HUT43561A - Process for preparing novel carbacyclines and pharmaceutics comprising such compounds - Google Patents
Process for preparing novel carbacyclines and pharmaceutics comprising such compoundsInfo
- Publication number
- HUT43561A HUT43561A HU865587A HU558786A HUT43561A HU T43561 A HUT43561 A HU T43561A HU 865587 A HU865587 A HU 865587A HU 558786 A HU558786 A HU 558786A HU T43561 A HUT43561 A HU T43561A
- Authority
- HU
- Hungary
- Prior art keywords
- carbacyclines
- pharmaceutics
- compounds
- group
- preparing novel
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- -1 amino, methylamino, hydroxy, carboxy Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853542745 DE3542745A1 (de) | 1985-11-29 | 1985-11-29 | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| PCT/DE1986/000484 WO1987003283A1 (en) | 1985-11-29 | 1986-11-28 | New carbacyclines, process for their production and their use as medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUT43561A true HUT43561A (en) | 1987-11-30 |
Family
ID=6287504
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU8755Q HU206317B (en) | 1985-11-29 | 1986-11-28 | Process for producing carbacyclines and pharmaceutical compositions containing them |
| HU865587A HUT43561A (en) | 1985-11-29 | 1986-11-28 | Process for preparing novel carbacyclines and pharmaceutics comprising such compounds |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU8755Q HU206317B (en) | 1985-11-29 | 1986-11-28 | Process for producing carbacyclines and pharmaceutical compositions containing them |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0224275B1 (hu) |
| JP (1) | JPS63501871A (hu) |
| AT (1) | ATE55119T1 (hu) |
| AU (1) | AU605127B2 (hu) |
| CA (1) | CA1275095A (hu) |
| DE (2) | DE3542745A1 (hu) |
| DK (1) | DK396387D0 (hu) |
| ES (1) | ES2036170T3 (hu) |
| GR (1) | GR3000884T3 (hu) |
| HU (2) | HU206317B (hu) |
| IE (1) | IE59345B1 (hu) |
| WO (1) | WO1987003283A1 (hu) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3725031A1 (de) * | 1987-07-24 | 1989-02-02 | Schering Ag | Neue 9-substituierte carbacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US5374654A (en) * | 1987-07-24 | 1994-12-20 | Schering Aktiengesellschaft | 9-substituted carbacyclin derivatives, processes for their preparation, and their use as medicinal agents |
| DE4134156A1 (de) * | 1991-10-11 | 1993-04-15 | Schering Ag | 9-substituierte bicyclo(3.3.0)octan-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5215949B1 (hu) * | 1970-06-15 | 1977-05-06 | ||
| US4420632A (en) * | 1980-04-15 | 1983-12-13 | The Upjohn Company | Composition and process |
| US4588823A (en) * | 1982-02-16 | 1986-05-13 | The Upjohn Company | 9-substituted carbacyclin analogs |
| US4487961A (en) * | 1982-02-16 | 1984-12-11 | The Upjohn Company | 9-Substituted carbacyclin analogs |
| DE3428266A1 (de) * | 1984-07-27 | 1986-01-30 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
-
1985
- 1985-11-29 DE DE19853542745 patent/DE3542745A1/de not_active Withdrawn
-
1986
- 1986-11-10 CA CA000522586A patent/CA1275095A/en not_active Expired
- 1986-11-28 ES ES198686116566T patent/ES2036170T3/es not_active Expired - Lifetime
- 1986-11-28 HU HU8755Q patent/HU206317B/hu not_active IP Right Cessation
- 1986-11-28 JP JP62500022A patent/JPS63501871A/ja active Pending
- 1986-11-28 WO PCT/DE1986/000484 patent/WO1987003283A1/de unknown
- 1986-11-28 IE IE313086A patent/IE59345B1/en not_active IP Right Cessation
- 1986-11-28 EP EP86116566A patent/EP0224275B1/de not_active Expired - Lifetime
- 1986-11-28 AU AU67249/87A patent/AU605127B2/en not_active Ceased
- 1986-11-28 HU HU865587A patent/HUT43561A/hu unknown
- 1986-11-28 AT AT86116566T patent/ATE55119T1/de not_active IP Right Cessation
- 1986-11-28 DE DE8686116566T patent/DE3673135D1/de not_active Expired - Lifetime
-
1987
- 1987-07-29 DK DK396387A patent/DK396387D0/da not_active Application Discontinuation
-
1990
- 1990-09-28 GR GR90400561T patent/GR3000884T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3000884T3 (en) | 1991-11-15 |
| AU605127B2 (en) | 1991-01-10 |
| ES2036170T3 (es) | 1993-05-16 |
| AU6724987A (en) | 1987-07-01 |
| DK396387A (da) | 1987-07-29 |
| ATE55119T1 (de) | 1990-08-15 |
| DE3673135D1 (de) | 1990-09-06 |
| DE3542745A1 (de) | 1987-08-06 |
| CA1275095A (en) | 1990-10-09 |
| JPS63501871A (ja) | 1988-07-28 |
| DK396387D0 (da) | 1987-07-29 |
| EP0224275A1 (de) | 1987-06-03 |
| EP0224275B1 (de) | 1990-08-01 |
| WO1987003283A1 (en) | 1987-06-04 |
| IE59345B1 (en) | 1994-02-09 |
| IE863130L (en) | 1987-05-29 |
| HU206317B (en) | 1992-10-28 |
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