IT1393338B1 - Uso terapeutico della metadoxina come inibitore della fibrosi epatica. - Google Patents
Uso terapeutico della metadoxina come inibitore della fibrosi epatica.Info
- Publication number
- IT1393338B1 IT1393338B1 ITMI2009A000333A ITMI20090333A IT1393338B1 IT 1393338 B1 IT1393338 B1 IT 1393338B1 IT MI2009A000333 A ITMI2009A000333 A IT MI2009A000333A IT MI20090333 A ITMI20090333 A IT MI20090333A IT 1393338 B1 IT1393338 B1 IT 1393338B1
- Authority
- IT
- Italy
- Prior art keywords
- metadoxine
- inhibitor
- therapeutic use
- liver fibrosis
- fibrosis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2009A000333A IT1393338B1 (it) | 2009-03-06 | 2009-03-06 | Uso terapeutico della metadoxina come inibitore della fibrosi epatica. |
PT107125197T PT2403495E (pt) | 2009-03-06 | 2010-03-04 | Metadoxina para utilização como inibidor da fibrose hepática |
EP10712519.7A EP2403495B1 (en) | 2009-03-06 | 2010-03-04 | Metadoxine for use as inhibitor of hepatic fibrosis. |
US13/138,536 US20120029031A1 (en) | 2009-03-06 | 2010-03-04 | Metadoxine for use as inhibitor of hepatic fibrosis |
ES10712519.7T ES2544780T3 (es) | 2009-03-06 | 2010-03-04 | Metadoxina para su uso como inhibidor de fibrosis hepática |
PCT/IB2010/050930 WO2010100619A1 (en) | 2009-03-06 | 2010-03-04 | Metadoxine for use as inhibitor of hepatic fibrosis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2009A000333A IT1393338B1 (it) | 2009-03-06 | 2009-03-06 | Uso terapeutico della metadoxina come inibitore della fibrosi epatica. |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI20090333A1 ITMI20090333A1 (it) | 2010-09-07 |
IT1393338B1 true IT1393338B1 (it) | 2012-04-20 |
Family
ID=41202480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI2009A000333A IT1393338B1 (it) | 2009-03-06 | 2009-03-06 | Uso terapeutico della metadoxina come inibitore della fibrosi epatica. |
Country Status (6)
Country | Link |
---|---|
US (1) | US20120029031A1 (it) |
EP (1) | EP2403495B1 (it) |
ES (1) | ES2544780T3 (it) |
IT (1) | IT1393338B1 (it) |
PT (1) | PT2403495E (it) |
WO (1) | WO2010100619A1 (it) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011061743A1 (en) * | 2009-11-18 | 2011-05-26 | Alcobra Ltd. | Metadoxine and derivatives thereof for use in the treatment of inflammation and immune-related disorders |
BR112015006642B1 (pt) * | 2012-09-26 | 2022-08-02 | Eurodrug Laboratories B.V | Composição farmacêutica de liberação prolongada compreendendo metadoxina e prednisona |
EP3035221A1 (en) * | 2014-12-19 | 2016-06-22 | John Rovnan | Systems and methods for managing an electronic database |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1131856B (it) * | 1980-06-30 | 1986-06-25 | Baldacci Lab Spa | Composizione farmaceutica per il trattamento di intossicazioni alcooliche |
KR100877600B1 (ko) * | 2006-11-30 | 2009-01-08 | 재단법인서울대학교산학협력재단 | 메타독신 및 마늘유를 유효성분으로 함유하는 알코올성지방간 및 지방간성 간염의 예방 및 치료용 약학 조성물 |
-
2009
- 2009-03-06 IT ITMI2009A000333A patent/IT1393338B1/it active
-
2010
- 2010-03-04 WO PCT/IB2010/050930 patent/WO2010100619A1/en active Application Filing
- 2010-03-04 EP EP10712519.7A patent/EP2403495B1/en active Active
- 2010-03-04 ES ES10712519.7T patent/ES2544780T3/es active Active
- 2010-03-04 PT PT107125197T patent/PT2403495E/pt unknown
- 2010-03-04 US US13/138,536 patent/US20120029031A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2403495A1 (en) | 2012-01-11 |
PT2403495E (pt) | 2015-09-17 |
ES2544780T3 (es) | 2015-09-03 |
ITMI20090333A1 (it) | 2010-09-07 |
EP2403495B1 (en) | 2015-05-20 |
WO2010100619A1 (en) | 2010-09-10 |
US20120029031A1 (en) | 2012-02-02 |
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