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HUP0004507A1 - Ketolidok alkalmazása atheroszklerózissal kapcsolatos artériás trombózis- komplikációk megelőzésére alkalmas gyógyszerkészítmény előállítására - Google Patents

Ketolidok alkalmazása atheroszklerózissal kapcsolatos artériás trombózis- komplikációk megelőzésére alkalmas gyógyszerkészítmény előállítására

Info

Publication number
HUP0004507A1
HUP0004507A1 HU0004507A HUP0004507A HUP0004507A1 HU P0004507 A1 HUP0004507 A1 HU P0004507A1 HU 0004507 A HU0004507 A HU 0004507A HU P0004507 A HUP0004507 A HU P0004507A HU P0004507 A1 HUP0004507 A1 HU P0004507A1
Authority
HU
Hungary
Prior art keywords
ketolides
atherosclerosis
complications related
group
thrombotic complications
Prior art date
Application number
HU0004507A
Other languages
English (en)
Inventor
Francis Petit
Francoise Vacheron
Original Assignee
Hoechst Marion Roussel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel
Publication of HUP0004507A1 publication Critical patent/HUP0004507A1/hu
Publication of HUP0004507A3 publication Critical patent/HUP0004507A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

A találmány tárgya ketolidok alkalmazása atheroszklerózissalkapcsolatos artériás trombózis komplikációk megelőzésére alkalmasgyógyszerkészítmény előállítására. Ketolidként előnyösen (I) általánosképletű vegyületet használnak, a képletben R jelentése -(CH2)mOn(X)YAráltalános képletű csoport, ahol m értéke 0 vagy 1, n értéke 0 vagy 1,X jelentése -(NH)a-, -CH2- vagy -SO2- képletű csoport, ahol a értéke 0vagy 1, Y jelentése -(CH2)b-(CH=CH)c-(CH2)d- általános képletűcsoport, ahol c értéke 0 vagy 1 és b+c+d összege 8, Z jelentésehidrogén- vagy halogénatom, Ar jelentése adott esetben helyettesítettaril- vagy heteroaril-csoport. Ó
HU0004507A 1997-11-17 1998-11-16 Use of ketolides preparing arterial thrombotic complications related to atherosclerosis HUP0004507A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714358A FR2771008B1 (fr) 1997-11-17 1997-11-17 Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
PCT/FR1998/002436 WO1999025365A1 (fr) 1997-11-17 1998-11-16 Utilisation des ketolides pour prevenir les complications thrombotiques arterielles liees a l'atherosclerose

Publications (2)

Publication Number Publication Date
HUP0004507A1 true HUP0004507A1 (hu) 2001-05-28
HUP0004507A3 HUP0004507A3 (en) 2001-12-28

Family

ID=9513423

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004507A HUP0004507A3 (en) 1997-11-17 1998-11-16 Use of ketolides preparing arterial thrombotic complications related to atherosclerosis

Country Status (35)

Country Link
US (1) US20080139489A1 (hu)
EP (1) EP1030673B1 (hu)
JP (1) JP4550273B2 (hu)
KR (1) KR20010032130A (hu)
CN (1) CN1286633A (hu)
AP (1) AP1196A (hu)
AR (1) AR014119A1 (hu)
AT (1) ATE271875T1 (hu)
AU (1) AU744419B2 (hu)
BG (1) BG104427A (hu)
BR (1) BR9814199A (hu)
CA (1) CA2312021C (hu)
DE (1) DE69825308T2 (hu)
DZ (1) DZ2654A1 (hu)
EA (1) EA003322B1 (hu)
EE (1) EE04095B1 (hu)
ES (1) ES2224446T3 (hu)
FR (1) FR2771008B1 (hu)
GE (1) GEP20032968B (hu)
HR (1) HRP20000314A2 (hu)
HU (1) HUP0004507A3 (hu)
ID (1) ID24940A (hu)
IL (1) IL136149A0 (hu)
MA (1) MA26566A1 (hu)
NO (1) NO20002435L (hu)
NZ (1) NZ504305A (hu)
OA (1) OA11411A (hu)
PL (1) PL340373A1 (hu)
SK (1) SK7042000A3 (hu)
TN (1) TNSN98206A1 (hu)
TR (1) TR200001384T2 (hu)
TW (1) TW472061B (hu)
WO (1) WO1999025365A1 (hu)
YU (1) YU29600A (hu)
ZA (1) ZA9810357B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2777282B1 (fr) * 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
WO2000034297A1 (en) 1998-12-10 2000-06-15 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
ES2212655T3 (es) * 1999-01-27 2004-07-16 Pfizer Products Inc. Antibioticos de cetolidos.
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
PL358666A1 (en) 2000-04-04 2004-08-09 Smithkline Beecham Plc 2-hydroxy-mutilin carbamate derivatives for antibacterial use
JP2004323414A (ja) * 2003-04-24 2004-11-18 Japan Science & Technology Agency １４員環マクロライド化合物を利用した、血管平滑筋の増殖に起因する疾患治療剤
GB0402578D0 (en) * 2004-02-05 2004-03-10 Cambridge Theranostics Ltd Methods of treatment of atherosclerosis
KR20180110181A (ko) * 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5424187A (en) * 1991-06-14 1995-06-13 Board Of Regents Of The University Of Washington Method of screening for arterial chlamydial granuloma
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6271255B1 (en) * 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
GB9621771D0 (en) * 1996-10-18 1996-12-11 St George S Enterprises Ltd Method of treatment of heart disease
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics

Also Published As

Publication number Publication date
TR200001384T2 (tr) 2001-06-21
WO1999025365A1 (fr) 1999-05-27
HUP0004507A3 (en) 2001-12-28
US20080139489A1 (en) 2008-06-12
AP2000001825A0 (en) 2000-06-30
TW472061B (en) 2002-01-11
ZA9810357B (en) 1999-11-12
OA11411A (fr) 2004-04-20
JP2001523644A (ja) 2001-11-27
EE200000244A (et) 2001-06-15
YU29600A (sh) 2003-02-28
FR2771008B1 (fr) 2000-04-28
EP1030673B1 (fr) 2004-07-28
AR014119A1 (es) 2001-02-07
BG104427A (en) 2001-02-28
FR2771008A1 (fr) 1999-05-21
SK7042000A3 (en) 2000-12-11
PL340373A1 (en) 2001-01-29
MA26566A1 (fr) 2004-12-20
NZ504305A (en) 2002-11-26
EA200000531A1 (ru) 2000-10-30
ATE271875T1 (de) 2004-08-15
CA2312021A1 (fr) 1999-05-27
AU744419B2 (en) 2002-02-21
AU1242599A (en) 1999-06-07
EE04095B1 (et) 2003-08-15
ES2224446T3 (es) 2005-03-01
AP1196A (en) 2003-08-18
CA2312021C (fr) 2008-08-26
DZ2654A1 (fr) 2003-03-22
IL136149A0 (en) 2001-05-20
NO20002435D0 (no) 2000-05-11
HRP20000314A2 (en) 2001-02-28
EA003322B1 (ru) 2003-04-24
DE69825308T2 (de) 2005-08-04
TNSN98206A1 (fr) 2005-03-15
KR20010032130A (ko) 2001-04-16
ID24940A (id) 2000-08-31
JP4550273B2 (ja) 2010-09-22
GEP20032968B (en) 2003-05-27
CN1286633A (zh) 2001-03-07
BR9814199A (pt) 2000-09-26
DE69825308D1 (de) 2004-09-02
NO20002435L (no) 2000-07-07
EP1030673A1 (fr) 2000-08-30

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