IT8121470A0 - Disolfuri misti utili quali agenti ipotensivi. - Google Patents
Disolfuri misti utili quali agenti ipotensivi.Info
- Publication number
- IT8121470A0 IT8121470A0 IT8121470A IT2147081A IT8121470A0 IT 8121470 A0 IT8121470 A0 IT 8121470A0 IT 8121470 A IT8121470 A IT 8121470A IT 2147081 A IT2147081 A IT 2147081A IT 8121470 A0 IT8121470 A0 IT 8121470A0
- Authority
- IT
- Italy
- Prior art keywords
- useful
- hypotensive agents
- mixed disulphides
- disulphides
- mixed
- Prior art date
Links
- 239000002220 antihypertensive agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/80—Antihypertensive peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/146,729 US4284624A (en) | 1980-05-02 | 1980-05-02 | Mixed disulfides |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8121470A0 true IT8121470A0 (it) | 1981-04-30 |
IT1167535B IT1167535B (it) | 1987-05-13 |
Family
ID=22518735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT21470/81A IT1167535B (it) | 1980-05-02 | 1981-04-30 | Disolfuri misti utili quali agenti ipotensivi |
Country Status (6)
Country | Link |
---|---|
US (4) | US4284624A (it) |
JP (1) | JPS56169662A (it) |
DE (1) | DE3117215A1 (it) |
FR (1) | FR2481698A1 (it) |
GB (1) | GB2075027A (it) |
IT (1) | IT1167535B (it) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4410542A (en) * | 1978-12-30 | 1983-10-18 | Santen Pharmaceutical Co., Ltd. | Disulfide compounds |
US4470972A (en) * | 1981-04-28 | 1984-09-11 | Schering Corporation | 7-Carboxyalkylaminoacyl-1,4-dithia-7-azaspiro[4.4]-nonane-8-carboxylic acids |
FR2498192A2 (fr) * | 1981-01-22 | 1982-07-23 | Pasteur Institut | Nouveau compose polypeptidique thiole provenant d'un fragment de la toxine tetanique, son procede d'obtention et ses applications |
ZA832844B (en) * | 1982-05-18 | 1984-03-28 | Smithkline Beckman Corp | Oligopeptide prodrugs |
US4427582A (en) * | 1982-06-08 | 1984-01-24 | Smithkline Beckman Corporation | Antimicrobial disulfide prodrugs |
US4826812A (en) * | 1982-12-27 | 1989-05-02 | Schering Corporation | Antiglaucoma agent |
US4596819A (en) * | 1984-01-23 | 1986-06-24 | Warner-Lambert Company | Modified tripeptides |
US4585757A (en) * | 1984-07-27 | 1986-04-29 | Texas Tech University Health Sciences Center | Hypotensive active peptides |
DE3769910D1 (de) * | 1986-10-24 | 1991-06-13 | Pfrimmer Kabi Gmbh & Co Kg | Verwendung von n, n'-bis-l-aminosaeure-l-cystinpeptiden in aminosaeure-praeparaten fuer orale und parenterale ernaehrung. |
AT402931B (de) * | 1986-11-07 | 1997-09-25 | Pharmacia Gmbh | Verfahren zur herstellung von neuen cystinverbindungen und derenverwendung |
US4847384A (en) * | 1987-03-12 | 1989-07-11 | Sandoz Pharm. Corp. | Process for the preparation of certain nitrogen-containing mono- and bicyclic ace inhibitors, and novel intermediates useful therefor |
US5089518A (en) * | 1989-01-23 | 1992-02-18 | American Cyanamid Company | 3- or 4-substituted oxotremorine derivatives and a method of treating cholinergic dysfunction therewith |
MY153288A (en) * | 2006-06-28 | 2015-01-29 | Hovid Berhad | An effective pharmaceutical carrier for poorly bioavailable drugs |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4091024A (en) * | 1976-12-03 | 1978-05-23 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
US4192878A (en) * | 1976-12-03 | 1980-03-11 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
US4129566A (en) * | 1978-02-15 | 1978-12-12 | E. R. Squibb & Sons, Inc. | Derivatives of dehydrocyclicimino acids |
US4113715A (en) * | 1977-01-17 | 1978-09-12 | E. R. Squibb & Sons, Inc. | Amino acid derivatives |
US4154935A (en) * | 1978-02-21 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Halogen substituted mercaptoacylamino acids |
CA1144930A (en) | 1978-08-11 | 1983-04-19 | Miguel A. Ondetti | Mercaptoacyl derivatives of substituted prolines |
CA1132985A (en) | 1978-12-22 | 1982-10-05 | John Krapcho | Ketal and thioketal derivatives of mercaptoacyl prolines |
US4217359A (en) * | 1979-01-15 | 1980-08-12 | E. R. Squibb & Sons, Inc. | Carbamate derivatives of mercaptoacyl hydroxy prolines |
US4216209A (en) * | 1979-03-19 | 1980-08-05 | American Home Products Corporation | Tripeptide angiotensin converting enzyme inhibitors |
US4234489A (en) * | 1979-06-25 | 1980-11-18 | E. R. Squibb & Sons, Inc. | Pyroglutamic acid derivatives and analogs |
-
1980
- 1980-05-02 US US06/146,729 patent/US4284624A/en not_active Expired - Lifetime
- 1980-12-22 US US06/219,176 patent/US4325944A/en not_active Expired - Fee Related
- 1980-12-22 US US06/219,283 patent/US4325945A/en not_active Expired - Fee Related
- 1980-12-22 US US06/219,043 patent/US4325943A/en not_active Expired - Fee Related
-
1981
- 1981-04-24 GB GB8112801A patent/GB2075027A/en not_active Withdrawn
- 1981-04-28 FR FR8108462A patent/FR2481698A1/fr active Pending
- 1981-04-30 DE DE19813117215 patent/DE3117215A1/de not_active Withdrawn
- 1981-04-30 IT IT21470/81A patent/IT1167535B/it active
- 1981-05-01 JP JP6756781A patent/JPS56169662A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
FR2481698A1 (fr) | 1981-11-06 |
US4325944A (en) | 1982-04-20 |
JPS56169662A (en) | 1981-12-26 |
GB2075027A (en) | 1981-11-11 |
US4284624A (en) | 1981-08-18 |
US4325945A (en) | 1982-04-20 |
US4325943A (en) | 1982-04-20 |
DE3117215A1 (de) | 1982-02-04 |
IT1167535B (it) | 1987-05-13 |
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