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IE45336L - Antimicrobial bis-pyridinium compounds - Google Patents

Antimicrobial bis-pyridinium compounds

Info

Publication number
IE45336L
IE45336L IE770386A IE38677A IE45336L IE 45336 L IE45336 L IE 45336L IE 770386 A IE770386 A IE 770386A IE 38677 A IE38677 A IE 38677A IE 45336 L IE45336 L IE 45336L
Authority
IE
Ireland
Prior art keywords
image
compounds
pyridinium compounds
anion
prepared
Prior art date
Application number
IE770386A
Other versions
IE45336B1 (en
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/734,729 external-priority patent/US4107313A/en
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of IE45336L publication Critical patent/IE45336L/en
Publication of IE45336B1 publication Critical patent/IE45336B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The compounds of formulae I and II in which the symbols have the meaning given in Claim 1 are prepared by reaction of 2 mole parts of a compound <IMAGE> or, respectively, <IMAGE>, with one mole part of a compound Z-Y-Z or, respectively, <IMAGE>, Z being an atom or radical which splits in the form of an anion which is then the anion A. The latter can be exchanged by metathesis against other anions A. The compounds thus prepared have antibacterial, fungicidal and viricidal properties and can be used, for example, in medicine, as disinfectants and as antimicrobial agents. <IMAGE> [GB1533952A]
IE386/77A 1976-02-25 1977-02-23 Usantimicrobial bis pyridinium compounds IE45336B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66112876A 1976-02-25 1976-02-25
US66110176A 1976-02-25 1976-02-25
US72131576A 1976-09-07 1976-09-07
US05/734,729 US4107313A (en) 1976-02-25 1976-10-22 α,α-Bis-[4-(R-amino)-1-pyridinium]xylenes and antibacterial and antifungal uses

Publications (2)

Publication Number Publication Date
IE45336L true IE45336L (en) 1977-08-25
IE45336B1 IE45336B1 (en) 1982-08-11

Family

ID=27505307

Family Applications (1)

Application Number Title Priority Date Filing Date
IE386/77A IE45336B1 (en) 1976-02-25 1977-02-23 Usantimicrobial bis pyridinium compounds

Country Status (23)

Country Link
JP (1) JPS6033108B2 (en)
AR (2) AR214876A1 (en)
AT (1) AT355571B (en)
AU (1) AU510149B2 (en)
BE (1) BE851807A (en)
CA (1) CA1073911A (en)
CH (1) CH620907A5 (en)
DE (1) DE2708331A1 (en)
DK (1) DK147638C (en)
ES (1) ES456252A1 (en)
FI (1) FI66850C (en)
FR (1) FR2342286A1 (en)
GB (1) GB1533952A (en)
HK (1) HK67484A (en)
IE (1) IE45336B1 (en)
IL (1) IL51520A (en)
LU (1) LU76837A1 (en)
MX (1) MX5132E (en)
NL (1) NL186086C (en)
NO (2) NO148779C (en)
PH (2) PH22315A (en)
PT (1) PT66224B (en)
SE (1) SE432421B (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE32300E (en) * 1979-08-13 1986-12-02 Sterling Drug Inc. Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use thereof
US4420484A (en) 1979-08-13 1983-12-13 Sterling Drug Inc. Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use therof
DE19647413A1 (en) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituted nitrogen heterocycles, processes for their preparation and their use as pesticides
DE19647317A1 (en) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituted nitrogen heterocycles, processes for their preparation and their use as pesticides
DE19647402A1 (en) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituted nitrogen heterocycles, processes for their preparation and their use as pesticides
DE10005853C1 (en) 2000-02-10 2002-02-07 Schuelke & Mayr Gmbh Process for the preparation of bis- (4-amino-1-pyridinium) alkanes
DE10205883A1 (en) * 2002-02-13 2003-08-21 Schuelke & Mayr Gmbh Aqueous antiseptic based on bispyridiniumalkanes
TWI278315B (en) * 2003-06-13 2007-04-11 Ind Tech Res Inst A compound having anti-virus activity
ES2237332B1 (en) * 2004-01-14 2006-11-01 Consejo Sup. Investig. Cientificas DERIVATIVES OF PIRIDINIO AND QUINOLINIO.
DE102005002644A1 (en) * 2005-01-19 2006-07-20 Schülke & Mayr GmbH Compositions for hygienic hand disinfection and disinfecting hand washing
DE102005002645A1 (en) 2005-01-19 2006-07-20 Schülke & Mayr GmbH Alcoholic compositions for disinfection
DE102005002643B4 (en) * 2005-01-19 2007-11-22 Schülke & Mayr GmbH Compositions for hygienic hand disinfection and disinfecting hand washing
DE102005045145A1 (en) * 2005-09-15 2007-03-29 Schülke & Mayr GmbH Use of octenidine dihydrochloride in semisolid preparations
DE102005063375A1 (en) 2005-09-15 2007-04-19 Schülke & Mayr GmbH Antimicrobial preparations containing octenidine dihydrochloride encapsulated in liposomes
DE102005048132A1 (en) * 2005-10-06 2007-04-12 Bayer Innovation Gmbh Process for producing antimicrobial plastic compositions
DE102005048131A1 (en) * 2005-10-06 2007-04-12 Bayer Innovation Gmbh Antimicrobial plastic composition with low elution rate and long efficacy
DE102006012991A1 (en) 2006-03-22 2007-10-11 Bayer Innovation Gmbh Method and device for optically reading information
DE102006051891A1 (en) * 2006-10-31 2008-05-08 Schülke & Mayr GmbH Antimicrobial composition containing Bispyridiniumalkan
DE102008011691A1 (en) 2008-02-28 2009-09-10 Schülke & Mayr GmbH Stabilized antimicrobial composition containing bispyridiniumalkane
DE102009049504A1 (en) 2009-10-15 2011-04-21 Schülke & Mayr GmbH Wound and mucous membrane antiseptic based on bispyridiniumalkanes
DE202010007433U1 (en) 2010-04-20 2011-06-01 Klosterfrau Berlin GmbH, 12277 Gel, especially lubricating gel
EP2384733B1 (en) * 2010-05-07 2016-07-27 Ivoclar Vivadent AG Antimicrobial dental materials
DE102010025932A1 (en) 2010-07-02 2012-01-05 Schülke & Mayr GmbH Antiseptic based on bispyridiniumalkanes
DE102011077432A1 (en) * 2011-06-10 2012-12-13 Schülke & Mayr GmbH Use of bispyridiniumalkanes to kill spores
DE102012215511A1 (en) 2012-08-31 2014-06-12 Schülke & Mayr GmbH Process for the preparation of a semi-solid preparation containing bispyridiniumalkane
DE102013223657A1 (en) 2013-11-20 2015-05-21 Schülke & Mayr GmbH Kit for the production of Bispyridiniumalkan containing foams
DE102014107412A1 (en) 2014-05-26 2015-12-17 Schülke & Mayr GmbH Colored disinfecting preparation based on bispyridiniumalkane
DE102014107413A1 (en) 2014-05-26 2015-11-26 Schülke & Mayr GmbH Kit for coloring of disinfected areas of a surface
DE102014115080A1 (en) 2014-10-16 2016-04-21 Schülke & Mayr GmbH Use of fatty acid esters to improve the antimicrobial effectiveness of an alcoholic disinfectant
US11014907B2 (en) * 2017-08-21 2021-05-25 Dishman Carbogen Amcis Ltd. Octendidine based compounds
EP3771337A1 (en) 2019-07-29 2021-02-03 The Procter & Gamble Company Antimicrobial composition
EP3771770A1 (en) 2019-07-29 2021-02-03 The Procter & Gamble Company Antimicrobial freshening compositions
EP3771339A1 (en) * 2019-07-29 2021-02-03 The Procter & Gamble Company Disinfectant composition
EP3771338A1 (en) 2019-07-29 2021-02-03 The Procter & Gamble Company Acidic antimicrobial composition
EP3771741A1 (en) 2019-07-29 2021-02-03 The Procter & Gamble Company Fabric treatment
EP3816272B1 (en) 2019-10-31 2023-11-01 The Procter & Gamble Company Fabric care composition
CN114989076A (en) * 2022-06-07 2022-09-02 八叶草健康产业研究院(厦门)有限公司 Preparation method of octenidine base

Also Published As

Publication number Publication date
MX5132E (en) 1983-03-28
AR214876A1 (en) 1979-08-15
AR218052A1 (en) 1980-05-15
IL51520A0 (en) 1977-04-29
DE2708331C2 (en) 1991-03-21
PH25097A (en) 1991-02-19
NO150758B (en) 1984-09-03
FR2342286B1 (en) 1979-03-09
NO770631L (en) 1977-08-26
IL51520A (en) 1980-12-31
CH620907A5 (en) 1980-12-31
BE851807A (en) 1977-08-25
NL186086B (en) 1990-04-17
SE432421B (en) 1984-04-02
JPS52105228A (en) 1977-09-03
DK147638B (en) 1984-10-29
DK147638C (en) 1985-07-15
NO148779B (en) 1983-09-05
FR2342286A1 (en) 1977-09-23
NO148779C (en) 1983-12-14
PT66224B (en) 1978-07-14
JPS6033108B2 (en) 1985-08-01
PH22315A (en) 1988-07-29
FI770593A (en) 1977-08-26
DE2708331A1 (en) 1977-09-08
ES456252A1 (en) 1978-02-01
NL186086C (en) 1990-09-17
AU510149B2 (en) 1980-06-12
GB1533952A (en) 1978-11-29
IE45336B1 (en) 1982-08-11
FI66850C (en) 1984-12-10
FI66850B (en) 1984-08-31
NO823274L (en) 1977-08-26
NO150758C (en) 1984-12-12
HK67484A (en) 1984-09-07
LU76837A1 (en) 1977-09-12
DK81277A (en) 1977-08-26
SE7702072L (en) 1977-10-10
AU2258277A (en) 1978-08-31
NL7701965A (en) 1977-08-29
AT355571B (en) 1980-03-10
CA1073911A (en) 1980-03-18
PT66224A (en) 1977-03-01
ATA129777A (en) 1979-08-15

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