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ID23287A - Trisiklik tersubstitusi - Google Patents

Trisiklik tersubstitusi

Info

Publication number
ID23287A
ID23287A IDP990340D ID990340D ID23287A ID 23287 A ID23287 A ID 23287A ID P990340 D IDP990340 D ID P990340D ID 990340 D ID990340 D ID 990340D ID 23287 A ID23287 A ID 23287A
Authority
ID
Indonesia
Prior art keywords
trisiclic
substituted
substituted trisiclic
Prior art date
Application number
IDP990340D
Other languages
English (en)
Inventor
Benjamin Alan Anderson
Nicholas James Batch
Jolie Anne Bastian
Richard Waltz Harper
Gary Alan Hite
Michael Dean Kinnick
Ho-Shen Nmn Lin
Richard James Loncharich
John Mcneill Mcgill Iii
Edward David Mihelich
John Michael Morin
Michael Leroy Phillips
Michael Enrico Richett
Daniel Jon Sall
Jason Scott Sawyer
Richard Walter Schevitz
Robert Theodore Vasileff
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID23287A publication Critical patent/ID23287A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IDP990340D 1998-04-17 1999-04-15 Trisiklik tersubstitusi ID23287A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6232898A 1998-04-17 1998-04-17

Publications (1)

Publication Number Publication Date
ID23287A true ID23287A (id) 2000-04-05

Family

ID=22041763

Family Applications (2)

Application Number Title Priority Date Filing Date
IDP990341D ID23761A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi
IDP990340D ID23287A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IDP990341D ID23761A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi

Country Status (30)

Country Link
EP (2) EP0952149B1 (id)
JP (2) JPH11322713A (id)
KR (2) KR100586761B1 (id)
CN (1) CN1149193C (id)
AR (2) AR018593A1 (id)
AT (2) ATE271037T1 (id)
AU (2) AU753547B2 (id)
BR (2) BR9901279A (id)
CA (2) CA2269262A1 (id)
CO (2) CO5031247A1 (id)
CZ (2) CZ137099A3 (id)
DE (2) DE69918590T2 (id)
DK (1) DK0950657T3 (id)
DZ (1) DZ2769A1 (id)
EA (2) EA002816B1 (id)
ES (2) ES2222663T3 (id)
HU (2) HUP9901220A3 (id)
ID (2) ID23761A (id)
IL (2) IL129483A0 (id)
NO (2) NO314400B1 (id)
NZ (3) NZ335253A (id)
PE (2) PE20000432A1 (id)
PL (2) PL332565A1 (id)
PT (1) PT950657E (id)
SG (2) SG81976A1 (id)
SI (1) SI0950657T1 (id)
TR (2) TR199900853A2 (id)
TW (1) TWI238160B (id)
YU (2) YU19199A (id)
ZA (2) ZA992771B (id)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1011670A4 (en) * 1997-08-28 2004-10-27 Lilly Co Eli PROCESS FOR TREATING NON-RHUMATOID POLYARTHRITIS
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.
AU1940800A (en) * 1998-12-21 2000-07-12 Eli Lilly And Company Combination therapy for the treatment of sepsis
US6706752B1 (en) 1999-07-19 2004-03-16 Eli Lilly And Company sPLA2 inhibitors
ATE350367T1 (de) * 1999-07-19 2007-01-15 Lilly Co Eli Spla2 inhibitoren
DE60130891T2 (de) * 2000-06-29 2008-07-17 Anthera Pharmaceuticals Inc., San Mateo Heilmittel für krebs
US6967200B2 (en) 2000-06-29 2005-11-22 Shionogi & Co., Ltd. Remedies for cirrhosis
WO2002000257A1 (fr) * 2000-06-29 2002-01-03 Shionogi & Co., Ltd. Remedes a la maladie d'alzheimer
AU2001272915A1 (en) * 2000-07-14 2002-01-30 Eli Lilly And Company Method for treating sepsis
EP1345898A2 (en) 2000-12-18 2003-09-24 Eli Lilly And Company Teracyclic carbazole derivates and their use as spla2 inhibitors
CA2441077A1 (en) * 2001-03-28 2002-10-10 Eli Lilly And Company Substituted carbazoles as inhibitors of spla2
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
DE10249055A1 (de) 2002-10-22 2004-05-06 Bayer Cropscience Ag 2-Phenyl-2-substituierte-1,3-diketone
JO3598B1 (ar) 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
EP1988098A1 (en) * 2007-04-27 2008-11-05 AEterna Zentaris GmbH Novel Tetrahydrocarbazole Derivatives as Ligands of G-protein Coupled Receptors
KR20100124771A (ko) 2008-03-26 2010-11-29 다이이찌 산쿄 가부시키가이샤 신규 테트라하이드로이소퀴놀린 유도체
EP2282742A1 (en) 2008-04-09 2011-02-16 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
EP2379538A4 (en) 2009-01-22 2013-01-02 Orchid Res Lab Ltd HETEROCYCLIC COMPOUNDS AS A PHOSOPHODIESTERASE HEMMER
JP2012523425A (ja) 2009-04-07 2012-10-04 インフイニトイ プハルマセウトイカルス インコーポレイテッド 脂肪酸アミドヒドロラーゼの阻害薬
EP2416660B1 (en) 2009-04-07 2014-07-02 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
JP2013518886A (ja) 2010-02-03 2013-05-23 インフイニトイ プハルマセウトイカルス インコーポレイテッド 脂肪酸アミドヒドロラーゼ阻害剤
AR088377A1 (es) 2011-10-20 2014-05-28 Siena Biotech Spa Proceso para la preparacion de 6-cloro-2,3,4,9-tetrahidro-1h-carbazol-1-carboxamida y compuestos intermedios de esta
CN102816107B (zh) * 2012-08-20 2015-06-03 东南大学 咔唑衍生物及其制备方法与用途
IN2015DN03978A (id) 2012-11-30 2015-10-02 Ge Healthcare Ltd
IN2015DN03939A (id) * 2012-11-30 2015-10-02 Ge Healthcare Ltd
EP3248230B1 (de) * 2015-01-20 2020-05-06 cynora GmbH Verwendung organischer moleküle in optoelektronischen bauelementen
CN108707104A (zh) * 2018-08-07 2018-10-26 北京恒信卓元科技有限公司 2-氯-1h-咔唑-1,4(9h)-二酮的合成方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579534A (en) * 1969-05-09 1971-05-18 American Cyanamid Co Tetrahydrocarbazolecarboxylates
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
US3939177A (en) * 1972-11-22 1976-02-17 Sterling Drug Inc. 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles
US5420289A (en) * 1989-10-27 1995-05-30 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
US5472978A (en) * 1991-07-05 1995-12-05 Merck Sharp & Dohme Ltd. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
DE69610793T2 (de) * 1995-06-23 2001-05-03 Eli Lilly And Co., Indianapolis 6-Subsitituierte-1,2,3,4-tetrahydro-9H-Carbazole und 7-substituierte-1OH-Cyclohepta(7,6-B)-Indole
US6160175A (en) * 1995-12-13 2000-12-12 Eli Lilly And Company Naphthyl acetamides as sPLA2 inhibitors
CZ136899A3 (cs) * 1996-10-30 1999-09-15 Eli Lilly And Company Substituované tricyklické sloučeniny
EP1007056A1 (en) * 1997-09-26 2000-06-14 Eli Lilly And Company Method for the treatment of cystic fibrosis
EP1043991A4 (en) * 1997-11-14 2005-02-02 Lilly Co Eli TREATMENT OF ALZHEIMER DISEASE
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.

Also Published As

Publication number Publication date
ZA992771B (en) 2002-04-18
HU9901220D0 (en) 1999-06-28
AU753547B2 (en) 2002-10-24
KR19990083232A (ko) 1999-11-25
KR19990083233A (ko) 1999-11-25
CA2269262A1 (en) 1999-10-17
AU753436B2 (en) 2002-10-17
NO312240B1 (no) 2002-04-15
EP0952149B1 (en) 2004-06-09
TWI238160B (en) 2005-08-21
HU9901220A (hu) 2000-04-28
DK0950657T3 (da) 2004-11-22
YU19199A (sh) 2002-08-12
DE69918590D1 (de) 2004-08-19
ES2226286T3 (es) 2005-03-16
JP2000026416A (ja) 2000-01-25
EA199900303A2 (ru) 1999-10-28
NO991821L (no) 1999-10-18
HUP9901220A3 (en) 2001-11-28
EP0950657B1 (en) 2004-07-14
AR018186A1 (es) 2001-10-31
KR100586761B1 (ko) 2006-06-08
EP0952149A2 (en) 1999-10-27
AU2381999A (en) 1999-10-28
BR9901279A (pt) 2000-05-02
ATE271037T1 (de) 2004-07-15
CO5031247A1 (es) 2001-04-27
AU2381799A (en) 1999-10-28
TR199900843A2 (xx) 2000-02-21
CA2269246C (en) 2009-08-25
EP0950657A3 (en) 2001-08-16
EA199900303A3 (ru) 2000-04-24
JPH11322713A (ja) 1999-11-24
DE69917833T2 (de) 2005-07-14
AR018593A1 (es) 2001-11-28
EA199900301A2 (ru) 1999-10-28
IL129485A0 (en) 2000-02-29
ZA992772B (en) 2002-07-16
JP4435330B2 (ja) 2010-03-17
NO314400B1 (no) 2003-03-17
HU9901221D0 (en) 1999-06-28
HUP9901221A3 (en) 2001-11-28
PE20000476A1 (es) 2000-06-02
SI0950657T1 (en) 2005-02-28
DE69917833D1 (de) 2004-07-15
EA002347B1 (ru) 2002-04-25
ID23761A (id) 2000-05-11
CA2269246A1 (en) 1999-10-17
TR199900853A3 (tr) 1999-11-22
HU9901221A (hu) 2000-04-28
NZ335253A (en) 2000-11-24
IL129483A0 (en) 2000-02-29
CN1149193C (zh) 2004-05-12
DZ2769A1 (fr) 2003-12-01
PL332566A1 (en) 1999-10-25
NZ507564A (en) 2002-10-25
PE20000432A1 (es) 2000-05-23
DE69918590T2 (de) 2005-07-21
EA002816B1 (ru) 2002-10-31
ES2222663T3 (es) 2005-02-01
SG81977A1 (en) 2001-07-24
EP0950657A2 (en) 1999-10-20
PL332565A1 (en) 1999-10-25
YU18999A (sh) 2002-08-12
NO991822L (no) 1999-10-18
ATE268756T1 (de) 2004-06-15
EA199900301A3 (ru) 2000-04-24
PT950657E (pt) 2004-11-30
NZ335251A (en) 2000-11-24
TR199900853A2 (xx) 1999-11-22
CZ136999A3 (cs) 1999-11-17
NO991822D0 (no) 1999-04-16
BR9902365A (pt) 2001-04-24
EP0952149A3 (en) 2001-08-16
NO991821D0 (no) 1999-04-16
CZ137099A3 (cs) 1999-11-17
SG81976A1 (en) 2001-07-24
CO5011054A1 (es) 2001-02-28
CN1253948A (zh) 2000-05-24

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