IN2014DN10441A - - Google Patents
Info
- Publication number
- IN2014DN10441A IN2014DN10441A IN10441DEN2014A IN2014DN10441A IN 2014DN10441 A IN2014DN10441 A IN 2014DN10441A IN 10441DEN2014 A IN10441DEN2014 A IN 10441DEN2014A IN 2014DN10441 A IN2014DN10441 A IN 2014DN10441A
- Authority
- IN
- India
- Prior art keywords
- cell culture
- culture medium
- preparation
- component
- filtration
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/26—Conditioning fluids entering or exiting the reaction vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0017—Filtration
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
- C12M37/02—Filters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Filtering Materials (AREA)
Abstract
The invention relates to a method for removing a viral contaminant from a preparation being a cell culture medium or at least a component of a cell culture medium. The method comprises subjecting said preparation to filtration for at least about 24 hours through a virus filter having an effective pore size of maximum about 75 nm. Further the invention relates to the use of a virus filter in filtration of at least about 24 hours wherein the virus filter has an effective pore size of maximum about 75 nm for the removal of viral contaminant from a preparation being a cell culture medium or at least a component of a cell culture medium. In some embodiments the filtration according to the invention operates at a volumetric capacity of at least about 2000 L/m2. Further the invention relates to the use of a preparation being a cell culture medium or at least a component of a cell culture medium obtainable according to method of the invention for cell culture; pharmaceutical diagnostic and/or cosmetic preparations as well as in food preparations.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261662814P | 2012-06-21 | 2012-06-21 | |
| PCT/US2013/045663 WO2013192009A1 (en) | 2012-06-21 | 2013-06-13 | Virus filtration of cell culture media |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN10441A true IN2014DN10441A (en) | 2015-08-21 |
Family
ID=48672845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN10441DEN2014 IN2014DN10441A (en) | 2012-06-21 | 2013-06-13 |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US9670456B2 (en) |
| EP (2) | EP3103861B1 (en) |
| JP (3) | JP6220392B2 (en) |
| KR (2) | KR102008048B1 (en) |
| CN (2) | CN108795724A (en) |
| AR (1) | AR092847A1 (en) |
| AU (2) | AU2013277532B2 (en) |
| BR (1) | BR112014031842B1 (en) |
| CA (1) | CA2876473C (en) |
| CO (1) | CO7151484A2 (en) |
| DK (2) | DK2732020T3 (en) |
| EA (2) | EA201990887A1 (en) |
| ES (2) | ES2601429T3 (en) |
| HK (2) | HK1198335A1 (en) |
| HR (1) | HRP20161435T1 (en) |
| HU (1) | HUE031601T2 (en) |
| IL (2) | IL236073B (en) |
| IN (1) | IN2014DN10441A (en) |
| MX (1) | MX347319B (en) |
| MY (2) | MY173835A (en) |
| NZ (1) | NZ629083A (en) |
| PL (2) | PL3103861T3 (en) |
| PT (2) | PT3103861T (en) |
| SG (2) | SG11201408490PA (en) |
| SI (1) | SI2732020T1 (en) |
| TW (2) | TWI609962B (en) |
| WO (1) | WO2013192009A1 (en) |
| ZA (1) | ZA201409253B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201990887A1 (en) * | 2012-06-21 | 2019-08-30 | Баксалта Инкорпорейтид | VIRAL FILTRATION AMONG CELL CULTURES |
| AR095196A1 (en) | 2013-03-15 | 2015-09-30 | Regeneron Pharma | SERUM FREE CELL CULTIVATION MEDIA |
| SG10201507931QA (en) | 2014-12-22 | 2016-07-28 | Emd Millipore Corp | Removal of microorganisms from cell culture media |
| JP7133925B2 (en) | 2015-03-23 | 2022-09-09 | アレクシオン ファーマシューティカルズ インコーポレイテッド | virus filtration |
| EP3015542A1 (en) * | 2015-05-07 | 2016-05-04 | Bayer Technology Services GmbH | Modular system and method for continuous, germ reduced production and/or processing of a product |
| TW202440903A (en) | 2015-08-04 | 2024-10-16 | 美商再生元醫藥公司 | Taurine supplemented cell culture medium and methods of use |
| WO2017180814A1 (en) * | 2016-04-15 | 2017-10-19 | Boehringer Ingelheim International Gmbh | Cell retention device and method |
| CN110225790A (en) * | 2016-12-09 | 2019-09-10 | 龙沙有限公司 | The method for reducing virus titer in drug |
| US20190010531A1 (en) * | 2017-07-06 | 2019-01-10 | Regeneron Pharmaceuticals, Inc. | Cell culture process for making a glycoprotein |
| TWI846694B (en) * | 2018-05-04 | 2024-07-01 | 美商健臻公司 | Perfusion bioreactor with filtration systems |
| CA3132977A1 (en) | 2019-03-11 | 2020-09-17 | Genzyme Corporation | Tangential viral filtration |
| US20230181796A1 (en) * | 2020-05-14 | 2023-06-15 | North Carolina State University | Fast automated approach for the derivation of acellular extracellular matrix scaffolds from tissues |
| JP2023544163A (en) * | 2020-10-02 | 2023-10-20 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Continuous virus capture filtration |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0422874A (en) * | 1990-05-16 | 1992-01-27 | Matsushita Electric Ind Co Ltd | Waveform display device |
| GB2352652A (en) * | 1999-08-06 | 2001-02-07 | Fsm Technologies Ltd | Pre-treating hollow fibre membranes for micro-organism detection |
| US6485686B1 (en) * | 1999-09-17 | 2002-11-26 | The United States Of America As Represented By The Secretary Of The Army | Method and apparatus for counting submicron sized particles |
| US6861001B2 (en) | 1999-12-02 | 2005-03-01 | The General Hospital Corporation | Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon |
| US6485688B1 (en) | 2000-04-24 | 2002-11-26 | General Electric Company | On-line sparging sampling and monitoring systems and methods |
| US6630016B2 (en) * | 2002-01-31 | 2003-10-07 | Koslow Technologies Corp. | Microporous filter media, filtration systems containing same, and methods of making and using |
| US6835311B2 (en) | 2002-01-31 | 2004-12-28 | Koslow Technologies Corporation | Microporous filter media, filtration systems containing same, and methods of making and using |
| ES2214967B1 (en) | 2003-03-06 | 2005-06-16 | Probitas Pharma, S.A | PROCEDURE FOR THE ELIMINATION OF VIRUSES IN FIBRINOGEN AND FIBRINOGEN SOLUTIONS OBTAINED BY SUCH PROCEDURE. |
| CN102351953B (en) * | 2003-12-01 | 2017-05-10 | 诺和诺德医疗保健公司 | Virus filtration of liquid Factor VII compositions |
| DE102005047301B4 (en) * | 2005-09-30 | 2009-04-16 | Sartorius Stedim Biotech Gmbh | Method for detection of virus depletion for the validation of filters and filtration processes |
| US20070084788A1 (en) * | 2005-10-14 | 2007-04-19 | Millipore Corporation | Ultrafiltration membranes and methods of making and use of ultrafiltration membranes |
| US8309029B1 (en) * | 2009-03-26 | 2012-11-13 | The United States Of America As Represented By The Secretary Of The Army | Virus and particulate separation from solution |
| US8945895B2 (en) * | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| EP2467399B2 (en) * | 2009-08-20 | 2023-02-01 | Baxalta Incorporated | Purification of vWF for increased removal of non-lipid enveloped viruses |
| EA201990887A1 (en) * | 2012-06-21 | 2019-08-30 | Баксалта Инкорпорейтид | VIRAL FILTRATION AMONG CELL CULTURES |
-
2013
- 2013-06-13 EA EA201990887A patent/EA201990887A1/en unknown
- 2013-06-13 AU AU2013277532A patent/AU2013277532B2/en active Active
- 2013-06-13 PL PL16181886.9T patent/PL3103861T3/en unknown
- 2013-06-13 EP EP16181886.9A patent/EP3103861B1/en active Active
- 2013-06-13 CN CN201810569534.4A patent/CN108795724A/en active Pending
- 2013-06-13 DK DK13731015.7T patent/DK2732020T3/en active
- 2013-06-13 WO PCT/US2013/045663 patent/WO2013192009A1/en active Application Filing
- 2013-06-13 DK DK16181886.9T patent/DK3103861T3/en active
- 2013-06-13 ES ES13731015.7T patent/ES2601429T3/en active Active
- 2013-06-13 PL PL13731015T patent/PL2732020T3/en unknown
- 2013-06-13 MY MYPI2014003498A patent/MY173835A/en unknown
- 2013-06-13 MX MX2014015950A patent/MX347319B/en active IP Right Grant
- 2013-06-13 CN CN201380032998.7A patent/CN104640969A/en active Pending
- 2013-06-13 BR BR112014031842-5A patent/BR112014031842B1/en active IP Right Grant
- 2013-06-13 NZ NZ629083A patent/NZ629083A/en unknown
- 2013-06-13 SG SG11201408490PA patent/SG11201408490PA/en unknown
- 2013-06-13 KR KR1020157001269A patent/KR102008048B1/en active IP Right Grant
- 2013-06-13 PT PT161818869T patent/PT3103861T/en unknown
- 2013-06-13 CA CA2876473A patent/CA2876473C/en active Active
- 2013-06-13 ES ES16181886T patent/ES2829968T3/en active Active
- 2013-06-13 IN IN10441DEN2014 patent/IN2014DN10441A/en unknown
- 2013-06-13 KR KR1020197022413A patent/KR20190092618A/en not_active Application Discontinuation
- 2013-06-13 MY MYPI2018000283A patent/MY195362A/en unknown
- 2013-06-13 HU HUE13731015A patent/HUE031601T2/en unknown
- 2013-06-13 JP JP2015518459A patent/JP6220392B2/en active Active
- 2013-06-13 SG SG10201701721TA patent/SG10201701721TA/en unknown
- 2013-06-13 PT PT137310157T patent/PT2732020T/en unknown
- 2013-06-13 EA EA201590059A patent/EA033006B1/en not_active IP Right Cessation
- 2013-06-13 SI SI201330369A patent/SI2732020T1/en unknown
- 2013-06-13 EP EP13731015.7A patent/EP2732020B1/en active Active
- 2013-06-19 AR ARP130102198A patent/AR092847A1/en active IP Right Grant
- 2013-06-19 US US13/921,417 patent/US9670456B2/en active Active
- 2013-06-19 TW TW102121710A patent/TWI609962B/en active
- 2013-06-19 TW TW106136343A patent/TWI698522B/en active
-
2014
- 2014-11-19 HK HK14111690.4A patent/HK1198335A1/en unknown
- 2014-12-04 IL IL236073A patent/IL236073B/en active IP Right Grant
- 2014-12-15 ZA ZA2014/09253A patent/ZA201409253B/en unknown
- 2014-12-17 CO CO14277524A patent/CO7151484A2/en unknown
-
2016
- 2016-11-02 HR HRP20161435TT patent/HRP20161435T1/en unknown
-
2017
- 2017-03-27 US US15/470,064 patent/US20170260498A1/en not_active Abandoned
- 2017-05-23 HK HK17105198.0A patent/HK1231502A1/en unknown
- 2017-07-13 JP JP2017137031A patent/JP6557706B2/en not_active Expired - Fee Related
- 2017-09-12 AU AU2017228547A patent/AU2017228547B2/en active Active
-
2018
- 2018-11-14 JP JP2018213613A patent/JP2019022526A/en not_active Withdrawn
- 2018-12-04 IL IL263479A patent/IL263479B/en active IP Right Grant
-
2020
- 2020-03-12 US US16/816,641 patent/US11421202B2/en active Active
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