IT8249418A0 - Derivati dell'ergolina, loro preparazione e medicamenti contenenti questi derivati - Google Patents

Derivati dell'ergolina, loro preparazione e medicamenti contenenti questi derivati

Info

Publication number: IT8249418A0
Authority: IT; Italy
Prior art keywords: derivatives; preparation; ergoline; medicines containing; medicines
Prior art date: 1981-11-04

Application number

IT8249418A

Other languages

English (en)

Other versions

IT1189409B (it

Inventor

Ziegler Rene

Stutz Peter

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-11-04

Filing date

1982-11-03

Publication date

1982-11-03

1982-11-03 Application filed by Sandoz Ag filed Critical Sandoz Ag

1982-11-03 Publication of IT8249418A0 publication Critical patent/IT8249418A0/it

1988-02-04 Application granted granted Critical

1988-02-04 Publication of IT1189409B publication Critical patent/IT1189409B/it

Links

AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IT49418/82A 1981-11-04 1982-11-03 Derivati dell'ergolina,loro preparazione e medicamenti contenenti questi derivati IT1189409B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH7056/81A CH653333A5 (de)	1981-11-04	1981-11-04	N-substituierte ergolin- und 9,10-didehydroergolinderivate, ihre herstellung und sie enthaltende arzneimittel.

Publications (2)

Publication Number	Publication Date
IT8249418A0 true IT8249418A0 (it)	1982-11-03
IT1189409B IT1189409B (it)	1988-02-04

Family

ID=4319237

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT49418/82A IT1189409B (it)	1981-11-04	1982-11-03	Derivati dell'ergolina,loro preparazione e medicamenti contenenti questi derivati

Country Status (27)

Country	Link
US (1)	US4783464A (it)
JP (1)	JPS5885885A (it)
AT (1)	AT382374B (it)
AU (1)	AU561250B2 (it)
BE (1)	BE894844A (it)
CA (1)	CA1193249A (it)
CH (1)	CH653333A5 (it)
CY (1)	CY1421A (it)
DE (1)	DE3239788A1 (it)
DK (1)	DK486582A (it)
ES (1)	ES8403898A1 (it)
FI (1)	FI71735C (it)
FR (1)	FR2516084A1 (it)
GB (1)	GB2108502B (it)
HK (1)	HK37188A (it)
HU (1)	HU187798B (it)
IE (1)	IE54122B1 (it)
IL (1)	IL67156A (it)
IT (1)	IT1189409B (it)
KE (1)	KE3797A (it)
MY (1)	MY8600310A (it)
NL (1)	NL8204213A (it)
NZ (1)	NZ202363A (it)
PH (1)	PH20595A (it)
PT (1)	PT75773A (it)
SE (1)	SE450122B (it)
ZA (1)	ZA828104B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4902691A (en) *	1988-12-19	1990-02-20	Eli Lilly And Company	Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3957785A (en) *	1971-12-02	1976-05-18	Societa' Farmaceutici Italia S.P.A.	Bβ-Pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives
BE792515A (fr) *	1971-12-10	1973-06-08	Sandoz Sa	Nouveaux derives de l'acide lysergique, leur preparation et leur application comme medicaments
HU172649B (hu) *	1975-04-24	1978-11-28	Gyogyszerkutato Intezet	Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
GB1549829A (en) *	1976-05-26	1979-08-08	Farmaceutici Italia	10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
GB1555751A (en) *	1977-02-02	1979-11-14	Farmaceutici Italia	Ergoline deritatives
AU553809B2 (en) *	1981-07-21	1986-07-31	Farmitalia Carlo Erba S.P.A.	Ergoline derivatives

1981
- 1981-11-04 CH CH7056/81A patent/CH653333A5/de not_active IP Right Cessation
1982
- 1982-10-27 DE DE19823239788 patent/DE3239788A1/de not_active Withdrawn
- 1982-10-27 FR FR8218136A patent/FR2516084A1/fr active Granted
- 1982-10-28 BE BE1/10627A patent/BE894844A/fr not_active IP Right Cessation
- 1982-10-28 FI FI823694A patent/FI71735C/fi not_active IP Right Cessation
- 1982-10-29 PH PH28072A patent/PH20595A/en unknown
- 1982-11-01 NL NL8204213A patent/NL8204213A/nl not_active Application Discontinuation
- 1982-11-01 GB GB08231203A patent/GB2108502B/en not_active Expired
- 1982-11-02 CA CA000414701A patent/CA1193249A/en not_active Expired
- 1982-11-02 NZ NZ202363A patent/NZ202363A/en unknown
- 1982-11-02 DK DK486582A patent/DK486582A/da unknown
- 1982-11-02 IL IL67156A patent/IL67156A/xx unknown
- 1982-11-02 PT PT75773A patent/PT75773A/pt unknown
- 1982-11-02 SE SE8206217A patent/SE450122B/sv not_active IP Right Cessation
- 1982-11-02 JP JP57191947A patent/JPS5885885A/ja active Granted
- 1982-11-03 AT AT0400482A patent/AT382374B/de not_active IP Right Cessation
- 1982-11-03 IE IE2627/82A patent/IE54122B1/en unknown
- 1982-11-03 AU AU90107/82A patent/AU561250B2/en not_active Ceased
- 1982-11-03 ES ES517082A patent/ES8403898A1/es not_active Expired
- 1982-11-03 IT IT49418/82A patent/IT1189409B/it active
- 1982-11-03 HU HU823525A patent/HU187798B/hu not_active IP Right Cessation
- 1982-11-04 ZA ZA828104A patent/ZA828104B/xx unknown
1986
- 1986-12-30 MY MY310/86A patent/MY8600310A/xx unknown
1987
- 1987-11-19 US US07/123,016 patent/US4783464A/en not_active Expired - Fee Related
1988
- 1988-01-25 KE KE3797A patent/KE3797A/xx unknown
- 1988-05-19 HK HK371/88A patent/HK37188A/xx unknown
- 1988-09-02 CY CY1421A patent/CY1421A/xx unknown

Also Published As

Publication number	Publication date
BE894844A (fr)	1983-04-28
IL67156A (en)	1985-05-31
SE8206217L (sv)	1983-05-05
NZ202363A (en)	1985-12-13
SE450122B (sv)	1987-06-09
HK37188A (en)	1988-05-27
AT382374B (de)	1987-02-25
PT75773A (en)	1982-12-01
CY1421A (en)	1988-09-02
ES517082A0 (es)	1984-04-01
JPH0366306B2 (it)	1991-10-16
GB2108502A (en)	1983-05-18
PH20595A (en)	1987-02-24
FI71735B (fi)	1986-10-31
KE3797A (en)	1988-03-11
IT1189409B (it)	1988-02-04
HU187798B (en)	1986-02-28
ES8403898A1 (es)	1984-04-01
ATA400482A (de)	1986-07-15
CH653333A5 (de)	1985-12-31
AU9010782A (en)	1983-05-12
CA1193249A (en)	1985-09-10
US4783464A (en)	1988-11-08
FR2516084A1 (fr)	1983-05-13
AU561250B2 (en)	1987-05-07
IE54122B1 (en)	1989-06-21
DK486582A (da)	1983-05-05
SE8206217D0 (sv)	1982-11-02
ZA828104B (en)	1984-06-27
FR2516084B1 (it)	1985-01-11
FI823694L (fi)	1983-05-05
IE822627L (en)	1983-05-04
FI71735C (fi)	1987-02-09
JPS5885885A (ja)	1983-05-23
IL67156A0 (en)	1983-03-31
DE3239788A1 (de)	1983-05-11
GB2108502B (en)	1985-07-10
FI823694A0 (fi)	1982-10-28
MY8600310A (en)	1986-12-31
NL8204213A (nl)	1983-06-01

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