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IT8148952A0 - AMIDINATED AMINOGLUCOSIDES PROCEDURE FOR THEIR PREPARATION AND THEIR USE AS MEDICINES - Google Patents

AMIDINATED AMINOGLUCOSIDES PROCEDURE FOR THEIR PREPARATION AND THEIR USE AS MEDICINES

Info

Publication number
IT8148952A0
IT8148952A0 IT8148952A IT4895281A IT8148952A0 IT 8148952 A0 IT8148952 A0 IT 8148952A0 IT 8148952 A IT8148952 A IT 8148952A IT 4895281 A IT4895281 A IT 4895281A IT 8148952 A0 IT8148952 A0 IT 8148952A0
Authority
IT
Italy
Prior art keywords
amidinated
aminoglucosides
medicines
procedure
preparation
Prior art date
Application number
IT8148952A
Other languages
Italian (it)
Other versions
IT1171411B (en
Inventor
Loibner Hans
Streicher Wolfgang
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8148952A0 publication Critical patent/IT8148952A0/en
Application granted granted Critical
Publication of IT1171411B publication Critical patent/IT1171411B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IT48952/81A 1980-07-28 1981-07-22 AMMINOGLUCOSIDES AMMIDINATED PROCEDURE FOR THEIR PREPARATION AND USE AS A MEDICATION IT1171411B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH575680 1980-07-28
CH777880 1980-10-17
CH184281 1981-03-18

Publications (2)

Publication Number Publication Date
IT8148952A0 true IT8148952A0 (en) 1981-07-22
IT1171411B IT1171411B (en) 1987-06-10

Family

ID=27173293

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48952/81A IT1171411B (en) 1980-07-28 1981-07-22 AMMINOGLUCOSIDES AMMIDINATED PROCEDURE FOR THEIR PREPARATION AND USE AS A MEDICATION

Country Status (9)

Country Link
EP (1) EP0056408A1 (en)
JP (1) JPS57501084A (en)
CS (1) CS228516B2 (en)
GR (1) GR74312B (en)
IL (1) IL63429A0 (en)
IT (1) IT1171411B (en)
PT (1) PT73428B (en)
WO (1) WO1982000464A1 (en)
YU (1) YU184481A (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007064954A2 (en) 2005-12-02 2007-06-07 Isis Pharmaceuticals, Inc. Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
EP2324076B1 (en) 2008-07-31 2017-11-01 3M Innovative Properties Company Fluoropolymer compositions and method of making and using thereof
EP2315802A4 (en) * 2008-07-31 2012-04-18 3M Innovative Properties Co Azide compositions and methods of making and using thereof
WO2010030690A1 (en) 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
EP2486044A2 (en) 2009-10-09 2012-08-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
AR083879A1 (en) 2010-11-17 2013-03-27 Achaogen Inc ANTIBACTERIAL AMINOGLYCOSID ANALOGS, METHODS OF PREPARATION AND USE AS THERAPEUTIC AGENTS
CN116462721B (en) * 2023-04-18 2024-02-02 江南大学 Antibacterial aminoglycoside derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1087537A (en) * 1975-08-21 1980-10-14 John H. E. J. Martin Antibiotic bm123 and production thereof
JPS5488241A (en) * 1977-12-21 1979-07-13 Kyowa Hakko Kogyo Co Ltd Novel fortimicin a derivative

Also Published As

Publication number Publication date
WO1982000464A1 (en) 1982-02-18
JPS57501084A (en) 1982-06-24
PT73428B (en) 1983-01-13
IL63429A0 (en) 1981-10-30
IT1171411B (en) 1987-06-10
EP0056408A1 (en) 1982-07-28
YU184481A (en) 1983-09-30
PT73428A (en) 1981-08-01
CS228516B2 (en) 1984-05-14
GR74312B (en) 1984-06-22

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