IL162562A0 - Substituted imidazolidines, method for the production thereof, use thereof as a drug or for diagnosis, and drug containing substituted imidazolid - Google Patents

Substituted imidazolidines, method for the production thereof, use thereof as a drug or for diagnosis, and drug containing substituted imidazolid

Info

Publication number: IL162562A0
Authority: IL; Israel
Prior art keywords: drug; substituted; imidazolid; diagnosis; production
Prior art date: 2001-12-21

Application number

IL16256202A

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-21

Filing date

2002-12-09

Publication date

2005-11-20

2002-12-09 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2005-11-20 Publication of IL162562A0 publication Critical patent/IL162562A0/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Tropical Medicine & Parasitology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Transplantation (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IL16256202A 2001-12-21 2002-12-09 Substituted imidazolidines, method for the production thereof, use thereof as a drug or for diagnosis, and drug containing substituted imidazolid IL162562A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10163239A DE10163239A1 (en)	2001-12-21	2001-12-21	Substituted imidazolidines, process for their preparation, their use as medicaments or diagnostic agents, and medicaments containing them
PCT/EP2002/013921 WO2003053434A1 (en)	2001-12-21	2002-12-09	Substituted imidazolidines, method for the production thereof, use thereof as a drug or for diagnosis, and drug containing substituted imidazolidines

Publications (1)

Publication Number	Publication Date
IL162562A0 true IL162562A0 (en)	2005-11-20

Family

ID=7710363

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL16256202A IL162562A0 (en)	2001-12-21	2002-12-09	Substituted imidazolidines, method for the production thereof, use thereof as a drug or for diagnosis, and drug containing substituted imidazolid
IL162562A IL162562A (en)	2001-12-21	2004-06-16	Substituted imidazolidines, method for the production thereof, use thereof as a drug or for diagnosis and drug containing substituted imidazolidines

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL162562A IL162562A (en)	2001-12-21	2004-06-16	Substituted imidazolidines, method for the production thereof, use thereof as a drug or for diagnosis and drug containing substituted imidazolidines

Country Status (27)

Country	Link
EP (1)	EP1461034B1 (en)
JP (1)	JP4571803B2 (en)
KR (1)	KR100959031B1 (en)
CN (1)	CN100339079C (en)
AR (1)	AR037932A1 (en)
AT (1)	ATE345797T1 (en)
AU (1)	AU2002361990B2 (en)
BR (1)	BR0215154A (en)
CA (1)	CA2470856A1 (en)
CO (1)	CO5590925A2 (en)
DE (2)	DE10163239A1 (en)
DK (1)	DK1461034T3 (en)
ES (1)	ES2275945T3 (en)
HR (1)	HRP20040573A2 (en)
HU (1)	HUP0600836A2 (en)
IL (2)	IL162562A0 (en)
MA (1)	MA27149A1 (en)
MX (1)	MXPA04005388A (en)
MY (1)	MY134344A (en)
NO (1)	NO20043009L (en)
PE (1)	PE20030741A1 (en)
PL (1)	PL368940A1 (en)
RS (1)	RS53204A (en)
RU (1)	RU2004122415A (en)
TW (1)	TW200305408A (en)
WO (1)	WO2003053434A1 (en)
ZA (1)	ZA200404149B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10323701A1 (en)	2003-05-22	2004-12-23	Aventis Pharma Deutschland Gmbh	Process for the synthesis of heterocyclic compounds
CA2531167C (en)	2003-06-30	2012-05-22	Sumitomo Chemical Company, Limited	Asymmetric urea compound and process for producing asymmetric compound by asymmetric conjugate addition reaction with the same as catalyst
DE10341240A1 (en) *	2003-09-08	2005-04-07	Aventis Pharma Deutschland Gmbh	Substituted thienoimidazoles, process for their preparation, their use as medicament or diagnostic agent, and medicament containing them
RU2703456C2 (en)	2014-07-25	2019-10-17	Тайсо Фармасьютикал Ко., Лтд.	Phenyltetrahydroisoquinoline compound, substituted with heteroaryl

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3202660A (en) *	1961-10-09	1965-08-24	Boehringer Sohn Ingelheim	Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
US3236857A (en) *	1961-10-09	1966-02-22	Boehringer Sohn Ingelheim	2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
EP0070084A3 (en) *	1981-04-24	1983-02-16	Beecham Group Plc	Imidazoline derivatives
DE3712385A1 (en) *	1987-04-11	1988-10-27	Boehringer Ingelheim Kg	2-(Phenylimino)imidazolidines
GB9313330D0 (en) *	1993-06-28	1993-08-11	Fujisawa Pharmaceutical Co	New compound and its preparation
EP0639573A1 (en) *	1993-08-03	1995-02-22	Hoechst Aktiengesellschaft	Benzocondensed five membered heterocycles, process of their preparation, their use as drug, as diagnostic means and pharmaceuticals containing it
DE4328869A1 (en) *	1993-08-27	1995-03-02	Hoechst Ag	Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them
KR100257129B1 (en) *	1993-09-11	2000-05-15	성재갑	Novel cephalosphorine antibiotics
US5552415A (en) *	1993-12-21	1996-09-03	Eli Lilly And Company	Method of inhibiting Alzheimer's Disease
DE19548812A1 (en) *	1995-12-27	1997-07-03	Hoechst Ag	Use of inhibitors of the cellular Na · + · / H · + · exchanger (NHE) for the manufacture of a medicament for respiratory stimulation
DE19633966A1 (en) *	1996-08-22	1998-02-26	Hoechst Ag	Phenyl-substituted alkenylcarboxylic acid guanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them
CA2282398A1 (en) *	1997-03-14	1998-09-17	Steven M. Ronkin	Inhibitors of impdh enzyme
DE19945302A1 (en) *	1999-09-22	2001-03-29	Merck Patent Gmbh	Biphenyl derivatives as NHE-3 inhibitors
DE19950898A1 (en) *	1999-10-22	2001-04-26	Aventis Pharma Gmbh	New heteroaryl substituted fluoroalkyl-benzoylguanidine derivatives useful for treatment of e.g. ischemias, cardiac infarction, angina, shock, atherosclerosis, cancer and metabolic disorders
DE19960204A1 (en) *	1999-12-14	2001-06-28	Aventis Pharma Gmbh	Substituted norlbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them
DE10015248A1 (en) *	2000-03-28	2001-10-04	Merck Patent Gmbh	Bisamidino compounds as NHE-3 inhibitors
DE10019062A1 (en) *	2000-04-18	2001-10-25	Merck Patent Gmbh	Use of known and new 2-guanidino-4-aryl-quinazoline derivatives as NHE-3 inhibitors useful for the treatment of e.g. hypertension, thrombosis, cardiac ischemia, peripheral and CNS ischemia
DE10060292A1 (en) *	2000-12-05	2002-06-20	Aventis Pharma Gmbh	Use of substituted benzimidazoles for the manufacture of a medicament for the treatment of diseases which can be influenced by inhibition of the Na + / H + exchanger and medicament containing them

2001
- 2001-12-21 DE DE10163239A patent/DE10163239A1/en not_active Withdrawn
2002
- 2002-12-09 PL PL02368940A patent/PL368940A1/en not_active Application Discontinuation
- 2002-12-09 DK DK02796586T patent/DK1461034T3/en active
- 2002-12-09 DE DE50208809T patent/DE50208809D1/en not_active Expired - Lifetime
- 2002-12-09 ES ES02796586T patent/ES2275945T3/en not_active Expired - Lifetime
- 2002-12-09 HU HU0600836A patent/HUP0600836A2/en unknown
- 2002-12-09 CA CA002470856A patent/CA2470856A1/en not_active Abandoned
- 2002-12-09 AU AU2002361990A patent/AU2002361990B2/en not_active Ceased
- 2002-12-09 RU RU2004122415/04A patent/RU2004122415A/en not_active Application Discontinuation
- 2002-12-09 IL IL16256202A patent/IL162562A0/en unknown
- 2002-12-09 AT AT02796586T patent/ATE345797T1/en not_active IP Right Cessation
- 2002-12-09 CN CNB028258177A patent/CN100339079C/en not_active Expired - Fee Related
- 2002-12-09 JP JP2003554191A patent/JP4571803B2/en not_active Expired - Fee Related
- 2002-12-09 RS YU53204A patent/RS53204A/en unknown
- 2002-12-09 MX MXPA04005388A patent/MXPA04005388A/en active IP Right Grant
- 2002-12-09 EP EP02796586A patent/EP1461034B1/en not_active Expired - Lifetime
- 2002-12-09 BR BR0215154-5A patent/BR0215154A/en not_active IP Right Cessation
- 2002-12-09 KR KR1020047009820A patent/KR100959031B1/en not_active IP Right Cessation
- 2002-12-09 WO PCT/EP2002/013921 patent/WO2003053434A1/en active IP Right Grant
- 2002-12-11 PE PE2002001194A patent/PE20030741A1/en not_active Application Discontinuation
- 2002-12-19 TW TW091136596A patent/TW200305408A/en unknown
- 2002-12-19 AR ARP020105018A patent/AR037932A1/en unknown
- 2002-12-20 MY MYPI20024821A patent/MY134344A/en unknown
2004
- 2004-05-27 ZA ZA200404149A patent/ZA200404149B/en unknown
- 2004-06-01 MA MA27709A patent/MA27149A1/en unknown
- 2004-06-16 IL IL162562A patent/IL162562A/en not_active IP Right Cessation
- 2004-06-17 CO CO04056920A patent/CO5590925A2/en not_active Application Discontinuation
- 2004-06-18 HR HR20040573A patent/HRP20040573A2/en not_active Application Discontinuation
- 2004-07-15 NO NO20043009A patent/NO20043009L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE10163239A1 (en)	2003-07-10
PL368940A1 (en)	2005-04-04
ATE345797T1 (en)	2006-12-15
TW200305408A (en)	2003-11-01
JP2005516947A (en)	2005-06-09
CN1606440A (en)	2005-04-13
MY134344A (en)	2007-12-31
RS53204A (en)	2006-10-27
RU2004122415A (en)	2005-03-27
AU2002361990A1 (en)	2003-07-09
AU2002361990B2 (en)	2008-10-09
MXPA04005388A (en)	2004-10-11
DK1461034T3 (en)	2007-03-26
HUP0600836A2 (en)	2008-04-28
ES2275945T3 (en)	2007-06-16
CN100339079C (en)	2007-09-26
JP4571803B2 (en)	2010-10-27
KR20040068322A (en)	2004-07-30
AR037932A1 (en)	2004-12-22
CO5590925A2 (en)	2005-12-30
BR0215154A (en)	2004-10-19
ZA200404149B (en)	2006-05-31
DE50208809D1 (en)	2007-01-04
NO20043009L (en)	2004-07-15
EP1461034A1 (en)	2004-09-29
CA2470856A1 (en)	2003-07-03
IL162562A (en)	2009-12-24
WO2003053434A1 (en)	2003-07-03
KR100959031B1 (en)	2010-05-20
HRP20040573A2 (en)	2004-10-31
PE20030741A1 (en)	2003-09-29
EP1461034B1 (en)	2006-11-22
MA27149A1 (en)	2005-01-03

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