IT1190353B - CEFEM COMPOUNDS WITH ANTIBACTERIAL ACTIVITY, RELATED PREPARATION AND INTERMEDIATE PROCEDURE FOR THIS - Google Patents

CEFEM COMPOUNDS WITH ANTIBACTERIAL ACTIVITY, RELATED PREPARATION AND INTERMEDIATE PROCEDURE FOR THIS

Info

Publication number: IT1190353B
Authority: IT; Italy
Prior art keywords: antibacterial activity; related preparation; intermediate procedure; cefem compounds; cefem
Prior art date: 1984-04-09

Application number

IT20267/85A

Other languages

Italian (it)

Other versions

IT8520267A0 (en

Inventor

Yamashita Haruhiro

Oka Masahisa

Okumura Jun

Naito Takayuki

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-04-09

Filing date

1985-04-05

Publication date

1988-02-16

1985-04-05 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1985-04-05 Publication of IT8520267A0 publication Critical patent/IT8520267A0/en

1988-02-16 Application granted granted Critical

1988-02-16 Publication of IT1190353B publication Critical patent/IT1190353B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IT20267/85A 1984-04-09 1985-04-05 CEFEM COMPOUNDS WITH ANTIBACTERIAL ACTIVITY, RELATED PREPARATION AND INTERMEDIATE PROCEDURE FOR THIS IT1190353B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US59794184A	1984-04-09	1984-04-09

Publications (2)

Publication Number	Publication Date
IT8520267A0 IT8520267A0 (en)	1985-04-05
IT1190353B true IT1190353B (en)	1988-02-16

Family

ID=24393575

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT20267/85A IT1190353B (en)	1984-04-09	1985-04-05	CEFEM COMPOUNDS WITH ANTIBACTERIAL ACTIVITY, RELATED PREPARATION AND INTERMEDIATE PROCEDURE FOR THIS

Country Status (31)

Country	Link
JP (4)	JPS615084A (en)
KR (1)	KR870002166B1 (en)
AR (1)	AR244694A1 (en)
AT (1)	AT388735B (en)
AU (2)	AU580990B2 (en)
BE (1)	BE902148A (en)
CA (3)	CA1276929C (en)
CH (1)	CH669197A5 (en)
DD (3)	DD249024A5 (en)
DE (1)	DE3512225A1 (en)
DK (1)	DK155985A (en)
ES (4)	ES8607318A1 (en)
FI (1)	FI84830C (en)
FR (1)	FR2563832B1 (en)
GB (3)	GB2157293B (en)
GR (1)	GR850883B (en)
HU (2)	HU193750B (en)
IE (2)	IE58408B1 (en)
IL (1)	IL74826A (en)
IT (1)	IT1190353B (en)
LU (1)	LU85840A1 (en)
MY (1)	MY101940A (en)
NL (1)	NL192925C (en)
NZ (1)	NZ211659A (en)
OA (1)	OA07985A (en)
PT (1)	PT80246B (en)
RU (1)	RU2056425C1 (en)
SE (4)	SE466205B (en)
SU (4)	SU1487814A3 (en)
YU (2)	YU46151B (en)
ZA (1)	ZA852236B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61145186A (en) *	1984-12-20	1986-07-02	Meiji Seika Kaisha Ltd	Novel cephem compound and preparation thereof
US4708955A (en) *	1985-06-24	1987-11-24	Bristol-Myers Company	3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
EP0329785B1 (en) *	1985-12-26	1994-11-30	Eisai Co., Ltd.	Cephalosporin derivatives
IL84128A (en) *	1986-10-13	1992-12-01	Eisai Co Ltd	3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
AU614723B2 (en) *	1986-10-13	1991-09-12	Eisai Co. Ltd.	3-propenylcephem derivative
JPH085897B2 (en) *	1986-11-06	1996-01-24	エーザイ株式会社	3-propenyl cephem derivative
FR2622585B1 (en) *	1987-11-03	1991-04-19	Roussel Uclaf	NOVEL CEPHALOSPORINS COMPRISING IN POSITION 3 A SUBSTITUTED VINYL RADICAL, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS, THE COMPOSITIONS CONTAINING THEM AND THE NEW INTERMEDIATES OBTAINED
CA1339738C (en) *	1988-03-16	1998-03-17	Takashi Kamiya	Process for the preparation of cephem derivatives and entermediates therefor
JPH0699449B2 (en) *	1988-03-16	1994-12-07	エーザイ株式会社	Synthetic intermediate of cephem derivative
FR2655042B1 (en) *	1989-11-29	1994-01-21	Adir Cie	NOVEL SUBSTITUTED BENZOTHIAZOLINONES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2663332B1 (en) *	1990-06-15	1997-11-07	Roussel Uclaf	NOVEL CEPHALOSPORINS COMPRISING IN POSITION 3 A RADICAL PROPENYL SUBSTITUTED BY A QUATERNARY AMMONIUM, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS, THE COMPOSITIONS CONTAINING THEM AND THE NEW INTERMEDIATES OBTAINED.
US5126336A (en) *	1990-08-23	1992-06-30	Bristol-Myers Squibb Company	Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (en) *	1991-08-21	1993-06-25	Biochemie Gmbh	NEW PROCESS AND NEW INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVES
JPH0741484A (en) *	1993-07-29	1995-02-10	Katayama Seiyakushiyo:Kk	Cephem compound and antimicrobial agent
WO1996005205A1 (en) *	1994-08-16	1996-02-22	Meiji Seika Kabushiki Kaisha	Novel cephem derivative
EP1090013A1 (en)	1998-06-22	2001-04-11	F. Hoffmann-La Roche Ag	Propenyl cephalosporin derivatives
CN100398547C (en)	2003-09-09	2008-07-02	日本化学工业株式会社	Process for producing 3-chloromethyl-3-cephem derivative

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1342241A (en) *	1970-01-23	1974-01-03	Glaxo Lab Ltd	Cephalosporin compounds
US4390534A (en) *	1978-12-29	1983-06-28	Fujisawa Pharmaceutical Co., Ltd.	Cephem and cepham compounds
EP0025017A1 (en) *	1979-08-28	1981-03-11	Ciba-Geigy Ag	Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter
US4409214A (en) *	1979-11-19	1983-10-11	Fujisawa Pharmaceutical, Co., Ltd.	7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (en) *	1980-06-18	1984-08-02	Fujisawa Pharmaceutical Co
GR78245B (en) *	1980-09-12	1984-09-26	Ciba Geigy Ag
US4521413A (en) *	1981-09-14	1985-06-04	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
US4486586A (en) *	1983-02-10	1984-12-04	Bristol-Myers Company	Cephalosporin derivatives

1985
- 1985-02-14 CA CA000474260A patent/CA1276929C/en not_active Expired - Lifetime
- 1985-03-25 ZA ZA852236A patent/ZA852236B/en unknown
- 1985-04-02 AR AR85299945A patent/AR244694A1/en active
- 1985-04-02 NZ NZ211659A patent/NZ211659A/en unknown
- 1985-04-03 DK DK155985A patent/DK155985A/en not_active Application Discontinuation
- 1985-04-03 DD DD85287524A patent/DD249024A5/en unknown
- 1985-04-03 DE DE19853512225 patent/DE3512225A1/en active Granted
- 1985-04-03 SE SE8501680A patent/SE466205B/en not_active IP Right Cessation
- 1985-04-03 DD DD85274832A patent/DD236735A5/en unknown
- 1985-04-04 IE IE86685A patent/IE58408B1/en not_active IP Right Cessation
- 1985-04-04 NL NL8501002A patent/NL192925C/en not_active IP Right Cessation
- 1985-04-04 FI FI851379A patent/FI84830C/en not_active IP Right Cessation
- 1985-04-04 AU AU40862/85A patent/AU580990B2/en not_active Expired
- 1985-04-04 PT PT80246A patent/PT80246B/en unknown
- 1985-04-04 OA OA58561A patent/OA07985A/en unknown
- 1985-04-04 CH CH1498/85A patent/CH669197A5/en not_active IP Right Cessation
- 1985-04-04 GB GB08508846A patent/GB2157293B/en not_active Expired
- 1985-04-05 LU LU85840A patent/LU85840A1/en unknown
- 1985-04-05 FR FR8505281A patent/FR2563832B1/en not_active Expired
- 1985-04-05 AT AT0103985A patent/AT388735B/en not_active IP Right Cessation
- 1985-04-05 IT IT20267/85A patent/IT1190353B/en active
- 1985-04-05 IL IL74826A patent/IL74826A/en not_active IP Right Cessation
- 1985-04-08 GR GR850883A patent/GR850883B/el not_active IP Right Cessation
- 1985-04-08 ES ES542013A patent/ES8607318A1/en not_active Expired
- 1985-04-08 RU SU853878102A patent/RU2056425C1/en active
- 1985-04-09 BE BE0/214810A patent/BE902148A/en not_active IP Right Cessation
- 1985-04-09 KR KR1019850002383A patent/KR870002166B1/en not_active IP Right Cessation
- 1985-04-09 HU HU851299A patent/HU193750B/en unknown
- 1985-04-09 JP JP60075233A patent/JPS615084A/en active Granted
- 1985-04-09 YU YU60085A patent/YU46151B/en unknown
- 1985-04-09 HU HU87151A patent/HU204277B/en unknown
- 1985-11-12 JP JP60252139A patent/JPS61143391A/en active Granted
- 1985-11-12 JP JP60252138A patent/JPS61143390A/en active Granted
- 1985-11-12 JP JP60252140A patent/JPS61143387A/en active Granted
1986
- 1986-01-31 ES ES551550A patent/ES8706155A1/en not_active Expired
- 1986-01-31 ES ES551551A patent/ES8706694A1/en not_active Expired
- 1986-02-06 SU SU864019975A patent/SU1487814A3/en active
- 1986-02-06 SU SU864018257A patent/SU1375140A3/en active
- 1986-02-06 SU SU864023036A patent/SU1367858A3/en active
- 1986-02-06 SU SU864020682A patent/SU1436882A3/en active
- 1986-03-03 DD DD86287525A patent/DD251752A5/en unknown
- 1986-09-10 ES ES557060A patent/ES8800949A1/en not_active Expired
1987
- 1987-06-25 YU YU118987A patent/YU46213B/en unknown
- 1987-09-10 GB GB08721346A patent/GB2194789B/en not_active Expired
- 1987-09-10 GB GB08721347A patent/GB2194790B/en not_active Expired
- 1987-10-01 MY MYPI87002761A patent/MY101940A/en unknown
1988
- 1988-11-11 AU AU25041/88A patent/AU610278B2/en not_active Expired
1989
- 1989-04-04 IE IE121089A patent/IE58403B1/en not_active IP Right Cessation
- 1989-04-06 SE SE8901224A patent/SE470259B/en not_active IP Right Cessation
- 1989-04-06 SE SE8901225A patent/SE505256C2/en not_active IP Right Cessation
- 1989-04-06 SE SE8901226A patent/SE470260B/en not_active IP Right Cessation
1991
- 1991-08-12 CA CA000616143A patent/CA1340638C/en not_active Expired - Fee Related
- 1991-08-21 CA CA000616144A patent/CA1340672C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
OA07985A (en)	1987-01-31
KR850007424A (en)	1985-12-04
AU580990B2 (en)	1989-02-09
ES551551A0 (en)	1987-07-01
CA1276929C (en)	1990-11-27
AU4086285A (en)	1985-10-17
ES8607318A1 (en)	1986-06-16
NL192925C (en)	1998-05-07
NL192925B (en)	1998-01-05
SU1375140A3 (en)	1988-02-15
JPH0350754B2 (en)	1991-08-02
FR2563832B1 (en)	1989-08-18
SE8901226D0 (en)	1989-04-06
PT80246B (en)	1987-10-20
GB2157293B (en)	1988-10-05
IE850866L (en)	1985-10-09
JPS61143391A (en)	1986-07-01
JPS61143387A (en)	1986-07-01
GB2194789A (en)	1988-03-16
CA1340638C (en)	1999-07-06
JPS61143390A (en)	1986-07-01
SE8901224L (en)	1989-04-06
CH669197A5 (en)	1989-02-28
SE470259B (en)	1993-12-20
GB2194789B (en)	1988-10-12
HUT37622A (en)	1986-01-23
GB2194790A (en)	1988-03-16
ZA852236B (en)	1985-11-27
AU2504188A (en)	1989-03-02
AR244694A1 (en)	1993-11-30
IL74826A (en)	1990-01-18
DK155985A (en)	1985-10-10
NL8501002A (en)	1985-11-01
GB8721346D0 (en)	1987-10-14
SE8501680L (en)	1985-10-10
ATA103985A (en)	1989-01-15
JPS615084A (en)	1986-01-10
ES542013A0 (en)	1986-06-16
GB2157293A (en)	1985-10-23
SE8901225L (en)	1989-04-06
JPH0351716B2 (en)	1991-08-07
DD251752A5 (en)	1987-11-25
PT80246A (en)	1985-05-01
HU204277B (en)	1991-12-30
ES8706155A1 (en)	1987-06-01
DD249024A5 (en)	1987-08-26
IE58408B1 (en)	1993-09-22
SE8501680D0 (en)	1985-04-03
JPH0357106B2 (en)	1991-08-30
IL74826A0 (en)	1985-07-31
YU46213B (en)	1993-05-28
YU60085A (en)	1987-12-31
DE3512225C2 (en)	1990-02-22
FI84830B (en)	1991-10-15
GB8508846D0 (en)	1985-05-09
DK155985D0 (en)	1985-04-03
SE8901225D0 (en)	1989-04-06
YU46151B (en)	1993-05-28
GB2194790B (en)	1988-10-05
AU610278B2 (en)	1991-05-16
FI84830C (en)	1992-01-27
MY101940A (en)	1992-02-15
SE466205B (en)	1992-01-13
IT8520267A0 (en)	1985-04-05
FR2563832A1 (en)	1985-11-08
DD236735A5 (en)	1986-06-18
BE902148A (en)	1985-10-09
SU1487814A3 (en)	1989-06-15
GR850883B (en)	1985-11-25
SU1436882A3 (en)	1988-11-07
ES557060A0 (en)	1987-12-01
RU2056425C1 (en)	1996-03-20
FI851379A0 (en)	1985-04-04
HU193750B (en)	1987-11-30
SE8901226L (en)	1989-04-06
ES8706694A1 (en)	1987-07-01
JPH0262557B2 (en)	1990-12-26
SE505256C2 (en)	1997-07-21
DE3512225A1 (en)	1985-10-17
LU85840A1 (en)	1985-12-16
CA1340672C (en)	1999-07-20
ES551550A0 (en)	1987-06-01
ES8800949A1 (en)	1987-12-01
YU118987A (en)	1988-10-31
KR870002166B1 (en)	1987-12-14
AT388735B (en)	1989-08-25
SE8901224D0 (en)	1989-04-06
FI851379L (en)	1985-10-10
NZ211659A (en)	1988-11-29
IE58403B1 (en)	1993-09-22
SE470260B (en)	1993-12-20
GB8721347D0 (en)	1987-10-14
SU1367858A3 (en)	1988-01-15

Publication	Publication Date	Title
IT8521651A0 (en)	1985-07-19	ANTIBACTERIAL NUTRIENT COMPOSITIONS FOR ANIMALS AND PROCEDURE FOR THEIR PREPARATION.
IT1190353B (en)	1988-02-16	CEFEM COMPOUNDS WITH ANTIBACTERIAL ACTIVITY, RELATED PREPARATION AND INTERMEDIATE PROCEDURE FOR THIS
IT1196237B (en)	1988-11-16	HEROCICLIC COMPOUNDS WITH HERBICIDE ACTIVITY
IT1196348B (en)	1988-11-16	COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY
IT8419790A0 (en)	1984-02-24	PYRIDO-BENZOTHIAZINE DERIVATIVES WITH HIGH ANTIMICROBIAL ACTIVITY.
IT8721063A0 (en)	1987-06-26	COMPOSITION WITH TRICHOGENIC ACTIVITY.
IT8421241A0 (en)	1984-06-04	COMPOUNDS WITH ANTIBACTERIAL ACTIVITY, PROCEDURE FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS.
IT8721990A0 (en)	1987-09-23	COMPOSITION FOR TOPICAL USE HAVING TRICHOGENIC, ANTIDANDRUFF AND ANTISEBORRHEA ACTIVITY.
IT8621194A0 (en)	1986-07-21	AZOLIL DERIVATIVES WITH ANTIFUNGAL ACTIVITY.
NZ219949A (en)	1990-07-26	Cyanoacetamido derivatives having fungicidal activity, fungicidal compositions and intermediate compounds
IT8420075A0 (en)	1984-03-16	COMPOUNDS WITH ANTIBACTERIAL ACTIVITY.
IT8522424A0 (en)	1985-10-10	COMPOUND WITH PILOSTIMULANT ACTIVITY.
IT8420466A0 (en)	1984-04-10	COMPOUNDS WITH CARDIOTROPHIC ACTIVITY.
IT8125298A0 (en)	1981-11-26	COMPOUND WITH ANTI-INFLAMMATORY, DISINFECTANT AND ANTIBACTERIAL ACTIVITY, PROCEDURE FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS.
IT8419683A0 (en)	1984-02-17	COMPOUNDS WITH HYPE-LOWER ACTIVITY.
IT8419682A0 (en)	1984-02-17	COMPOUNDS WITH HYPE-LOWER ACTIVITY.
IT8520653A0 (en)	1985-05-10	COMPOUNDS WITH ANTIBACTERIAL ACTIVITY, THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS.
IT8422176A0 (en)	1984-08-01	COMPOUND WITH ANTIBACTERIAL ACTIVITY, PROCEDURE FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS.
IT8423770A0 (en)	1984-11-28	COMPOUNDS WITH ANTIBACTERIAL ACTIVITY, PROCEDURE FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS.
IT8520514A0 (en)	1985-04-26	COMPOSITIONS OF DRUG EQUIPPED WITH ANTIMICROBIAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION.
IT8419929A0 (en)	1984-03-07	NEW PROCEDURES FOR THE PREPARATION OF COMPOUND WITH ANTI-ULCERA ACTIVITY.
IT8424156A0 (en)	1984-12-20	COMPOUNDS WITH ANTIBACTERIAL ACTIVITY, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
IT8423796A0 (en)	1984-11-29	COMPOUND WITH ANTIMICROBIAL ACTIVITY, ITS PREPARATION AND PHARMACEUTICAL FORMS THAT CONTAIN IT.
IT8422006A0 (en)	1984-07-23	COMPOUND WITH PHARMACOLOGICAL ACTIVITY, PROCEDURE FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS.
IT8125279A0 (en)	1981-11-25	COMPOUND WITH ANTIBACTERIAL ACTIVITY, PROCEDURE FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970429