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ITUB20160256A1 - ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN - Google Patents

ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN

Info

Publication number
ITUB20160256A1
ITUB20160256A1 ITUB2016A000256A ITUB20160256A ITUB20160256A1 IT UB20160256 A1 ITUB20160256 A1 IT UB20160256A1 IT UB2016A000256 A ITUB2016A000256 A IT UB2016A000256A IT UB20160256 A ITUB20160256 A IT UB20160256A IT UB20160256 A1 ITUB20160256 A1 IT UB20160256A1
Authority
IT
Italy
Prior art keywords
tolvaptan
persons
synthesis
derivatives
esterified water
Prior art date
Application number
ITUB2016A000256A
Other languages
Italian (it)
Inventor
Samuele Frigoli
Davide Longoni
Marco Alpegiani
Original Assignee
Olon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olon Spa filed Critical Olon Spa
Priority to ITUB2016A000256A priority Critical patent/ITUB20160256A1/en
Publication of ITUB20160256A1 publication Critical patent/ITUB20160256A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
ITUB2016A000256A 2016-01-15 2016-01-15 ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN ITUB20160256A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ITUB2016A000256A ITUB20160256A1 (en) 2016-01-15 2016-01-15 ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUB2016A000256A ITUB20160256A1 (en) 2016-01-15 2016-01-15 ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN

Publications (1)

Publication Number Publication Date
ITUB20160256A1 true ITUB20160256A1 (en) 2017-07-15

Family

ID=55860965

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUB2016A000256A ITUB20160256A1 (en) 2016-01-15 2016-01-15 ESTERIFIED WATER-BASED HYDRO-PERSONS DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF TOLVAPTAN

Country Status (1)

Country Link
IT (1) ITUB20160256A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2867187A1 (en) * 2004-03-02 2005-09-09 Centre Nat Rech Scient New benzoazepine derivatives are V2 arginine vasopressin receptors Antagonist, useful for treating cardiac disease
WO2007026971A2 (en) * 2005-09-02 2007-03-08 Otsuka Pharmaceutical Co., Ltd. Process for preparing benzazepine compounds or salts thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2867187A1 (en) * 2004-03-02 2005-09-09 Centre Nat Rech Scient New benzoazepine derivatives are V2 arginine vasopressin receptors Antagonist, useful for treating cardiac disease
WO2007026971A2 (en) * 2005-09-02 2007-03-08 Otsuka Pharmaceutical Co., Ltd. Process for preparing benzazepine compounds or salts thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CORDERO-VARGAS A ET AL: "A flexible approach for the preparation of substituted benzazepines: Application to the synthesis of tolvaptan", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB, vol. 14, no. 18, 15 September 2006 (2006-09-15), pages 6165 - 6173, XP027992895, ISSN: 0968-0896, [retrieved on 20060915] *

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