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IT8023161A0 - COMPOUNDS WITH NON-ASSIMILABLE MUCOLYTIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS WHICH INCLUDE THEM AS ACTIVE INGREDIENTS. - Google Patents

COMPOUNDS WITH NON-ASSIMILABLE MUCOLYTIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS WHICH INCLUDE THEM AS ACTIVE INGREDIENTS.

Info

Publication number
IT8023161A0
IT8023161A0 IT8023161A IT2316180A IT8023161A0 IT 8023161 A0 IT8023161 A0 IT 8023161A0 IT 8023161 A IT8023161 A IT 8023161A IT 2316180 A IT2316180 A IT 2316180A IT 8023161 A0 IT8023161 A0 IT 8023161A0
Authority
IT
Italy
Prior art keywords
assimilable
compounds
preparation
active ingredients
therapeutic compositions
Prior art date
Application number
IT8023161A
Other languages
Italian (it)
Other versions
IT1209419B (en
Inventor
Maltz Javier Esteban
Original Assignee
Texcontor Ets
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texcontor Ets filed Critical Texcontor Ets
Publication of IT8023161A0 publication Critical patent/IT8023161A0/en
Priority to IT8023161A priority Critical patent/IT1209419B/en
Priority to FR8017656A priority patent/FR2485925A1/en
Priority to US06/184,249 priority patent/US4409138A/en
Priority to EP81830099A priority patent/EP0045285B1/en
Priority to DE8181830099T priority patent/DE3163287D1/en
Priority to AT81830099T priority patent/ATE7202T1/en
Priority to CA000380788A priority patent/CA1168169A/en
Priority to ES503527A priority patent/ES503527A0/en
Priority to AU72412/81A priority patent/AU7241281A/en
Priority to JP56101394A priority patent/JPS5813522A/en
Priority to YU01636/81A priority patent/YU163681A/en
Priority to US06/512,679 priority patent/US4559322A/en
Application granted granted Critical
Publication of IT1209419B publication Critical patent/IT1209419B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)
    • C12Y301/21001—Deoxyribonuclease I (3.1.21.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IT8023161A 1980-07-01 1980-07-01 COMPOUNDS WITH NON-SIMILAR MUCOLITICAL ACTIVITIES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS THAT INCLUDE THEM AS AN ACTIVE INGREDIENT. IT1209419B (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT8023161A IT1209419B (en) 1980-07-01 1980-07-01 COMPOUNDS WITH NON-SIMILAR MUCOLITICAL ACTIVITIES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS THAT INCLUDE THEM AS AN ACTIVE INGREDIENT.
FR8017656A FR2485925A1 (en) 1980-07-01 1980-08-11 CARBON SKELETAL COMPOUNDS WITH ENZYMATIC AND SULFHYDRYL RADICALS AND COMPRISING MUCOLYTIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS CONTAINING SAME AS ACTIVE INGREDIENT
US06/184,249 US4409138A (en) 1980-07-01 1980-09-05 Non-absorbable compounds of mucolytic activity, the process for their preparation, and therapeutic compositions which contain them as active principle
EP81830099A EP0045285B1 (en) 1980-07-01 1981-06-19 Non absorbable compounds of mucolytic activity, the process for their preparation and therapeutic compositions which contain them as active principle
DE8181830099T DE3163287D1 (en) 1980-07-01 1981-06-19 Non absorbable compounds of mucolytic activity, the process for their preparation and therapeutic compositions which contain them as active principle
AT81830099T ATE7202T1 (en) 1980-07-01 1981-06-19 NON-ADSORBABLE MUCOLYTIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS CONTAINING THESE COMPOUNDS AS AN ACTIVE SUBSTANCE.
CA000380788A CA1168169A (en) 1980-07-01 1981-06-29 Non absorbable compounds of mucolytic activity, the process for their preparation and therapeutic compositions which contain them as active principle
ES503527A ES503527A0 (en) 1980-07-01 1981-06-30 A PROCEDURE FOR THE PREPARATION OF MARCROMO-LECULAR COMPOUNDS OF MUCOLYTIC ACTIVITY AND NOT ABSORBABLE BY TISSUES
AU72412/81A AU7241281A (en) 1980-07-01 1981-06-30 Compounds of mucolytic activity
JP56101394A JPS5813522A (en) 1980-07-01 1981-07-01 Mucus-dissolution-active non-absorbing compound, manufacture and therapeutical composition containing same as active component
YU01636/81A YU163681A (en) 1980-07-01 1981-07-01 Process for obtaining compounds of mucolytic activity which are not absorbed in tissues
US06/512,679 US4559322A (en) 1980-07-01 1983-07-11 Non-absorbable compounds of mucolytic activity, the process for their preparation, and therapeutic compositions which contain them as active principle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8023161A IT1209419B (en) 1980-07-01 1980-07-01 COMPOUNDS WITH NON-SIMILAR MUCOLITICAL ACTIVITIES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS THAT INCLUDE THEM AS AN ACTIVE INGREDIENT.

Publications (2)

Publication Number Publication Date
IT8023161A0 true IT8023161A0 (en) 1980-07-01
IT1209419B IT1209419B (en) 1989-07-16

Family

ID=11204417

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8023161A IT1209419B (en) 1980-07-01 1980-07-01 COMPOUNDS WITH NON-SIMILAR MUCOLITICAL ACTIVITIES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS THAT INCLUDE THEM AS AN ACTIVE INGREDIENT.

Country Status (11)

Country Link
US (2) US4409138A (en)
EP (1) EP0045285B1 (en)
JP (1) JPS5813522A (en)
AT (1) ATE7202T1 (en)
AU (1) AU7241281A (en)
CA (1) CA1168169A (en)
DE (1) DE3163287D1 (en)
ES (1) ES503527A0 (en)
FR (1) FR2485925A1 (en)
IT (1) IT1209419B (en)
YU (1) YU163681A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU574360B2 (en) * 1983-05-13 1988-07-07 Reichert, D. Antisnoring agent
US4585754A (en) * 1984-01-09 1986-04-29 Valcor Scientific, Ltd. Stabilization of proteins and peptides by chemical binding with chondroitin
CA1317860C (en) * 1987-04-01 1993-05-18 Daniel Louis Kacian Techniques for preparing specimens for bacterial assays
US5128132A (en) * 1988-11-22 1992-07-07 Parnell Pharmaceuticals, Inc. Eriodictyon compositions and methods for treating internal mucous membranes
CA2447886A1 (en) * 2001-07-03 2003-01-16 Alcon, Inc. Compositions for removing human cerumen
US20060182705A1 (en) * 2005-02-11 2006-08-17 Cruse Maria K Composition for reduction and prevention of wrinkles on the skin
EP3797783A1 (en) * 2019-09-27 2021-03-31 Freie Universität Berlin Novel medical uses of thiol-functionalized polyglycerol derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR924877A (en) * 1946-03-15 1947-08-19 Manufacturing process of veterinary preparations
US4004979A (en) * 1968-03-29 1977-01-25 Agence Nationale De Valorisation De La Recherche (Anvar) Preparation of active proteins cross-linked to inactive proteins
NL6812443A (en) * 1968-08-31 1970-03-03
BE758425A (en) * 1969-12-02 1971-04-16 Baxter Laboratories Inc STREPTOKINASE CHEMICALLY LINKED TO A CARBOHYDRATE MATRIX (
US3683069A (en) * 1970-02-19 1972-08-08 Michel Hooreman Enzymatic products which optimize the viscosity of mucuses and their applications
JPS5443074B1 (en) * 1971-04-14 1979-12-18
BE790326A (en) * 1971-10-20 1973-04-19 Pechiney Ugine Kuhlmann NEW HYDROXYQUINOLEINE DERIVATIVE
US4185090A (en) * 1972-02-02 1980-01-22 Abbott Laboratories Chemically modified endotoxin immunizing agent
GB1479268A (en) * 1973-07-05 1977-07-13 Beecham Group Ltd Pharmaceutical compositions
SE431758B (en) * 1977-03-04 1984-02-27 Pharmacia Fine Chemicals Ab AS THE USE OF THE TIOLATION REAGENT OR BERRY MATRIX FOR ENZYMERS DERIVATIVE OF A SH GROUPING POLYMER
CS204190B1 (en) * 1978-02-22 1981-03-31 Jaroslav Drobnik Activation method for hydrxyl groups containing insoluble carriers
US4259233A (en) * 1979-10-23 1981-03-31 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates

Also Published As

Publication number Publication date
JPS5813522A (en) 1983-01-26
ES8203420A1 (en) 1982-04-01
ATE7202T1 (en) 1984-05-15
ES503527A0 (en) 1982-04-01
YU163681A (en) 1983-09-30
US4559322A (en) 1985-12-17
CA1168169A (en) 1984-05-29
US4409138A (en) 1983-10-11
EP0045285A1 (en) 1982-02-03
IT1209419B (en) 1989-07-16
AU7241281A (en) 1982-01-07
FR2485925B1 (en) 1985-05-24
EP0045285B1 (en) 1984-04-25
DE3163287D1 (en) 1984-05-30
FR2485925A1 (en) 1982-01-08

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