IT1175508B - Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta - Google Patents

Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta

Info

Publication number: IT1175508B
Authority: IT; Italy
Prior art keywords: protein; polideoxyribonucleotide; segment; procedure; produce
Prior art date: 1983-06-23

Application number

IT21436/84A

Other languages

English (en)

Other versions

IT8421436A1 (it

IT8421436A0 (it

Inventor

Annette Elmblad

Gunnar Palm

Staffan Josephson

Larl Olof Heden

Erik Holmgren

Original Assignee

Kabigen Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-06-23

Filing date

1984-06-15

Publication date

1987-07-01

1984-06-15 Application filed by Kabigen Ab filed Critical Kabigen Ab

1984-06-15 Publication of IT8421436A0 publication Critical patent/IT8421436A0/it

1985-12-15 Publication of IT8421436A1 publication Critical patent/IT8421436A1/it

1987-07-01 Application granted granted Critical

1987-07-01 Publication of IT1175508B publication Critical patent/IT1175508B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Zoology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Crystallography & Structural Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)

IT21436/84A 1983-06-23 1984-06-15 Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta IT1175508B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8303626A SE8303626D0 (sv)	1983-06-23	1983-06-23	A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced

Publications (3)

Publication Number	Publication Date
IT8421436A0 IT8421436A0 (it)	1984-06-15
IT8421436A1 IT8421436A1 (it)	1985-12-15
IT1175508B true IT1175508B (it)	1987-07-01

Family

ID=20351747

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT21436/84A IT1175508B (it)	1983-06-23	1984-06-15	Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta

Country Status (5)

Country	Link
EP (1)	EP0130166A1 (it)
JP (1)	JPS6019493A (it)
GB (1)	GB2142033A (it)
IT (1)	IT1175508B (it)
SE (1)	SE8303626D0 (it)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL71991A (en) *	1983-06-06	1994-05-30	Genentech Inc	Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
WO1985000831A1 (en) *	1983-08-10	1985-02-28	Amgen	Microbial expression of insulin-like growth factor
DK108685A (da) *	1984-03-19	1985-09-20	Fujisawa Pharmaceutical Co	Vaekstfaktor i
GB8522977D0 (en) *	1985-09-17	1985-10-23	Fujisawa Pharmaceutical Co	Production of insulin-like growth factor 1
US4738921A (en) *	1984-09-27	1988-04-19	Eli Lilly And Company	Derivative of the tryptophan operon for expression of fused gene products
GB8507833D0 (en) *	1985-03-26	1985-05-01	Biogen Nv	Production of human somatomedin c
ES2029785T3 (es) *	1985-10-21	1992-10-01	Fujisawa Pharmaceutical Co., Ltd.	Procedimiento para producir factor de crecimiento tipo insulina i y plasmido para su produccion.
JPH0817708B2 (ja) *	1986-10-09	1996-02-28	藤沢薬品工業株式会社	Ｍｅｔ−インスリン様成長因子Ｉの発現ベクター
AU3869289A (en) *	1988-07-14	1990-02-05	Baylor College Of Medicine	Solid phase assembly and reconstruction of biopolymers
ATE143696T1 (de) *	1989-02-28	1996-10-15	Canon Kk	Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung
JP2682738B2 (ja) *	1989-06-09	1997-11-26	グロペッププロプライエタリーリミテッド	成長ホルモン融合蛋白質
KR920003787B1 (ko) *	1990-03-05	1992-05-14	한국과학기술 연구원	신규 플라스미드 제조 및 그를 함유한 균주를 배양하여 아이 지 에프-1(igf-1)을 생산하는 방법
US5288931A (en) *	1991-12-06	1994-02-22	Genentech, Inc.	Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
WO1993019084A1 (en) *	1992-03-24	1993-09-30	Synergen, Inc.	Refolding and purification of insulin-like growth factor i
US5663304A (en) *	1993-08-20	1997-09-02	Genentech, Inc.	Refolding of misfolded insulin-like growth factor-I
DE19940749A1 (de)	1998-08-28	2000-05-18	Febit Ferrarius Biotech Gmbh	Verfahren und Vorrichtung zur integrierten Synthese und Analyse von Polymeren
ATE334197T1 (de) *	1999-02-19	2006-08-15	Febit Biotech Gmbh	Verfahren zur herstellung von polymeren
ES2394482T3 (es)	2005-05-02	2013-02-01	Genzyme Corporation	Terapia génica para trastornos de la médula espinal
ES2887076T3 (es)	2005-05-02	2021-12-21	Genzyme Corp	Terapia génica para trastornos neurometabólicos
AR059088A1 (es) *	2006-01-20	2008-03-12	Genzyme Corp	Administracion intraventricular de una proteina para esclerosis lateral amiotrofica
AR059089A1 (es)	2006-01-20	2008-03-12	Genzyme Corp	Administracion intraventricular de una enzima para enfermedades de almacenamiento lisosomal
MX361816B (es)	2006-02-09	2018-12-17	Genzyme Corp	Suministro intraventricular lento.
ES2596885T3 (es)	2006-06-07	2017-01-12	Genzyme Corporation	Terapia génica para esclerosis lateral amiotrófica y otros trastornos de la medula espinal
CN101528922A (zh)	2006-10-03	2009-09-09	建新公司	肌萎缩性侧索硬化症和其它脊髓病症的基因治疗

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ201918A (en) *	1981-09-18	1987-04-30	Genentech Inc	N-terminal methionyl analogues of bovine growth hormone

1983
- 1983-06-23 SE SE8303626A patent/SE8303626D0/xx unknown
1984
- 1984-06-15 IT IT21436/84A patent/IT1175508B/it active
- 1984-06-20 EP EP84850197A patent/EP0130166A1/en not_active Withdrawn
- 1984-06-22 JP JP59129038A patent/JPS6019493A/ja active Pending
- 1984-06-22 GB GB08416007A patent/GB2142033A/en not_active Withdrawn

Also Published As

Publication number	Publication date
GB8416007D0 (en)	1984-07-25
IT8421436A1 (it)	1985-12-15
GB2142033A (en)	1985-01-09
EP0130166A1 (en)	1985-01-02
IT8421436A0 (it)	1984-06-15
JPS6019493A (ja)	1985-01-31
SE8303626D0 (sv)	1983-06-23

Publication	Publication Date	Title
IT1175508B (it)	1987-07-01	Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta
DK151985A (da)	1985-10-07	Humant fysiologisk aktivt polypeptid
IT8619338A0 (it)	1986-02-07	Peptide sintetico ad attivita'interleukina 1 umana.
IT8423173A0 (it)	1984-10-16	Dipeptidi ad attivita'farmacologica.
TR25164A (tr)	1992-10-27	INTEKTISID ÖZELLIKTE N'-SüBSTITüENTLI-N,N-DIACIL- HIDRAZINLER
DE58908574D1 (de)	1994-12-08	Elektrode.
IT8722816A0 (it)	1987-11-30	Unita' pompante.
EP0129582A4 (en)	1987-09-02	BIOLOGICALLY ACTIVE PEPTIDES AND PROTEINS FOR ORAL ADMINISTRATION.
ES510078A0 (es)	1983-01-16	"perfeccionamientos en pulverizadores ultrasonicos".
IT8521468A0 (it)	1985-07-08	Procedimento per ottenere interferon leucocitario alfa-2dell'uomo.
NO902791D0 (no)	1990-06-22	Proteinhydrolyse.
IT8819791A0 (it)	1988-03-16	Peptidi ad attivita' farmaceutica.
FI841649A0 (fi)	1984-04-26	Biologiskt aktiva polypeptider.
FI895456A0 (fi)	1989-11-16	Rekombinant interleukin 2-hybridproteiner.
DE3481420D1 (de)	1990-04-05	Physiologisch aktives proteinmaterial.
DK93683D0 (da)	1983-02-25	Biologisk aktive peptider
IT1188645B (it)	1988-01-20	Tripeptide ad attivita' immunostimolante
IT1152126B (it)	1986-12-31	Procedimento e dispositivo per consentire ad un automobilista di orientarsi, specialmente in una citta'
IT1188646B (it)	1988-01-20	Tripeptide ad attivita' immunostimolante
FR2578255B1 (fr)	1989-01-06	Acides 8-oxo-2-oxa-1-azabicyclo(4.2.0)octane-3-carboxyliques a action therapeutique
DE3869939D1 (de)	1992-05-14	Biologisch wirksame peptide.
IT1214444B (it)	1990-01-18	Peptidi biologicamente attivi.
FR2666393B1 (fr)	1995-03-17	Garniture d'etancheite.
IT1238207B (it)	1993-07-12	Preparato vitaminizzato contenente l'enzima lisozima impiegabile in zootecnica e procedimento per la sua produzione.
IT8819790A0 (it)	1988-03-16	Peptidi ad attivita' farmaceutica.

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970628