IT1296464B1 - PHARMACEUTICAL COMPOSITIONS IN THE FORM OF DRUG-LOADED CROSS-LINKED POLYMER POWDERS AND RELATED PREPARATION PROCESS BY MEANS - Google Patents

PHARMACEUTICAL COMPOSITIONS IN THE FORM OF DRUG-LOADED CROSS-LINKED POLYMER POWDERS AND RELATED PREPARATION PROCESS BY MEANS

Info

Publication number: IT1296464B1
Authority: IT; Italy
Prior art keywords: drug; pharmaceutical compositions; preparation process; linked polymer; polymer powders
Prior art date: 1997-11-19

Application number

IT97MI002571A

Other languages

Italian (it)

Inventor

Fabio Carli

Italo Colombo

Paolo Alessi

Ireneo Kikic

Angelo Cortesi

Original Assignee

Vectorpharma Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-19

Filing date

1997-11-19

Publication date

1999-06-25

1997-11-19 Priority to IT97MI002571A priority Critical patent/IT1296464B1/en

1997-11-19 Application filed by Vectorpharma Int filed Critical Vectorpharma Int

1998-11-16 Priority to JP2000520756A priority patent/JP2001522873A/en

1998-11-16 Priority to CA002310423A priority patent/CA2310423A1/en

1998-11-16 Priority to EP98965674A priority patent/EP1033977A2/en

1998-11-16 Priority to PCT/EP1998/007311 priority patent/WO1999025322A2/en

1998-11-16 Priority to NZ505290A priority patent/NZ505290A/en

1998-11-16 Priority to BR9814656-4A priority patent/BR9814656A/en

1998-11-16 Priority to KR1020007005454A priority patent/KR20010032251A/en

1998-11-16 Priority to AU21531/99A priority patent/AU738748B2/en

1999-05-19 Publication of ITMI972571A1 publication Critical patent/ITMI972571A1/en

1999-06-25 Application granted granted Critical

1999-06-25 Publication of IT1296464B1 publication Critical patent/IT1296464B1/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

IT97MI002571A 1997-11-19 1997-11-19 PHARMACEUTICAL COMPOSITIONS IN THE FORM OF DRUG-LOADED CROSS-LINKED POLYMER POWDERS AND RELATED PREPARATION PROCESS BY MEANS IT1296464B1 (en)

Priority Applications (9)

Application Number	Priority Date	Filing Date	Title
IT97MI002571A IT1296464B1 (en)	1997-11-19	1997-11-19	PHARMACEUTICAL COMPOSITIONS IN THE FORM OF DRUG-LOADED CROSS-LINKED POLYMER POWDERS AND RELATED PREPARATION PROCESS BY MEANS
CA002310423A CA2310423A1 (en)	1997-11-19	1998-11-16	Pharmaceutical compositions having the shape of powders of cross-linked polymers loaded with drugs and related preparation process by supercritical fluids
EP98965674A EP1033977A2 (en)	1997-11-19	1998-11-16	Pharmaceutical compositions having the shape of powders of cross-linked polymers loaded with drugs and related preparation process by supercritical fluids
PCT/EP1998/007311 WO1999025322A2 (en)	1997-11-19	1998-11-16	Pharmaceutical compositions having the shape of powders of cross-linked polymers loaded with drugs and related preparation process by supercritical fluids
JP2000520756A JP2001522873A (en)	1997-11-19	1998-11-16	Pharmaceutical compositions having crosslinked polymers in powder form bearing pharmaceuticals and related supercritical fluid preparation methods
NZ505290A NZ505290A (en)	1997-11-19	1998-11-16	Pharmaceutical compositions comprising cross-linked polymers loaded with drugs prepared by using supercritical fluids to solubilize and load the drugs on to the polymers
BR9814656-4A BR9814656A (en)	1997-11-19	1998-11-16	Pharmaceutical compositions in the form of powders, and process for the preparation of pharmaceutical compositions
KR1020007005454A KR20010032251A (en)	1997-11-19	1998-11-16	Pharmaceutical compositions having the shape of powders of cross-linked polymers loaded with drugs and related preparation process by supercritical fluids
AU21531/99A AU738748B2 (en)	1997-11-19	1998-11-16	Pharmaceutical compositions having the shape of powders of cross-linked polymers loaded with drugs and related preparation process by supercritical fluids

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT97MI002571A IT1296464B1 (en)	1997-11-19	1997-11-19	PHARMACEUTICAL COMPOSITIONS IN THE FORM OF DRUG-LOADED CROSS-LINKED POLYMER POWDERS AND RELATED PREPARATION PROCESS BY MEANS

Publications (2)

Publication Number	Publication Date
ITMI972571A1 ITMI972571A1 (en)	1999-05-19
IT1296464B1 true IT1296464B1 (en)	1999-06-25

Family

ID=11378230

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT97MI002571A IT1296464B1 (en)	1997-11-19	1997-11-19	PHARMACEUTICAL COMPOSITIONS IN THE FORM OF DRUG-LOADED CROSS-LINKED POLYMER POWDERS AND RELATED PREPARATION PROCESS BY MEANS

Country Status (9)

Country	Link
EP (1)	EP1033977A2 (en)
JP (1)	JP2001522873A (en)
KR (1)	KR20010032251A (en)
AU (1)	AU738748B2 (en)
BR (1)	BR9814656A (en)
CA (1)	CA2310423A1 (en)
IT (1)	IT1296464B1 (en)
NZ (1)	NZ505290A (en)
WO (1)	WO1999025322A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9920558D0 (en) *	1999-08-31	1999-11-03	Bradford Particle Design Ltd	Methods for particle formation and their products
WO2001052981A1 (en) *	2000-01-17	2001-07-26	Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.	Method for modifying the surfaces of fine-porous adsorbents
IT1318404B1 (en) *	2000-03-17	2003-08-25	Eurand Int	PROCESS FOR THE PREPARATION OF FORMULATIONS WITH ACCELERATED RELEASE WITH THE USE OF COMPRESSED FLUIDS.
EP1258241A1 (en) *	2001-05-16	2002-11-20	BIOPROGRESS S.p.A.	Method of increasing the bioavailability of nimesulide
ES2305250T3 (en) *	2001-05-30	2008-11-01	Csir	ENCAPSULATION PROCEDURE OF AN ACTIVE SUBSTANCE.
US20030044514A1 (en) *	2001-06-13	2003-03-06	Richard Robert E.	Using supercritical fluids to infuse therapeutic on a medical device
DE10132366A1 (en) *	2001-07-04	2003-01-30	Degussa	Process for the physical treatment of starch (derivatives)
FR2830760B1 (en)	2001-10-12	2004-06-04	Pf Medicament	PROCESS FOR THE PREPARATION OF AN INTERACTION COMPOUND OF ACTIVE SUBSTANCES WITH A POROUS SUPPORT BY SUPERCRITICAL FLUID
GB0127786D0 (en) *	2001-11-20	2002-01-09	Univ Nottingham	Impregnation of antimicrobial substances
EP1515699B1 (en) *	2002-03-07	2009-02-04	Eurand Pharmaceuticals Ltd.	Process for loading and thermodynamically activating drugs on polymers by means of supercritical fluids
KR100508518B1 (en) *	2002-11-13	2005-08-17	한미약품 주식회사	Method for the preparation of paclitaxel solid dispersion by using the supercritical fluid process and paclitaxel solid dispersion prepared thereby
FR2854079B1 (en)	2003-04-25	2007-11-30	Pf Medicament	PROCESS FOR THE PREPARATION OF MOLECULAR COMPLEXES
US7507823B2 (en)	2004-05-06	2009-03-24	Bristol-Myers Squibb Company	Process of making aripiprazole particles
EP1611877A1 (en)	2004-06-28	2006-01-04	Universidade de Coimbra	Method for preparing sustained-release therapeutic ophthalmic articles using compressed fluids for impregnation of drugs
GB2417900A (en) *	2004-09-11	2006-03-15	Medway Science Technologies Lt	Composition for oral drug delivery
KR101374928B1 (en) *	2005-11-09	2014-03-14	노파르티스 아게	Process for making pharmaceutical compositions with a transient plasticizer
GB0812742D0 (en)	2008-07-11	2008-08-20	Critical Pharmaceuticals Ltd	Process
FR2945449B1 (en) *	2009-05-15	2012-10-05	Pf Medicament	SUPERCRITICAL CO2 IMPREGNATION PROCESS
CN105687141A (en) *	2016-03-04	2016-06-22	中国药科大学	Technical study for preparing Nim-PLLA (nimesulide-poly-l-lactic acid) composite microsphere with supercritical anti-solvent method
CN112812355B (en) *	2020-12-31	2022-09-23	厦门天生爱科技有限公司	Functional polymer foaming material with slow-release volatile Chinese herbal medicine effective components, preparation method and application
CN113425895A (en) *	2021-07-12	2021-09-24	大连大学	Drug-loaded bone repair internal fixation material and preparation method thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE63321B1 (en) *	1986-02-03	1995-04-05	Elan Corp Plc	Drug delivery system
FR2635043B1 (en) *	1988-08-05	1990-09-28	Michelin & Cie	APPARATUS FOR MANUFACTURING A REINFORCEMENT FOR TIRES, SAID REINFORCEMENT MADE FROM A SINGLE THREAD
CH677876A5 (en) *	1988-10-21	1991-07-15	Siegfried Ag	Prepn. of coronary active 1,4-di:hydro-pyridine(s) in sorbed form - by pptn. on and/or in polyacrylate particles to improve bio-availability
IT1252867B (en) *	1991-12-31	1995-06-28	Gentili Ist Spa	PHARMACEUTICAL COMPOSITIONS CONTAINING HIGH-BIOAVAILABILITY PROGESTERONE
DE4202320A1 (en) *	1992-01-29	1993-08-05	Dierk Dr Knittel	Impregnating substrate by contact with supercritical fluid contg. impregnant - followed by conversion of fluid to subcritical state
US5340614A (en) *	1993-02-11	1994-08-23	Minnesota Mining And Manufacturing Company	Methods of polymer impregnation

1997
- 1997-11-19 IT IT97MI002571A patent/IT1296464B1/en active IP Right Grant
1998
- 1998-11-16 CA CA002310423A patent/CA2310423A1/en not_active Abandoned
- 1998-11-16 AU AU21531/99A patent/AU738748B2/en not_active Ceased
- 1998-11-16 EP EP98965674A patent/EP1033977A2/en not_active Withdrawn
- 1998-11-16 JP JP2000520756A patent/JP2001522873A/en active Pending
- 1998-11-16 NZ NZ505290A patent/NZ505290A/en unknown
- 1998-11-16 KR KR1020007005454A patent/KR20010032251A/en not_active Withdrawn
- 1998-11-16 BR BR9814656-4A patent/BR9814656A/en not_active IP Right Cessation
- 1998-11-16 WO PCT/EP1998/007311 patent/WO1999025322A2/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO1999025322A2 (en)	1999-05-27
KR20010032251A (en)	2001-04-16
JP2001522873A (en)	2001-11-20
CA2310423A1 (en)	1999-05-27
AU738748B2 (en)	2001-09-27
WO1999025322A3 (en)	1999-08-19
AU2153199A (en)	1999-06-07
ITMI972571A1 (en)	1999-05-19
NZ505290A (en)	2002-08-28
EP1033977A2 (en)	2000-09-13
BR9814656A (en)	2000-10-03

Publication	Publication Date	Title
IT1296464B1 (en)	1999-06-25	PHARMACEUTICAL COMPOSITIONS IN THE FORM OF DRUG-LOADED CROSS-LINKED POLYMER POWDERS AND RELATED PREPARATION PROCESS BY MEANS
IT1298575B1 (en)	2000-01-12	PHARMACEUTICAL COMPOSITIONS IN THE FORM OF NANOPARTICLES INCLUDING LIPID SUBSTANCES AND ANTIPHILIC SUBSTANCES AND RELATED PROCESS OF
ITMI950568A0 (en)	1995-03-22	PHARMACEUTICAL FORMULATIONS IN THE FORM OF THIXOTROPIC GEL
BR9804802B1 (en)	2011-04-19	sustained release composition of encapsulated drugs in hyaluronic acid microparticles.
FI972964A0 (en)	1997-07-11	Biodegradable polymers, methods for their preparation and their use in the manufacture of biodegradable molding products
DK0809666T4 (en)	2002-12-02	Biodegradable Polymers, Methods for their Preparation, and Their Use in the Preparation of Biodegradable Form Bodies
ID23978A (en)	2000-06-14	TIENOPIRIMIDIN AND TIENOPIRIDIN DERIVES USED AS ANTI-CANCER SUBSTANCES
DE69829017D1 (en)	2005-03-24	Hydrophobically modified polysaccharide in personal care products
DE69806420D1 (en)	2002-08-14	In-mold coating compositions, their preparation and methods
NO995925D0 (en)	1999-12-03	Pharmaceutical compositions comprising cyclodextrins
BR9611251A (en)	1999-03-30	Powder composition redispersible in water Process of preparing the same pseudo-latex and using it
ID21019A (en)	1999-04-08	PIRAZOL DISTRIBUTION, IT IS CREATED AND USED IN PHARMACEUTICAL PROPERTIES
DK1849831T3 (en)	2010-03-08	The epoxy-polysiloxane polymer composition
FI971983A7 (en)	1997-06-10	Redispersible polymer powder mixtures containing cyclodextrin or cyclodextrin derivatives
NO20010893D0 (en)	2001-02-22	Stabilized pharmaceutical material in lyophilized form
NO973612D0 (en)	1997-08-05	New pharmaceutical preparation
LV12624A (en)	2001-03-20	Thienylazolylalcoxyethanamines their preparation and their application as medicaments
NO20000284D0 (en)	2000-01-20	Tannic acid polymer compositions for controlled release of pharmaceutical agents, especially in the oral cavity
DK0845982T3 (en)	2002-03-25	Use of Lipids as Adjuvants in the Preparation of Solid Drug Forms in the Melt Extrusion Process
IL150119A0 (en)	2002-12-01	Amphiphilic polymers and polypeptide conjugates comprising same
ID29089A (en)	2001-07-26	MOKSIFLOXASIN PHARMACEUTICAL PROPERTIES
ITMI950711A0 (en)	1995-04-07	EFFECTIVE COMPOSITION IN THE REMOVAL OF ASPHALTENES
KR100547921B1 (en)	2006-10-19	Sulfonamide-substituted chromamann, methods for the preparation thereof and pharmaceutical compositions comprising the same
WO1999039692A3 (en)	1999-09-23	Pharmaceutical compositions in form of polymeric microparticles obtained by extrusion and spheronization
BR9611249A (en)	1999-05-04	Powdery composition redispersible in water. Process of preparing the same pseudo-latex and using it

Legal Events

Date	Code	Title	Description
1999-06-25	0001	Granted