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IL84875A0 - 8-substituted 2-aminotetralins,their preparation and pharmaceutical compositions containing them - Google Patents

8-substituted 2-aminotetralins,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL84875A0
IL84875A0 IL84875A IL8487587A IL84875A0 IL 84875 A0 IL84875 A0 IL 84875A0 IL 84875 A IL84875 A IL 84875A IL 8487587 A IL8487587 A IL 8487587A IL 84875 A0 IL84875 A0 IL 84875A0
Authority
IL
Israel
Prior art keywords
aminotetralins
substituted
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL84875A
Other languages
English (en)
Original Assignee
Troponwerke Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke Gmbh & Co Kg filed Critical Troponwerke Gmbh & Co Kg
Publication of IL84875A0 publication Critical patent/IL84875A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/16—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings
    • C07C211/19—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IL84875A 1986-12-22 1987-12-18 8-substituted 2-aminotetralins,their preparation and pharmaceutical compositions containing them IL84875A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3643899 1986-12-22
DE19873719924 DE3719924A1 (de) 1986-12-22 1987-06-15 8-substituierte 2-aminotetraline

Publications (1)

Publication Number Publication Date
IL84875A0 true IL84875A0 (en) 1988-06-30

Family

ID=25850693

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84875A IL84875A0 (en) 1986-12-22 1987-12-18 8-substituted 2-aminotetralins,their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (3) US4873262A (xx)
EP (1) EP0272534A3 (xx)
JP (1) JP2596956B2 (xx)
KR (1) KR880007432A (xx)
CN (1) CN87101285A (xx)
AU (1) AU613884B2 (xx)
DE (1) DE3719924A1 (xx)
DK (1) DK675787A (xx)
FI (1) FI875598A (xx)
HU (1) HUT46653A (xx)
IL (1) IL84875A0 (xx)
NO (1) NO167282C (xx)
NZ (1) NZ222977A (xx)
PT (1) PT86425B (xx)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177112A (en) * 1983-01-03 1993-01-05 Whitby Research, Inc. Substituted 2-aminotetralins
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
DE3852589T2 (de) * 1987-08-12 1995-08-10 Sanofi Sa Verfahren zur O-Alkylierung von N-(Hydroxy)aralkylphenylethanolamin.
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5214156A (en) * 1988-03-25 1993-05-25 The Upjohn Company Therapeutically useful tetralin derivatives
CA1331191C (en) 1988-03-25 1994-08-02 Bengt Ronny Andersson Therapeutically useful tetralin derivatives
US5162375A (en) * 1988-05-06 1992-11-10 Beecham Group P.L.C. Treatment of neuronal degeneration with 5HT1A agonists
GB8810748D0 (en) * 1988-05-06 1988-06-08 Beecham Wuelfing Gmbh & Co Kg Novel treatment
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins
JP2868897B2 (ja) * 1989-01-09 1999-03-10 ジ・アップジョン・カンパニー ハロゲン置換アミノテトラリン類
ZA901277B (en) * 1989-02-27 1991-10-30 Lilly Co Eli Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes
CA1335106C (en) * 1989-02-27 1995-04-04 John Mehnert Schaus Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
GB8907865D0 (en) * 1989-04-07 1989-05-24 Wyeth John & Brother Ltd Tetrahydroquinoline derivatives
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
US5545755A (en) * 1989-05-31 1996-08-13 The Upjohn Company Therapeutically useful 2-aminotetralin derivatives
CA2051399C (en) * 1989-05-31 2003-12-30 Chiu-Hong Lin Therapeutically useful 2-aminotetralin derivatives
DE3919624A1 (de) * 1989-06-15 1990-12-20 Boehringer Ingelheim Kg Neue 2,5-diaminotetraline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE152708T1 (de) * 1989-07-13 1997-05-15 Upjohn Co (1,2n) und (3,2n)-karbozyklische-2-amino- tetralinderivate
US5486611A (en) * 1989-07-13 1996-01-23 The Upjohn Company Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives
DE3924365A1 (de) * 1989-07-22 1991-01-24 Boehringer Ingelheim Kg 2-amino-7-carbamoyl-1,2,3,4- tetrahydronaphthaline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
AU658134B2 (en) * 1989-12-28 1995-04-06 Virginia Commonwealth University Sigma receptor ligands and the use thereof
HUT57185A (en) * 1990-03-21 1991-11-28 Merrell Dow Pharma Process for producing 8-sulfamil-methylen-2-amino-tetraline derivatives and pharmaceutical compositions containing them
US5194439A (en) * 1990-04-06 1993-03-16 John Wyeth & Brother Limited N-(2,3-dihydro-1,4-benzodioxinyl)-N-substituted aminopyrido-fused cycloalkanes
US5340838A (en) * 1990-05-04 1994-08-23 Eli Lilly And Company Method of inhibiting gastric acid secretion with 2-phenylcyclopropylamines
US5258379A (en) * 1990-05-04 1993-11-02 Eli Lilly And Company Method of inhibiting gastric acid secretion with n-arylpiperazines
US5096908A (en) * 1990-05-04 1992-03-17 Eli Lilly And Company Method of inhibiting gastric acid secretion
EP0471515B1 (en) * 1990-08-15 1997-03-05 Eli Lilly And Company Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes, 3-aminochromanes and 3-aminothiochromanes
US5252586A (en) * 1990-09-28 1993-10-12 The Du Pont Merck Pharmaceutical Company Ether derivatives of alkyl piperidines and pyrrolidines as antipsychotic agents
ATE151419T1 (de) * 1991-02-08 1997-04-15 Lilly Co Eli Ringsubstituierte 2-amino-1,2,3,4- tetrahydronaphthaline
EP0586525B1 (en) * 1991-05-20 1997-04-16 PHARMACIA & UPJOHN COMPANY Carboxamido-(1,2n)-carbocyclic-2-aminotetralin derivatives
JPH06507906A (ja) * 1991-05-20 1994-09-08 ジ・アップジョン・カンパニー カルボキサミド−（３，２ｎ）−カルボサイクリック−２−アミノテトラリン誘導体
EP0591426A4 (en) * 1991-06-27 1996-08-21 Univ Virginia Commonwealth Sigma receptor ligands and the use thereof
US5288749A (en) * 1991-12-20 1994-02-22 Abbott Laboratories Tertiary and secondary amines as alpha-2 antagonists and serotonin uptake inhibitors
FR2686339B1 (fr) * 1992-01-22 1994-03-11 Adir Cie Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5194658A (en) * 1992-03-02 1993-03-16 The Dow Chemical Company Process for making 2-amino-3-methyl-1-naphthalenecarbonitrile
EP0714292A4 (en) * 1993-06-23 1996-10-09 Cambridge Neuroscience Inc SIGMA RECEPTOR LIGANDS AND THEIR USE
GB9315566D0 (en) * 1993-07-28 1993-09-08 Smithkline Beecham Plc Medicaments
FR2711140B1 (fr) * 1993-10-12 1996-01-05 Sanofi Sa 1-Naphtylpyrazole-3-carboxamides substitués actifs sur la neurotensine, leur préparation, les compositions pharmaceutiques en contenant.
GB9420529D0 (en) * 1994-10-12 1994-11-30 Pfizer Ltd Indoles
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
CA2255612A1 (en) * 1996-05-31 1997-12-04 Pharmacia & Upjohn Company Aryl substituted cyclic amines as selective dopamine d3 ligands
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6355674B1 (en) 1997-04-30 2002-03-12 Eli Lilly And Company Aminotetralins as 5-HT1D α Agonists
EP1052982A4 (en) * 1997-04-30 2004-10-06 Lilly Co Eli AMINOTETRALINS AS AGONISTS OF 5-HT 1D $ g (a)?
US20050032873A1 (en) * 2003-07-30 2005-02-10 Wyeth 3-Amino chroman and 2-amino tetralin derivatives
US20100006191A1 (en) * 2008-07-09 2010-01-14 Brush Wellman, Inc. HIGH STRENGTH Be/Cu ALLOYS WITH IMPROVED ELECTRICAL CONDUCTIVITY
DE102010020553A1 (de) 2010-05-14 2011-11-17 Bayer Schering Pharma Aktiengesellschaft Substituierte 8-Alkoxy-2-aminotetralin-Derivate und ihre Verwendung
WO2014012935A1 (de) 2012-07-20 2014-01-23 Bayer Pharma Aktiengesellschaft Substituierte aminoindan- und aminotetralin-carbonsäuren und ihre verwendung
SI2875003T1 (sl) 2012-07-20 2017-03-31 Bayer Pharma Aktiengesellschaft Nove 5-aminotetrahidrokinolin-2-karboksilne kisline in njihova uporaba
CN109422668B (zh) * 2017-08-25 2021-06-22 广州市恒诺康医药科技有限公司 一种长效雷沙吉兰前药及其制备方法和用途
KR20240144177A (ko) 2021-12-29 2024-10-02 바이엘 악티엔게젤샤프트 (5s)-{[2-(4-카르복시페닐)에틸][2-(2-{[3-클로로-4'-(트리플루오로메틸)비페닐-4-일]메톡시}페닐)에틸]아미노}-5,6,7,8-테트라히드로퀴놀린-2-카르복실산및 약학적 활성 화합물로서 사용하기 위한 이의 결정질 형태를 제조하는 방법
WO2023126437A1 (en) 2021-12-29 2023-07-06 Bayer Aktiengesellschaft Treatment of cardiopulmonary disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2846691C2 (de) * 1977-10-27 1983-11-10 Torii & Co., Ltd., Tokyo Amino- oder Guanidino-1,2,3,4-tetrahydro-1-naphthoesäureester, Verfahren z u deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2803582A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
ATE19621T1 (de) * 1981-09-15 1986-05-15 Ici Plc Aminosubstituierte tetraline und verwandte homocyclische verbindungen.
US4598093A (en) * 1982-09-07 1986-07-01 Yoshitomi Pharmaceutical Industries, Ltd. 4-amino-tetrahydro-2-naphthoic acid derivatives
US4510157A (en) * 1982-12-27 1985-04-09 Ayerst, Mckenna & Harrison, Inc. 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives
ES2031855T3 (es) * 1986-07-28 1993-01-01 Whitby Research Incorporated Un metodo para preparar una composicion para reducir la presion intraocular en mamiferos.
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline

Also Published As

Publication number Publication date
AU613884B2 (en) 1991-08-15
JP2596956B2 (ja) 1997-04-02
NO875005D0 (no) 1987-12-01
JPS63190857A (ja) 1988-08-08
FI875598A (fi) 1988-06-23
DK675787D0 (da) 1987-12-21
EP0272534A2 (de) 1988-06-29
AU8302987A (en) 1988-06-30
EP0272534A3 (de) 1989-07-26
DK675787A (da) 1988-06-23
HUT46653A (en) 1988-11-28
PT86425B (pt) 1990-11-20
PT86425A (en) 1988-01-01
NZ222977A (en) 1990-07-26
US4873262A (en) 1989-10-10
NO875005L (no) 1988-06-23
NO167282B (no) 1991-07-15
NO167282C (no) 1991-10-23
DE3719924A1 (de) 1988-06-30
FI875598A0 (fi) 1987-12-18
KR880007432A (ko) 1988-08-27
US5047422A (en) 1991-09-10
CN87101285A (zh) 1988-08-17
US4968679A (en) 1990-11-06

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