IL66433A - Spirothiazolidinyl piperazine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Spirothiazolidinyl piperazine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL66433A
Authority: IL; Israel
Prior art keywords: spirothiazolidinyl; preparation; pharmaceutical compositions; compositions containing; piperazine derivatives
Prior art date: 1981-08-03

Application number

IL66433A

Other languages

English (en)

Other versions

IL66433A0 (en

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-08-03

Filing date

1982-08-01

Publication date

1985-10-31

1982-08-01 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1982-12-31 Publication of IL66433A0 publication Critical patent/IL66433A0/xx

1985-10-31 Publication of IL66433A publication Critical patent/IL66433A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

IL66433A 1981-08-03 1982-08-01 Spirothiazolidinyl piperazine derivatives,their preparation and pharmaceutical compositions containing them IL66433A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/289,351 US4456756A (en)	1981-08-03	1981-08-03	Spirothiazolidinyl piperazine derivatives

Publications (2)

Publication Number	Publication Date
IL66433A0 IL66433A0 (en)	1982-12-31
IL66433A true IL66433A (en)	1985-10-31

Family

ID=23111156

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL66433A IL66433A (en)	1981-08-03	1982-08-01	Spirothiazolidinyl piperazine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (28)

Country	Link
US (1)	US4456756A (el)
JP (1)	JPS5838277A (el)
KR (1)	KR880001737B1 (el)
AT (1)	AT380477B (el)
AU (1)	AU555870B2 (el)
BE (1)	BE894021A (el)
CA (1)	CA1208642A (el)
CH (1)	CH655503B (el)
DE (1)	DE3228992A1 (el)
DK (1)	DK156219C (el)
ES (2)	ES514263A0 (el)
FI (1)	FI76794C (el)
FR (1)	FR2510571B1 (el)
GB (1)	GB2105714B (el)
GR (1)	GR76171B (el)
HU (1)	HU191505B (el)
IE (1)	IE53613B1 (el)
IL (1)	IL66433A (el)
IT (1)	IT1149026B (el)
LU (1)	LU84315A1 (el)
NL (1)	NL8203035A (el)
NZ (1)	NZ201158A (el)
OA (1)	OA07171A (el)
PH (1)	PH18688A (el)
PT (1)	PT75365B (el)
SE (1)	SE453503B (el)
YU (1)	YU44073B (el)
ZA (1)	ZA825481B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61162278A (ja) *	1985-01-09	1986-07-22	Nippon Yakin Kogyo Co Ltd	冷却手段を具えたロ−ラ−電極を含む自走式シ−ム溶接機
US4619930A (en) *	1985-01-16	1986-10-28	Bristol-Myers Company	Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
US4677104A (en) *	1985-05-06	1987-06-30	Bristol-Myers Company	Antipsychotic fused-ring pyridinylpiperazine derivatives
US4784998A (en) *	1987-04-06	1988-11-15	Bristol-Myers Company	1,3,4-oxadiazole pyschotropic compounds
ATE81123T1 (de) *	1987-11-20	1992-10-15	Hoechst Roussel Pharma	3-(4(1-substituierte-4-piperazinyl)butyl>-4thiazolidinone, verfahren zu deren herstellung und ihre anwendung als arzneimittel.
US5801186A (en) *	1987-11-20	1998-09-01	Hoechst Marion Roussel, Inc.	3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
JPH0270878U (el) *	1988-11-21	1990-05-30

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL125835C (el) *	1960-05-24
US3106552A (en) *	1960-07-19	1963-10-08	Geschickter Fund Med Res	Nu-substituted azaspiranes and azaspirane-diones and processes for their preparation
US3200118A (en) *	1961-10-31	1965-08-10	Geschickter Fund Med Res	Spirocyclic hydrazine imides
US3432499A (en) *	1965-04-02	1969-03-11	Geschickter Fund Med Res	Trifluoromethylazaspiranes and azaspirane diones
US3398151A (en) *	1966-02-01	1968-08-20	Mead Johnson & Co	Azaspirodecanediones and azaspiroundecanediones
DE1695410A1 (de) *	1967-04-20	1971-04-08	Merck Patent Gmbh	Verfahren zur Herstellung von 1-(Thiazolyl-5-alkyl)-4-(pyridyl-2)-piperazinen
BE759371A (fr) *	1969-11-24	1971-05-24	Bristol Myers Co	Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) *	1972-12-06	1976-08-24	Mead Johnson & Company	Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
EP0002978B1 (fr) *	1977-12-29	1982-10-06	Synthelabo	Dérivés de thiazolidinedione-2,4, leur préparation et leur application en thérapeutique
FI791926A (fi) *	1978-06-20	1979-12-21	Synthelabo	Fenylpiperazinderivat
US4367335A (en) *	1981-08-03	1983-01-04	Mead Johnson & Company	Thiazolidinylalkylene piperazine derivatives

1981
- 1981-08-03 US US06/289,351 patent/US4456756A/en not_active Expired - Fee Related
1982
- 1982-07-05 NZ NZ201158A patent/NZ201158A/en unknown
- 1982-07-13 AU AU85973/82A patent/AU555870B2/en not_active Ceased
- 1982-07-13 GR GR68740A patent/GR76171B/el unknown
- 1982-07-20 YU YU1585/82A patent/YU44073B/xx unknown
- 1982-07-23 ES ES514263A patent/ES514263A0/es active Granted
- 1982-07-28 FR FR8213176A patent/FR2510571B1/fr not_active Expired
- 1982-07-28 IT IT48901/82A patent/IT1149026B/it active
- 1982-07-29 ZA ZA825481A patent/ZA825481B/xx unknown
- 1982-07-29 NL NL8203035A patent/NL8203035A/nl not_active Application Discontinuation
- 1982-07-30 CA CA000408451A patent/CA1208642A/en not_active Expired
- 1982-07-30 IE IE1851/82A patent/IE53613B1/en unknown
- 1982-07-30 DK DK343782A patent/DK156219C/da not_active IP Right Cessation
- 1982-07-30 FI FI822666A patent/FI76794C/fi not_active IP Right Cessation
- 1982-07-30 PH PH27655A patent/PH18688A/en unknown
- 1982-08-01 IL IL66433A patent/IL66433A/xx unknown
- 1982-08-02 PT PT75365A patent/PT75365B/pt not_active IP Right Cessation
- 1982-08-02 GB GB08222210A patent/GB2105714B/en not_active Expired
- 1982-08-02 CH CH466082A patent/CH655503B/de not_active IP Right Cessation
- 1982-08-02 HU HU822483A patent/HU191505B/hu not_active IP Right Cessation
- 1982-08-02 SE SE8204549A patent/SE453503B/sv not_active IP Right Cessation
- 1982-08-03 LU LU84315A patent/LU84315A1/fr unknown
- 1982-08-03 AT AT0299382A patent/AT380477B/de active
- 1982-08-03 DE DE19823228992 patent/DE3228992A1/de not_active Withdrawn
- 1982-08-03 OA OA57764A patent/OA07171A/xx unknown
- 1982-08-03 KR KR8203481A patent/KR880001737B1/ko active
- 1982-08-03 JP JP57134807A patent/JPS5838277A/ja active Granted
- 1982-08-03 BE BE0/208747A patent/BE894021A/fr not_active IP Right Cessation
1983
- 1983-09-30 ES ES526149A patent/ES8504185A1/es not_active Expired

Also Published As

Publication number	Publication date
IE53613B1 (en)	1988-12-21
FI822666L (fi)	1983-02-04
PH18688A (en)	1985-09-05
YU44073B (en)	1990-02-28
DK156219C (da)	1989-12-04
ES526149A0 (es)	1985-04-16
DK343782A (da)	1983-02-04
FI76794C (fi)	1988-12-12
JPS5838277A (ja)	1983-03-05
FR2510571B1 (fr)	1987-07-10
IL66433A0 (en)	1982-12-31
JPH039912B2 (el)	1991-02-12
CA1208642A (en)	1986-07-29
YU158582A (en)	1985-04-30
FI822666A0 (fi)	1982-07-30
SE8204549L (sv)	1983-02-04
AU8597382A (en)	1983-02-10
IE821851L (en)	1983-02-03
ATA299382A (de)	1985-10-15
AT380477B (de)	1986-05-26
ES8401763A1 (es)	1984-01-01
US4456756A (en)	1984-06-26
CH655503B (el)	1986-04-30
NL8203035A (nl)	1983-03-01
BE894021A (fr)	1983-02-03
GB2105714B (en)	1985-05-15
ES514263A0 (es)	1984-01-01
PT75365A (en)	1982-09-01
GR76171B (el)	1984-08-03
KR840001166A (ko)	1984-03-28
AU555870B2 (en)	1986-10-16
SE453503B (sv)	1988-02-08
IT1149026B (it)	1986-12-03
FR2510571A1 (fr)	1983-02-04
HU191505B (en)	1987-02-27
SE8204549D0 (sv)	1982-08-02
LU84315A1 (fr)	1983-06-07
GB2105714A (en)	1983-03-30
ES8504185A1 (es)	1985-04-16
NZ201158A (en)	1985-12-13
KR880001737B1 (ko)	1988-09-10
IT8248901A0 (it)	1982-07-28
OA07171A (fr)	1984-04-30
FI76794B (fi)	1988-08-31
DK156219B (da)	1989-07-10
DE3228992A1 (de)	1983-02-17
ZA825481B (en)	1983-04-27
PT75365B (en)	1985-11-20

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IL64777A0 (en)	1982-03-31	3-aminopropoxyaryl derivatives,their preparation and pharmaceutical compositions containing them
IL65076A (en)	1984-12-31	3,4-dihydro-5h-2,3-benzo-diazepine derivatives,their preparation and pharmaceutical compositions containing them
IL66408A (en)	1985-12-31	3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL70756A0 (en)	1984-04-30	3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL66434A0 (en)	1982-12-31	Thiazolidinylalkylene piperazine derivatives,their preparation and pharmaceutical compositions containing them
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IL66424A (en)	1985-10-31	3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
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IL66223A0 (en)	1982-11-30	Indole derivatives,their preparation and pharmaceutical compositions containing them
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IL66433A (en)	1985-10-31	Spirothiazolidinyl piperazine derivatives,their preparation and pharmaceutical compositions containing them
DE3380093D1 (en)	1989-07-27	3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
IL73776A (en)	1988-02-29	N-phenyl-1h-tetrazole-5-carboxamide derivatives,their preparation and pharmaceutical compositions containing them
IL68092A0 (en)	1983-06-15	Phenylpiperazine derivatives,their preparation and pharmaceutical compositions containing them