HRP20130585T1 - Alkylthiazol carbamate derivatives, preparation thereof and their use as faah inhibitors - Google Patents

Alkylthiazol carbamate derivatives, preparation thereof and their use as faah inhibitors

Info

Publication number: HRP20130585T1
Authority: HR; Croatia
Prior art keywords: alkylthiazol; preparation; carbamate derivatives; faah inhibitors; faah
Prior art date: 2008-07-23

Application number

HRP20130585AT

Other languages

English (en)

Inventor

Ahmed Abouabdellah

Jochen GÖRLITZER

Peter Hamley

Antoine Ravet

Original Assignee

Sanofi

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-23

Filing date

2013-06-26

Publication date

2013-07-31

2013-06-26 Application filed by Sanofi filed Critical Sanofi

2013-07-31 Publication of HRP20130585T1 publication Critical patent/HRP20130585T1/hr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Oncology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Psychology (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Tropical Medicine & Parasitology (AREA)
Otolaryngology (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Obesity (AREA)

HRP20130585AT 2008-07-23 2013-06-26 Alkylthiazol carbamate derivatives, preparation thereof and their use as faah inhibitors HRP20130585T1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0804179A FR2934265B1 (fr)	2008-07-23	2008-07-23	Derives de carbamates d'alkylthiazoles, leur preparation et leur application en therapeutique
PCT/FR2009/051457 WO2010010288A2 (fr)	2008-07-23	2009-07-21	Derives de carbamates d'alkylthiazoles, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
HRP20130585T1 true HRP20130585T1 (en)	2013-07-31

Family

ID=40289184

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HRP20130585AT HRP20130585T1 (en)	2008-07-23	2013-06-26	Alkylthiazol carbamate derivatives, preparation thereof and their use as faah inhibitors

Country Status (28)

Country	Link
US (1)	US8912218B2 (hr)
EP (1)	EP2344486B1 (hr)
JP (1)	JP5452594B2 (hr)
KR (1)	KR20110034020A (hr)
CN (1)	CN102164920B (hr)
AR (1)	AR072593A1 (hr)
AU (1)	AU2009274355B2 (hr)
BR (1)	BRPI0916385A2 (hr)
CA (1)	CA2731789C (hr)
CL (1)	CL2011000147A1 (hr)
CO (1)	CO6351789A2 (hr)
CY (1)	CY1114519T1 (hr)
DK (1)	DK2344486T3 (hr)
EA (1)	EA018995B1 (hr)
ES (1)	ES2413304T3 (hr)
FR (1)	FR2934265B1 (hr)
HR (1)	HRP20130585T1 (hr)
IL (1)	IL210747A0 (hr)
MA (1)	MA32579B1 (hr)
MX (1)	MX2011000882A (hr)
PE (1)	PE20110384A1 (hr)
PL (1)	PL2344486T3 (hr)
PT (1)	PT2344486E (hr)
SI (1)	SI2344486T1 (hr)
SM (1)	SMT201300080B (hr)
TW (1)	TW201008937A (hr)
UY (1)	UY32004A (hr)
WO (1)	WO2010010288A2 (hr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2938537B1 (fr) *	2008-11-14	2012-10-26	Sanofi Aventis	Derives de carbamates d'alkyl-heterocycles, leur preparation et leur application en therapeutique.
FR2941696B1 (fr) *	2009-02-05	2011-04-15	Sanofi Aventis	Derives d'azaspiranyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
FR2945533B1 (fr) *	2009-05-12	2011-05-27	Sanofi Aventis	Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
FR2945534B1 (fr) *	2009-05-12	2012-11-16	Sanofi Aventis	DERIVES DE CYCLOPENTAL[c]PYRROLE-2-CARBOXYLATES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
WO2011085216A2 (en)	2010-01-08	2011-07-14	Ironwood Pharmaceuticals, Inc.	Use of faah inhibitors for treating parkinson's disease and restless legs syndrome
US20130224151A1 (en)	2010-03-31	2013-08-29	United States Of America	Use of FAAH Inhibitors for Treating Abdominal, Visceral and Pelvic Pain
CN103209695A (zh)	2010-09-15	2013-07-17	弗·哈夫曼-拉罗切有限公司	氮杂苯并噻唑化合物、组合物及应用方法
DE102012018115A1 (de)	2012-09-13	2014-03-13	Matthias Lehr	Aryl-N-(arylalkyl)carbamate als Hemmstoffe der Fatty Acid Amide Hydrolase
DE102013016573A1 (de)	2013-10-04	2015-04-09	Matthias Lehr	1-Tetrazolylpropan-2-one als Inhibitoren von cytosolischer Phospholipase A2 und Fatty Acid Amide Hydrolase, insbesondere geeignet zur topischen Anwendung
WO2020048828A1 (en)	2018-09-03	2020-03-12	Bayer Pharma Aktiengesellschaft	5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds
WO2020048831A1 (en)	2018-09-03	2020-03-12	Bayer Aktiengesellschaft	5-aryl-3,9-diazaspiro[5.5]undecan-2-one compounds
WO2020048830A1 (en)	2018-09-03	2020-03-12	Bayer Aktiengesellschaft	5-aryl-3,9-diazaspiro[5.5]undecan-2-one compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2854633B1 (fr) *	2003-05-07	2005-06-24	Sanofi Synthelabo	Derives de piperidinyl-et piperazinyl-alkylcarbamates, leur preparation et leur application en therapeutique
GB0417801D0 (en) *	2004-08-10	2004-09-15	Novartis Ag	Organic compounds
CA2575039A1 (en) *	2004-08-11	2006-02-16	Kyorin Pharmaceutical Co., Ltd.	Novel cyclic amino benzoic acid derivative
TWI444379B (zh) *	2007-06-29	2014-07-11	Sunesis Pharmaceuticals Inc	有用於作為Ｒａｆ激酶抑制劑之化合物
FR2938537B1 (fr) *	2008-11-14	2012-10-26	Sanofi Aventis	Derives de carbamates d'alkyl-heterocycles, leur preparation et leur application en therapeutique.

2008
- 2008-07-23 FR FR0804179A patent/FR2934265B1/fr not_active Expired - Fee Related
2009
- 2009-07-21 KR KR1020117004019A patent/KR20110034020A/ko not_active Application Discontinuation
- 2009-07-21 DK DK09737098.5T patent/DK2344486T3/da active
- 2009-07-21 PT PT97370985T patent/PT2344486E/pt unknown
- 2009-07-21 JP JP2011519216A patent/JP5452594B2/ja not_active Expired - Fee Related
- 2009-07-21 BR BRPI0916385-9A patent/BRPI0916385A2/pt not_active IP Right Cessation
- 2009-07-21 ES ES09737098T patent/ES2413304T3/es active Active
- 2009-07-21 EP EP09737098A patent/EP2344486B1/fr active Active
- 2009-07-21 MX MX2011000882A patent/MX2011000882A/es active IP Right Grant
- 2009-07-21 CA CA2731789A patent/CA2731789C/fr not_active Expired - Fee Related
- 2009-07-21 SI SI200930624T patent/SI2344486T1/sl unknown
- 2009-07-21 PE PE2011000070A patent/PE20110384A1/es not_active Application Discontinuation
- 2009-07-21 US US13/003,713 patent/US8912218B2/en not_active Expired - Fee Related
- 2009-07-21 EA EA201170237A patent/EA018995B1/ru not_active IP Right Cessation
- 2009-07-21 WO PCT/FR2009/051457 patent/WO2010010288A2/fr active Application Filing
- 2009-07-21 PL PL09737098T patent/PL2344486T3/pl unknown
- 2009-07-21 AU AU2009274355A patent/AU2009274355B2/en not_active Ceased
- 2009-07-21 CN CN2009801372742A patent/CN102164920B/zh not_active Expired - Fee Related
- 2009-07-22 AR ARP090102787A patent/AR072593A1/es not_active Application Discontinuation
- 2009-07-22 TW TW098124759A patent/TW201008937A/zh unknown
- 2009-07-23 UY UY0001032004A patent/UY32004A/es not_active Application Discontinuation
2011
- 2011-01-19 IL IL210747A patent/IL210747A0/en unknown
- 2011-01-20 CO CO11005623A patent/CO6351789A2/es not_active Application Discontinuation
- 2011-01-21 CL CL2011000147A patent/CL2011000147A1/es unknown
- 2011-02-22 MA MA33636A patent/MA32579B1/fr unknown
2013
- 2013-06-26 HR HRP20130585AT patent/HRP20130585T1/hr unknown
- 2013-06-27 CY CY20131100519T patent/CY1114519T1/el unknown
- 2013-07-15 SM SM201300080T patent/SMT201300080B/xx unknown

Also Published As

Publication number	Publication date
WO2010010288A2 (fr)	2010-01-28
ES2413304T3 (es)	2013-07-16
PT2344486E (pt)	2013-06-27
CL2011000147A1 (es)	2011-06-17
SMT201300080B (it)	2013-09-06
PE20110384A1 (es)	2011-07-01
MX2011000882A (es)	2011-03-01
EA201170237A1 (ru)	2011-10-31
FR2934265A1 (fr)	2010-01-29
KR20110034020A (ko)	2011-04-04
CA2731789A1 (fr)	2010-01-28
BRPI0916385A2 (pt)	2018-06-05
AU2009274355A1 (en)	2010-01-28
EP2344486B1 (fr)	2013-03-27
CO6351789A2 (es)	2011-12-20
CN102164920A (zh)	2011-08-24
JP5452594B2 (ja)	2014-03-26
MA32579B1 (fr)	2011-08-01
UY32004A (es)	2010-02-26
FR2934265B1 (fr)	2010-07-30
CY1114519T1 (el)	2016-10-05
AR072593A1 (es)	2010-09-08
WO2010010288A3 (fr)	2010-03-18
PL2344486T3 (pl)	2013-08-30
EA018995B1 (ru)	2013-12-30
EP2344486A2 (fr)	2011-07-20
US20110212963A1 (en)	2011-09-01
DK2344486T3 (da)	2013-07-08
JP2011528704A (ja)	2011-11-24
AU2009274355B2 (en)	2014-01-30
IL210747A0 (en)	2011-03-31
TW201008937A (en)	2010-03-01
US8912218B2 (en)	2014-12-16
CN102164920B (zh)	2013-12-25
CA2731789C (fr)	2016-08-30
SI2344486T1 (sl)	2013-07-31

Publication	Publication Date	Title
HRP20130585T1 (en)	2013-07-31	Alkylthiazol carbamate derivatives, preparation thereof and their use as faah inhibitors
HUS1700034I1 (hu)	2017-09-28	Izoxazolin-származékok és peszticidként történõ alkalmazásuk
IL239833A0 (en)	2015-08-31	Iminothiadiazine dioxide compounds, their preparations and uses
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