HRP20100113T1 - Upotreba pripravaka koji sadrže antagonist kapa-opioidnog receptora, namijenjenih liječenju disocijativnih poremećaja - Google Patents
Upotreba pripravaka koji sadrže antagonist kapa-opioidnog receptora, namijenjenih liječenju disocijativnih poremećaja Download PDFInfo
- Publication number
- HRP20100113T1 HRP20100113T1 HR20100113T HRP20100113T HRP20100113T1 HR P20100113 T1 HRP20100113 T1 HR P20100113T1 HR 20100113 T HR20100113 T HR 20100113T HR P20100113 T HRP20100113 T HR P20100113T HR P20100113 T1 HRP20100113 T1 HR P20100113T1
- Authority
- HR
- Croatia
- Prior art keywords
- opioid receptor
- receptor antagonist
- treatment
- containing compositions
- kappa opioid
- Prior art date
Links
- 239000002618 kappa opiate receptor antagonist Substances 0.000 title claims abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000018459 dissociative disease Diseases 0.000 title 1
- 239000005557 antagonist Substances 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 150000002148 esters Chemical class 0.000 claims abstract 2
- 150000004677 hydrates Chemical class 0.000 claims abstract 2
- 238000004519 manufacturing process Methods 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 229940123257 Opioid receptor antagonist Drugs 0.000 claims 2
- 239000003401 opiate antagonist Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 1
- 150000002170 ethers Chemical class 0.000 claims 1
- UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical group O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 claims 1
- 229960004127 naloxone Drugs 0.000 claims 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Upotreba pripravka koji sadrži antagonist kapa-opioidnog receptora sljedeće formule, naznačena time što je navedeni antagonist namijenjen proizvodnji lijeka za liječenje emocionalno nestabilne ličnosti (F60.3 u ICD-10) kod ljudi: ili njegove farmaceutski prihvatljive soli, estere, etere i/ili hidrate. Patent sadrži još 2 patentna zahtjeva.
Claims (3)
1. Upotreba pripravka koji sadrži antagonist kapa-opioidnog receptora sljedeće formule, naznačena time što je navedeni antagonist namijenjen proizvodnji lijeka za liječenje emocionalno nestabilne ličnosti (F60.3 u ICD-10) kod ljudi:
[image]
ili njegove farmaceutski prihvatljive soli, estere, etere i/ili hidrate.
2. Upotreba u skladu s patentnim zahtjevom 1, naznačena time što pripravak također sadrži antagonist opioidnih receptora.
3. Upotreba u skladu s prethodnim patentnim zahtjevom, naznačena time što antagonist opioidnih receptora je nalokson.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006015733A DE102006015733A1 (de) | 2006-04-04 | 2006-04-04 | Verwendung von Buprenorphin und Buprenorphin-Derivaten zur Herstellung eines Medikaments zur Behandlung von emotional instabiler Persönlichkeitsstörung, Alkoholabhängigkeit und/oder multipler Substanzabhängigkeit |
DE102006016991A DE102006016991A1 (de) | 2006-04-11 | 2006-04-11 | Verwendung von kappa-Opioidrezeptor-Antagonisten zur Behandlung von dissoziativen Störungen |
PCT/EP2007/053248 WO2007115975A2 (de) | 2006-04-04 | 2007-04-03 | Verwendung von zusammensetzungen enthaltend kappa-opioidrezeptor-antagonisten zur behandlung von dissoziativen störungen |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20100113T1 true HRP20100113T1 (hr) | 2010-04-30 |
Family
ID=38110094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20100113T HRP20100113T1 (hr) | 2006-04-04 | 2010-03-02 | Upotreba pripravaka koji sadrže antagonist kapa-opioidnog receptora, namijenjenih liječenju disocijativnih poremećaja |
Country Status (17)
Country | Link |
---|---|
US (1) | US8063059B2 (hr) |
EP (1) | EP2001456B1 (hr) |
JP (1) | JP5128578B2 (hr) |
AT (1) | ATE450256T1 (hr) |
AU (1) | AU2007236003B2 (hr) |
CA (1) | CA2646899C (hr) |
CY (1) | CY1109862T1 (hr) |
DE (1) | DE502007002185D1 (hr) |
DK (1) | DK2001456T3 (hr) |
EA (1) | EA014820B1 (hr) |
ES (1) | ES2337622T3 (hr) |
HR (1) | HRP20100113T1 (hr) |
PL (1) | PL2001456T3 (hr) |
PT (1) | PT2001456E (hr) |
RS (1) | RS51211B (hr) |
SI (1) | SI2001456T1 (hr) |
WO (1) | WO2007115975A2 (hr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI422369B (zh) | 2008-01-22 | 2014-01-11 | Lilly Co Eli | κ選擇性類鴉片受體拮抗劑 |
EP3082816B1 (en) | 2013-12-20 | 2019-03-20 | Indivior UK Limited | Intranasal naloxone compositions and methods of making and using same |
ES2694352T3 (es) * | 2013-12-20 | 2018-12-20 | H. Lundbeck A/S | Uso de un antagonista del receptor opioide con actividad kappa, y vortioxetina para el tratamiento del trastorno depresivo con características melancólicas |
ES2658766T3 (es) | 2014-04-28 | 2018-03-12 | Orphomed, Inc. | Dímero de buprenorfina y uso en el tratamiento de trastornos gastrointestinales |
US10316021B2 (en) | 2016-11-28 | 2019-06-11 | Pfizer Inc. | Heteroarylphenoxy benzamide kappa opioid ligands |
US20220370409A1 (en) | 2021-05-04 | 2022-11-24 | Janssen Pharmaceuticals, Inc. | Compositions And Methods For The Treatment Of Depression |
TW202345796A (zh) | 2022-03-07 | 2023-12-01 | 美商健生醫藥公司 | 阿替卡普蘭(aticaprant)之形式 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5028612A (en) | 1990-03-22 | 1991-07-02 | Hillel Glover | Method for treating emotional numbness |
US5780479A (en) * | 1997-04-04 | 1998-07-14 | Regents Of The University Of Minnesota | Use of opioid antagonists to treat impulse-control disorders |
WO1999045906A1 (en) | 1998-03-09 | 1999-09-16 | Trustees Of Tufts College | Treatment of compulsive behaviours in man and animals |
EP1365756A2 (en) | 2000-08-15 | 2003-12-03 | Cpd, Llc | Method of treating the syndrome of type 2 diabetes in humans |
US20020045572A1 (en) | 2000-08-15 | 2002-04-18 | Cpd, Llc | Method of treating the syndrome of type 2 diabetes in humans |
EP1353665A4 (en) | 2000-12-21 | 2004-05-06 | Mclean Hospital Corp | TREATMENT OF DEPRESSION |
US7666876B2 (en) | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
CN100537564C (zh) * | 2003-04-04 | 2009-09-09 | 麦克公司 | 代谢型谷氨酸受体-5的二芳基取代三唑调节剂 |
BRPI0508254A (pt) * | 2004-03-02 | 2007-07-24 | Pharmacia Corp | métodos e composições para o tratamento ou prevenção de distúrbios psiquiátricos com inibidores de cox-2 sozinhos e em combinação com agentes antidepressivos |
BRPI0510406A (pt) * | 2004-05-26 | 2007-12-26 | Inotek Pharmaceuticals Corp | derivados de purina como agonistas do receptor de adenosina a1 e métodos de uso destes |
DE602004017514D1 (de) | 2004-06-02 | 2008-12-11 | Galephar M F | Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davon |
-
2007
- 2007-04-03 DK DK07727719.2T patent/DK2001456T3/da active
- 2007-04-03 WO PCT/EP2007/053248 patent/WO2007115975A2/de active Application Filing
- 2007-04-03 ES ES07727719T patent/ES2337622T3/es active Active
- 2007-04-03 AT AT07727719T patent/ATE450256T1/de active
- 2007-04-03 SI SI200730163T patent/SI2001456T1/sl unknown
- 2007-04-03 EP EP07727719A patent/EP2001456B1/de active Active
- 2007-04-03 PT PT07727719T patent/PT2001456E/pt unknown
- 2007-04-03 JP JP2009503576A patent/JP5128578B2/ja not_active Expired - Fee Related
- 2007-04-03 AU AU2007236003A patent/AU2007236003B2/en not_active Ceased
- 2007-04-03 EA EA200802104A patent/EA014820B1/ru not_active IP Right Cessation
- 2007-04-03 US US12/296,125 patent/US8063059B2/en not_active Expired - Fee Related
- 2007-04-03 PL PL07727719T patent/PL2001456T3/pl unknown
- 2007-04-03 CA CA2646899A patent/CA2646899C/en not_active Expired - Fee Related
- 2007-04-03 RS RSP-2010/0089A patent/RS51211B/sr unknown
- 2007-04-03 DE DE502007002185T patent/DE502007002185D1/de active Active
-
2010
- 2010-02-25 CY CY20101100188T patent/CY1109862T1/el unknown
- 2010-03-02 HR HR20100113T patent/HRP20100113T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
CA2646899C (en) | 2014-05-06 |
DK2001456T3 (da) | 2010-04-12 |
ATE450256T1 (de) | 2009-12-15 |
JP2009532434A (ja) | 2009-09-10 |
US8063059B2 (en) | 2011-11-22 |
CY1109862T1 (el) | 2014-09-10 |
US20090181999A1 (en) | 2009-07-16 |
EP2001456A2 (de) | 2008-12-17 |
EA014820B1 (ru) | 2011-02-28 |
SI2001456T1 (sl) | 2010-04-30 |
AU2007236003B2 (en) | 2012-10-18 |
WO2007115975A3 (de) | 2008-02-14 |
DE502007002185D1 (de) | 2010-01-14 |
ES2337622T3 (es) | 2010-04-27 |
CA2646899A1 (en) | 2007-10-18 |
RS51211B (sr) | 2010-12-31 |
AU2007236003A1 (en) | 2007-10-18 |
JP5128578B2 (ja) | 2013-01-23 |
EP2001456B1 (de) | 2009-12-02 |
PT2001456E (pt) | 2010-03-03 |
WO2007115975A2 (de) | 2007-10-18 |
PL2001456T3 (pl) | 2010-05-31 |
EA200802104A1 (ru) | 2009-04-28 |
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