. The computer-readable storage medium of claim 15, further comprising program code that controls the step of setting the manufacturer name of the syringe. 18. The computer-readable storage medium of claim 15, further comprising program code that controls the step of entering and / or selecting a drug name. 19. The method according to claim 15, wherein the predetermined time further includes a program code for controlling a step that can be changed according to the liquid delivery pattern and / or the drug name. Computer readable storage medium. 20. The computer-readable storage medium according to claim 15, wherein the closing pressure lower limit value can be arbitrarily set. 21. The computer-readable storage medium according to claim 15, wherein the closing pressure is calculated by a moving average.