IN2015DN01408A - - Google Patents
Info
- Publication number
- IN2015DN01408A IN2015DN01408A IN1408DEN2015A IN2015DN01408A IN 2015DN01408 A IN2015DN01408 A IN 2015DN01408A IN 1408DEN2015 A IN1408DEN2015 A IN 1408DEN2015A IN 2015DN01408 A IN2015DN01408 A IN 2015DN01408A
- Authority
- IN
- India
- Prior art keywords
- compounds
- present
- relates
- pi3k
- mtor pathway
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1408DEN2015 IN2015DN01408A (hr) | 2012-07-23 | 2013-07-23 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2283DE2012 | 2012-07-23 | ||
| IN1408DEN2015 IN2015DN01408A (hr) | 2012-07-23 | 2013-07-23 | |
| PCT/IN2013/000458 WO2014016849A2 (en) | 2012-07-23 | 2013-07-23 | Novel triazine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015DN01408A true IN2015DN01408A (hr) | 2015-07-03 |
Family
ID=54187091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1408DEN2015 IN2015DN01408A (hr) | 2012-07-23 | 2013-07-23 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9630958B2 (hr) |
| EP (1) | EP2874632B1 (hr) |
| JP (1) | JP6175139B2 (hr) |
| CN (1) | CN104582707B (hr) |
| IN (1) | IN2015DN01408A (hr) |
| WO (1) | WO2014016849A2 (hr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017009751A1 (en) * | 2015-07-15 | 2017-01-19 | Pfizer Inc. | Pyrimidine derivatives |
| ES2775775T3 (es) * | 2016-09-13 | 2020-07-28 | Covestro Deutschland Ag | Uso de un polímero elástico para la producción de un cuerpo poroso en un procedimiento de fabricación aditiva |
| CN110312709A (zh) * | 2016-11-01 | 2019-10-08 | 斯法尔制药私人有限公司 | 包含表儿茶素和抗癌化合物的组合的组合物 |
| CN106749081B (zh) * | 2016-11-21 | 2019-06-25 | 浙江嘉圣生物医药有限公司 | 一种(s)-(4-溴-2-甲苯)(3-甲基吗啉)甲酮的制备方法 |
| CN107266422A (zh) * | 2017-06-12 | 2017-10-20 | 西安交通大学 | 2‑（5‑嘧啶基）‑4‑吗啉基‑6‑取代均三嗪类化合物及其盐、制备方法和应用 |
| US20200199136A1 (en) * | 2017-08-28 | 2020-06-25 | Acurastem Inc. | Pikfyve kinase inhibitors |
| CN109810100B (zh) * | 2017-11-21 | 2022-03-11 | 中国药科大学 | 含有苯并呋喃的parp-1和pi3k双靶点抑制剂 |
| CN108586446A (zh) * | 2018-04-20 | 2018-09-28 | 湖南华腾制药有限公司 | 三嗪类化合物及其制备方法和抗肿瘤应用 |
| CA3204318A1 (en) | 2020-12-17 | 2022-06-23 | Astrazeneca Ab | N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-quinoline-4-carboxamides |
| CN113200969B (zh) * | 2021-05-19 | 2022-11-25 | 中国药科大学 | 一种PI3Kα选择性抑制剂及其制备方法和应用 |
| CN116239580A (zh) * | 2023-03-06 | 2023-06-09 | 中国药科大学 | 三嗪类化合物及其制备方法、药物组合物和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006503043A (ja) * | 2002-09-10 | 2006-01-26 | サイオス インク． | ＴＧＦβ阻害剤 |
| JO2660B1 (en) * | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
| WO2009066084A1 (en) * | 2007-11-21 | 2009-05-28 | F. Hoffmann-La Roche Ag | 2 -morpholinopyrimidines and their use as pi3 kinase inhibitors |
| AP2010005452A0 (en) | 2008-05-23 | 2010-12-31 | Wyeth Llc | Triazine compounds as P13 kinase and MTOR inhibitors. |
| GB2465405A (en) * | 2008-11-10 | 2010-05-19 | Univ Basel | Triazine, pyrimidine and pyridine analogues and their use in therapy |
| ES2706185T3 (es) | 2009-07-07 | 2019-03-27 | Mei Pharma Inc | Pirimidinil y 1,3,5-triazinil bencimidazoles y sus usos en la terapia contra el cáncer |
| US9481670B2 (en) * | 2011-01-25 | 2016-11-01 | Sphaera Pharma Pte. Ltd. | Triazine compounds |
-
2013
- 2013-07-23 CN CN201380044355.4A patent/CN104582707B/zh active Active
- 2013-07-23 EP EP13823590.8A patent/EP2874632B1/en active Active
- 2013-07-23 JP JP2015523659A patent/JP6175139B2/ja not_active Expired - Fee Related
- 2013-07-23 WO PCT/IN2013/000458 patent/WO2014016849A2/en active Application Filing
- 2013-07-23 IN IN1408DEN2015 patent/IN2015DN01408A/en unknown
- 2013-07-23 US US14/416,140 patent/US9630958B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN104582707B (zh) | 2017-09-26 |
| EP2874632A2 (en) | 2015-05-27 |
| WO2014016849A3 (en) | 2014-06-19 |
| WO2014016849A2 (en) | 2014-01-30 |
| JP2015526424A (ja) | 2015-09-10 |
| US9630958B2 (en) | 2017-04-25 |
| EP2874632B1 (en) | 2020-06-17 |
| US20150197515A1 (en) | 2015-07-16 |
| EP2874632A4 (en) | 2016-03-16 |
| JP6175139B2 (ja) | 2017-08-02 |
| WO2014016849A9 (en) | 2014-03-13 |
| CN104582707A (zh) | 2015-04-29 |
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