JP2003041414A - Clothing article having beautifully whitening effect - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a clothing article having a beautifully whitening effect of the skin. SOLUTION: This clothing article having a beautifully whitening effect is provided by the clothing article containing α-glycosyl-L-ascorbic acid and/or its derivative.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to α-glycosyl-L.
-Comprising ascorbic acid and / or its derivatives,
The present invention relates to clothing having a skin whitening effect.

[0002]

2. Description of the Related Art If the skin is irradiated with ultraviolet rays contained in sunlight, it may accelerate skin aging and cause skin cancer. In particular, in the case of humans, the amount of ultraviolet rays that directly irradiate the skin is large, and thus the skin is likely to be sunburned, because there is less hair on the body surface than in other mammals. Sunburn blackens the skin color and causes rough skin, spots, wrinkles, and the like, so it is necessary to take cosmetic measures.

As a measure against sunburn, there is a method of applying a sunburn-preventing cosmetic to a site which is easily sunburned. For example, there are cosmetics containing an ultraviolet absorber such as titanium dioxide or zinc oxide, and a whitening component such as ascorbic acid or kojic acid. In addition, there is a method of avoiding UV exposure by wearing clothing, for example, as described in JP-A-5-148734, devised to impart an ultraviolet shielding effect to the fiber structure, Further, it has been proposed to add an ultraviolet absorber such as titanium dioxide or zinc oxide. However, in the case of clothing having a thin cloth, the ultraviolet protection effect of the clothing itself can hardly be expected, and the effect cannot be expected even if such a clothing contains an ultraviolet absorber. Further, it is difficult to apply the sunscreen agent directly to the skin surface to which clothes are usually worn, because it is difficult to do in public and the application area is large, which is very troublesome and impractical.

[0004]

SUMMARY OF THE INVENTION An object of the present invention is to provide a garment, particularly a garment made of a thin cloth, which has a whitening effect.

[0005]

Means for Solving the Problems The inventors of the present invention conducted extensive research and searched for α, which is a derivative of ascorbic acid.
-When glycosyl-L-ascorbic acid and / or its derivative is contained in clothing and worn, when it comes into contact with the skin, α-glycosyl-L-ascorbic acid is partially released from the clothing, which is transdermally absorbed. By converting it into L-ascorbic acid by an enzyme such as α-glycosidase in the body, it exerts a whitening effect on the skin just as when applying ascorbic acid directly to the skin, and blackening the skin color due to sunburn etc. Found to prevent. Also, since the effect of narrative can be given for a certain period,
It was confirmed that the time and effort to apply ascorbic acid directly to the skin could be significantly reduced.

That is, the present invention solves the above problems by α-
The solution is to provide a garment comprising glycosyl-L-ascorbic acid and its derivatives.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION α-Glycosyl-L according to the present invention
-Ascorbic acid and / or a derivative thereof is one in which one or more molecules of D-glucose are bonded to one molecule of L-ascorbic acid and / or a derivative thereof, for example, 2
Examples thereof include -O-α-D-glucopyranosyl-L-ascorbic acid and acylated derivatives thereof, and these compounds are
The stability of heat and acid is extremely superior to that of conventional L-ascorbic acid. 2-O-α-D-glucopyranosyl-L-
As a method for producing ascorbic acid, for example, JP-A-3
The methods disclosed in JP-A-139288, JP-A-3-183492 and JP-A-3-135992 can be exemplified. A method for producing the acylated derivative is disclosed in JP-A No. 11-286497, and the 2-O-α-D-glucopyranosyl-L-ascorbic acid and the derivative thereof, and further their sodium salts. , Potassium salts and the like can be used in the present invention. The above-mentioned publication discloses that α-glycosyl-L-ascorbic acid and its derivatives have a whitening effect on the skin like L-ascorbic acid. The α-glycosyl-L-ascorbic acid and / or its derivative used in the clothing of the present invention is 2-O- in which one D-glucose is bonded to the 2-position hydroxyl group of L-ascorbic acid. α-D-Glucopyranosyl-L-ascorbic acid (trade name “AA-2G” sold by Hayashibara Shoji Co., Ltd.)
Is particularly preferably used in the present invention because it has excellent stability and is easily available because it is commercially available.

In the garment of the present invention, usually, one or more kinds of a-glycosyl-L-ascorbic acid and / or its derivative are used together with a carrier material for supporting them on the garment. To be done. The carrier is usually composed mainly of an inorganic polymer substance and / or an organic polymer substance, and as the individual inorganic polymer substance, for example, glass,
Ceramics, silanes, polysiloxanes, polyorganosiloxanes, silicone oils and the like, and organic polymer substances such as polyester, polyamide, polycarbonate, polystyrene, polypropylene, polyethylene, polymethylpentene, polysulfone. , Poly-
Tersulfone, polyarylate, polyetherimide,
Polymethylmethacrylate, polyolefin, acrylic, nylon, acetate, bemberg, rayon, cotton, hemp, wool, silk, cellulose, cellulose ester,
Synthetic resins such as pullulan, starch, amyloses, amylopectin, semi-synthetic resins, regenerated resins, natural resins, and
Examples thereof include a mixture of these materials such as mixing, kneading, kneading, knitting, knitting, knitting, and laminating. If desired, these carrier materials may be in a liquid, solid or semi-solid state, and their shapes are, for example, powders, granules, beads, films and sheets.
Fibers, threads, cotton, woven fabrics, non-woven fabrics, etc., or a mixture thereof. Α-Glycosyl-L is added to such a carrier.
-In supporting ascorbic acid and / or its derivative, if necessary, for example, a general-purpose solvent, a microencapsulating agent, a binder, a monomer, an oligomer,
A neutralizing agent, a polyfunctional reagent, a sizing agent, an adhesive, a propellant, a surfactant and the like can be used.

The clothing of the present invention preferably contains an ultraviolet ray shielding agent in addition to the above α-glycosyl-L-ascorbic acid and / or its derivative. As the ultraviolet shielding agent, any substance that has an ultraviolet absorbing property or an ultraviolet scattering property and is acceptable as a skin external preparation can be used without particular limitation. In particular, 2-hydroxy-4-
Methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, 2-hydroxy-
Sodium 4-methoxybenzophenone-5-sulfonate, dihydroxydimethoxybenzophenone, sodium dihydroxydimethoxybenzophenonesulfonate,
Benzophenone derivatives such as 2,4-dihydroxybenzophenone and tetrahydroxybenzophenone, paraaminobenzoic acid, ethyl paraaminobenzoate, glyceryl paraaminobenzoate, amyl paradimethylaminobenzoate, octyl paradimethylaminobenzoate, and other paraaminobenzoic acid derivatives, paramethoxy. Ethyl cinnamate, isopropyl paramethoxycinnamate, octyl paramethoxycinnamate, 2-ethoxyethyl paramethoxycinnamate, sodium paramethoxycinnamate, potassium paramethoxycinnamate,
Methylcinnamic acid derivatives such as glyceryl mono-2-ethylhexanoate diparamethoxycinnamate, octyl salicylate, phenyl salicylate, homomenthyl salicylate, dipropylene glycol salicylate, ethylene glycol salicylate, salicylic acid derivatives such as myristyl salicylate and methyl salicylate, Urocanic acid, urocanic acid derivatives such as ethyl urocanate, 4-tert-butyl-
Organic UV rays such as dibenzoylmethane derivatives such as 4'-methoxydibenzoylmethane, benzotriazole derivatives such as 2- (2'-hydroxy-5'-methylphenyl) benzotriazole, and anthranilic acid derivatives such as methyl anthranilate Absorbents, titanium oxide, zinc oxide and the like are preferred.

In the garment of the present invention, as a blending component other than α-glycosyl-L-ascorbic acid and / or its derivative and a carrier material, for example, maltose, trehalo, etc., within a range not departing from the object of the present invention. -Su, Pullulan,
Sugars such as starch, photosensitizers such as Photosensitizer No. 101, Photosensitizer No. 201, Photosensitizer No. 301, and Photosensitizer No. 401, cyanine-based, merocyanine-based, rhodacyanine-based, oxanol-based, styryl-based, -Dyes such as styryl, L-
Ascorbic acid, vitamins other than L-ascorbic acid, infrared absorbers, flame retardants, wrinkle removers, deodorants, water repellents, oil repellents, antistatic agents, conductive agents, water absorbing agents, moisture proofing agents, aromatic agents, Antioxidants, insect repellents, antifungal agents, antibacterial agents, antiallergic agents, blood circulation promoters such as α-glycosyl rutin and α-glycosyl hesperidin, surfactants, emulsion stabilizers, chelating agents, etc. are appropriately used. be able to.

As the clothing of the present invention, a clothing of a thin cloth which is extremely transparent to ultraviolet rays is effective. In particular, panty-stockings and other stockings have extremely thin fabrics and are in close contact with the skin. Therefore, α-glycosyl-L-ascorbic acid and / or its derivatives are removed from the fabric by moisture, sweat, sebum, etc. It is easily released and percutaneously absorbed, maximizing the whitening effect. When the clothing of the present invention is applied to clothing such as stockings which adheres to the skin, α-glycosyl-L-ascorbic acid and / or its derivative is applied, sprayed or dipped on the surface of the side in contact with the skin. Adhesion is preferable because the effects of the present invention can be sufficiently exhibited.

Other than the above-mentioned clothing, it can be applied as the clothing of the present invention. For example, business suits, saxophone suits, three-piece arrangements, blazers, cardigan jackets, jackets and vests such as blouson, bolero, sack, shirts, dress shirts, formal shirts, and sportswear. Shirts such as t-shirts, aloha shirts, cutter shirts, open-collar shirts, polo shirts, tee shirts, slacks, Rappa trousers, Nikka-Bokka-,
Gaucho pants, pedal pushers, jeans and other sponges, ties, bow ties, cravats, tie ties, windsor ties and other ties, undershirts, bluffs, looses, scanties -, Show
T-shirts, trunks and other underwear, Langerie, Pettico-
Foundations such as toys, camisoles, brassieres, girdles, bodysuits, blouses such as choli, midi blouse, set-in blouse, divided skirts, midi skirts, miniskirts -Skirts such as skirts, trumpet skirts, lap skirts, apron dresses, basic dresses, camisole dresses, skirt dresses, coat dresses, house dresses,
Dresses such as jumper dresses, sack dresses, sheath dresses, shift dresses, pullovers, cardigans, boat necks, balkeys, crows
Neck-seater, turtleneck, etc., Balmacon, duffle coat, duster coat, inverness, raglan, trench coat, lane coat and other outerwear, tailcoat, Formal clothing such as taxi, ten-gallon hat, beret, rimless hat, alpine, boat,
Busby, Davy, Fedora, Fes, Hunting Cap, Opera Hat, Sombrero, Breton, Cloche, Pillbox, Picture Hat, Snood, Tamoshanta, Talk, Urban, Hats such as bonnets, caskets, full face caps, uncle socks, bobby socks, clue socks, two socks, over two socks, sweat socks, three quarter socks, tube socks, etc. Socks, and even anoraks, towels, towelettes, bath towels,
Handkerchief, hand towel, fur, gloves, arm cover, mittens, muffler, scarf, ribbon, belly band, uniform, jar
In addition to general clothing such as jersey, Japanese clothing, swimwear, wetsuits, leotards, workwear, fire fighting clothing, military clothing, flight clothing, diving clothing, spacesuits, interlinings and linings for preparing those clothing. Includes all clothing materials.

The clothing of the present invention contains α-glycosyl-L-ascorbic acid and / or a derivative thereof,
Conventional mixing, coating, spraying, dipping, fixing, etc. may be applied depending on the shape, size, purpose of use, etc. of the clothing. To allow the clothing of the present invention to carry α-glycosyl-L-ascorbic acid and / or its derivative temporarily or for a short period of time, for example, one or more of α-glycosyl-L-ascorbic acid and / or its derivative can be used. , If necessary, supporting material, microencapsulating agent, binder, monomer, oligomer, polyfunctional reagent, sizing agent, adhesive, coloring agent, flame retardant, wrinkle remover, deodorant, water repellent , Oil repellent, antistatic agent, conductive agent, water absorbing agent, moistureproof agent, fragrance, antioxidant,
One or more of insect repellents, fungicides, antibacterial agents, antiallergic agents, blood circulation promoters, surfactants, emulsion stabilizers, chelating agents and the like, together with, for example, water, pentane, hexane, cyclohexane, petroleum ether. -Ter, petroleum benzine, isooctane, octane, benzene, toluene, xylene, carbon tetrachloride, chloroform, 1,2-dichloroethane, trichloroethylene, tetrachloroethylene, chlorobenzene, bromobenzene, dichlorobenzene, methanol,
Ethanol, 1-propanol, 2-propanol,
2,2,2-trifluoroethanol, 1-butano-
, 2-butanol, isobutyl alcohol, isopentyl alcohol, cyclohexanol, ethylene glycol, propylene glycol, 2-methoxyethanol
1, 2-ethoxyethanol, phenol, benzyl alcohol, cresol, diethylene glycol, triethylene glycol, glycerin, diethyl ether, diisopropyl ether, tetrahydrofuran, tetrahydropyran, 1, 4-dioxane, anisole, 1,2
-Dimethoxyethane, diethylene glycol dimethyl ether, dicyclohexyl-18-crown-6, methyl carbitol, ethyl carbitol, furfural,
Acetone, methyl ethyl ketone, cyclohexanone, formic acid, acetic acid, acetic anhydride, trichloroacetic acid, trifluoroacetic acid, ethyl acetate, butyl acetate, ethylene carbonate, propylene carbonate, formamide, N-methylformamide, N,
N-dimethylformamide, N-methylacetamide,
N, N-dimethylacetamide, N-methylpyrrolidone, hexamethylphosphoric triamide, triethyl phosphate, acetonitrile, propionitrile, succinonitrile,
Dissolve or suspend in a general-purpose solvent such as benzonitrile, nitromethane, nitrobenzene, ethylenediamine, pyridine, piperidine, morpholine, dimethylsulfoxide, sulfolane or a mixed solution thereof, and, if necessary, store in a closed container together with a general-purpose propellant. . The solution and suspension thus obtained are applied to or sprayed on the surface of the clothing constituent material, or by dipping the clothing constituent material in these to whiten a desired part or the whole of the clothing material. The effect can be imparted. When α-glycosyl-L-ascorbic acid and / or a derivative thereof is attached to the clothing of the present invention so that it can be easily removed by washing or washing, for example, in addition to normal outing and athletics. Before going out to places exposed to strong ultraviolet rays such as, gardening, picnic, hiking, trekking, mountaineering, swimming, skiing, golf, cycling, shellfishing, fishing, etc., after temporarily treating clothing, after wearing, If necessary, by washing or washing, α-glycosyl-L-ascorbic acid and / or
Alternatively, the derivative thereof can be easily desorbed.

To allow the clothing of the present invention to carry α-glycosyl-L-ascorbic acid and / or its derivative for a long period of time, one or more α-glycosyl-L-ascorbic acid and / or its derivative may be left as they are. State, or, for example, silica, activated carbon, melamine resin, acrylate resin, urea resin, etc. having a fine porous structure, which are microencapsulated using urethane resin, acrylic resin, aminoplast resin , Epoxy resin, glyoxal resin, ethylene urea resin, silicone resin and other binders, if necessary,
Disperse in an aqueous medium containing a higher alcohol or a surfactant. Soak the cloth or sewn product in this dispersion and remove the excess dispersion by centrifugation etc.
After drying at a temperature of not higher than 140.degree. C., preferably at a temperature of not higher than 140.degree. According to this method, the clothes can be loaded with α-glycosyl-L-ascorbic acid and / or its derivative used in the present invention for a long period of time, and the washing resistance is also improved. When the α-glycosyl-L-ascorbic acid and / or its derivative used in the present invention is contained, α-glycosyl- may be added to the clothing article of the present invention at an appropriate step after or until the preparation of the clothing article is completed. L-ascorbic acid and / or its derivative may be contained in an appropriate amount.

The amount of α-glycosyl-L-ascorbic acid and / or its derivative used in the present invention for clothing is as follows: α-glycosyl-L-ascorbic acid and / or
Or, depending on the kind of the derivative, the kind of the clothing, and the thickness of the cloth of the clothing, it is usually 0 in terms of the weight of the α-glycosyl-L-ascorbic acid and / or the derivative thereof. 0.0001% to 10%, preferably 0.0
01% to 10%. If the content is less than 0.0001%, the action and effect of the present invention will not be sufficiently exerted, and 10%
Even if it is contained in the above amount, it is not economical because it does not exhibit the effect for the content.

Embodiments of the present invention will be described below based on examples.

[0017]

Example 1 <Stocking> 2-O-α-D-glucopyranosyl-L-ascorbic acid (trade name "AA-2
G ”Hayashibara Shoji Co., Ltd.) 1 part by weight was added to 100 parts by weight of N-methylpyrrolidone, and then silica particles (particle size 2 to 6 μm) having a fine porous structure were immersed in a solution according to a conventional method. Microencapsulated.

2-O-α-D-glucopyranosyl-L-
The microcapsules containing ascorbic acid were mixed with an acrylic ester-based binder (trade name "Brymar H
A-16 ”, manufactured by Reichhold Japan) with a weight ratio of 1: 1
After mixing at a ratio of, a 120 g / l aqueous dispersion was prepared.
A stocking made of nylon 6 textured yarn is dipped in this dispersion liquid, 3% of the dry weight of microcapsules is attached, dehydrated by a centrifugal dehydrator, and dried at 120 ° C.
Dry heat setting was performed at 40 ° C. for 3 minutes. After that, 2-O-α-
A stocking with microcapsules of D-glucosyl-L-ascorbic acid attached to the right leg, 2-O-α-
Stockings to which D-glucopyranosyl-L-ascorbic acid was not attached were placed on the left leg portions and hand-sewn to produce stockings.

Distribute 5 pairs of this stocking to 20 women aged 15 to 40, and be sure to wear it together with the skirt when going out. After wearing, each person should wash and re-wear. Under the condition, a trial test was conducted for one month. As a result, the skin color of the right leg was significantly whiter than that of the left leg. In addition, when asked about the findings on the questionnaire, most of them answered that the skin whitening effect was sufficiently exhibited even after washing several times. 2
A trial test was conducted in the same manner using a stocking prepared in the same manner by using L-ascorbic acid instead of -O-α-D-glucopyranosyl-L-ascorbic acid,
It had no effect.

[0020]

[Example 2] <Sunscreen gloves> In the same manner as in Example 1, 70 parts by weight of microcapsules of polyetherester block copolymer (trade name "SR-1000", manufactured by Takamatsu Oil & Fats Co., Ltd.) and melamine fiber processing resin were used. (Product name: Sumitex Resin, manufactured by Sumitomo Chemical Co., Ltd.) 30 parts by weight of a mixed binder in a weight ratio of 1:
After mixing at a ratio of 1, an aqueous dispersion of 100 g / l was prepared.

A cotton sunshade for the right arm (long type up to the elbow) was dipped in this dispersion liquid, and 4.5% of the dry weight of microcapsules was adhered to it.
Wet heat setting was performed at 0 ° C. for 3 minutes. The sunshade gloves for the left arm were untreated and served as a control.

A woman 15 to 40 years old wearing this sunshade glove 2
A trial test was carried out for 1 month under the condition that 0 people were always worn when going out or driving. As a result, the skin color of the right arm was significantly whiter than that of the left arm. In addition, when asked about the findings on the questionnaire, most of them answered that the skin whitening effect was sufficiently exhibited even after washing several times. When a trial test was conducted in the same manner using a glove made in the same manner by using L-ascorbic acid instead of 2-O-α-D-glucopyranosyl-L-ascorbic acid, no effect was obtained at all.

[0023]

Industrial Applicability As described above, the present invention has a whitening effect on the skin of a garment in which α-glycosyl-L-ascorbic acid and / or its derivative is contained in the garment. Further, since the whitening effect is exhibited only by wearing, it is possible to omit the troublesome work of applying the external whitening agent to the skin, and it can be used as a clothing article having a whitening effect for a long period of time. The garment of the present invention is very useful especially for clothes, such as stockings, which are made of thin cloth and are in contact with the skin.

It can be said that the present invention, which has such remarkable effects, is a significantly significant invention that contributes to the field.

Front page continuation (51) Int.Cl. ⁷ Identification code FI theme code (reference) A41B 11/00 A41B 11/00 Z 17/00 17/00 Z A41D 1/00 A41D 1/00 C D06M 13/127 D06M 13/127 13/188 13/188 23/12 23/12 F term (reference) 3B018 AC00 AD07 3B029 HA01 HA03 HB00 3B030 AA01 AB00 4L031 AA20 AB36 4L033 AA08 AB09 AC10 AC15 BA09 BA17

Claims (4)

[Claims] 1. A clothing article comprising α-glycosyl-L-ascorbic acid and / or a derivative thereof. 2. The garment according to claim 1, which comprises one or more UV-screening agents together with α-glycosyl-L-ascorbic acid and / or a derivative thereof. 3. The garment according to claim 1, wherein α-glycosyl-L-ascorbic acid and / or its derivative is attached to the surface of the garment constituent material. 4. The article of clothing is stockings.
The clothing according to any one of 1 to 3.