IL150374A0 - Compounds and methods for modulating cerebral amyloid angiopathy - Google Patents
Compounds and methods for modulating cerebral amyloid angiopathyInfo
- Publication number
- IL150374A0 IL150374A0 IL15037400A IL15037400A IL150374A0 IL 150374 A0 IL150374 A0 IL 150374A0 IL 15037400 A IL15037400 A IL 15037400A IL 15037400 A IL15037400 A IL 15037400A IL 150374 A0 IL150374 A0 IL 150374A0
- Authority
- IL
- Israel
- Prior art keywords
- compounds
- methods
- amyloid angiopathy
- cerebral amyloid
- modulating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17187799P | 1999-12-23 | 1999-12-23 | |
PCT/IB2000/002078 WO2001085093A2 (en) | 1999-12-23 | 2000-12-22 | Compounds and methods for modulating cerebral amyloid angiopathy |
Publications (1)
Publication Number | Publication Date |
---|---|
IL150374A0 true IL150374A0 (en) | 2002-12-01 |
Family
ID=22625484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15037400A IL150374A0 (en) | 1999-12-23 | 2000-12-22 | Compounds and methods for modulating cerebral amyloid angiopathy |
Country Status (11)
Country | Link |
---|---|
US (2) | US6670399B2 (zh) |
EP (1) | EP1251837A2 (zh) |
JP (1) | JP2003532656A (zh) |
KR (3) | KR20090016517A (zh) |
CN (1) | CN1434706A (zh) |
AU (1) | AU8431301A (zh) |
BR (1) | BR0016652A (zh) |
CA (1) | CA2395314A1 (zh) |
IL (1) | IL150374A0 (zh) |
MX (1) | MXPA02006196A (zh) |
WO (1) | WO2001085093A2 (zh) |
Families Citing this family (68)
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US20040208875A1 (en) * | 1995-03-15 | 2004-10-21 | Queen's University At Kingston | Method for treating amyloidosis |
WO1997021728A1 (en) | 1995-12-12 | 1997-06-19 | Karolinska Innovations Ab | PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b) |
US20020022657A1 (en) * | 1998-02-11 | 2002-02-21 | Francine Gervais | Methods for modulating neuronal cell death |
US6310073B1 (en) * | 1998-07-28 | 2001-10-30 | Queen's University At Kingston | Methods and compositions to treat glycosaminoglycan-associated molecular interactions |
US7060670B1 (en) * | 1999-05-05 | 2006-06-13 | Neurochem (International) Limited | Stereoselective antifibrillogenic peptides and peptidomimetics thereof |
AU5994900A (en) * | 1999-07-09 | 2001-01-30 | Isis Innovation Limited | Compounds for inhibiting diseases and preparing cells for transplantation |
US20020094335A1 (en) * | 1999-11-29 | 2002-07-18 | Robert Chalifour | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
US20070135337A2 (en) * | 1999-11-29 | 2007-06-14 | Neurochem (International) Limited | Vaccine for the Prevention and Treatment of Alzheimer's and Amyloid Related Diseases |
WO2001085093A2 (en) * | 1999-12-23 | 2001-11-15 | Neurochem, Inc. | Compounds and methods for modulating cerebral amyloid angiopathy |
US7311893B2 (en) * | 2000-07-25 | 2007-12-25 | Neurochem (International) Limited | Amyloid targeting imaging agents and uses thereof |
US20050107345A1 (en) * | 2002-03-01 | 2005-05-19 | Doherty George A. | Aminoalkylphosphonates and related compounds as edg receptor agonists |
BR0317747A (pt) * | 2002-12-24 | 2005-11-22 | Neurochem Int Ltd | Método de tratamento terapêutico concomitante de um indivìduo, composição farmacêutica, kit, uso de um primeiro agente e um segundo agente, e, métodos de prevenir ou tratar uma doença relacionada com amilóide-b, doença de alzheimer e insuficiência cognitiva suave |
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
EP1477493A1 (en) * | 2003-05-15 | 2004-11-17 | Bayer HealthCare AG | Isotope coded affinity tags |
AU2011250847B2 (en) * | 2003-06-23 | 2013-06-20 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
CA2529269C (en) * | 2003-06-23 | 2012-02-07 | Neurochem (International) Limited | Improved pharmaceutical drug candidates and methods for preparation thereof |
US20050142191A1 (en) * | 2003-06-23 | 2005-06-30 | Neurochem (International) Limited | Pharmaceutical formulations of amyloid inhibiting compounds |
JP5146714B2 (ja) * | 2003-06-23 | 2013-02-20 | ビーエイチアイ リミテッド パートナーシップ | アミロイド関連疾患を治療するための方法および組成物 |
US7244764B2 (en) | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
US7414076B2 (en) * | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
US20060079578A1 (en) * | 2003-06-23 | 2006-04-13 | Julie Laurin | Pharmaceutical formulations of amyloid inhibiting compounds |
US7262223B2 (en) | 2004-01-23 | 2007-08-28 | Neurochem (International) Limited | Amidine derivatives for treating amyloidosis |
WO2007049098A2 (en) * | 2004-06-18 | 2007-05-03 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
EP1765781A2 (en) | 2004-07-09 | 2007-03-28 | Sigma-Aldrich Co. | Optically enhanced chiral ionic liquids |
CA2574460A1 (en) | 2004-07-23 | 2006-02-02 | Sigma-Aldrich Co. | High stability diionic liquid salts |
US8168830B2 (en) | 2004-07-23 | 2012-05-01 | Sigma-Aldrich Co. Llc | High stability diionic liquid salts |
US20090215717A1 (en) * | 2004-08-05 | 2009-08-27 | Ivax Drug Research Institute Ltd. | Sulfated oligosaccharides |
WO2006059245A2 (en) * | 2004-11-16 | 2006-06-08 | Neurochem (International) Limited | Compounds for the treatment of cns and amyloid associated diseases |
US20080025962A1 (en) * | 2004-11-30 | 2008-01-31 | Angesmg,Inc. | Remedy for Alzheimer's Disease |
AU2005326962A1 (en) | 2004-12-22 | 2006-08-17 | Bellus Health (International) Limited | Methods and compositions for treating amyloid-related diseases |
JP2008535907A (ja) * | 2005-04-12 | 2008-09-04 | ニユーロケム(インターナショナル)、リミテッド | アミロイド阻害化合物の薬学的製剤 |
TW200716088A (en) * | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
WO2007023389A2 (en) * | 2005-07-21 | 2007-03-01 | Neurochem (International) Limited | Polymorphic forms of 3-amino-1-propanesulfonic acid |
KR20080090408A (ko) | 2005-11-30 | 2008-10-08 | 아보트 러보러터리즈 | 항-Aβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법 |
CA2631195C (en) | 2005-11-30 | 2016-04-05 | Abbott Laboratories | Monoclonal antibodies against amyloid beta protein and uses thereof |
EP1968561B8 (en) * | 2005-12-22 | 2010-10-20 | Kiacta Sàrl | Treatment of diabetic nephropathy |
EP3851447B1 (en) | 2006-10-12 | 2023-09-06 | Bellus Health Inc. | Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid |
WO2008070284A2 (en) * | 2006-10-16 | 2008-06-12 | Johnnie B. Byrd, Sr. Alzheimer's Center And Research Institute | Amyloid beta peptides and methods of uses thereof |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
JP2010513219A (ja) * | 2006-12-22 | 2010-04-30 | ベラス ヘルス (インターナショナル) リミテッド | 腎臓の疾患、糖尿病性腎症及び脂質代謝異常の治療 |
WO2008095069A2 (en) * | 2007-01-31 | 2008-08-07 | Sigma-Aldrich Co. | High stability polyionic liquid salts |
WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
US7618944B2 (en) * | 2007-03-01 | 2009-11-17 | Intezyne Technologies, Inc. | Encapsulated amyloid-beta peptides |
GB0708507D0 (en) * | 2007-05-02 | 2007-06-13 | Queen Mary & Westfield College | Substituted phosphonates and their use |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
EP2183258A2 (en) * | 2007-08-01 | 2010-05-12 | Centre National de la Recherche Scientifique (CNRS) | Thiophosphi(o)nic acid derivatives and their use as agonists or antagonists for metabotropic glutamate receptors |
US20090076167A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched tramiprosate |
SG10201505369QA (en) | 2007-10-05 | 2015-08-28 | Genentech Inc | Use of anti-amyloid beta antibody in ocular diseases |
US8231895B2 (en) | 2008-05-22 | 2012-07-31 | Universidade De Coimbra | Targeted delivery to human diseases and disorders |
EP2180003A1 (en) * | 2008-10-21 | 2010-04-28 | Zentiva, k.s. | Preparation of ibandronate trisodium |
US9023767B2 (en) * | 2009-05-07 | 2015-05-05 | Memorial Sloan-Kettering Cancer Center | γ-Secretase substrates and methods of use |
EP2464626A4 (en) | 2009-08-10 | 2015-12-16 | Bhi Ltd Partnership | PROCESSES, COMPOUNDS AND COMPOSITIONS FOR THE EXPORTS OF 1,3-PROPANE-SULFONIC ACID |
EP2289900A1 (en) * | 2009-08-26 | 2011-03-02 | Humboldt Universität zu Berlin | Bisphosphonates as inhibitors of acid sphingomyelinase |
MX360403B (es) | 2010-04-15 | 2018-10-31 | Abbvie Inc | Proteinas de union a amiloide beta. |
CN103179981B (zh) | 2010-07-30 | 2017-02-08 | Ac免疫有限公司 | 安全和功能性的人源化抗β‑淀粉样蛋白抗体 |
EP2603524A1 (en) | 2010-08-14 | 2013-06-19 | AbbVie Inc. | Amyloid-beta binding proteins |
WO2012033831A2 (en) | 2010-09-07 | 2012-03-15 | Memorial Sloan-Kettering Cancer Center | Methods and compositions for gamma-secretase assay |
US12085575B2 (en) | 2011-12-01 | 2024-09-10 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for detecting proteinopathies |
US10962553B2 (en) | 2011-12-01 | 2021-03-30 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for detecting proteinopathies |
US9599626B2 (en) * | 2011-12-01 | 2017-03-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Therapeutic and diagnostic method for ataxia-telangiectasia |
WO2013158846A1 (en) * | 2012-04-20 | 2013-10-24 | Baylor College Of Medicine | Novel dxr inhibitors for antimicrobial therapy |
CN102793694B (zh) * | 2012-08-14 | 2014-06-04 | 武汉华纳联合药业有限公司 | 3-氨基-1-丙烷磺酸及其衍生物在制备治疗脑卒中的药物中的应用 |
JP5804463B2 (ja) * | 2012-12-27 | 2015-11-04 | 国立研究開発法人科学技術振興機構 | 環状ペプチド及びこれを含有する医薬 |
CN108623501B (zh) | 2017-03-21 | 2022-04-19 | 润佳(苏州)医药科技有限公司 | 同位素富集的3-氨基-1-丙磺酸衍生物及其用途 |
CN110520432B (zh) * | 2017-04-17 | 2022-08-02 | 株式会社Nahls | 光学活性的2-氨基-膦酰基烷酸、光学活性的2-氨基-膦酰基烷酸盐及它们的水合物 |
RU2696684C1 (ru) * | 2018-09-18 | 2019-08-05 | Федеральное государственное бюджетное научное учреждение "Научный центр неврологии" (ФГБНУ НЦН) | Способ определения типов когнитивных расстройств у больных церебральной микроангиопатией |
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CA1140049A (en) | 1977-12-22 | 1983-01-25 | Dke J.E. Helgstran | Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid |
US4540564A (en) | 1982-05-18 | 1985-09-10 | University Of Florida | Brain-specific drug delivery |
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US5166320A (en) | 1987-04-22 | 1992-11-24 | University Of Connecticut | Carrier system and method for the introduction of genes into mammalian cells |
US4883666A (en) | 1987-04-29 | 1989-11-28 | Massachusetts Institute Of Technology | Controlled drug delivery system for treatment of neural disorders |
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US5643562A (en) | 1993-03-29 | 1997-07-01 | Queen's University Of Kingston | Method for treating amyloidosis |
US5840294A (en) * | 1993-03-29 | 1998-11-24 | Queen's University At Kingston | Method for treating amyloidosis |
DE69434571T2 (de) * | 1993-03-29 | 2006-08-03 | Queen's University At Kingston, Kingston | Propan-1,3-disulphonsäure und deren pharmazeutisch akzeptable Salze zur Behandlung von Amyloidosis |
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US6168776B1 (en) * | 1994-07-19 | 2001-01-02 | University Of Pittsburgh | Alkyl, alkenyl and alkynyl Chrysamine G derivatives for the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition |
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DE4434654C2 (de) | 1994-09-28 | 1996-10-10 | Arburg Gmbh & Co | Verfahren zur Beeinflussung zyklisch ablaufender Prozesse |
US5817626A (en) * | 1995-03-14 | 1998-10-06 | Praecis Pharmaceuticals Incorporated | Modulators of beta-amyloid peptide aggregation |
US5948763A (en) | 1995-06-07 | 1999-09-07 | New York University | Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits |
US5931809A (en) | 1995-07-14 | 1999-08-03 | Depotech Corporation | Epidural administration of therapeutic compounds with sustained rate of release |
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CA2267065A1 (en) | 1996-11-22 | 1998-05-28 | Elan Pharmaceuticals, Inc. | N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositionscomprising same, and methods for inhibiting beta-amyloid peptide release a nd/or its synthesis by use of such compounds |
PE27799A1 (es) * | 1996-12-10 | 1999-03-18 | Novartis Ag | Formulaciones y formas polimorficas de desferrioxamina y su preparacion |
AU5727798A (en) * | 1996-12-23 | 1998-07-17 | Texas A & M University, The | Anti-amyloidogenic agents |
WO1999008685A1 (en) * | 1997-08-18 | 1999-02-25 | Queen's University At Kingston | Phosphono-carboxylate compounds for treating amyloidosis |
US5869469A (en) | 1997-08-18 | 1999-02-09 | Queen's University At Kingston | Phosphonocarboxylate compounds for treating amyloidosis |
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WO2001085093A2 (en) * | 1999-12-23 | 2001-11-15 | Neurochem, Inc. | Compounds and methods for modulating cerebral amyloid angiopathy |
-
2000
- 2000-12-22 WO PCT/IB2000/002078 patent/WO2001085093A2/en not_active Application Discontinuation
- 2000-12-22 CA CA002395314A patent/CA2395314A1/en not_active Abandoned
- 2000-12-22 IL IL15037400A patent/IL150374A0/xx unknown
- 2000-12-22 CN CN00819104A patent/CN1434706A/zh active Pending
- 2000-12-22 BR BR0016652-9A patent/BR0016652A/pt not_active Application Discontinuation
- 2000-12-22 JP JP2001581748A patent/JP2003532656A/ja active Pending
- 2000-12-22 AU AU84313/01A patent/AU8431301A/en not_active Abandoned
- 2000-12-22 KR KR1020097001295A patent/KR20090016517A/ko active Search and Examination
- 2000-12-22 US US09/747,408 patent/US6670399B2/en not_active Expired - Fee Related
- 2000-12-22 MX MXPA02006196A patent/MXPA02006196A/es not_active Application Discontinuation
- 2000-12-22 EP EP00993855A patent/EP1251837A2/en not_active Withdrawn
- 2000-12-22 KR KR1020027008226A patent/KR20020063266A/ko not_active Application Discontinuation
- 2000-12-22 KR KR1020077030145A patent/KR20080003945A/ko not_active Application Discontinuation
-
2003
- 2003-11-10 US US10/705,028 patent/US20080317834A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MXPA02006196A (es) | 2002-12-09 |
US6670399B2 (en) | 2003-12-30 |
US20080317834A1 (en) | 2008-12-25 |
WO2001085093A2 (en) | 2001-11-15 |
WO2001085093A9 (en) | 2002-09-26 |
KR20090016517A (ko) | 2009-02-13 |
US20030003141A1 (en) | 2003-01-02 |
EP1251837A2 (en) | 2002-10-30 |
CN1434706A (zh) | 2003-08-06 |
AU8431301A (en) | 2001-11-20 |
WO2001085093A3 (en) | 2002-08-29 |
JP2003532656A (ja) | 2003-11-05 |
CA2395314A1 (en) | 2001-11-15 |
KR20020063266A (ko) | 2002-08-01 |
KR20080003945A (ko) | 2008-01-08 |
BR0016652A (pt) | 2002-11-19 |
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