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ITRM920028A1 - Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica. - Google Patents

Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.

Info

Publication number
ITRM920028A1
ITRM920028A1 IT000028A ITRM920028A ITRM920028A1 IT RM920028 A1 ITRM920028 A1 IT RM920028A1 IT 000028 A IT000028 A IT 000028A IT RM920028 A ITRM920028 A IT RM920028A IT RM920028 A1 ITRM920028 A1 IT RM920028A1
Authority
IT
Italy
Prior art keywords
pharmaceutical compositions
acil
compositions containing
long chain
aliphatic alcohols
Prior art date
Application number
IT000028A
Other languages
English (en)
Inventor
Piero Foresta
Domenico Misiti
Mose Santaniello
Maria Ornella Tinti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ITRM920028A0 publication Critical patent/ITRM920028A0/it
Priority to ITRM920028A priority Critical patent/IT1254136B/it
Priority to ZA93161A priority patent/ZA93161B/xx
Priority to CA002087084A priority patent/CA2087084C/en
Priority to JP00475793A priority patent/JP3294652B2/ja
Priority to DE69309725T priority patent/DE69309725T2/de
Priority to AT93830010T priority patent/ATE151744T1/de
Priority to DK93830010.0T priority patent/DK0552138T3/da
Priority to EP93830010A priority patent/EP0552138B1/en
Priority to ES93830010T priority patent/ES2101998T3/es
Priority to KR1019930000523A priority patent/KR100251887B1/ko
Publication of ITRM920028A1 publication Critical patent/ITRM920028A1/it
Priority to US08/250,108 priority patent/US5519056A/en
Priority to US08/409,714 priority patent/US5525627A/en
Application granted granted Critical
Publication of IT1254136B publication Critical patent/IT1254136B/it
Priority to GR960403681T priority patent/GR3023163T3/el
Priority to HK98104939A priority patent/HK1005864A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
ITRM920028A 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica. IT1254136B (it)

Priority Applications (14)

Application Number Priority Date Filing Date Title
ITRM920028A IT1254136B (it) 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.
ZA93161A ZA93161B (en) 1992-01-16 1993-01-11 Esters of acyl carnitines with long-chain alpihatic alcohols and pharmaceutical compositions containing same having antibacterial activity
CA002087084A CA2087084C (en) 1992-01-16 1993-01-11 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antimycotic activity
JP00475793A JP3294652B2 (ja) 1992-01-16 1993-01-14 アシルカルニチンエステル類および抗真菌活性医薬組成物
DK93830010.0T DK0552138T3 (da) 1992-01-16 1993-01-15 Anvendelse af estere af acylcarnitiner med langkædede alifatiske alkoholer til fremstilling af farmaceutiske præparater med antimykotisk aktivitet.
AT93830010T ATE151744T1 (de) 1992-01-16 1993-01-15 Verwendung von estern des acyl-carnitins mit langkettigen aliphatischen alkoholen zur herstellung von pharmazeutischen zusammensetzungen mit antimykotischer wirkung
DE69309725T DE69309725T2 (de) 1992-01-16 1993-01-15 Verwendung von Estern des Acyl-Carnitins mit langkettigen aliphatischen Alkoholen zur Herstellung von pharmazeutischen Zusammensetzungen mit antimykotischer Wirkung
EP93830010A EP0552138B1 (en) 1992-01-16 1993-01-15 Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity
ES93830010T ES2101998T3 (es) 1992-01-16 1993-01-15 Uso de esteres de acilcarnitinas con alcoholes alifaticos de cadena larga para la preparacion de composiciones farmaceuticas con actividad antimicotica.
KR1019930000523A KR100251887B1 (ko) 1992-01-16 1993-01-16 긴 사슬의 지방족 알콜을 가진 아실카르니틴 에스테르와 항진균 활성을 지닌 그의 약제조성물
US08/250,108 US5519056A (en) 1992-01-16 1994-05-26 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antimycotic activity
US08/409,714 US5525627A (en) 1992-01-16 1995-03-24 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antimycotic activity
GR960403681T GR3023163T3 (en) 1992-01-16 1997-04-17 Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity
HK98104939A HK1005864A1 (en) 1992-01-16 1998-06-05 Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920028A IT1254136B (it) 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.

Publications (3)

Publication Number Publication Date
ITRM920028A0 ITRM920028A0 (it) 1992-01-16
ITRM920028A1 true ITRM920028A1 (it) 1993-07-16
IT1254136B IT1254136B (it) 1995-09-08

Family

ID=11400574

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920028A IT1254136B (it) 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.

Country Status (13)

Country Link
US (2) US5519056A (it)
EP (1) EP0552138B1 (it)
JP (1) JP3294652B2 (it)
KR (1) KR100251887B1 (it)
AT (1) ATE151744T1 (it)
CA (1) CA2087084C (it)
DE (1) DE69309725T2 (it)
DK (1) DK0552138T3 (it)
ES (1) ES2101998T3 (it)
GR (1) GR3023163T3 (it)
HK (1) HK1005864A1 (it)
IT (1) IT1254136B (it)
ZA (1) ZA93161B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1258370B (it) * 1992-03-02 1996-02-26 Sigma Tau Ind Farmaceuti Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono.
IT1261828B (it) * 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
US5741816A (en) * 1994-06-20 1998-04-21 Tanabe Seiyaku Co., Ltd. Hair-growth agent
IT1277898B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1283955B1 (it) * 1996-03-20 1998-05-07 Sigma Tau Ind Farmaceuti Bis alcanoil esteri della carnitina ad attivita' antibatterica, antimicotica ed antiprotozoaria.
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588443A5 (it) * 1974-09-25 1977-06-15 Lonza Ag
CH596147A5 (it) * 1974-09-25 1978-02-28 Lonza Ag
IT1116037B (it) * 1979-04-23 1986-02-10 Sigma Tau Ind Farmaceuti Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico
IT1147079B (it) * 1980-05-30 1986-11-19 Sigma Tau Ind Farmacuetiche Ri Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono
IT1170861B (it) * 1981-03-31 1987-06-03 Sigma Tau Ind Farmaceuti Ester di mercaptoacil-carnitine procedimento per la loro preparazione e loro uso terapeutico
IT1191945B (it) * 1986-06-04 1988-03-31 Avantgarde Spa N-alchilammidi della d(+)-carnitina dotate di attivita' antibatterica,procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1235494B (it) * 1987-12-02 1992-09-04 Avantgarde Spa N-alchilammidi della dl e l(-)carnitina dotate di attivita' antibatterica, procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
IT1231944B (it) * 1989-05-05 1992-01-16 Sigma Tau Ind Farmaceuti Composizione farmaceutica per il trattamento di protozoosi, particolarmente della tripasonomiasi comprendente d-carnitina o un alcanoilderivato della d-carnitina
IT1240775B (it) * 1990-02-23 1993-12-17 Sigma Tau Ind Farmaceuti Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma.

Also Published As

Publication number Publication date
KR100251887B1 (ko) 2000-05-01
DE69309725D1 (de) 1997-05-22
US5525627A (en) 1996-06-11
CA2087084A1 (en) 1993-07-17
DK0552138T3 (da) 1997-10-20
ITRM920028A0 (it) 1992-01-16
HK1005864A1 (en) 1999-01-29
CA2087084C (en) 2003-12-23
GR3023163T3 (en) 1997-07-30
JP3294652B2 (ja) 2002-06-24
IT1254136B (it) 1995-09-08
EP0552138A2 (en) 1993-07-21
KR930016392A (ko) 1993-08-26
ES2101998T3 (es) 1997-07-16
EP0552138B1 (en) 1997-04-16
ATE151744T1 (de) 1997-05-15
US5519056A (en) 1996-05-21
DE69309725T2 (de) 1997-07-31
EP0552138A3 (en) 1993-10-20
ZA93161B (en) 1993-10-06
JPH05339219A (ja) 1993-12-21

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