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IT8820361A0 - Procedimento ed intermedi per preparare proline 4_sostituite. - Google Patents

Procedimento ed intermedi per preparare proline 4_sostituite.

Info

Publication number
IT8820361A0
IT8820361A0 IT8820361A IT2036188A IT8820361A0 IT 8820361 A0 IT8820361 A0 IT 8820361A0 IT 8820361 A IT8820361 A IT 8820361A IT 2036188 A IT2036188 A IT 2036188A IT 8820361 A0 IT8820361 A0 IT 8820361A0
Authority
IT
Italy
Prior art keywords
sustituite
procedure
proline
preparing
preparing proline
Prior art date
Application number
IT8820361A
Other languages
English (en)
Other versions
IT1217443B (it
Inventor
John Kurian Thottathil
Original Assignee
E R Squibb & Cons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/044,691 external-priority patent/US4734508A/en
Application filed by E R Squibb & Cons Inc filed Critical E R Squibb & Cons Inc
Publication of IT8820361A0 publication Critical patent/IT8820361A0/it
Application granted granted Critical
Publication of IT1217443B publication Critical patent/IT1217443B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT20361/88A 1987-05-01 1988-04-28 Procedimento ed intermedi per preparare proline 4-sostituite IT1217443B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/044,691 US4734508A (en) 1987-05-01 1987-05-01 Process and intermediates for preparing 4-substituted proline derivatives
US07/092,360 US4851514A (en) 1987-05-01 1987-09-02 Process for preparing a compound useful in preparing ace inhibitors and intermediate produced thereby

Publications (2)

Publication Number Publication Date
IT8820361A0 true IT8820361A0 (it) 1988-04-28
IT1217443B IT1217443B (it) 1990-03-22

Family

ID=26721884

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20361/88A IT1217443B (it) 1987-05-01 1988-04-28 Procedimento ed intermedi per preparare proline 4-sostituite

Country Status (6)

Country Link
US (1) US4851514A (it)
CA (1) CA1328272C (it)
FR (2) FR2618776B1 (it)
GB (3) GB2204585B (it)
IE (1) IE61532B1 (it)
IT (1) IT1217443B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1268418B1 (en) * 2000-03-27 2006-06-14 Applied Research Systems ARS Holding N.V. Pharmaceutically active pyrrolidine derivatives as bax inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291040A (en) * 1979-10-22 1981-09-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines
US4316905A (en) * 1980-07-01 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of various 4-substituted prolines
US4337201A (en) * 1980-12-04 1982-06-29 E. R. Squibb & Sons, Inc. Phosphinylalkanoyl substituted prolines
US4501901A (en) * 1983-09-19 1985-02-26 E. R. Squibb & Sons, Inc. Method for making substituted prolines
US4492655A (en) * 1984-04-27 1985-01-08 Rhone-Poulenc, Inc. Tricyclopentadienyl cerium and process for preparing the same
US4588819A (en) * 1984-11-19 1986-05-13 E. R. Squibb & Sons, Inc. Process and intermediates for preparing trans-4-substituted-s-prolines

Also Published As

Publication number Publication date
FR2626574A1 (fr) 1989-08-04
FR2618776A1 (fr) 1989-02-03
US4851514A (en) 1989-07-25
GB2235452A (en) 1991-03-06
GB8810182D0 (en) 1988-06-02
IE61532B1 (en) 1994-11-16
FR2618776B1 (fr) 1994-08-12
FR2626574B1 (fr) 1990-12-14
GB2235453A (en) 1991-03-06
GB2235453B (en) 1991-09-04
GB2204585A (en) 1988-11-16
GB9020681D0 (en) 1990-11-07
CA1328272C (en) 1994-04-05
IT1217443B (it) 1990-03-22
GB9020682D0 (en) 1990-11-07
GB2204585B (en) 1991-09-04
IE881277L (en) 1988-11-01

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970429