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IN2014DN01619A - - Google Patents

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Publication number
IN2014DN01619A
IN2014DN01619A IN1619DEN2014A IN2014DN01619A IN 2014DN01619 A IN2014DN01619 A IN 2014DN01619A IN 1619DEN2014 A IN1619DEN2014 A IN 1619DEN2014A IN 2014DN01619 A IN2014DN01619 A IN 2014DN01619A
Authority
IN
India
Prior art keywords
relates
present
bisbenzonitrile
triazol
medicaments
Prior art date
Application number
Inventor
Ann Taylor
Lloyd B Klickstein
Jeewan Thakur
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46846026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2014DN01619(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IN2014DN01619A publication Critical patent/IN2014DN01619A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833Encapsulating processes; Filling of capsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/485Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to low dose pharmaceutical compositions comprising the aromatase inhibitor 4 4 [fluoro (1 H 1 2 4 triazol 1 yl)methylene]bisbenzonitrile as the active ingredient in a suitable carrier. The present invention also relates to a process for their preparation and to their use as medicaments.
IN1619DEN2014 2011-09-08 2012-09-06 IN2014DN01619A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161532459P 2011-09-08 2011-09-08
US201261638588P 2012-04-26 2012-04-26
PCT/US2012/053846 WO2013036563A1 (en) 2011-09-08 2012-09-06 Pharmaceutical compositions comprising an aromatase inhibitor

Publications (1)

Publication Number Publication Date
IN2014DN01619A true IN2014DN01619A (en) 2015-05-15

Family

ID=46846026

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1619DEN2014 IN2014DN01619A (en) 2011-09-08 2012-09-06

Country Status (30)

Country Link
US (4) US9295668B2 (en)
EP (2) EP2753312B1 (en)
JP (2) JP6051467B2 (en)
KR (3) KR20140071358A (en)
CN (2) CN103796644B (en)
AR (1) AR087790A1 (en)
AU (2) AU2012304693B2 (en)
BR (2) BR112014004879B1 (en)
CA (2) CA2846884C (en)
CL (1) CL2014000552A1 (en)
CY (2) CY1118461T1 (en)
DK (2) DK2753313T3 (en)
ES (2) ES2613666T3 (en)
HR (2) HRP20170002T1 (en)
HU (2) HUE031478T2 (en)
IL (1) IL231234A (en)
IN (1) IN2014DN01619A (en)
LT (2) LT2753312T (en)
MX (2) MX360315B (en)
PE (1) PE20141584A1 (en)
PL (2) PL2753313T3 (en)
PT (2) PT2753312T (en)
RU (2) RU2617510C2 (en)
SG (2) SG2014012132A (en)
SI (2) SI2753313T1 (en)
TN (1) TN2014000059A1 (en)
TW (1) TW201316987A (en)
UY (1) UY34315A (en)
WO (2) WO2013036563A1 (en)
ZA (1) ZA201401040B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6051467B2 (en) * 2011-09-08 2016-12-27 メレオ バイオファーマ 2 リミテッド Pharmaceutical composition comprising an aromatase inhibitor
US10324099B2 (en) * 2014-03-26 2019-06-18 The Regents Of The University Of California Ultrasensitive androgen receptor bioassay
PL3166596T3 (en) * 2014-07-07 2018-11-30 Novartis Ag Pharmaceutical dosage forms
GB201614179D0 (en) * 2016-08-19 2016-10-05 Mereo Biopharma 2 Ltd Dosage regimen for the treatment of endometriosis
WO2018165145A1 (en) * 2017-03-08 2018-09-13 Ariad Pharmaceuticals, Inc. Pharmaceutical formulations comprising 5-chloro-n4-[2-(dimethylphosphoryl) phenyl]-n2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl} pyrimidine-2,4-diamine
USD894148S1 (en) * 2018-08-16 2020-08-25 Alibaba Group Holding Limited Information terminal for payment
USD894149S1 (en) * 2018-08-16 2020-08-25 Alibaba Group Holding Limited Information terminal for payment
JP7121999B2 (en) * 2019-09-26 2022-08-19 学校法人九州文化学園 Male hypogonadism therapeutic agent

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749713A (en) 1986-03-07 1988-06-07 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
TW210334B (en) * 1990-12-12 1993-08-01 Ciba Geigy Ag
DE4435368A1 (en) * 1994-09-22 1996-03-28 Schering Ag Use of aromatase inhibitors for the manufacture of a medicament for the treatment of a relative androgen deficiency in men
US5972921A (en) * 1997-12-12 1999-10-26 Hormos Medical Oy Ltd. Use of an aromatase inhibitor in the treatment of decreased androgen to estrogen ratio and detrusor urethral sphincter dyssynergia in men
WO2002002113A1 (en) * 2000-07-05 2002-01-10 Astrazeneca Ab Pharmaceutical combination of an anti-androgen and letrozole for providing an anit-androgenic effect and aromatase inhibition
CA2444932A1 (en) * 2001-04-17 2002-10-24 Ares Trading S.A. Aromatase inhibition to enhance assisted reproduction
US7101573B2 (en) * 2001-09-28 2006-09-05 Mcneil-Pcc, Inc. Simethicone solid oral dosage form
EP1492515A1 (en) * 2002-04-03 2005-01-05 Jencap Research Ltd. Pharmaceutical composition comprising an aromatase inhibitor and an estrogen suitable for hormone replacement therapy for a male
EP1937251A2 (en) 2005-04-25 2008-07-02 Pfizer Products Inc. Pharmaceutical compositions and methods comprising a combination of a selective estrogen receptor modulator and an aromatase inhibitor
JPWO2009066712A1 (en) * 2007-11-21 2011-04-07 クラシエ製薬株式会社 Aromatase inhibitor
JP6051467B2 (en) * 2011-09-08 2016-12-27 メレオ バイオファーマ 2 リミテッド Pharmaceutical composition comprising an aromatase inhibitor

Also Published As

Publication number Publication date
JP2014528932A (en) 2014-10-30
NZ621476A (en) 2016-02-26
CA2846884A1 (en) 2013-03-14
CN103781476B (en) 2016-12-07
HUE031478T2 (en) 2017-07-28
SG2014012132A (en) 2014-06-27
CY1118461T1 (en) 2017-07-12
CN103796644B (en) 2017-05-03
ES2613666T3 (en) 2017-05-25
DK2753313T3 (en) 2017-02-13
EP2753313A1 (en) 2014-07-16
KR20180030254A (en) 2018-03-21
WO2013036562A1 (en) 2013-03-14
US20140213622A1 (en) 2014-07-31
MX2014002773A (en) 2014-06-05
CN103781476A (en) 2014-05-07
TN2014000059A1 (en) 2015-07-01
CA2846884C (en) 2019-04-09
CA2845929C (en) 2018-06-19
ZA201401040B (en) 2015-12-23
PE20141584A1 (en) 2014-11-13
RU2014113334A (en) 2015-10-20
HRP20170003T1 (en) 2017-03-10
AU2012304693B2 (en) 2016-03-31
US9295668B2 (en) 2016-03-29
SG10201607503WA (en) 2016-10-28
AR087790A1 (en) 2014-04-16
KR20140058619A (en) 2014-05-14
HUE031435T2 (en) 2017-07-28
CY1118499T1 (en) 2017-07-12
CN103796644A (en) 2014-05-14
EP2753312A1 (en) 2014-07-16
US10064844B2 (en) 2018-09-04
RU2628808C2 (en) 2017-08-22
MX2014002780A (en) 2014-06-05
KR101872561B1 (en) 2018-06-28
IL231234A0 (en) 2014-04-30
PL2753312T3 (en) 2017-06-30
CA2845929A1 (en) 2013-03-14
IL231234A (en) 2016-12-29
LT2753313T (en) 2017-02-10
EP2753312B1 (en) 2016-12-14
UY34315A (en) 2013-04-30
PL2753313T3 (en) 2017-07-31
BR112014004879B1 (en) 2020-01-28
KR20140071358A (en) 2014-06-11
DK2753312T3 (en) 2017-02-13
BR112014005434B1 (en) 2021-01-05
JP6280501B2 (en) 2018-02-14
AU2012304693A1 (en) 2014-03-13
BR112014005434A2 (en) 2017-04-04
AU2012304694B2 (en) 2016-04-07
ES2613667T3 (en) 2017-05-25
JP2014526465A (en) 2014-10-06
CL2014000552A1 (en) 2014-09-12
US20160346257A1 (en) 2016-12-01
TW201316987A (en) 2013-05-01
EP2753313B1 (en) 2016-12-14
US9370505B2 (en) 2016-06-21
US20140309267A1 (en) 2014-10-16
JP6051467B2 (en) 2016-12-27
HRP20170002T1 (en) 2017-02-24
LT2753312T (en) 2017-01-25
MX360315B (en) 2018-10-29
US9750724B2 (en) 2017-09-05
US20160243084A1 (en) 2016-08-25
SI2753312T1 (en) 2017-10-30
AU2012304694A1 (en) 2014-03-20
MX343902B (en) 2016-11-28
SI2753313T1 (en) 2017-04-26
RU2617510C2 (en) 2017-04-25
BR112014004879A2 (en) 2017-03-14
PT2753312T (en) 2017-02-03
RU2014113575A (en) 2015-10-20
WO2013036563A1 (en) 2013-03-14
PT2753313T (en) 2017-02-02

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