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IL100119A0 - Optically-active thiazoloisoindolinone derivatives with antiviral action - Google Patents

Optically-active thiazoloisoindolinone derivatives with antiviral action

Info

Publication number
IL100119A0
IL100119A0 IL100119A IL10011991A IL100119A0 IL 100119 A0 IL100119 A0 IL 100119A0 IL 100119 A IL100119 A IL 100119A IL 10011991 A IL10011991 A IL 10011991A IL 100119 A0 IL100119 A0 IL 100119A0
Authority
IL
Israel
Prior art keywords
optically
thiazoloisoindolinone
derivatives
active
antiviral action
Prior art date
Application number
IL100119A
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4037674A external-priority patent/DE4037674A1/en
Priority claimed from DE19914122418 external-priority patent/DE4122418A1/en
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of IL100119A0 publication Critical patent/IL100119A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

The present invention relates to optically active thiazoloisoindolinones of general formulae (I) and (II) where: R is a hydrogen atom or a straight-chained or branched, saturated or unsaturated aliphatic radical with 1-7 carbon atoms which may also be substituted by phenyl, or a phenyl ring which may be singly or multiply substituted by C1-C4-alkyl, C1-C4-alkoxy, hydroxy, trifluoromethyl, C1-C4-alkyl sulphonyl or a halogen; n is 0, 1 or 2; and their pharmacologically acceptable salts and tautomers. The object of the invention also includes medicaments containing the compounds of formula (I) or (II) and their use for the production of medicaments to treat viral or retroviral infections.
IL100119A 1990-11-27 1991-11-21 Optically-active thiazoloisoindolinone derivatives with antiviral action IL100119A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4037674A DE4037674A1 (en) 1990-11-27 1990-11-27 New 2,3-di:hydro:thiazolo:isoindolone derivs.
DE19914122418 DE4122418A1 (en) 1991-07-06 1991-07-06 Optically active thiazolo:isoindolinone derivs. - are antiviral agents, effective against diseases caused by DNA and by RNA viruses, and by retrovirus(es), esp. HIV

Publications (1)

Publication Number Publication Date
IL100119A0 true IL100119A0 (en) 1992-08-18

Family

ID=25898790

Family Applications (1)

Application Number Title Priority Date Filing Date
IL100119A IL100119A0 (en) 1990-11-27 1991-11-21 Optically-active thiazoloisoindolinone derivatives with antiviral action

Country Status (12)

Country Link
EP (1) EP0559815B1 (en)
JP (1) JPH06502634A (en)
CN (1) CN1062732A (en)
AT (1) ATE127467T1 (en)
AU (1) AU8910491A (en)
CA (1) CA2095255A1 (en)
DE (1) DE59106440D1 (en)
ES (1) ES2079850T3 (en)
IE (1) IE914100A1 (en)
IL (1) IL100119A0 (en)
PT (1) PT99609A (en)
WO (1) WO1992009606A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4129779A1 (en) * 1991-09-07 1993-03-11 Boehringer Mannheim Gmbh NEW TRICYCLIC THIAZOLE AND OXAZOLE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THEM
WO2002066479A1 (en) * 2001-02-23 2002-08-29 Banyu Pharmaceutical Co.,Ltd. Novel isoindole derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH433321A (en) * 1964-02-11 1967-04-15 Geigy Ag J R Process for the preparation of new, condensed heterocyclic compounds
CH469733A (en) * 1965-07-27 1969-03-15 Geigy Ag J R Process for the preparation of new, condensed heterocyclic compounds

Also Published As

Publication number Publication date
CN1062732A (en) 1992-07-15
ATE127467T1 (en) 1995-09-15
CA2095255A1 (en) 1992-05-28
WO1992009606A1 (en) 1992-06-11
EP0559815B1 (en) 1995-09-06
EP0559815A1 (en) 1993-09-15
DE59106440D1 (en) 1995-10-12
IE914100A1 (en) 1992-06-03
JPH06502634A (en) 1994-03-24
PT99609A (en) 1992-10-30
ES2079850T3 (en) 1996-01-16
AU8910491A (en) 1992-06-25

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