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HUT70272A - Recombinant antibodies for human therapy - Google Patents

Recombinant antibodies for human therapy

Info

Publication number
HUT70272A
HUT70272A HU9400201A HU9400201A HUT70272A HU T70272 A HUT70272 A HU T70272A HU 9400201 A HU9400201 A HU 9400201A HU 9400201 A HU9400201 A HU 9400201A HU T70272 A HUT70272 A HU T70272A
Authority
HU
Hungary
Prior art keywords
recombinant antibodies
human therapy
therapy
human
recombinant
Prior art date
Application number
HU9400201A
Other languages
English (en)
Other versions
HU9400201D0 (en
Inventor
Roland A Newman
Nabil Hanna
Ronald W Raab
Original Assignee
Idec Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27112830&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUT70272(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Idec Pharma Corp filed Critical Idec Pharma Corp
Publication of HU9400201D0 publication Critical patent/HU9400201D0/hu
Publication of HUT70272A publication Critical patent/HUT70272A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HU9400201A 1991-07-25 1992-07-24 Recombinant antibodies for human therapy HUT70272A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73506491A 1991-07-25 1991-07-25
US85628192A 1992-03-23 1992-03-23

Publications (2)

Publication Number Publication Date
HU9400201D0 HU9400201D0 (en) 1994-05-30
HUT70272A true HUT70272A (en) 1995-09-28

Family

ID=27112830

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9400201A HUT70272A (en) 1991-07-25 1992-07-24 Recombinant antibodies for human therapy
HU95P/P00595P HU211881A9 (en) 1991-07-25 1995-06-29 Recombinant antibodies for human therapy

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU95P/P00595P HU211881A9 (en) 1991-07-25 1995-06-29 Recombinant antibodies for human therapy

Country Status (24)

Country Link
EP (3) EP0605442B1 (hu)
JP (1) JP3048640B2 (hu)
KR (1) KR0137806B1 (hu)
AP (1) AP307A (hu)
AT (2) ATE327331T1 (hu)
AU (1) AU673499B2 (hu)
BG (1) BG62656B1 (hu)
BR (1) BR9206313A (hu)
CA (1) CA2114015C (hu)
CZ (1) CZ289472B6 (hu)
DE (2) DE69233628T2 (hu)
DK (2) DK1266965T3 (hu)
ES (2) ES2196002T3 (hu)
FI (1) FI117703B (hu)
HU (2) HUT70272A (hu)
IL (1) IL102640A0 (hu)
MY (1) MY121185A (hu)
NO (1) NO318097B1 (hu)
NZ (1) NZ243706A (hu)
OA (1) OA09879A (hu)
PT (1) PT100735B (hu)
RO (1) RO116404B1 (hu)
SK (2) SK285960B6 (hu)
WO (1) WO1993002108A1 (hu)

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US6284471B1 (en) 1991-03-18 2001-09-04 New York University Medical Center Anti-TNFa antibodies and assays employing anti-TNFa antibodies
US5919452A (en) * 1991-03-18 1999-07-06 New York University Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies
US6277969B1 (en) 1991-03-18 2001-08-21 New York University Anti-TNF antibodies and peptides of human tumor necrosis factor
CA2111858A1 (en) * 1991-07-15 1993-02-04 James S. Crowe Production of antibodies
US6136310A (en) 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
US7744877B2 (en) 1992-11-13 2010-06-29 Biogen Idec Inc. Expression and use of anti-CD20 Antibodies
DK0669836T3 (da) 1992-11-13 1996-10-14 Idec Pharma Corp Terapeutisk anvendelse af kimære og radioaktivt mærkede antistoffer og humant B-lymfocytbegrænset differentieringsantigen til behandling af B-cellelymfom
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US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
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CA2206471A1 (en) * 1994-12-07 1996-06-13 Hoffmann-La Roche Inc. Monoclonal antibody fragments having immunosuppressant activity
US6113898A (en) 1995-06-07 2000-09-05 Idec Pharmaceuticals Corporation Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
US7153508B2 (en) 1995-06-07 2006-12-26 Biogen Idec Inc. Treatment of B cell lymphoma using anti-CD80 antibodies that do not inhibit the binding of CD80 to CTLA-4
US7175847B1 (en) 1995-06-07 2007-02-13 Biogen Idec Inc. Treating intestinal inflammation with anti-CD80 antibodies that do not inhibit CD80 binding to CTLA-4
GB9624038D0 (en) * 1996-11-19 1997-01-08 Sandoz Ltd Organic compounds
US7033589B1 (en) 1997-02-20 2006-04-25 Biogen Idec Ma Inc. γ-1 anti-human CD23 monoclonal antibodies and use thereof as therapeutics
US6893636B2 (en) * 1997-02-20 2005-05-17 Biogen Idec Ma Inc. Gamma-1 and gamma-3 anti-human CD23 monoclonal antibodies and use thereof as therapeutics
US6011138A (en) * 1997-02-20 2000-01-04 Idec Pharmaceuticals Corporation Gamma-1 anti-human CD23 monoclonal antibodies
WO1999055369A1 (en) 1998-04-28 1999-11-04 Smithkline Beecham Corporation Monoclonal antibodies with reduced immunogenicity
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EP1946775A3 (en) 1998-08-11 2008-08-06 Biogen Idec Inc. Combination therapies for B-cell lymphomas comprising administration of anti-CD20 antibody
US7682612B1 (en) 1998-11-09 2010-03-23 Biogen Idec Inc. Treatment of hematologic malignancies associated with circulating tumor cells using chimeric anti-CD20 antibody
CA2372603C (en) 1999-05-07 2015-11-17 Genentech, Inc. Treatment of autoimmune diseases with antagonists which bind to b cell surface markers
US8557244B1 (en) 1999-08-11 2013-10-15 Biogen Idec Inc. Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
AU2001271614B2 (en) * 2000-07-03 2007-05-31 Catalent Pharma Solutions, Llc Host cells containing multiple integrating vectors
JP4762478B2 (ja) * 2000-07-03 2011-08-31 キャタレント ファーマ ソリューションズ リミテッド ライアビリティ カンパニー 発現ベクター
EP2151493B1 (en) * 2000-07-03 2012-06-13 Catalent Pharma Solutions, LLC Host cells containing multiple integrating vectors
UA81743C2 (uk) 2000-08-07 2008-02-11 Центокор, Инк. МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
US20050101012A1 (en) 2001-03-12 2005-05-12 Gerold Schuler CD4+CD25+ regulatory T cells from human blood
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CN1902228A (zh) * 2003-11-07 2007-01-24 安姆根有限公司 猴免疫球蛋白序列
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KR101671537B1 (ko) 2008-08-11 2016-11-01 넥타르 테라퓨틱스 다분지형 중합체 알카노에이트 컨쥬게이트
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WO2012088422A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
US10894087B2 (en) 2010-12-22 2021-01-19 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
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US20240301070A1 (en) 2020-06-04 2024-09-12 Bioinvent International Ab Improving antibody tolerability associated with intravenous administration
CA3210609A1 (en) 2021-03-09 2022-09-15 Bjorn Frendeus Novel combinations of antibodies and uses thereof
EP4482860A1 (en) * 2022-02-24 2025-01-01 AbnomX BV Human-like target-binding proteins
TW202336033A (zh) 2022-03-07 2023-09-16 瑞典商生物創新國際有限公司 抗體之新穎組合及用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2111858A1 (en) * 1991-07-15 1993-02-04 James S. Crowe Production of antibodies

Also Published As

Publication number Publication date
EP0605442A4 (en) 1995-07-12
EP0605442B1 (en) 2003-04-16
DE69233628D1 (de) 2006-06-29
WO1993002108A1 (en) 1993-02-04
BR9206313A (pt) 1995-04-11
AP307A (en) 1994-01-31
CA2114015A1 (en) 1993-02-04
KR0137806B1 (ko) 1998-04-30
FI940336A0 (fi) 1994-01-24
NO940219D0 (no) 1994-01-21
AP9200413A0 (en) 1992-07-31
DK1266965T3 (da) 2006-09-25
SK285046B6 (sk) 2006-05-04
ATE327331T1 (de) 2006-06-15
DE69233628T2 (de) 2007-04-26
ES2265005T3 (es) 2007-02-01
HU211881A9 (en) 1995-12-28
NO318097B1 (no) 2005-01-31
JPH06509708A (ja) 1994-11-02
EP1715045A3 (en) 2006-12-13
IL102640A0 (en) 1993-01-14
BG62656B1 (bg) 2000-04-28
CZ289472B6 (cs) 2002-01-16
OA09879A (en) 1994-09-15
FI940336A (fi) 1994-03-10
DE69233011T2 (de) 2003-11-06
EP1266965A2 (en) 2002-12-18
ES2196002T3 (es) 2003-12-16
FI117703B (fi) 2007-01-31
CA2114015C (en) 2002-12-10
PT100735B (pt) 1999-07-30
SK8894A3 (en) 1994-09-07
CZ14994A3 (en) 1994-07-13
NO940219L (no) 1994-03-25
ATE237638T1 (de) 2003-05-15
HU9400201D0 (en) 1994-05-30
SK285960B6 (sk) 2007-12-06
EP1266965B1 (en) 2006-05-24
PT100735A (pt) 1993-10-29
JP3048640B2 (ja) 2000-06-05
EP1715045A2 (en) 2006-10-25
AU673499B2 (en) 1996-11-14
AU2425592A (en) 1993-02-23
DE69233011D1 (de) 2003-05-22
RO116404B1 (ro) 2001-01-30
BG98411A (bg) 1995-02-28
EP0605442A1 (en) 1994-07-13
EP1266965A3 (en) 2003-01-02
DK0605442T3 (da) 2003-08-04
NZ243706A (en) 1994-08-26
MY121185A (en) 2006-01-28

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