IL45880A - 3-phenyl-1,2-benzisoxyzole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3-phenyl-1,2-benzisoxyzole derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL45880A
Authority: IL; Israel
Prior art keywords: benzisoxyzole; phenyl; derivatives; preparation; pharmaceutical compositions
Prior art date: 1973-10-23

Application number

IL45880A

Other languages

English (en)

Other versions

IL45880A0 (en

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-10-23

Filing date

1974-10-18

Publication date

1979-09-30

1974-10-18 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1974-10-18 Priority to IL52180A priority Critical patent/IL52180A/xx

1974-10-18 Priority to IL52179A priority patent/IL52179A/xx

1974-12-31 Publication of IL45880A0 publication Critical patent/IL45880A0/xx

1979-09-30 Publication of IL45880A publication Critical patent/IL45880A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Rheumatology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL45880A 1973-10-23 1974-10-18 3-phenyl-1,2-benzisoxyzole derivatives,their preparation and pharmaceutical compositions containing them IL45880A (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
IL52180A IL52180A (en)	1973-10-23	1974-10-18	Process for preparing a 5-or 6- substituted 2-phenylbenzoxazole
IL52179A IL52179A (en)	1973-10-23	1974-10-18	Benzophenone oximes and hydrazones and their preparation

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB49259/73A GB1488003A (en)	1973-10-23	1973-10-23	1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals

Publications (2)

Publication Number	Publication Date
IL45880A0 IL45880A0 (en)	1974-12-31
IL45880A true IL45880A (en)	1979-09-30

Family

ID=10451720

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
IL45880A IL45880A (en)	1973-10-23	1974-10-18	3-phenyl-1,2-benzisoxyzole derivatives,their preparation and pharmaceutical compositions containing them
IL52179A IL52179A0 (en)	1973-10-23	1977-05-27	Novel benzophenone oximes and hydrazones and their preparation
IL52180A IL52180A0 (en)	1973-10-23	1977-05-27	Process for preparing a 5-or 6-substituted benzoxazole

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
IL52179A IL52179A0 (en)	1973-10-23	1977-05-27	Novel benzophenone oximes and hydrazones and their preparation
IL52180A IL52180A0 (en)	1973-10-23	1977-05-27	Process for preparing a 5-or 6-substituted benzoxazole

Country Status (27)

Country	Link
US (1)	US3951999A (xx)
JP (2)	JPS5912671B2 (xx)
AR (3)	AR209755A1 (xx)
AT (1)	AT341520B (xx)
AU (1)	AU510909B2 (xx)
BE (1)	BE821406A (xx)
BG (2)	BG25991A3 (xx)
CA (1)	CA1042005A (xx)
CH (2)	CH595360A5 (xx)
CS (1)	CS189671B2 (xx)
DD (1)	DD116830A5 (xx)
DE (1)	DE2450053A1 (xx)
DK (1)	DK552674A (xx)
ES (3)	ES431247A1 (xx)
FR (3)	FR2248041B1 (xx)
GB (1)	GB1488003A (xx)
HU (1)	HU171613B (xx)
IE (1)	IE40078B1 (xx)
IL (3)	IL45880A (xx)
NL (1)	NL7413848A (xx)
NZ (1)	NZ175780A (xx)
PH (1)	PH11022A (xx)
RO (2)	RO74031A (xx)
SE (3)	SE424324B (xx)
SU (3)	SU604491A3 (xx)
YU (1)	YU282474A (xx)
ZA (1)	ZA746594B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1590587A (en) *	1977-06-28	1981-06-03	Lilly Industries Ltd	Benoxaprofen
US4673746A (en) *	1978-10-06	1987-06-16	Hoechst-Roussel Pharmaceuticals, Inc.	1,2-benzisoxazoloxyacetic acids and related compounds
US4728662A (en) *	1977-11-21	1988-03-01	Hoechst-Roussel Pharmaceuticals Inc.	1,2-benzisoxazoloxyacetic acids and related compounds
NZ189705A (en) *	1978-03-01	1981-07-13	Boots Co Ltd	Benzophenone-hydrazone derivatives and pesticidal compositions intermediates
US4337261A (en) *	1980-07-28	1982-06-29	Hoechst-Roussel Pharmaceuticals Inc.	(1,2-Benzisoxazol)phenoxyacetic acids as diuretics
US4894461A (en) *	1981-04-27	1990-01-16	Hoechst-Roussel Pharmaceuticals, Inc.	3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole
US4396770A (en) *	1982-04-09	1983-08-02	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines
US4536578A (en) *	1982-04-09	1985-08-20	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4610988A (en) *	1982-04-09	1986-09-09	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain
US4609658A (en) *	1982-04-09	1986-09-02	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure
US4374245A (en) *	1982-04-09	1983-02-15	Hoechst-Roussel Pharmaceuticals Inc.	8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
US4458075A (en) *	1982-04-09	1984-07-03	Hoechst-Roussel Pharmaceuticals Inc.	6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles
US4390544A (en) *	1982-04-09	1983-06-28	Hoechst-Roussel Pharmaceuticals Inc.	{1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4420485A (en) *	1982-09-29	1983-12-13	Hoechst-Roussel Pharmaceuticals Inc.	1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]
FR2540107B1 (fr) *	1983-01-28	1986-10-17	Inst Rech Chim Biolog	Nouveaux derives d'halogenobenzophenone-oxime, utilisation en therapeutique et procede de preparation
FI92189C (fi) *	1986-03-17	1994-10-10	Eisai Co Ltd	Menetelmä lääkeaineina käyttökelpoisen difenyylimetaanijohdannaisen valmistamiseksi
US4898874A (en) *	1986-09-15	1990-02-06	A. H. Robins Company, Inc.	Acetic acid derivatives of 3-aryl-2,1-benzisoxazole and esters and amides thereof
JPH037961U (xx) *	1989-06-14	1991-01-25
US5114960A (en) *	1989-07-20	1992-05-19	Hoffmann-La Roche Inc.	Substituted isoxazole derivatives
PL1986633T3 (pl) *	2006-02-10	2015-01-30	Summit Oxford Ltd	Leczenie dystrofii mięśniowej Duchenne'a
JP5869677B2 (ja) *	2011-09-16	2016-02-24	ファイザー・インク	トランスサイレチン解離阻害剤の固体形態

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH1093669A4 (xx) *	1969-07-17	1971-02-15
FR2093173A5 (en) *	1970-06-04	1972-01-28	Gen Mills Inc	Substituted 2-hydroxybenzophenoximes for - copper extraction

1973
- 1973-10-23 GB GB49259/73A patent/GB1488003A/en not_active Expired
1974
- 1974-10-16 ZA ZA00746594A patent/ZA746594B/xx unknown
- 1974-10-16 US US05/515,131 patent/US3951999A/en not_active Expired - Lifetime
- 1974-10-18 IL IL45880A patent/IL45880A/xx unknown
- 1974-10-21 SE SE7413237A patent/SE424324B/xx unknown
- 1974-10-21 CH CH1404174A patent/CH595360A5/xx not_active IP Right Cessation
- 1974-10-21 CH CH566077A patent/CH605864A5/xx not_active IP Right Cessation
- 1974-10-22 DE DE19742450053 patent/DE2450053A1/de not_active Withdrawn
- 1974-10-22 IE IE2167/74A patent/IE40078B1/xx unknown
- 1974-10-22 CA CA212,030A patent/CA1042005A/en not_active Expired
- 1974-10-22 RO RO7480288A patent/RO74031A/ro unknown
- 1974-10-22 CS CS747227A patent/CS189671B2/cs unknown
- 1974-10-22 RO RO7499777A patent/RO78465A/ro unknown
- 1974-10-22 YU YU02824/74A patent/YU282474A/xx unknown
- 1974-10-22 SU SU742091795A patent/SU604491A3/ru active
- 1974-10-22 ES ES431247A patent/ES431247A1/es not_active Expired
- 1974-10-22 DK DK552674A patent/DK552674A/da not_active Application Discontinuation
- 1974-10-23 PH PH16443A patent/PH11022A/en unknown
- 1974-10-23 JP JP49122354A patent/JPS5912671B2/ja not_active Expired
- 1974-10-23 DD DD181858A patent/DD116830A5/xx unknown
- 1974-10-23 BE BE6044795A patent/BE821406A/xx not_active IP Right Cessation
- 1974-10-23 FR FR7435535A patent/FR2248041B1/fr not_active Expired
- 1974-10-23 NL NL7413848A patent/NL7413848A/xx not_active Application Discontinuation
- 1974-10-23 NZ NZ175780A patent/NZ175780A/xx unknown
- 1974-10-23 BG BG028023A patent/BG25991A3/xx unknown
- 1974-10-23 AT AT852374A patent/AT341520B/de not_active IP Right Cessation
- 1974-10-23 HU HU74LI00000266A patent/HU171613B/hu unknown
- 1974-10-23 AR AR256197A patent/AR209755A1/es active
- 1974-10-23 BG BG032026A patent/BG26531A4/xx unknown
1975
- 1975-12-29 AR AR261776A patent/AR221321A1/es active
- 1975-12-29 AR AR261777A patent/AR213086A1/es active
1976
- 1976-01-27 SU SU762315111A patent/SU608476A3/ru active
- 1976-01-28 SU SU762317502A patent/SU795459A3/ru active
- 1976-07-07 ES ES449655A patent/ES449655A1/es not_active Expired
- 1976-07-07 ES ES449654A patent/ES449654A1/es not_active Expired
1977
- 1977-03-18 FR FR7708208A patent/FR2361359A1/fr active Granted
- 1977-05-27 IL IL52179A patent/IL52179A0/xx unknown
- 1977-05-27 IL IL52180A patent/IL52180A0/xx unknown
- 1977-09-14 FR FR7727742A patent/FR2361328A1/fr active Granted
- 1977-09-14 AU AU28801/77A patent/AU510909B2/en not_active Expired
- 1977-09-21 SE SE7710599A patent/SE424325B/xx unknown
- 1977-09-21 SE SE7710600A patent/SE435713B/xx unknown
1981
- 1981-10-23 JP JP56169949A patent/JPS57154174A/ja active Granted

Also Published As

Publication number	Publication date
BE821406A (fr)	1975-04-23
FR2248041A1 (xx)	1975-05-16
HU171613B (hu)	1978-02-28
BG25991A3 (bg)	1979-01-12
IL52179A0 (en)	1977-07-31
SE424324B (sv)	1982-07-12
AU7454774A (en)	1976-04-29
DE2450053A1 (de)	1975-04-24
NZ175780A (en)	1978-04-03
YU282474A (en)	1982-02-28
CS189671B2 (en)	1979-04-30
ES449654A1 (es)	1977-07-01
JPS57154174A (en)	1982-09-22
US3951999A (en)	1976-04-20
SE7710599L (sv)	1977-09-21
FR2361359B1 (xx)	1979-07-20
AR221321A1 (es)	1981-01-30
DK552674A (xx)	1975-06-16
IL45880A0 (en)	1974-12-31
GB1488003A (en)	1977-10-05
ATA852374A (de)	1977-06-15
SE435713B (sv)	1984-10-15
AT341520B (de)	1978-02-10
SE7413237L (xx)	1975-04-24
AU510909B2 (en)	1980-07-17
JPS5077364A (xx)	1975-06-24
AR213086A1 (es)	1978-12-15
ES431247A1 (es)	1977-02-16
IE40078L (en)	1975-04-23
ZA746594B (en)	1976-06-30
AU2880177A (en)	1979-03-15
AR209755A1 (es)	1977-05-31
CA1042005A (en)	1978-11-07
SE7710600L (sv)	1977-09-21
IL52180A0 (en)	1977-07-31
IE40078B1 (en)	1979-03-14
SU604491A3 (ru)	1978-04-25
FR2361328A1 (fr)	1978-03-10
SU608476A3 (ru)	1978-05-25
FR2361328B1 (xx)	1979-07-13
SU795459A3 (ru)	1981-01-07
JPS5912671B2 (ja)	1984-03-24
PH11022A (en)	1977-10-25
RO74031A (ro)	1982-02-01
SE424325B (sv)	1982-07-12
JPS636066B2 (xx)	1988-02-08
NL7413848A (nl)	1975-04-25
CH605864A5 (xx)	1978-10-13
RO78465A (ro)	1982-02-26
ES449655A1 (es)	1977-07-01
BG26531A4 (bg)	1979-04-12
DD116830A5 (xx)	1975-12-12
FR2361359A1 (fr)	1978-03-10
CH595360A5 (xx)	1978-02-15
FR2248041B1 (xx)	1978-09-08

Publication	Publication Date	Title
IL43872A0 (en)	1974-03-14	Novel imidazotriazines,their preparation and pharmaceutical compositions containing them
IL44202A (en)	1978-10-31	(3-amino-2-hydroxy-propoxy)-diazines and -pyridine derivatives,their manufacture and pharmaceutical compositions containing them
IL46259A0 (en)	1975-03-13	New phenoxypropylamine derivatives,their preparation and pharmaceutical compositions containing them
IL46050A0 (en)	1975-02-10	Azepinoquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL45880A (en)	1979-09-30	3-phenyl-1,2-benzisoxyzole derivatives,their preparation and pharmaceutical compositions containing them
IL44762A0 (en)	1974-07-31	Indolyl derivatives,their preparation and pharmaceutical compositions containing them
IL47529A0 (en)	1975-08-31	New benzimidazolinone derivatives,their preparation and pharmaceutical compositions containing them
IL46250A0 (en)	1975-03-13	Novel oxazole derivatives,their preparation and pharmaceutical compositions containing them
IL44873A0 (en)	1974-07-31	New pyrazolo-s-triazine derivatives,their preparation and pharmaceutical compositions containing them
IL46183A (en)	1978-10-31	3-aminoalkylamino-1-phenoxy-2propanol derivatives,their preparation and pharmaceutical compositions comprising them
IL46264A0 (en)	1975-03-13	New pyrazole derivatives,their preparation and pharmaceutical compositions containing them
IL44427A0 (en)	1974-06-30	Dibenzothiepine derivatives,their manufacture and pharmaceutical compositions containing them
IL45609A0 (en)	1974-11-29	New isoquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL44222A0 (en)	1974-05-16	New diphenylpropylamines,their preparation and pharmaceutical compositions containing them
IL44095A0 (en)	1974-05-16	Novel diazepine derivatives,their preparation and pharmaceutical compositions containing them
IL44960A0 (en)	1974-09-10	Novel benzopyrane derivatives,their preparation and pharmaceutical compositions containing them
IL44627A0 (en)	1974-06-30	New pyrazol-5-one derivatives,their preparation and pharmaceutical compositions containing them
IL47196A0 (en)	1975-06-25	New 7-substituted-8-aminomethyl-isoflavone derivatives,their preparation and pharmaceutical compositions containing them
IL44895A0 (en)	1974-07-31	New thiazoloisoquinolines,their preparation and pharmaceutical compositions containing them
IL45995A0 (en)	1975-02-10	New substituted thiazole-2-carboxamides,their preparation and pharmaceutical compositions containing them
IL44267A0 (en)	1974-05-16	New glycopeptides,their preparation and pharmaceutical compositions containing them
IL45950A0 (en)	1974-12-31	2-aminothiazole derivatives,their preparation and pharmaceutical compositions containing them
IL44849A0 (en)	1974-07-31	New nitrocarbostyrils,their preparation and pharmaceutical compositions containing them
IL46116A0 (en)	1975-02-10	Novel alkenesulfonamides,their preparation and pharmaceutical compositions containing them
IL45970A0 (en)	1974-12-31	New thiazolylurea derivatives,their preparation and pharmaceutical compositions containing them