IN2014DN06738A - - Google Patents
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- Publication number
- IN2014DN06738A IN2014DN06738A IN6738DEN2014A IN2014DN06738A IN 2014DN06738 A IN2014DN06738 A IN 2014DN06738A IN 6738DEN2014 A IN6738DEN2014 A IN 6738DEN2014A IN 2014DN06738 A IN2014DN06738 A IN 2014DN06738A
- Authority
- IN
- India
- Prior art keywords
- ingenol
- angelate
- methods
- preparing
- relates
- Prior art date
Links
- VEBVPUXQAPLADL-POYOOMFHSA-N ingenol Chemical compound C1=C(CO)[C@@H](O)[C@]2(O)[C@@H](O)C(C)=C[C@]32[C@H](C)C[C@H]2C(C)(C)[C@H]2[C@H]1C3=O VEBVPUXQAPLADL-POYOOMFHSA-N 0.000 abstract 2
- VEBVPUXQAPLADL-UHFFFAOYSA-N Ingenol Natural products C1=C(CO)C(O)C2(O)C(O)C(C)=CC32C(C)CC2C(C)(C)C2C1C3=O VEBVPUXQAPLADL-UHFFFAOYSA-N 0.000 abstract 1
- VDJHFHXMUKFKET-UHFFFAOYSA-N Ingenol mebutate Natural products CC1CC2C(C)(C)C2C2C=C(CO)C(O)C3(O)C(OC(=O)C(C)=CC)C(C)=CC31C2=O VDJHFHXMUKFKET-UHFFFAOYSA-N 0.000 abstract 1
- VDJHFHXMUKFKET-WDUFCVPESA-N ingenol mebutate Chemical compound C[C@@H]1C[C@H]2C(C)(C)[C@H]2[C@@H]2C=C(CO)[C@@H](O)[C@]3(O)[C@@H](OC(=O)C(\C)=C/C)C(C)=C[C@]31C2=O VDJHFHXMUKFKET-WDUFCVPESA-N 0.000 abstract 1
- 229960002993 ingenol mebutate Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01003—Triacylglycerol lipase (3.1.1.3)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention relates to methods for preparing ingenol 3 angelate from ingenol or ingenol derivatives.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261590544P | 2012-01-25 | 2012-01-25 | |
| US201261669657P | 2012-07-09 | 2012-07-09 | |
| PCT/EP2013/051431 WO2013110753A1 (en) | 2012-01-25 | 2013-01-25 | Process for the preparation of ingenol-3-angelate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN06738A true IN2014DN06738A (en) | 2015-05-22 |
Family
ID=48045413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN6738DEN2014 IN2014DN06738A (en) | 2012-01-25 | 2013-01-25 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9404131B2 (en) |
| EP (1) | EP2807263A1 (en) |
| CN (1) | CN104395477B (en) |
| AU (1) | AU2013203066B2 (en) |
| IN (1) | IN2014DN06738A (en) |
| WO (1) | WO2013110753A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN2014DN06738A (en) | 2012-01-25 | 2015-05-22 | Leo Pharma As | |
| US9758464B2 (en) | 2014-05-23 | 2017-09-12 | Alphora Research Inc. | Continuous flow process for the preparation of Ingenol-3-mebutate |
| WO2016191837A1 (en) * | 2015-06-03 | 2016-12-08 | Amazônia Fitomedicamentos Ltda. | Method for preparing ingenol-3-hexanoate, method for preparing 3-ethynyl-3-hydroxy-4,7,7-trimethylbicyclo[4.1.0]heptane-2-carbaldehyde, and method for preparing the compound 2,2-dimethyl-4-ethynyl-5-triphenylphosphorus anylidene-1,3-dioxane |
| WO2016191836A1 (en) * | 2015-06-03 | 2016-12-08 | Amazônia Fitomedicamentos Ltda. | Method for preparing ingenol-3-dodecanoate, method for preparing 3-ethynyl-3-hydroxy-4,7,7-trimethylbicyclo[4.1.0]heptane-2-carbaldehyde, and method for preparing 2,2-dimethyl-4-ethynyl-5-triphenylphosphorus anylidene-1,3-dioxane |
| CN107836087A (en) * | 2015-07-31 | 2018-03-23 | 华为技术有限公司 | Wave beam training method and device under a kind of multi-user scene |
| KR20170044994A (en) * | 2015-10-16 | 2017-04-26 | 삼성전자주식회사 | Apparatus and method for performing beam forming operation in millileter wave communication system |
| CN107510651A (en) * | 2016-06-17 | 2017-12-26 | 王成 | A kind of nano target preparation preparation of small molecule immune medicine and application thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2586975C2 (en) | 2010-07-20 | 2016-06-10 | Лео Лэборетериз Лимитед | Method of producing ingenol-3-angelate |
| IN2014DN06738A (en) | 2012-01-25 | 2015-05-22 | Leo Pharma As |
-
2013
- 2013-01-25 IN IN6738DEN2014 patent/IN2014DN06738A/en unknown
- 2013-01-25 EP EP13713756.8A patent/EP2807263A1/en not_active Withdrawn
- 2013-01-25 AU AU2013203066A patent/AU2013203066B2/en not_active Ceased
- 2013-01-25 CN CN201380006809.9A patent/CN104395477B/en not_active Expired - Fee Related
- 2013-01-25 WO PCT/EP2013/051431 patent/WO2013110753A1/en active Application Filing
-
2014
- 2014-07-25 US US14/341,720 patent/US9404131B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20150024443A1 (en) | 2015-01-22 |
| WO2013110753A1 (en) | 2013-08-01 |
| US9404131B2 (en) | 2016-08-02 |
| CN104395477A (en) | 2015-03-04 |
| CN104395477B (en) | 2018-09-11 |
| EP2807263A1 (en) | 2014-12-03 |
| AU2013203066B2 (en) | 2016-04-21 |
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