IE43802L - N-aryl-n-(4-piperidinyl) arylacetamide derivatives. - Google Patents
N-aryl-n-(4-piperidinyl) arylacetamide derivatives.Info
- Publication number
- IE43802L IE43802L IE762095A IE209576A IE43802L IE 43802 L IE43802 L IE 43802L IE 762095 A IE762095 A IE 762095A IE 209576 A IE209576 A IE 209576A IE 43802 L IE43802 L IE 43802L
- Authority
- IE
- Ireland
- Prior art keywords
- piperidinyl
- aryl
- derivatives
- formula
- arylacetamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
N-Aryl-N-(4-piperidinyl)arylacetamides of the formula <IMAGE> and their salts with acids, the substituents in the formula being defined in Claim 1, are prepared. These compounds are obtained by acylating corresponding piperidine derivatives with an arylacetyl halide. The resulting compounds can be used for the drug therapy of cardiac arrhythmias.
[GB1539473A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61513175A | 1975-09-23 | 1975-09-23 | |
| US71375676A | 1976-08-12 | 1976-08-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE43802L true IE43802L (en) | 1977-03-23 |
| IE43802B1 IE43802B1 (en) | 1981-06-03 |
Family
ID=27087421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2095/76A IE43802B1 (en) | 1975-09-23 | 1976-09-22 | Novel-n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
Country Status (29)
| Country | Link |
|---|---|
| JP (1) | JPS6016417B2 (en) |
| AT (1) | AT363935B (en) |
| AU (1) | AU510029B2 (en) |
| BG (1) | BG27543A3 (en) |
| CA (1) | CA1068271A (en) |
| CH (1) | CH628623A5 (en) |
| CS (1) | CS222663B2 (en) |
| DE (1) | DE2642856A1 (en) |
| DK (1) | DK150478C (en) |
| ES (1) | ES451768A1 (en) |
| FI (1) | FI61482C (en) |
| FR (1) | FR2325377A1 (en) |
| GB (1) | GB1539473A (en) |
| GR (1) | GR58469B (en) |
| HU (1) | HU172964B (en) |
| IE (1) | IE43802B1 (en) |
| IL (1) | IL50522A (en) |
| IT (1) | IT1073893B (en) |
| LU (1) | LU75837A1 (en) |
| NL (1) | NL187267C (en) |
| NO (1) | NO147672C (en) |
| NZ (1) | NZ181972A (en) |
| PH (1) | PH12497A (en) |
| PL (2) | PL192578A1 (en) |
| PT (1) | PT65631B (en) |
| RO (1) | RO70079A (en) |
| SE (1) | SE427839B (en) |
| SU (1) | SU747424A3 (en) |
| YU (1) | YU39973B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA765684B (en) * | 1975-09-23 | 1978-04-26 | Janssen Pharmaceutica Nv | Novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
| JPS62260786A (en) * | 1986-05-08 | 1987-11-13 | 株式会社ヘキトク | Line system for manufacturing smoked roof tile |
| JO2769B1 (en) | 2005-10-26 | 2014-03-15 | جانسين فارماسوتيكا ان. في | Fast Dissociting Dopamine 2 Receptor Antagonists |
| JO2642B1 (en) | 2006-12-08 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Fast Dissociating Dopamine 2 Receptor Antagonists |
| JO2849B1 (en) | 2007-02-13 | 2015-03-15 | جانسين فارماسوتيكا ان. في | Fast -Dissociating Dopamine 2 Receptor Antagonists |
| KR20100016498A (en) * | 2007-04-23 | 2010-02-12 | 얀센 파마슈티카 엔.브이. | Pyridine derivatives as fast dissociating dopamine 2 receptor antagonists |
| SI2148873T1 (en) | 2007-04-23 | 2013-01-31 | Janssen Pharmaceutica, N.V. | 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists |
| CA2682671C (en) | 2007-04-23 | 2015-11-17 | Janssen Pharmaceutica N.V. | Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists |
| BRPI0915834A2 (en) | 2008-07-03 | 2015-11-03 | Janssen Pharmaceutica Nv | Substituted 6- (1-piperazinyl) -pyridazines as 5-ht6 receptor antagonists |
| SI2307374T1 (en) | 2008-07-31 | 2017-05-31 | Janssen Pharmaceutica Nv | Piperazin-1-yl-trifluoromethyl-substituted-pyridines as fast dissociating dopamine 2 receptor antagonists |
-
1976
- 1976-09-06 NO NO763054A patent/NO147672C/en unknown
- 1976-09-08 NZ NZ181972A patent/NZ181972A/en unknown
- 1976-09-16 FR FR7627870A patent/FR2325377A1/en active Granted
- 1976-09-17 AU AU17878/76A patent/AU510029B2/en not_active Expired
- 1976-09-20 CA CA261,551A patent/CA1068271A/en not_active Expired
- 1976-09-20 LU LU75837A patent/LU75837A1/xx unknown
- 1976-09-20 RO RO7687590A patent/RO70079A/en unknown
- 1976-09-21 GR GR51742A patent/GR58469B/en unknown
- 1976-09-21 CH CH1194876A patent/CH628623A5/en not_active IP Right Cessation
- 1976-09-21 IT IT51370/76A patent/IT1073893B/en active
- 1976-09-21 GB GB39099/76A patent/GB1539473A/en not_active Expired
- 1976-09-21 JP JP51112527A patent/JPS6016417B2/en not_active Expired
- 1976-09-21 IL IL50522A patent/IL50522A/en unknown
- 1976-09-22 IE IE2095/76A patent/IE43802B1/en unknown
- 1976-09-22 SE SE7610501A patent/SE427839B/en not_active IP Right Cessation
- 1976-09-22 HU HU76JA00000767A patent/HU172964B/en not_active IP Right Cessation
- 1976-09-22 YU YU2336/76A patent/YU39973B/en unknown
- 1976-09-22 PT PT65631A patent/PT65631B/en unknown
- 1976-09-22 CS CS766139A patent/CS222663B2/en unknown
- 1976-09-22 NL NLAANVRAGE7610513,A patent/NL187267C/en not_active IP Right Cessation
- 1976-09-22 FI FI762698A patent/FI61482C/en not_active IP Right Cessation
- 1976-09-22 AT AT0702976A patent/AT363935B/en not_active IP Right Cessation
- 1976-09-22 PL PL19257876A patent/PL192578A1/en not_active IP Right Cessation
- 1976-09-22 DK DK427876A patent/DK150478C/en active
- 1976-09-22 PH PH18928A patent/PH12497A/en unknown
- 1976-09-22 PL PL1976216213A patent/PL117323B1/en unknown
- 1976-09-22 ES ES451768A patent/ES451768A1/en not_active Expired
- 1976-09-23 BG BG034265A patent/BG27543A3/en unknown
- 1976-09-23 SU SU762405548A patent/SU747424A3/en active
- 1976-09-23 DE DE19762642856 patent/DE2642856A1/en active Granted
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